{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T05:05:50Z","timestamp":1789967150245,"version":"4.0.1"},"reference-count":8,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"DOI":"10.3389\/fmed.2026.1987693","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T04:29:26Z","timestamp":1789964966000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Editorial: Perioperative management and clinical challenges in elderly major surgical patients"],"prefix":"10.3389","volume":"13","author":[{"given":"Giuseppe","family":"Corazzelli","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Santa Maria Delle Grazie Hospital, ASL Napoli 2 Nord","place":["Pozzuoli, Italy"]},{"name":"Department of Human Neurosciences, Sapienza University of Rome","place":["Rome, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Corvino","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Presidio Ospedaliero \u201cOspedale del Mare\u201d","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennaro","family":"De Rosa","sequence":"additional","affiliation":[{"name":"Department of Advanced Biomedical Sciences, University of Naples Federico II","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Fiore","sequence":"additional","affiliation":[{"name":"Department of Translational Medical Sciences, University of Naples Federico II","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Filippelli","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, University of Naples Federico II","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Sigona","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Santa Maria Delle Grazie Hospital, ASL Napoli 2 Nord","place":["Pozzuoli, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Bocchetti","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Santa Maria Delle Grazie Hospital, ASL Napoli 2 Nord","place":["Pozzuoli, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Di Colandrea","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Medicine, Santa Maria Delle Grazie Hospital, ASL Napoli 2 Nord","place":["Pozzuoli, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oreste","family":"de Divitiis","sequence":"additional","affiliation":[{"name":"Department of Neurosciences and Reproductive and Odontostomatological Sciences, Neurosurgical Clinic, University of Naples Federico II","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo Gabriele","family":"Tocchetti","sequence":"additional","affiliation":[{"name":"Department of Translational Medical Sciences, University of Naples Federico II","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Fiorelli","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine, Thoracic Surgery Unit, University of Campania \u201cLuigi Vanvitelli\u201d","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Mormile","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, University of Naples Federico II","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Cuomo","sequence":"additional","affiliation":[{"name":"Department of Translational Medical Sciences, University of Naples Federico II","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Plinio","family":"Cirillo","sequence":"additional","affiliation":[{"name":"Department of Advanced Biomedical Sciences, University of Naples Federico II","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Paolini","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, IRCCS Neuromed, Pozzilli","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gualtiero","family":"Innocenzi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, IRCCS Neuromed, Pozzilli","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Esposito","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, IRCCS Neuromed, Pozzilli","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"de Falco","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Santa Maria Delle Grazie Hospital, ASL Napoli 2 Nord","place":["Pozzuoli, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/j.jamcollsurg.2012.06.017","article-title":"Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American college of surgeons national surgical quality improvement program and the American geriatrics society","volume":"215","author":"Chow","year":"2012","journal-title":"J Am Coll Surg"},{"key":"B2","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1016\/S0140-6736(12)62167-9","article-title":"Frailty in elderly people","volume":"381","author":"Clegg","year":"2013","journal-title":"Lancet"},{"key":"B3","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1186\/s12877-016-0329-8","article-title":"Frailty and post-operative outcomes in older surgical patients: a systematic review","volume":"16","author":"Lin","year":"2016","journal-title":"BMC Geriatr"},{"key":"B4","doi-asserted-by":"publisher","first-page":"4104","DOI":"10.1007\/s00464-024-10977-7","article-title":"EAES\/SAGES evidence-based recommendations and expert consensus on optimization of perioperative care in older adults","volume":"38","author":"Keller","year":"2024","journal-title":"Surg Endosc"},{"key":"B5","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1097\/EJA.0000000000001876","article-title":"Update of the European society of anaesthesiology and intensive care medicine evidence-based and consensus-based guideline on postoperative delirium in adult patients","volume":"41","author":"Aldecoa","year":"2024","journal-title":"Eur J Anaesthesiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1322","DOI":"10.1227\/neu.0000000000003494","article-title":"Management of anticoagulant and antiplatelet therapy in elective degenerative lumbosacral spine surgery: a clinical study on 578 elderly patients","volume":"97","author":"Corazzelli","year":"2025","journal-title":"Neurosurgery"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1007\/s40520-020-01624-x","article-title":"Perioperative management of elderly patients (PriME): recommendations from an Italian intersociety consensus","volume":"32","author":"Aceto","year":"2020","journal-title":"Aging Clin Exp Res"},{"key":"B8","doi-asserted-by":"publisher","first-page":"e0306308","DOI":"10.1371\/journal.pone.0306308","article-title":"The impact of comprehensive geriatric assessment on postoperative outcomes in elderly surgery: a systematic review and meta-analysis","volume":"19","author":"Chen","year":"2024","journal-title":"PLoS One"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1987693\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T04:29:27Z","timestamp":1789964967000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2026.1987693\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,21]]},"references-count":8,"alternative-id":["10.3389\/fmed.2026.1987693"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2026.1987693","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,21]]},"article-number":"1987693"}}