{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T06:07:42Z","timestamp":1789106862343,"version":"build-2803163510"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>\n                    <jats:italic>Streptococcus intermedius<\/jats:italic>\n                    is a gram-positive commensal associated with suppurative infections. Pediatric pulmonary abscesses due to\n                    <jats:italic>S. intermedius<\/jats:italic>\n                    are rare, and outcomes in children with severe neurological comorbidities are poorly characterized. A 5-year-old boy with refractory epilepsy and global developmental delay who presented with a right upper lobe abscess, pneumonitis, and pleural effusion. Targeted next-generation sequencing (tNGS) of bronchoalveolar lavage fluid (BALF), drainage pus culture, and tNGS of drainage pus all confirmed the presence of\n                    <jats:italic>S. intermedius<\/jats:italic>\n                    . To our knowledge, this is the first reported case of a residual pulmonary cavity on 3-month follow-up imaging after an\n                    <jats:italic>S. intermedius<\/jats:italic>\n                    lung abscess in a child with severe neurological impairment. Our findings highlight the value of tNGS in diagnosing lower respiratory tract infections caused by pathogens that are difficult to identify through conventional culture methods.\n                  <\/jats:p>","DOI":"10.3389\/fmed.2026.1948468","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T05:30:19Z","timestamp":1789104619000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Streptococcus intermedius lung abscess in children: a case report and literature review"],"prefix":"10.3389","volume":"13","author":[{"given":"Shuteng","family":"Ou","sequence":"first","affiliation":[{"name":"Department of Pediatrics, The First People\u2019s Hospital of Chenzhou","place":["Chenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhua","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The First People\u2019s Hospital of Chenzhou","place":["Chenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The First People\u2019s Hospital of Chenzhou","place":["Chenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The First People\u2019s Hospital of Chenzhou","place":["Chenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuping","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The First People\u2019s Hospital of Chenzhou","place":["Chenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yandong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, The First People\u2019s Hospital of Chenzhou","place":["Chenzhou, 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