{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:36:28Z","timestamp":1790339788475,"version":"4.1.0"},"reference-count":54,"publisher":"Frontiers Media SA","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2015.00057","type":"journal-article","created":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T15:50:53Z","timestamp":1424188253000},"source":"Crossref","is-referenced-by-count":12,"title":["Role of integrons, plasmids and SXT elements in multidrug resistance of Vibrio cholerae and Providencia vermicola obtained from a clinical isolate of diarrhea"],"prefix":"10.3389","volume":"6","author":[{"given":"Neha","family":"Rajpara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Braj M. R. N. S.","family":"Kutar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritam","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhrubajyoti","family":"Nag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemanta","family":"Koley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thandavarayan","family":"Ramamurthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashima K.","family":"Bhardwaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2015,2,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"5137","DOI":"10.1093\/nar\/20.19.5137","article-title":"DNA diversity among clinical isolates of Helicobacter pylori detected by PCR-based RAPD fingerprinting.","volume":"20","author":"Akopyanz","year":"1992","journal-title":"Nucleic Acids Res."},{"key":"B2","doi-asserted-by":"crossref","DOI":"10.1201\/EBK1439804063","author":"Atlas","year":"2010","journal-title":"Handbook of Microbiological Media"},{"key":"B3","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.1007\/s000180200006","article-title":"Comparison of SXT and R391, two conjugative integrating elements: definition of a genetic backbone for the mobilization of resistance determinants.","volume":"59","author":"Beaber","year":"2002","journal-title":"Cell. Mol. Life Sci."},{"key":"B4","doi-asserted-by":"publisher","first-page":"73","DOI":"10.2174\/157489112799829710","article-title":"Bacterial e\u00ef\u00ac\u201eux pumps involved in multidrug resistance and their inhibitors: rejuvinating the antimicrobial chemotherapy.","volume":"7","author":"Bhardwaj","year":"2012","journal-title":"Recent Pat. Antiinfect. Drug Discov."},{"key":"B5","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1007\/978-81-322-1982-8_2","article-title":"\u00e2\u20ac\u0153Evolution of MDRs,\u00e2\u20ac\u009d in","author":"Bhardwaj","year":"2015","journal-title":"Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight"},{"key":"B6","doi-asserted-by":"publisher","first-page":"68","DOI":"10.2174\/1574891X11308010012","article-title":"Bacterial quorum sensing inhibitors: attractive alternatives for control of infectious pathogens showing multiple drug resistance.","volume":"8","author":"Bhardwaj","year":"2013","journal-title":"Recent Pat. Antiinfect. Drug Discov."},{"key":"B7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.2174\/9781608059126114030004","article-title":"\u00e2\u20ac\u0153Therapeutic limitations due to antibiotic drug resistance: road to alternate therapies,\u00e2\u20ac\u009d in","volume":"Vol. 3","author":"Bhardwaj","year":"2014","journal-title":"Frontiers in Anti-Infective Drug Discovery"},{"key":"B8","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.plasmid.2006.01.001","article-title":"The current ICE age: biology and evolution of SXT-related integrating conjugative elements.","volume":"55","author":"Burrus","year":"2006","journal-title":"Plasmid"},{"key":"B9","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.resmic.2004.01.012","article-title":"Shaping bacterial genomes with integrative and conjugative elements.","volume":"155","author":"Burrus","year":"2004","journal-title":"Res. Microbiol."},{"key":"B10","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1099\/0022-1317-50-10-879","article-title":"Comparison of antibiogram, virulence genes, ribotypes and DNA fingerprints of Vibrio cholerae of matching serogroups isolated from hospitalised diarrhoea cases and from the environment during 1997-1998 in Calcutta, India.","volume":"50","author":"Chakraborty","year":"2001","journal-title":"J. Med. Microbiol."},{"key":"B11","first-page":"M100","author":"CLSI.","year":"2010","journal-title":"Performance Standards for Antimicrobial Susceptibility Testing."},{"key":"B12","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1099\/00221287-72-3-543","article-title":"R factors from Proteus rettgeri.","volume":"72","author":"Coetzee","year":"1972","journal-title":"J. Gen. Microbiol."},{"key":"B13","doi-asserted-by":"crossref","first-page":"3774","DOI":"10.1128\/JCM.38.10.3774-3779.2000","article-title":"Class 1 integron-borne, multiple-antibiotic resistance encoded by a 150-kilobase conjugative plasmid in epidemic Vibrio cholerae O1 strains isolated in Guinea-Bissau.","volume":"38","author":"Dalsgaard","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1002\/path.1700660228","article-title":"An experimental study of the mechanism of action of Vibrio cholerae on the intestinal mucous membrane.","volume":"46","author":"De","year":"1953","journal-title":"J. Pathol. Bacteriol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1099\/00207713-41-2-324","article-title":"Phylogenetic analysis of Aquaspirillum magnetotacticum using polymerase chain reaction-amplified 16S rRNA-specific DNA.","volume":"41","author":"Eden","year":"1991","journal-title":"Int. J. syst. bacterial."},{"key":"B16","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1080\/00365540510026409","article-title":"Mixed diarrhoeal infection caused by Vibrio cholerae and several other enteric pathogens in a 4-year-old child returning to Germany from Pakistan.","volume":"37","author":"Enzensberger","year":"2005","journal-title":"Scand. J. Infect. Dis."},{"key":"B17","first-page":"214","article-title":"Severity of cholera during concurrent infections with other enteric pathogens.","volume":"12","author":"Faruque","year":"1994","journal-title":"J. Diarrhoeal Dis. Res."},{"key":"B18","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1128\/MMBR.62.4.1301-1314.1998","article-title":"Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae.","volume":"62","author":"Faruque","year":"1998","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"B19","doi-asserted-by":"publisher","first-page":"1020","DOI":"10.1128\/IAI.71.2.1020-1025.2003","article-title":"Pathogenic potential of environmental Vibrio cholerae strains carrying genetic variants of the toxin-coregulated pilus pathogenicity island.","volume":"71","author":"Faruque","year":"2003","journal-title":"Infect. Immun."},{"key":"B20","first-page":"225","article-title":"Antimicrobials and cholera: are we stranded?","volume":"133","author":"Ghosh","year":"2011","journal-title":"Indian J. Med. Res."},{"issue":"e87801","key":"B21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0087801","article-title":"Mobile insertion cassette elements found in small non-transmissible plasmids in proteeae may explain qnrD mobilization.","volume":"9","author":"Guillard","year":"2014","journal-title":"PLoS ONE"},{"key":"B22","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1038\/35020000","article-title":"DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.","volume":"406","author":"Heidelberg","year":"2000","journal-title":"Nature"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1128\/JB.183.4.1124-1132.2001","article-title":"Formation of chromosomal tandem arrays of the SXT element and R391, two conjugative chromosomally integrating elements that share an attachment site.","volume":"183","author":"Hochhut","year":"2001","journal-title":"J. Bacteriol."},{"key":"B24","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1128\/CMR.8.1.48","article-title":"Cholera.","volume":"8","author":"Kaper","year":"1995","journal-title":"Clin. Microbiol. Rev."},{"key":"B25","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1128\/JB.100.3.1393-1401.1969","article-title":"Fine structure of Vibrio cholerae during toxin production.","volume":"100","author":"Kennedy","year":"1969","journal-title":"J. Bacteriol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1016\/j.ophtha.2006.03.047","article-title":"Ocular infections caused by Providencia rettgeri.","volume":"113","author":"Koreishi","year":"2006","journal-title":"Ophthalmology"},{"key":"B27","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1097\/01.SMJ.0000141308.19657.BA","article-title":"Infective endocarditis due to Providenca stuartii.","volume":"97","author":"Krake","year":"2004","journal-title":"South. Med. J."},{"issue":"e56477","key":"B28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056477","article-title":"Clinical isolates of Vibrio cholerae O1 El Tor Ogawa of 2009 from Kolkata, India: preponderance of SXT element and presence of Haitian ctxB variant.","volume":"8","author":"Kutar","year":"2013","journal-title":"PLoS ONE"},{"key":"B29","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1038\/nature09354","article-title":"Bacterial charity work leads to population-wide resistance.","volume":"467","author":"Lee","year":"2010","journal-title":"Nature"},{"key":"B30","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/0042-6822(55)90016-7","article-title":"Transduction of linked genetic characters of the host by bacteriophage P1.","volume":"1","author":"Lennox","year":"1955","journal-title":"Virology"},{"key":"B31","author":"MacFaddin","year":"2000","journal-title":"Biochemical Tests for Identification of Medical Bacteria"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1099\/jmm.0.47395-0","article-title":"Species interactions in mixed-community crystalline biofilms on urinary catheters.","volume":"56","author":"Macleod","year":"2007","journal-title":"J. Med. Microbiol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1128\/AAC.45.4.1022-1029.2001","article-title":"Rapid screening technique for class 1 integrons in Enterobacteriaceae and non-fermenting gram-negative bacteria and its use in molecular epidemiology.","volume":"45","author":"Maguire","year":"2001","journal-title":"Antimicrob. Agents Chemother."},{"key":"B34","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1128\/AAC.43.8.2069","article-title":"TEM-24 produced by four different species of Enterobacteriaceae, including Providencia rettgeri, in a single patient.","volume":"43","author":"Marchandin","year":"1999","journal-title":"Antimicrob. Agents Chemother."},{"issue":"e35752","key":"B35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0035752","article-title":"Role of H- and D- MATE-type transporters from multidrug resistant clinical isolates of Vibrio fluvialis in conferring fluoroquinolone resistance.","volume":"7","author":"Mohanty","year":"2012","journal-title":"PLoS ONE"},{"key":"B36","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1128\/jcm.9.1.79-83.1979","article-title":"Comparison of four plating media for isolating Vibrio cholerae.","volume":"9","author":"Morris","year":"1979","journal-title":"J. Clin. Microbiol."},{"issue":"110","key":"B37","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-2-110","article-title":"Hospital-based surveillance of enteric parasites in Kolkata.","volume":"2","author":"Mukherjee","year":"2009","journal-title":"BMC Res. Notes"},{"key":"B38","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1086\/323458","article-title":"A large outbreak of foodborne infection attributed to Providencia alcalifaciens.","volume":"184","author":"Murata","year":"2001","journal-title":"J. Infect. Dis."},{"key":"B39","doi-asserted-by":"crossref","first-page":"4145","DOI":"10.1128\/JCM.38.11.4145-4151.2000","article-title":"Rapid method for species-specific identification of Vibrio cholerae using primers targeted to the gene of outer membrane protein OmpW.","volume":"38","author":"Nandi","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1038\/ncpgasthep1264","article-title":"Mechanisms of infectious diarrhea.","volume":"5","author":"Navaneethan","year":"2008","journal-title":"Nat. Clin. Pract. Gastroenterol. Hepatol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1089\/fpd.2007.0089","article-title":"PulseNet USA standardized pulsed-field gel electrophoresis protocol for subtyping of Vibrio parahaemolyticus.","volume":"4","author":"Parsons","year":"2007","journal-title":"Foodborne Pathog. Dis."},{"key":"B42","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.ijantimicag.2009.03.020","article-title":"Mechanism of drug resistance in a clinical isolate of Vibrio fluvialis: involvement of multiple plasmids and integrons.","volume":"34","author":"Rajpara","year":"2009","journal-title":"Int. J. Antimicrob. Agents"},{"issue":"e76200","key":"B43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0076200","article-title":"Synergistic effect of various virulence factors leading to high toxicity of environmental V. cholerae non-O1\/non-O139 isolates lacking ctx gene: comparative study with clinical strains.","volume":"8","author":"Rajpara","year":"2013","journal-title":"PLoS ONE"},{"key":"B44","author":"Sack","year":"2001","journal-title":"Antimicrobial Resistance in Shigellosis, Cholera and Campylobacteriosis."},{"key":"B45","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1099\/jmm.0.037226-0","article-title":"Clinical isolates of Vibrio fluvialis from Kolkata, India, obtained during 2006: plasmids, the qnr gene and a mutation in gyrase A as mechanisms of multidrug resistance.","volume":"61","author":"Singh","year":"2012","journal-title":"J. Med. Microbiol."},{"key":"B46","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1099\/ijs.0.63973-0","article-title":"Providencia vermicola sp. nov., isolated from infective juveniles of the entomopathogenic nematode Steinernema thermophilum.","volume":"56","author":"Somvanshi","year":"2006","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"1669","DOI":"10.1111\/j.1365-2958.1989.tb00153.x","article-title":"A novel family of potentially mobile DNA elements encoding site-specific gene-integration functions: integrons.","volume":"3","author":"Stokes","year":"1989","journal-title":"Mol. Microbiol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"2948","DOI":"10.1128\/AAC.46.9.2948-2955.2002","article-title":"Occurrence of antibiotic resistance gene cassettes aac(6\u00e2\u20ac\u2122)-Ib, dfrA5, dfrA12, and ereA2 in class I integrons in non-O1, non-O139 Vibrio cholerae strains in India.","volume":"46","author":"Thungapathra","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"B49","doi-asserted-by":"crossref","first-page":"4157","DOI":"10.1128\/jb.178.14.4157-4165.1996","article-title":"A new type of conjugative transposon encodes resistance to sulfamethoxazole, trimethoprim, and streptomycin in Vibrio cholerae O139.","volume":"178","author":"Waldor","year":"1996","journal-title":"J. Bacteriol."},{"key":"B50","author":"WHO.","year":"1987","journal-title":"Manual of Laboratory Investigation of Acute Enteric Infections."},{"key":"B51","author":"WHO.","year":"2014","journal-title":"Antimicrobial Resistance: Global Report on Surveillance 2014."},{"key":"B52","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/0378-1119(85)90120-9","article-title":"Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors.","volume":"33","author":"Yanisch-Perron","year":"1985","journal-title":"Gene"},{"key":"B53","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1099\/jmm.0.45846-0","article-title":"Importance of Providencia species as a major cause of travellers\u00e2\u20ac\u2122 diarrhea.","volume":"54","author":"Yoh","year":"2005","journal-title":"J. Med. Microbiol."},{"key":"B54","first-page":"968","article-title":"Identification of two entomopathogenic bacteria from a nematode pathogenic to the Oriental beetle, Blitopertha orientalis.","volume":"17","author":"Young-Keun","year":"2007","journal-title":"J. Microbiol. Biotech."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"deposited":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T23:56:05Z","timestamp":1651276565000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/Article\/10.3389\/fmicb.2015.00057\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,17]]},"references-count":54,"URL":"https:\/\/doi.org\/10.3389\/fmicb.2015.00057","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,17]]}}}