{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:53:37Z","timestamp":1791186817085,"version":"4.1.0"},"reference-count":32,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the postoperative visual function, intraocular lens (IOL) positional stability and ocular safety of surgical strategies tailored to capsular support status for the treatment of IOL dislocation in patients with high myopia, and to explore the potential impact of such complex surgeries on macular microcirculation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single-center retrospective included 28 patients (28 eyes) with high myopia and IOL dislocation who underwent surgical treatment from January 2024 to August 2025. Surgical approaches were selected based on preoperative anatomical conditions and capsular status, including IOL explantation without secondary IOL implantation in 10 eyes, in-the-bag IOL repositioning in 6 eyes, and sutured scleral fixation of a posterior chamber IOL in 12 eyes. The primary outcome measures were uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), and IOL tilt and decentration before surgery and at 6 months postoperatively. Safety measures included intraocular pressure (IOP), corneal endothelial cell density (ECD), postoperative complications. Postoperative retinal microcirculation parameters assessed by WF-OCTA were included as exploratory outcomes. Whereas the IOL-position comparison included only the 18 operated eyes retaining an IOL and their corresponding 18 matched control eyes. Before quantitative analysis, all OCTA images were reviewed for image quality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared with preoperative values, UDVA (0.59\u2009\u00b1\u20090.46 logMAR,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.005) and CDVA (0.38\u2009\u00b1\u20090.59 logMAR,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.031) were significantly improved at 6 months postoperatively. Postoperative IOL position was evaluated in the 18 eyes retaining an IOL; 3 (16.7%) exceeded the 6\u00b0 tilt threshold and 2 (11.1%) exceeded the 0.6\u2005mm decentration threshold. The postoperative 2D tilt of IOL was 4.51\u2009\u00b1\u20092.17\u00b0, 2D decentration was 0.45\u2009\u00b1\u20090.33\u2005mm, 3D tilt was 4.41\u2009\u00b1\u20092.09\u00b0, and 3D decentration was 0.44\u2009\u00b1\u20090.34\u2005mm. Corneal ECD decreased from 2672.72\u2009\u00b1\u2009312.26 cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      preoperatively to 2356.61\u2009\u00b1\u2009420.15 cells\/mm\n                      <jats:sup>2<\/jats:sup>\n                      postoperatively (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001), yet no corneal decompensation occurred. IOP remained stable during the follow-up period, and the incidence of complications was low. Regional WF-OCTA parameters varied between the operated and matched control eyes, without a consistent pattern across macular regions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In patients with high myopia and IOL dislocation, different surgical approaches can achieve stable intraocular optical reconstruction and improve mid-to-long-term visual function under the corresponding anatomical conditions. Although the magnitude of visual acuity improvement is limited in this population due to high myopia- related high-risk fundus factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1922084","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:13:41Z","timestamp":1791184421000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Surgical management of intraocular lens dislocation in highly myopic eyes"],"prefix":"10.3389","volume":"13","author":[{"given":"Shiyu","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Shanghai Tenth People\u2019s Hospital","place":["Shanghai, China"]},{"name":"Visual Rehabilitation Center, Tongji University School of Medicine","place":["Shanghai, China"]},{"name":"Tongji Eye Institute, Tongji University School of Medicine","place":["Shanghai, 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China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuye","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Shanghai Tenth People\u2019s Hospital","place":["Shanghai, China"]},{"name":"Visual Rehabilitation Center, Tongji University School of Medicine","place":["Shanghai, China"]},{"name":"Tongji Eye Institute, Tongji University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenting","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Shanghai Tenth People\u2019s Hospital","place":["Shanghai, China"]},{"name":"Visual Rehabilitation Center, Tongji University School of Medicine","place":["Shanghai, China"]},{"name":"Tongji Eye Institute, Tongji University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyu","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Shanghai Tenth People\u2019s Hospital","place":["Shanghai, China"]},{"name":"Visual Rehabilitation Center, Tongji University School of Medicine","place":["Shanghai, China"]},{"name":"Tongji Eye Institute, Tongji University School of Medicine","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"4053","DOI":"10.2147\/OPTH.S556153","article-title":"Surgical techniques and indications for intraocular lens explantation: a narrative review","volume":"19","author":"Alkhatib","year":"2025","journal-title":"Clin Ophthalmol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.1056\/NEJMicm2032935","article-title":"Intraocular lens 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