{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T06:12:18Z","timestamp":1788415938898,"version":"build-2803163510"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>We report a case of a 62-year-old woman presenting with a 6-year history of purpuric patches and macules on the lower extremities, initially misdiagnosed as allergic purpura and treated with prednisone. Skin biopsy revealed dilated dermal vessels with perivascular collagen deposition, positive for collagen IV and diastase\u2013periodic acid\u2013Schiff (D-PAS) staining, consistent with cutaneous collagenous vasculopathy (CCV). Treatment included hydroxychloroquine, vitamin C, doxepin, and topical mucopolysaccharide polysulfate cream. Prednisone was tapered by one tablet every 3\u202fdays. After 4\u202fweeks, the rash improved significantly with no new lesions. We would like to present a case of CCV.<\/jats:p>","DOI":"10.3389\/fmed.2026.1899277","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:13:50Z","timestamp":1788412430000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: A case of cutaneous collagenous vasculopathy"],"prefix":"10.3389","volume":"13","author":[{"given":"Chenjian","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Acupuncture, Hospital of Chengdu University of Traditional Chinese Medicine","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, People\u2019s North Road Community Health Service Center (The Second People's Hospital of Jinniu District)","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangxiu","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Ba Zhong Hospital of Integrated Traditional Chinese and Western Medicine","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine","place":["Chengdu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1034\/j.1600-0560.2000.027001040.x","article-title":"Cutaneous collagenous vasculopathy with generalized telangiectasia: an immunohistochemical and ultrastructural study","volume":"27","author":"Salama","year":"2000","journal-title":"J Cutan Pathol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"e241434","DOI":"10.1136\/bcr-2020-241434","article-title":"Cutaneous collagenous vasculopathy","volume":"14","author":"Stavrou","year":"2021","journal-title":"BMJ Case Rep"},{"key":"ref3","first-page":"629","article-title":"A case of cutaneous collagen vascular disease","volume":"54","author":"Liu","year":"2021","journal-title":"Chin J Dermatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1097\/DAD.0000000000000613","article-title":"Cutaneous collagenous vasculopathy: report of two cases presenting as disseminated telangiectasias and review of the literature","volume":"39","author":"Bondier","year":"2017","journal-title":"Am J Dermatopathol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1111\/ajd.12444","article-title":"Cutaneous collagenous vasculopathy: report of first Japanese case and review of the literature","volume":"58","author":"Motegi","year":"2017","journal-title":"Australas J Dermatol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.36849\/jdd.7904","article-title":"Cutaneous collagenous vasculopathy treated with pulsed dye laser: a case series and literature review","volume":"23","author":"Weinberg","year":"2024","journal-title":"J Drugs Dermatol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"2283","DOI":"10.3390\/jcm10112283","article-title":"Pigmented purpuric dermatoses: a complete narrative review","volume":"10","author":"Spigariolo","year":"2021","journal-title":"J Clin Med"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1111\/cup.12285","article-title":"Cutaneous collagenous vasculopathy associated with intravascular occlusive fibrin thrombi","volume":"41","author":"Salama","year":"2014","journal-title":"J Cutan Pathol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"e97","DOI":"10.1111\/ajd.12330","article-title":"A rare case of cutaneous collagenous vasculopathy","volume":"57","author":"Meah","year":"2016","journal-title":"Australas J Dermatol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1097\/dad.0000000000002662","article-title":"Cutaneous collagenous vasculopathy: a short case series and literature review","volume":"46","author":"Kodali","year":"2024","journal-title":"Am J Dermatopathol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1111\/cup.14192","article-title":"Cutaneous collagenous vasculopathy: a report of three cases","volume":"49","author":"Grossman","year":"2022","journal-title":"J Cutan Pathol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1359","DOI":"10.1111\/j.1365-4632.2011.05237.x","article-title":"Cutaneous collagenous vasculopathy successfully treated with pulsed dye laser","volume":"51","author":"Echeverria","year":"2012","journal-title":"Int J Dermatol"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1111\/ddg.13311","article-title":"Cutaneous collagenous vasculopathy\u2014remission of perivascular deposits after pulsed dye laser therapy","volume":"15","author":"Mitteldorf","year":"2017","journal-title":"J Dtsch Dermatol Ges"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"e58391","DOI":"10.7759\/cureus.58391","article-title":"Cutaneous collagenous vasculopathy: a rare entity treated with pulsed dye laser","volume":"16","author":"Maniam","year":"2024","journal-title":"Cureus"},{"key":"ref15","first-page":"899","article-title":"Cutaneous collagenous vasculopathy: a case report","volume":"41","author":"Guo","year":"2025","journal-title":"Chin J Lepr Skin Dis"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1899277\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:13:52Z","timestamp":1788412432000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1899277\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,3]]},"references-count":15,"alternative-id":["10.3389\/fmed.2026.1899277"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2026.1899277","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,3]]},"article-number":"1899277"}}