{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:29:31Z","timestamp":1787725771372,"version":"build-2784847793"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"2024 Capital Health Development Research Special Project","award":["2024-1-4063"],"award-info":[{"award-number":["2024-1-4063"]}]},{"name":"Beijing Municipal Plan for High-Level Innovative and Entrepreneurial Talents Project","award":["G202521169"],"award-info":[{"award-number":["G202521169"]}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Myelolipoma predominantly arises within the adrenal glands, while endobronchial myelolipoma is extremely rare and frequently leads to airway obstruction. We report a case of bronchial myelolipoma causing left lower lobe airway obstruction in a 62-year-old male who presented with cough and sputum. Chest computed tomography (CT) revealed a mixed-density lesion with calcification within the left lower lobe bronchial lumen, and the diagnosis was confirmed by bronchoscopic biopsy pathology. The patient underwent interventional minimally invasive interventional therapy under general anesthesia, employing flexible bronchoscopic electrosurgical snare resection combined with semiconductor laser ablation, which successfully removed the tumor and restored airway patency. We systematically reviewed the domestic and international literature and summarized all reported cases of bronchial myelolipoma (a total of 6 cases, including the present case), with a focus on the clinical decision-making basis for bronchoscopic interventional therapy versus surgical resection, and the technical considerations for selecting laser ablation over argon plasma coagulation (APC) and cryotherapy. This case demonstrates that electrosurgical snare combined with laser ablation is a safe and effective minimally invasive interventional treatment for airway obstruction caused by bronchial myelolipoma, providing a reference for the clinical diagnosis and management of this rare benign airway tumor.<\/jats:p>","DOI":"10.3389\/fmed.2026.1936465","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:01:25Z","timestamp":1787724085000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Multimodal interventional bronchoscopy for bronchial myelolipoma complicated with airway obstruction: a case report and literature review"],"prefix":"10.3389","volume":"13","author":[{"given":"Rongrong","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Chuiyangliu Hospital Affiliated to Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaxu","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Chuiyangliu Hospital Affiliated to Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Chuiyangliu Hospital Affiliated to Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Chuiyangliu Hospital Affiliated to Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Chuiyangliu Hospital Affiliated to Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Chuiyangliu Hospital Affiliated to Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Chuiyangliu Hospital Affiliated to Tsinghua University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"204","DOI":"10.5114\/pjp.2012.31507","article-title":"Primary myelolipoma of the lung: a case of report and review of literature","volume":"63","author":"Huang","year":"2012","journal-title":"Pol J Pathol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1186\/s12890-019-0910-y","article-title":"Bronchoscopic management of solitary bronchial myelolipoma: a case report","volume":"19","author":"Chung","year":"2019","journal-title":"BMC Pulm Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1186\/s12890-023-02608-z","article-title":"Bronchoscopic treatment of multiple bronchial myelolipomas: a case report and literature review","volume":"23","author":"Ji","year":"2023","journal-title":"BMC Pulm Med"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2647","DOI":"10.1016\/j.asjsur.2024.10.135","article-title":"Bronchial myelolipoma with fibroepithelial polyp: a rare cause of bronchial occlusion","volume":"48","author":"Yan","year":"2024","journal-title":"Asian J Surg"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"66","DOI":"10.12117\/jccmi.2024.01.015","article-title":"A case of endobronchial myelolipoma of the right bronchus","volume":"35","author":"Haiyan","year":"2024","journal-title":"J Chin Clin Med Imaging"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"366","DOI":"10.3969\/j.issn.1673-2588.2012.04.019","article-title":"Pulmonary myelolipoma with osseous and cartilaginous metaplasia: a case report","volume":"32","author":"Leiyu","year":"2012","journal-title":"Int J Pathol Clin Sci"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.3892\/ol.2015.2913","article-title":"Intrapulmonary myelolipoma and its computed tomography features: a case report and literature review","volume":"9","author":"Xu","year":"2015","journal-title":"Oncol Lett"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"644656","DOI":"10.3389\/fsurg.2021.644656","article-title":"Benign endobronchial tumors: a Clinicopathologic review","volume":"8","author":"Insler","year":"2021","journal-title":"Front Surg"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"190178","DOI":"10.1183\/16000617.0178-2019","article-title":"Therapeutic bronchoscopy for central airway diseases","volume":"29","author":"Rosell","year":"2020","journal-title":"Eur Respir Rev"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.chest.2024.06.3804","article-title":"Management of Central Airway Obstruction: an American College of Chest Physicians Clinical Practice Guideline","volume":"167","author":"Mahmood","year":"2025","journal-title":"Chest"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"E181","DOI":"10.3978\/j.issn.2072-1439.2014.07.34","article-title":"Primary myelolipoma in posterior mediastinum","volume":"6","author":"Xiong","year":"2014","journal-title":"J Thorac Dis"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.rmcr.2017.09.008","article-title":"Pulmonary myelolipoma containing osseous tissue: an unexpected finding at autopsy","volume":"22","author":"Ma\u0161i\u0107","year":"2017","journal-title":"Respir Med Case Rep"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/1471-2482-14-42","article-title":"A bilateral neoplasm in chest: a case report and literature review","volume":"14","author":"Shen","year":"2014","journal-title":"BMC Surg"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"3343","DOI":"10.21037\/jtd.2016.11.49","article-title":"Techniques of endoscopic airway tumor treatment","volume":"8","author":"Guibert","year":"2016","journal-title":"J Thorac Dis"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"iii1","DOI":"10.1136\/thoraxjnl-2011-200713","article-title":"British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults","volume":"66","author":"Du Rand","year":"2011","journal-title":"Thorax"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1016\/j.ejso.2015.08.157","article-title":"Endoscopic treatment of primary benign central airway tumors: results from a large consecutive case series and decision making flow chart to address bronchoscopic excision","volume":"41","author":"Scarlata","year":"2015","journal-title":"Eur J Surg Oncol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"362","DOI":"10.21037\/atm.2019.04.47","article-title":"Bronchoscopic ablation techniques in the management of lung cancer","volume":"7","author":"Shepherd","year":"2019","journal-title":"Ann Transl Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2019\/5269728","article-title":"Bronchoscopic treatment of benign Endoluminal lung tumors","volume":"2019","author":"Dalar","year":"2019","journal-title":"Can Respir J"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"240246","DOI":"10.1183\/20734735.0246-2024","article-title":"Fire: argon plasma coagulation, diathermy and laser","volume":"21","author":"Azmanov","year":"2025","journal-title":"Breathe (Sheff)"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"S380","DOI":"10.3978\/j.issn.2072-1439.2015.12.55","article-title":"Past, present, and future of endobronchial laser photoresection","volume":"7","author":"Khemasuwan","year":"2015","journal-title":"J Thorac Dis"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1936465\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:01:30Z","timestamp":1787724090000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1936465\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,26]]},"references-count":20,"alternative-id":["10.3389\/fmed.2026.1936465"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2026.1936465","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,26]]},"article-number":"1936465"}}