{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T23:02:25Z","timestamp":1791759745919,"version":"4.3.4"},"reference-count":84,"publisher":"Frontiers Media SA","funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["NSERC #342150"],"award-info":[{"award-number":["NSERC #342150"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["CIHR #93592"],"award-info":[{"award-number":["CIHR #93592"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2017.01196","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T07:14:48Z","timestamp":1498720488000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":18,"title":["Natural Killer Cell Functions during the Innate Immune Response to Pathogenic Streptococci"],"prefix":"10.3389","volume":"8","author":[{"given":"Paul","family":"Lemire","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan","family":"Galbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Thibodeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariela","family":"Segura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,6,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1038\/icb.2013.99","article-title":"TLR-mediated activation of NK cells and their role in bacterial\/viral immune responses in mammals","volume":"92","author":"Adib-Conquy","year":"2014","journal-title":"Immunol. Cell Biol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1067\/msy.2002.125311","article-title":"Natural killer cells contribute to the lethality of a murine model of Escherichia coli infection","volume":"132","author":"Badgwell","year":"2002","journal-title":"Surgery"},{"key":"B3","doi-asserted-by":"publisher","first-page":"3505","DOI":"10.1007\/s00018-011-0801-8","article-title":"NK cell activation by dendritic cells: balancing inhibitory and activating signals","volume":"68","author":"Barreira da Silva","year":"2011","journal-title":"Cell Mol. Life Sci."},{"key":"B4","doi-asserted-by":"publisher","first-page":"2115","DOI":"10.4049\/jimmunol.1601359","article-title":"CXCR3\/CXCL10 axis regulates neutrophil-NK cell cross-talk determining the severity of experimental osteoarthritis","volume":"198","author":"Benigni","year":"2017","journal-title":"J. Immunol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1751","DOI":"10.4049\/jimmunol.175.3.1751","article-title":"Relative contributions of NK and CD8 T cells to IFN-gamma mediated innate immune protection against Listeria monocytogenes","volume":"175","author":"Berg","year":"2005","journal-title":"J. Immunol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"2174","DOI":"10.4049\/jimmunol.1001486","article-title":"Primed antigen-specific CD4+ T cells are required for NK cell activation in vivo upon Leishmania major infection","volume":"185","author":"Bihl","year":"2010","journal-title":"J. Immunol."},{"key":"B7","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0167-5699(99)01467-X","article-title":"How LFA-1 binds to different ligands","volume":"20","author":"Binnerts","year":"1999","journal-title":"Immunol. Today"},{"key":"B8","doi-asserted-by":"publisher","first-page":"2578","DOI":"10.1128\/IAI.74.5.2578-2586.2006","article-title":"The NKG2D-activating receptor mediates pulmonary clearance of Pseudomonas aeruginosa","volume":"74","author":"Borchers","year":"2006","journal-title":"Infect. Immun."},{"key":"B9","doi-asserted-by":"publisher","first-page":"3267","DOI":"10.1182\/blood-2004-01-0380","article-title":"NK cell activation by dendritic cells requires the formation of a synapse leading to IL-12 polarization in dendritic cells","volume":"104","author":"Borg","year":"2004","journal-title":"Blood"},{"key":"B10","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1089\/jir.2012.0116","article-title":"Rapid IFN-gamma release from NK cells induced by a streptococcal commensal","volume":"33","author":"Bouwer","year":"2013","journal-title":"J. Interferon Cytokine Res."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1084\/jem.20102555","article-title":"Innate and cytokine-driven signals, rather than microbial antigens, dominate in NKT cell activation during microbial infection","volume":"208","author":"Brigl","year":"2011","journal-title":"J. Exp. Med."},{"key":"B12","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1128\/IAI.02427-14","article-title":"Antibody response specific to the capsular polysaccharide is impaired in Streptococcus suis serotype 2-infected animals","volume":"83","author":"Calzas","year":"2015","journal-title":"Infect. Immun."},{"key":"B13","doi-asserted-by":"publisher","first-page":"532717","DOI":"10.1155\/2015\/532717","article-title":"NK and NKT Cell depletion alters the outcome of experimental pneumococcal pneumonia: relationship with regulation of IFN-gamma production","volume":"2015","author":"Christaki","year":"2015","journal-title":"J. Immunol. Res."},{"key":"B14","doi-asserted-by":"publisher","first-page":"3096","DOI":"10.1128\/IAI.73.5.3096-3103.2005","article-title":"Structural and genetic diversity of Group B Streptococcus capsular polysaccharides","volume":"73","author":"Cieslewicz","year":"2005","journal-title":"Infect. Immun."},{"key":"B15","doi-asserted-by":"publisher","first-page":"5290604","DOI":"10.1155\/2016\/5290604","article-title":"Group B Streptococcus induces a robust IFN-gamma response by CD4(+) T cells in an in vitro and in vivo model","volume":"2016","author":"Clarke","year":"2016","journal-title":"J. Immunol. Res."},{"key":"B16","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1078\/0171-2985-00219","article-title":"Functional significance of the activation-associated receptors CD25 and CD69 on human NK cells and NKT cells","volume":"207","author":"Clausen","year":"2003","journal-title":"Immunobiology"},{"key":"B17","doi-asserted-by":"crossref","first-page":"2941","DOI":"10.1128\/IAI.64.8.2941-2944.1996","article-title":"Role of gamma interferon in a neonatal mouse model of Group B streptococcal disease","volume":"64","author":"Cusumano","year":"1996","journal-title":"Infect. Immun."},{"key":"B18","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1128\/IAI.72.1.295-300.2004","article-title":"Interleukin-18 is an essential element in host resistance to experimental Group B streptococcal disease in neonates","volume":"72","author":"Cusumano","year":"2004","journal-title":"Infect. Immun."},{"key":"B19","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1128\/IAI.64.4.1314-1320.1996","article-title":"IL-12 and TNF-alpha mediate innate production of gamma interferon by Group B Streptococcus-treated splenocytes of severe combined immunodeficiency mice","volume":"64","author":"Derrico","year":"1996","journal-title":"Infect. Immun."},{"key":"B20","doi-asserted-by":"publisher","first-page":"3901","DOI":"10.1128\/IAI.00350-08","article-title":"Comparison of the susceptibilities of C57BL\/6 and A\/J mouse strains to Streptococcus suis serotype 2 infection","volume":"76","author":"Dominguez-Punaro Mde","year":"2008","journal-title":"Infect. Immun."},{"key":"B21","doi-asserted-by":"publisher","first-page":"e23472","DOI":"10.1371\/journal.pone.0023472","article-title":"The natural cytotoxicity receptor 1 contribution to early clearance of Streptococcus pneumoniae and to NK-macrophage crosstalk","volume":"6","author":"Elhaik-Goldman","year":"2011","journal-title":"PLoS ONE"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1719","DOI":"10.1128\/IAI.00870-07","article-title":"Direct binding of human NK cell natural cytotoxicity receptor NKp44 to the surfaces of mycobacteria and other bacteria","volume":"76","author":"Esin","year":"2008","journal-title":"Infect. Immun."},{"key":"B23","doi-asserted-by":"publisher","first-page":"259","DOI":"10.2217\/fmb.11.149","article-title":"Virulence factors involved in the pathogenesis of the infection caused by the swine pathogen and zoonotic agent Streptococcus suis","volume":"7","author":"Fittipaldi","year":"2012","journal-title":"Future Microbiol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"e1005733","DOI":"10.1371\/journal.ppat.1005733","article-title":"Trypanosoma brucei co-opts NK cells to kill splenic B2 B cells","volume":"12","author":"Frenkel","year":"2016","journal-title":"PLoS Pathog."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1086\/428501","article-title":"Contribution of NK cells to the pathogenesis of septic shock induced by Streptococcus pyogenes in mice","volume":"191","author":"Goldmann","year":"2005","journal-title":"J. Infect. Dis."},{"key":"B26","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1128\/JCM.27.12.2633-2636.1989","article-title":"Description of 14 new capsular types of Streptococcus suis","volume":"27","author":"Gottschalk","year":"1989","journal-title":"J. Clin. Microbiol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"371","DOI":"10.2217\/fmb.10.2","article-title":"Streptococcus suis: a new emerging or an old neglected zoonotic pathogen?","volume":"5","author":"Gottschalk","year":"2010","journal-title":"Future Microbiol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"e45","DOI":"10.1038\/emi.2014.45","article-title":"Streptococcus suis, an important pig pathogen and emerging zoonotic agent - an update on the worldwide distribution based on serotyping and sequence typing","volume":"3","author":"Goyette-Desjardins","year":"2014","journal-title":"Emerg. Microbes Infect."},{"key":"B29","doi-asserted-by":"publisher","first-page":"590","DOI":"10.4049\/jimmunol.179.1.590","article-title":"NK cells enhance dendritic cell response against parasite antigens via NKG2D pathway","volume":"179","author":"Guan","year":"2007","journal-title":"J. Immunol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/j.chom.2013.11.004","article-title":"NK cell-mediated host defense against uropathogenic Escherichia coli is counteracted by bacterial hemolysinA-dependent killing of NK cells","volume":"14","author":"Gur","year":"2013","journal-title":"Cell Host Microbe"},{"key":"B31","doi-asserted-by":"publisher","first-page":"5172","DOI":"10.4049\/jimmunol.0903759","article-title":"Activation of naive NK cells in response to Listeria monocytogenes requires IL-18 and contact with infected dendritic cells","volume":"184","author":"Humann","year":"2010","journal-title":"J. Immunol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"401","DOI":"10.4049\/jimmunol.1002519","article-title":"NK cells promote type 1 T cell immunity through modulating the function of dendritic cells during intracellular bacterial infection","volume":"187","author":"Jiao","year":"2011","journal-title":"J. Immunol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1016\/j.micinf.2005.02.011","article-title":"Identification of a detrimental role for NK cells in pneumococcal pneumonia and sepsis in immunocompromised hosts","volume":"7","author":"Kerr","year":"2005","journal-title":"Microbes Infect."},{"key":"B34","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1038\/ni.2096","article-title":"Invariant NKT cells recognize glycolipids from pathogenic Gram-positive bacteria","volume":"12","author":"Kinjo","year":"2011","journal-title":"Nat. Immunol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1128\/IAI.01317-12","article-title":"Exacerbated type II interferon response drives hypervirulence and toxic shock by an emergent epidemic strain of Streptococcus suis","volume":"81","author":"Lachance","year":"","journal-title":"Infect. Immun."},{"key":"B36","doi-asserted-by":"publisher","first-page":"e65031","DOI":"10.1371\/journal.pone.0065031","article-title":"TLR2-independent host innate immune response against an epidemic strain of Streptococcus suis that causes a toxic shock-like syndrome in humans","volume":"8","author":"Lachance","year":"","journal-title":"PLoS ONE"},{"key":"B37","doi-asserted-by":"publisher","first-page":"4339","DOI":"10.4049\/jimmunol.0803329","article-title":"Interactions between human NK cells and macrophages in response to Salmonella infection","volume":"182","author":"Lapaque","year":"2009","journal-title":"J. Immunol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"D7","DOI":"10.1016\/j.vaccine.2013.01.009","article-title":"An overview of global Group B Streptococcus epidemiology","volume":"31","author":"Le Doare","year":"2013","journal-title":"Vaccine"},{"key":"B39","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1093\/infdis\/jir415","article-title":"Critical role for Streptococcus suis cell wall modifications and suilysin in resistance to complement-dependent killing by dendritic cells","volume":"204","author":"Lecours","year":"2011","journal-title":"J. Infect. Dis."},{"key":"B40","doi-asserted-by":"publisher","first-page":"38061","DOI":"10.1038\/srep38061","article-title":"Immune-responsiveness of CD4+ T cells during Streptococcus suis serotype 2 infection","volume":"6","author":"Lecours","year":"2016","journal-title":"Sci. Rep."},{"key":"B41","doi-asserted-by":"publisher","first-page":"e44746","DOI":"10.1371\/journal.pone.0044746","article-title":"Immune receptors involved in Streptococcus suis recognition by dendritic cells","volume":"7","author":"Lecours","year":"2012","journal-title":"PLoS ONE"},{"key":"B42","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.micpath.2013.09.006","article-title":"The NOD2 receptor does not play a major role in the pathogenesis of Group B Streptococcus in mice","volume":"65","author":"Lemire","year":"2013","journal-title":"Microb. Pathog."},{"key":"B43","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1111\/j.1462-5822.2012.01830.x","article-title":"Encapsulated Group B Streptococcus modulates dendritic cell functions via lipid rafts and clathrin-mediated endocytosis","volume":"14","author":"Lemire","year":"","journal-title":"Cell. Microbiol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1016\/j.micinf.2012.05.015","article-title":"Role of capsular polysaccharide in Group B Streptococccus interactions with dendritic cells","volume":"14","author":"Lemire","year":"","journal-title":"Microbes Infect."},{"key":"B45","doi-asserted-by":"publisher","first-page":"e113940","DOI":"10.1371\/journal.pone.0113940","article-title":"Implication of TLR- but not of NOD2-signaling pathways in dendritic cell activation by Group B Streptococcus serotypes III and V","volume":"9","author":"Lemire","year":"2014","journal-title":"PLoS ONE"},{"key":"B46","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/j.immuni.2007.03.006","article-title":"Dendritic cells prime NK cells by trans-presenting IL-15","volume":"26","author":"Lucas","year":"2007","journal-title":"Immunity"},{"key":"B47","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/82_2010_20","article-title":"Role of chemokines in the biology of NK cells","volume":"341","author":"Maghazachi","year":"2010","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"e27","DOI":"10.1017\/S1462399408000811","article-title":"Recent advances in understanding the molecular basis of Group B Streptococcus virulence","volume":"10","author":"Maisey","year":"2008","journal-title":"Expert Rev. Mol. Med."},{"key":"B49","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.1128\/IAI.65.9.3731-3735.1997","article-title":"Role of IL-12 in experimental neonatal sepsis caused by Group B streptococci","volume":"65","author":"Mancuso","year":"1997","journal-title":"Infect. Immun."},{"key":"B50","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1093\/intimm\/dxn073","article-title":"Human NK cells directly recognize Mycobacterium bovis via TLR2 and acquire the ability to kill monocyte-derived dendritic cells","volume":"20","author":"Marcenaro","year":"2008","journal-title":"Int. Immunol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"e1001191","DOI":"10.1371\/journal.ppat.1001191","article-title":"Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4","volume":"6","author":"McNeela","year":"2010","journal-title":"PLoS Pathog."},{"key":"B52","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1038\/mt.2010.75","article-title":"FimH can directly activate human and murine NK cells via TLR4","volume":"18","author":"Mian","year":"2010","journal-title":"Mol. Ther."},{"key":"B53","doi-asserted-by":"publisher","first-page":"4970","DOI":"10.4049\/jimmunol.1201687","article-title":"Inflammasome-dependent IFN-gamma drives pathogenesis in Streptococcus pneumoniae meningitis","volume":"189","author":"Mitchell","year":"2012","journal-title":"J. Immunol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1111\/j.1600-065X.2006.00450.x","article-title":"Effector and regulatory events during NK-dendritic cell interactions","volume":"214","author":"Moretta","year":"2006","journal-title":"Immunol. Rev."},{"key":"B55","doi-asserted-by":"publisher","first-page":"1213","DOI":"10.1084\/jem.20071913","article-title":"IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans-presentation","volume":"205","author":"Mortier","year":"2008","journal-title":"J. Exp. Med."},{"key":"B56","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1038\/nri2057","article-title":"Whatever turns you on: accessory-cell-dependent activation of NK cells by pathogens","volume":"7","author":"Newman","year":"2007","journal-title":"Nat. Rev. Immunol."},{"key":"B57","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1046\/j.1365-2249.1999.00922.x","article-title":"Protective role of NK1.1+ cells in experimental Staphylococcus aureus arthritis","volume":"117","author":"Nilsson","year":"1999","journal-title":"Clin. Exp. Immunol."},{"key":"B58","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0952-7915(98)80163-5","article-title":"Regulation of IFN-gamma production by IL-12 and IL-18","volume":"10","author":"Okamura","year":"1998","journal-title":"Curr. Opin. Immunol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"e43455","DOI":"10.1371\/journal.pone.0043455","article-title":"The timing of IFN-beta production affects early innate responses to Listeria monocytogenes and determines the overall outcome of lethal infection","volume":"7","author":"Pontiroli","year":"2012","journal-title":"PLoS ONE"},{"key":"B60","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1189\/jlb.71.2.173","article-title":"Role of chemokines in the biology of NK cells","volume":"71","author":"Robertson","year":"2002","journal-title":"J. Leukoc. Biol."},{"key":"B61","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1046\/j.1365-3083.1998.00305.x","article-title":"Cytokine response to Group B Streptococcus infection in mice","volume":"47","author":"Rosati","year":"1998","journal-title":"Scand. J. Immunol."},{"key":"B62","first-page":"141","article-title":"Role of the capsular polysaccharide as a virulence factor for Streptococcus suis serotype 14","volume":"79","author":"Roy","year":"2015","journal-title":"Can. J. Vet. Res."},{"key":"B63","doi-asserted-by":"publisher","first-page":"5100","DOI":"10.1128\/IAI.00438-08","article-title":"Role of NK cells in modulating dendritic cell responses to Leishmania amazonensis infection","volume":"76","author":"Sanabria","year":"2008","journal-title":"Infect. Immun."},{"key":"B64","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.it.2004.12.006","article-title":"CD69 is an immunoregulatory molecule induced following activation","volume":"26","author":"Sancho","year":"2005","journal-title":"Trends Immunol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"138","DOI":"10.4049\/jimmunol.172.1.138","article-title":"APC-independent activation of NK cells by the TLR3 agonist double-stranded RNA","volume":"172","author":"Schmidt","year":"2004","journal-title":"J. Immunol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1139\/w2012-003","article-title":"Fisher scientific award lecture - the capsular polysaccharides of Group B Streptococcus and Streptococcus suis differently modulate bacterial interactions with dendritic cells","volume":"58","author":"Segura","year":"2012","journal-title":"Can. J. Microbiol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1111\/j.1574-695X.1998.tb01165.x","article-title":"Streptococcus suis and Group B Streptococcus differ in their interactions with murine macrophages","volume":"21","author":"Segura","year":"1998","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0378-1135(03)00030-0","article-title":"Mutagenesis of Streptococcus equi and Streptococcus suis by transposon Tn917","volume":"93","author":"Slater","year":"2003","journal-title":"Vet. Microbiol."},{"key":"B69","doi-asserted-by":"publisher","first-page":"5558","DOI":"10.4049\/jimmunol.180.8.5558","article-title":"NK cells play a critical protective role in host defense against acute extracellular Staphylococcus aureus bacterial infection in the lung","volume":"180","author":"Small","year":"2008","journal-title":"J. Immunol."},{"key":"B70","doi-asserted-by":"publisher","first-page":"2048","DOI":"10.4049\/jimmunol.0902772","article-title":"Influenza infection leads to increased susceptibility to subsequent bacterial superinfection by impairing NK cell responses in the lung","volume":"184","author":"Small","year":"2010","journal-title":"J. Immunol."},{"key":"B71","doi-asserted-by":"publisher","first-page":"270","DOI":"10.2119\/molmed.2011.00201","article-title":"NK cells in antibacterial innate immunity: angels or devils?","volume":"18","author":"Souza-Fonseca-Guimaraes","year":"2012","journal-title":"Mol. Med."},{"key":"B72","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1128\/IAI.61.1.227-235.1993","article-title":"Cytokine appearance and effects of anti-TNF-alpha antibodies in a neonatal rat model of Group B streptococcal infection","volume":"61","author":"Teti","year":"1993","journal-title":"Infect. Immun."},{"key":"B73","doi-asserted-by":"publisher","first-page":"13950","DOI":"10.1073\/pnas.0506758102","article-title":"Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial \u201cpan-genome\u201d","volume":"102","author":"Tettelin","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B74","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1189\/jlb.0105051","article-title":"Flagellin enhances NK cell proliferation and activation directly and through dendritic cell-NK cell interactions","volume":"78","author":"Tsujimoto","year":"2005","journal-title":"J. Leukoc. Biol."},{"key":"B75","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1139\/bcb-2012-0036","article-title":"Structure determination of Streptococcus suis serotype 14 capsular polysaccharide","volume":"91","author":"Van Calsteren","year":"2013","journal-title":"Biochem. Cell Biol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1139\/o09-170","article-title":"Structure determination of Streptococcus suis serotype 2 capsular polysaccharide","volume":"88","author":"Van Calsteren","year":"2010","journal-title":"Biochem. Cell Biol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1097\/SHK.0b013e3181dc0977","article-title":"Early assessment of leukocyte alterations at diagnosis of septic shock","volume":"34","author":"Venet","year":"2010","journal-title":"Shock"},{"key":"B78","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1111\/j.1600-065X.2008.00673.x","article-title":"Induction and termination of inflammatory signaling in Group B streptococcal sepsis","volume":"225","author":"Wennekamp","year":"2008","journal-title":"Immunol. Rev."},{"key":"B79","doi-asserted-by":"publisher","first-page":"5481","DOI":"10.4049\/jimmunol.181.8.5481","article-title":"NKG2D is critical for NK cell activation in host defense against Pseudomonas aeruginosa respiratory infection","volume":"181","author":"Wesselkamper","year":"2008","journal-title":"J. Immunol."},{"key":"B80","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0022-3476(86)80761-2","article-title":"Immunologic basis for increased susceptibility of the neonate to infection","volume":"108","author":"Wilson","year":"1986","journal-title":"J. Pediatr."},{"key":"B81","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1086\/594370","article-title":"Clinical, experimental, and genomic differences between intermediately pathogenic, highly pathogenic, and epidemic Streptococcus suis","volume":"199","author":"Ye","year":"2009","journal-title":"J. Infect. Dis."},{"key":"B82","doi-asserted-by":"publisher","first-page":"e99486","DOI":"10.1371\/journal.pone.0099486","article-title":"Effects of novel isoform-selective phosphoinositide 3-kinase inhibitors on NK cell function","volume":"9","author":"Yea","year":"2014","journal-title":"PLoS ONE"},{"key":"B83","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1128\/IAI.73.3.1482-1490.2005","article-title":"NK cells and Helicobacter pylori infection: bacterial antigens and IL-12 act synergistically to induce gamma interferon production","volume":"73","author":"Yun","year":"2005","journal-title":"Infect. Immun."},{"key":"B84","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1016\/j.celrep.2013.08.021","article-title":"IL-15 cis presentation is required for optimal NK cell activation in lipopolysaccharide-mediated inflammatory conditions","volume":"4","author":"Zanoni","year":"2013","journal-title":"Cell Rep."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fmicb.2017.01196\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T06:16:49Z","timestamp":1692857809000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fmicb.2017.01196\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,29]]},"references-count":84,"alternative-id":["10.3389\/fmicb.2017.01196"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2017.01196","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,29]]},"article-number":"1196"}}