{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T04:32:07Z","timestamp":1786422727303,"version":"build-2736575974"},"reference-count":16,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>Striae gravidarum (SG) is a form of striae distensae for which no single modality reliably and completely corrects the lesions, and high-level evidence remains limited. This study evaluated the clinical outcomes and safety of the 1540-nm non-ablative fractional Er:glass laser (NAFL) for SG and aimed to add real-world data in Chinese (Fitzpatrick III\u2013IV) women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed the first cohort of consecutive postpartum women with abdominal SG who began 1540-nm NAFL treatment in our department on 31 March 2022. Efficacy was independently graded by three dermatologists who were blinded to treatment details, using a quartile improvement scale (0\u20133) and the 5-point Global Aesthetic Improvement Scale (GAIS); the three ratings were averaged, and inter-rater agreement was assessed with the intraclass correlation coefficient (ICC). Patient-reported satisfaction (5-point unipolar scale), pain, and adverse events were also recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eight patients were analyzed. The mean quartile improvement score was 1.79 \u00b1 0.78 (corresponding to mild-to-moderate improvement) and the mean GAIS was 2.29 \u00b1 0.88 (between \u201cimproved\u201d and \u201cmuch improved\u201d). Inter-rater agreement was good to excellent (ICC = 0.82 and 0.93, respectively). All patients reported satisfaction with the outcome. Adverse events were limited to tolerable intraprocedural pain, transient erythema, subcutaneous petechiae (1 patient), and post-inflammatory hyperpigmentation (3 patients), all of which resolved.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this small, uncontrolled series, the 1540-nm NAFL appeared to be well tolerated and may provide cosmetic improvement in SG. These preliminary observations require confirmation in larger, controlled studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1902791","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T04:21:07Z","timestamp":1786422067000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Non-ablative fractional 1540-nm Er:glass laser for the treatment of striae gravidarum: a case series"],"prefix":"10.3389","volume":"13","author":[{"given":"Si-Ning","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Dermatology, The Second Affiliated Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixian","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Second Affiliated Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyue","family":"Qiang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Second Affiliated Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujuan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Second Affiliated Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Second Affiliated Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui-Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Second Affiliated Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/s0733-8635(03)00046-9","article-title":"Laser therapy of stretch marks.","volume":"20","author":"McDaniel","year":"2002","journal-title":"Dermatol Clin."},{"key":"B2","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1111\/bjd.12681","article-title":"Striae distensae: a comprehensive review and evidence-based evaluation of prophylaxis and treatment.","volume":"170","author":"Al-Himdani","year":"2014","journal-title":"Br J Dermatol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"e22256","DOI":"10.1097\/MD.0000000000022256","article-title":"Comparative effectiveness of different therapies for treating striae distensae: a systematic review and network 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Angelis","year":"2011","journal-title":"Aesthet Surg J."},{"key":"B10","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1046\/j.1524-4725.2003.29150.x","article-title":"A randomized, double-blind, multicenter comparison of the efficacy and tolerability of restylane versus zyplast for the correction of nasolabial folds.","volume":"29","author":"Narins","year":"2003","journal-title":"Dermatol Surg."},{"key":"B11","doi-asserted-by":"publisher","first-page":"2452","DOI":"10.1007\/s00266-022-02866-y","article-title":"Efficacy of early application of 1540 nm non-ablative fractional laser and silicones to improve post-epicanthoplasty scars.","volume":"46","author":"Zhang","year":"2022","journal-title":"Aesthetic Plast Surg."},{"key":"B12","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1097\/DSS.0000000000000629","article-title":"Evaluation of a 1540-nm and a 1410-nm nonablative fractionated laser for the treatment of striae.","volume":"42","author":"Wang","year":"2016","journal-title":"Dermatol Surg."},{"key":"B13","doi-asserted-by":"publisher","first-page":"143","DOI":"10.3109\/14764172.2014.1003243","article-title":"Striae after topical corticosteroid: treatment with nonablative fractional laser 1540nm.","volume":"17","author":"Alves","year":"2015","journal-title":"J Cosmet Laser Ther."},{"key":"B14","first-page":"194","article-title":"The safety and efficacy of the 1540 nm non-ablative fractional XD probe of Star Lux 500 device in the treatment of striae alba: before-after study.","volume":"5","author":"Malekzad","year":"2014","journal-title":"J Lasers Med Sci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"481","DOI":"10.5021\/ad.2011.23.4.481","article-title":"Treatment of striae distensae with nonablative fractional laser versus ablative CO2 fractional laser: a randomized controlled trial.","volume":"23","author":"Yang","year":"2011","journal-title":"Ann Dermatol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"2076","DOI":"10.1007\/s00266-024-04560-7","article-title":"Effects of nanofat and PRP on type I collagen production in striae distensae: preliminary findings from a prospective, randomized single-blind study.","volume":"49","author":"La Padula","year":"2025","journal-title":"Aesthetic Plast Surg."}],"container-title":["Frontiers in 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