{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T15:53:34Z","timestamp":1782921214433,"version":"3.54.5"},"reference-count":32,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Osteopathic manipulative treatment (OMT) is an integrative modality that has proven benefits for patients suffering from physical and psychological ailments. Though the impact of OMT has been preliminarily studied in various patient populations, research and implementation of this treatment option has been limited. Within palliative medicine, integrating OMT into treatment plans can help to address both the physical and non-physical burdens of serious illness.<\/jats:p>","DOI":"10.3389\/fmed.2026.1894142","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T15:37:15Z","timestamp":1782920235000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["A hands-on approach to personalizing palliative care: the role of osteopathic manipulative treatment"],"prefix":"10.3389","volume":"13","author":[{"given":"Megan","family":"Bryant","sequence":"first","affiliation":[{"name":"Clinical Center (NIH)","place":["Bethesda, MD, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikayla","family":"Dennison","sequence":"additional","affiliation":[{"name":"Clinical Center (NIH)","place":["Bethesda, MD, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Kim","sequence":"additional","affiliation":[{"name":"Clinical Center (NIH)","place":["Bethesda, MD, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,7,1]]},"reference":[{"key":"ref1","volume-title":"The Pocket Manual of OMT","author":"Beatty","year":"2010"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1016\/j.jpainsymman.2021.11.002","article-title":"Do palliative care providers use complementary and integrative medicine? A Nationwide survey","volume":"63","author":"Goel","year":"2022","journal-title":"J Pain Symptom Manag"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.math.2012.05.002","article-title":"Osteopathic manipulative treatment in obese patients with chronic low back pain: a pilot study","volume":"17","author":"Vismara","year":"2012","journal-title":"Man Ther"},{"key":"ref4","first-page":"321","article-title":"Osteopathic manipulative treatment in conjunction with medication relieves pain associated with fibromyalgia syndrome: results of a randomized clinical pilot project","volume":"102","author":"Gamber","year":"2002","journal-title":"J Am Osteopath Assoc"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1089\/acm.2012.0354","article-title":"Osteopathic treatment of patients with long-term sequelae of whiplash injury: effect on neck pain disability and quality of life","volume":"19","author":"Schwerla","year":"2013","journal-title":"J Altern Complement Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"6321","DOI":"10.3390\/cancers13246321","article-title":"Osteopathic treatment and evaluation in the clinical setting of childhood hematological malignancies","volume":"13","author":"Barbieri","year":"2021","journal-title":"Cancer"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e1239","DOI":"10.1097\/PR9.0000000000001239","article-title":"Effect of osteopathic manipulative treatment on pain in palliative care patients: a randomized placebo-controlled clinical trial","volume":"10","author":"Galeazzi","year":"2025","journal-title":"Pain Rep"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"596","DOI":"10.7556\/jaoa.2012.112.9.596","article-title":"Associations of cytokine concentrations with key osteopathic lesions and clinical outcomes in patients with nonspecific chronic low back pain: results from the OSTEOPATHIC trial","volume":"112","author":"Licciardone","year":"2012","journal-title":"J Osteopath Med"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"103043","DOI":"10.1016\/j.ctim.2024.103043","article-title":"Reported biological effects following osteopathic manipulative treatment: a comprehensive mapping review","volume":"82","author":"Dal Farra","year":"2024","journal-title":"Complement Ther Med"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.explore.2020.09.006","article-title":"Evidence-based assessment of potential therapeutic effects of adjunct osteopathic medicine for multidisciplinary care of acute and convalescent COVID-19 patients","volume":"17","author":"Marin","year":"2021","journal-title":"Explore (NY)"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"2336","DOI":"10.1200\/JCO.24.00542","article-title":"Palliative care for patients with cancer: ASCO guideline update","volume":"42","author":"Sanders","year":"2024","journal-title":"J Clin Oncol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"3998","DOI":"10.1200\/JCO.22.01357","article-title":"Integrative medicine for pain management in oncology: society for integrative oncology\u2013ASCO guideline","volume":"40","author":"Mao","year":"2022","journal-title":"J Clin Oncol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1177\/1534735418796954","article-title":"Osteopathic manipulative treatment effect on pain relief and quality of life in oncology geriatric patients: a nonrandomized controlled clinical trial","volume":"17","author":"Arienti","year":"2018","journal-title":"Integr Cancer Ther"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2021\/6678184","article-title":"Clinical evidence for the effects of manual therapy on cancer pain: a systematic review and meta-analysis","volume":"2021","author":"Yao","year":"2021","journal-title":"Evid Based Complement Alternat Med"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"385","DOI":"10.3390\/cancers18030385","article-title":"Use of instrumental physical therapies and manual therapy in Cancer patients: a systematic review","volume":"18","author":"Barni","year":"2026","journal-title":"Cancer"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.ejogrb.2019.08.003","article-title":"Visceral osteopathic manipulative treatment reduces patient reported digestive toxicities induced by adjuvant chemotherapy in breast cancer: a randomized controlled clinical study","volume":"241","author":"Lagrange","year":"2019","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"10453","DOI":"10.1007\/s00520-022-07404-9","article-title":"Integrating pharmacogenomics into precision pain management","volume":"30","author":"Bates","year":"2022","journal-title":"Support Care Cancer"},{"key":"ref18","first-page":"15","article-title":"Adult cancer pain, version 1.2026, NCCN clinical practice guidelines in oncology","author":"Youngwerth","year":"2026"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1200\/JCO.22.02198","article-title":"Use of opioids for adults with pain from cancer or cancer treatment: ASCO guideline","volume":"41","author":"Paice","year":"2022","journal-title":"J Clin Oncol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"E611","DOI":"10.36076\/ppj.2018.6.E611","article-title":"Fundamental considerations for genetically-guided pain management with opioids based on CYP2D6 and OPRM1 polymorphisms","volume":"1","author":"Ruano","year":"2018","journal-title":"Pain Physician"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1038\/s41562-024-01841-8","article-title":"A systematic review and multivariate meta-analysis of the physical and mental health benefits of touch interventions","volume":"8","author":"Packheiser","year":"2024","journal-title":"Nat Hum Behav"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"e095933","DOI":"10.1136\/bmjopen-2024-095933","article-title":"Effects of manual osteopathic interventions on psychometric and psychophysiological indicators of anxiety, depression and stress in adults: a systematic review and meta-analysis of randomised controlled trials","volume":"15","author":"Gordon","year":"2025","journal-title":"BMJ Open"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1002\/pmrj.12732","article-title":"The effects of osteopathic manipulative treatment on pain and disability in patients with chronic neck pain: a single-blinded randomized controlled trial","volume":"14","author":"Cholewicki","year":"2022","journal-title":"PM R"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/j.ctim.2014.05.007","article-title":"Quality of life in patients referring to private osteopathic clinical practice: a prospective observational study","volume":"22","author":"Cerritelli","year":"2014","journal-title":"Complement Ther Med"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"3627","DOI":"10.1007\/s00520-018-4233-y","article-title":"The perceptions and experiences of osteopathic treatment among cancer patients in palliative care: a qualitative study","volume":"26","author":"Steel","year":"2018","journal-title":"Support Care Cancer"},{"key":"ref26","year":"2026"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.2147\/JPR.S183170","article-title":"Osteopathic manipulation in the management of chronic pain: current perspectives","volume":"13","author":"Licciardone","year":"2020","journal-title":"J Pain Res"},{"key":"ref28","author":"Schierhorn","year":"2013"},{"key":"ref29","author":"Loveless","year":"2025"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"e0330219","DOI":"10.1371\/journal.pone.0330219","article-title":"Barriers to osteopathic manipulative medicine use: a qualitative study of physician attitudes and experiences","volume":"20","author":"Stacey","year":"2025","journal-title":"PLoS One"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1186\/s12906-025-05157-6","article-title":"Evaluation of integrative oncology modalities for symptom management: a MASCC\/SIO global survey","volume":"25","author":"Chan","year":"2025","journal-title":"BMC Complementary Med Ther"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1007\/s00520-020-05612-9","article-title":"Supportive care and osteopathic medicine in pediatric oncology: perspectives of current oncology clinicians, caregivers, and patients","volume":"29","author":"Belsky","year":"2021","journal-title":"Support Care Cancer"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1894142\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T15:37:16Z","timestamp":1782920236000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1894142\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,1]]},"references-count":32,"alternative-id":["10.3389\/fmed.2026.1894142"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2026.1894142","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,1]]},"article-number":"1894142"}}