{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T05:05:26Z","timestamp":1789707926208,"version":"4.0.1"},"reference-count":50,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To investigate the association between peripheral retinal lesions (PRLs) and ocular biometric parameters in adults with mild-to-moderate myopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cross-sectional study included 106 adults who contributed 171 eligible eyes with mild-to-moderate myopia. Based on dilated fundus examination and ultra-widefield imaging, 70 eyes were assigned to the PRL group and 101 eyes to the normal-fundus (NF) group. Participant age and eye-level spherical equivalent (SE), axial length (AL), mean corneal power (Km), corneal curvature radius (CR), and the exploratory corneal-curvature-adjusted parameter SEAL were compared. Eye-level continuous comparisons used participant-clustered robust standard errors. Lesion types and quadrant distributions were recorded descriptively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean age did not differ between the groups (21.17\u2009\u00b1\u20093.76 vs. 22.04\u2009\u00b1\u20093.13 years,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.200). SE was also similar (\u22124.23\u2009\u00b1\u20091.26 vs. \u22124.20\u2009\u00b1\u20091.07\u2005D,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.913). Compared with NF eyes, PRL eyes had a longer AL (26.39\u2009\u00b1\u20090.87 vs. 24.78\u2009\u00b1\u20090.72\u2005mm,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001), lower Km (41.40\u2009\u00b1\u20090.90 vs. 44.51\u2009\u00b1\u20090.72\u2005D,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001), higher CR (8.16\u2009\u00b1\u20090.18 vs. 7.59\u2009\u00b1\u20090.12\u2005mm,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&amp;lt;\u20090.001), and a more negative SEAL value (\u22124.59\u2009\u00b1\u20091.42 vs. \u22123.95\u2009\u00b1\u20091.05\u2005D,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.009). White without pressure, lattice degeneration, and snowflake degeneration were the most frequent lesions. Quadrant involvement was most common superiorly, superotemporally, inferiorly, and inferotemporally.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this refractive-surgery-clinic sample, PRLs were associated at the eye level with longer AL, flatter corneas, and more negative exploratory SEAL values. Because the study was cross-sectional and did not include multivariable modeling, these findings do not establish independent predictors or causal relationships.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1929247","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:35:54Z","timestamp":1789706154000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between peripheral retinal lesions and ocular biometric parameters in adults with mild-to-moderate myopia attending a refractive surgery clinic"],"prefix":"10.3389","volume":"13","author":[{"given":"Zujian","family":"Zhu","sequence":"first","affiliation":[{"name":"Jiangsu Health Vocational College","place":["Nanjing, Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benqian","family":"Liu","sequence":"additional","affiliation":[{"name":"Lianyungang Eye Hospital","place":["Lianyungang, Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhentao","family":"Zhu","sequence":"additional","affiliation":[{"name":"Huai'an Clinical Medical College of Jiangsu University, Huaian Hospital of Huaian City","place":["Huaian, Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shandi","family":"Liu","sequence":"additional","affiliation":[{"name":"Huai'an Clinical Medical College of Jiangsu University, Huaian Hospital of Huaian City","place":["Huaian, Jiangsu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ligang","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Quzhou People\u2019s Hospital, The Quzhou Affiliated Hospital, Wenzhou Medical University","place":["Quzhou, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1038\/s41572-020-00231-4","article-title":"Myopia","volume":"6","author":"Baird","year":"2020","journal-title":"Nat Rev Dis Primers"},{"key":"B2","doi-asserted-by":"publisher","first-page":"6062","DOI":"10.3390\/jcm12186062","article-title":"Risk factors for myopia: a review","volume":"12","author":"Mart\u00ednez-Albert","year":"2023","journal-title":"J Clin Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.preteyeres.2017.09.004","article-title":"The epidemics of myopia: aetiology and prevention","volume":"62","author":"Morgan","year":"2018","journal-title":"Prog Retin Eye Res"},{"key":"B4","doi-asserted-by":"publisher","first-page":"100113","DOI":"10.1016\/j.apjo.2024.100113","article-title":"Is there an impending epidemic of myopia in Southeast Asia? 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