{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:02:23Z","timestamp":1790744543724,"version":"4.1.0"},"reference-count":72,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Previous reviews have commonly pooled heterogeneous digital technologies, leaving the relative effects of different delivery approaches, feedback mechanisms, and levels of professional involvement unclear. This study compared seven exercise and self-management strategies for WOMAC pain, WOMAC physical function, and retention at the end of the intervention in people with knee osteoarthritis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Seven databases were searched through July 2026 for randomised controlled trials involving adults with knee osteoarthritis. Interventions were classified into seven nodes according to exercise delivery, feedback mechanisms, and professional involvement. Frequentist random-effects network meta-analyses were conducted, with WOMAC outcomes expressed as Hedges' g and retention as risk ratios. Risk of bias and certainty of evidence were assessed using RoB 2 and GRADE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-one RCTs involving 2,250 participants were included. The pain, physical function, and retention networks comprised 8, 12, and 20 trials, respectively. For physical function, D1 vs. C1 (g\u2009=\u20090.47, 95% CI 0.31 to 0.64) and D2 vs. C2 (g\u2009=\u20090.47, 95% CI 0.22 to 0.72) showed improvements, with moderate-certainty evidence. The estimate for D3 vs. C3 was imprecise (g\u2009=\u20090.48, 95% CI \u22120.13 to 1.10; low-certainty evidence). All three pain comparisons favoured the digitally supported nodes (g\u2009=\u20090.15, 0.21, and 0.50), but all 95% CIs included the null value, with low-certainty evidence. Retention differences for D2 vs. C2 and D3 vs. C3 were likely to be small, whereas local inconsistency was identified for D1 vs. C1.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Comparison-specific network estimates favoured D1 over C1 and D2 over C2 for patient-reported physical function, but these contrasts used different comparators and do not establish superiority of digital delivery itself or the independent value of professional support. The incremental value of synchronous or hybrid professional support over face-to-face supervised exercise remains uncertain. Incremental effects on WOMAC pain remain unclear, and retention estimates were generally close to the null, with local inconsistency for D1 vs. C1. Current evidence does not support prioritising synchronous or hybrid professional support solely on the basis of rankings or assuming a linear relationship between digital-support intensity and treatment effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Systematic Review Registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link>www.crd.york.ac.uk\/prospero<\/jats:ext-link>\n                      , identifier CRD420261467021.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2026.1956102","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:53:45Z","timestamp":1790744025000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative effectiveness of exercise and self-management interventions delivered through different modes of digital support on pain and patient-reported physical function in people with knee osteoarthritis: a systematic review and network meta-analysis of randomised controlled trials"],"prefix":"10.3389","volume":"13","author":[{"given":"Hao","family":"Luo","sequence":"first","affiliation":[{"name":"Department of Physical Education, Chongqing Electric Power College","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Physical Education, Chongqing Electric Power College","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Long","sequence":"additional","affiliation":[{"name":"Department of Physical Education, Chongqing Electric Power College","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjia","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Physical Education, China University of Mining and Technology","place":["Xuzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Yao","sequence":"additional","affiliation":[{"name":"School of Physical Education, China University of Mining and Technology","place":["Xuzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Physical Education, Chongqing Electric Power College","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e508","DOI":"10.1016\/S2665-9913(23)00163-7","article-title":"Global, regional, and national burden of osteoarthritis, 1990\u20132020 and projections to 2050: a systematic analysis for the global burden of disease study 2021","volume":"5","author":"Steinmetz","year":"2023","journal-title":"Lancet Rheumatol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1002\/art.42089","article-title":"Prevalence trends of site-specific osteoarthritis from 1990 to 2019: findings from the global burden of disease study 2019","volume":"74","author":"Long","year":"2022","journal-title":"Arthritis Rheumatol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1759720X241273009","DOI":"10.1177\/1759720X241273009","article-title":"Knee osteoarthritis: disease burden, available treatments, and emerging options","volume":"16","author":"Langworthy","year":"2024","journal-title":"Ther Adv Musculoskelet Dis"},{"key":"B4","year":""},{"key":"B5","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1136\/ard-2023-225041","article-title":"EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis: 2023 update","volume":"83","author":"Moseng","year":"2024","journal-title":"Ann Rheum Dis"},{"key":"B6","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1016\/j.joca.2022.10.009","article-title":"Recommendations for the delivery of therapeutic exercise for people with knee and\/or hip osteoarthritis. 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