{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:52:18Z","timestamp":1790725938233,"version":"4.1.0"},"reference-count":73,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2018.00726","type":"journal-article","created":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T00:27:47Z","timestamp":1523492867000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":164,"title":["Candida auris: Disinfectants and Implications for Infection Control"],"prefix":"10.3389","volume":"9","author":[{"given":"Tsun S. N.","family":"Ku","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla J.","family":"Walraven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel A.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,4,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1111\/myc.12699","article-title":"In vitro efficacy of disinfectants utilised for skin decolonisation and environmental decontamination during a hospital outbreak with Candida auris.","volume":"60","author":"Abdolrasouli","year":"2017","journal-title":"Mycoses"},{"key":"B2","doi-asserted-by":"publisher","first-page":"e65","DOI":"10.1155\/2013\/929717","article-title":"Ten-year review of candidemia in a Canadian tertiary care centre: predominance of non-albicans Candida species.","volume":"24","author":"Al-Rawahi","year":"2013","journal-title":"Can. J. Infect. Dis. Med. Microbiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1111\/tid.12613","article-title":"The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).","volume":"18","author":"Andes","year":"2016","journal-title":"Transpl. Infect. Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1111\/myc.12709","article-title":"Isolation of Candida auris from 9 patients in Central America: importance of accurate diagnosis and susceptibility testing.","volume":"61","author":"Ara\u00faz","year":"2018","journal-title":"Mycoses"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00485-17","article-title":"Comparison of EUCAST and CLSI reference microdilution MICs of eight antifungal compounds for Candida auris and associated tentative epidemiological cutoff values.","volume":"61","author":"Arendrup","year":"2017","journal-title":"Antimicrob. Agents Chemother."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1093\/cid\/cix460","article-title":"Donor-derived transmission of Candida auris during lung transplantation.","volume":"65","author":"Azar","year":"2017","journal-title":"Clin. Infect. Dis."},{"key":"B7","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3201\/eid2302.161486","article-title":"Multidrug-resistant Candida haemulonii and C. auris, Tel Aviv, Israel.","volume":"23","author":"Ben-Ami","year":"2017","journal-title":"Emerg. Infect. Dis."},{"key":"B8","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1038\/nrg948","article-title":"Candida albicans: a molecular revolution built on lessons from budding yeast.","volume":"3","author":"Berman","year":"2002","journal-title":"Nat. Rev. Genet."},{"key":"B9","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/j.jhin.2017.09.009","article-title":"Controlling a possible outbreak of Candida auris infection: lessons learnt from multiple interventions.","volume":"97","author":"Biswal","year":"2017","journal-title":"J. Hosp. Infect."},{"key":"B10","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.jhin.2015.12.019","article-title":"Varying activity of chlorhexidine-based disinfectants against Klebsiella pneumoniae clinical isolates and adapted strains.","volume":"93","author":"Bock","year":"2016","journal-title":"J. Hosp. Infect."},{"key":"B11","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1093\/mmy\/myw147","article-title":"Isolates of the emerging pathogen Candida auris present in the UK have several geographic origins.","volume":"55","author":"Borman","year":"2017","journal-title":"Med. Mycol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1017\/ice.2017.239","article-title":"Relative resistance of the emerging fungal pathogen Candida auris and other Candida species to killing by ultraviolet light.","volume":"39","author":"Cadnum","year":"","journal-title":"Infect. Control Hosp. Epidemiol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.1017\/ice.2017.162","article-title":"Effectiveness of disinfectants against Candida auris and other Candida species.","volume":"38","author":"Cadnum","year":"","journal-title":"Infect. Control Hosp. Epidemiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/j.jinf.2016.07.008","article-title":"First report of Candida auris in America: clinical and microbiological aspects of 18 episodes of candidemia.","volume":"73","author":"Calvo","year":"2016","journal-title":"J. Infect."},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.MB-0020-2015","article-title":"Candida biofilms: development, architecture, and resistance.","volume":"3","author":"Chandra","year":"2015","journal-title":"Microbiol. Spectr."},{"key":"B16","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1111\/myc.12617","article-title":"Otomastoiditis caused by Candida auris: case report and literature review.","volume":"60","author":"Choi","year":"2017","journal-title":"Mycoses"},{"key":"B17","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1007\/s10096-013-2027-1","article-title":"Multidrug-resistant endemic clonal strain of Candida auris in India.","volume":"33","author":"Chowdhary","year":"2014","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.3201\/eid1910.130393","article-title":"New clonal strain of Candida auris, Delhi, India.","volume":"19","author":"Chowdhary","year":"2013","journal-title":"Emerg. Infect. Dis."},{"key":"B19","article-title":"Performance Standards for Antifungal Susceptibility Testing of Yeasts, 1st Edn.","year":"2017","journal-title":"CLSI Supplement M60."},{"key":"B20","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1086\/322972","article-title":"Biofilm formation: a clinically relevant microbiological process.","volume":"33","author":"Donlan","year":"2001","journal-title":"Clin. Infect. Dis."},{"key":"B21","doi-asserted-by":"publisher","first-page":"S12","DOI":"10.1016\/j.ajic.2012.12.010","article-title":"Does improving surface cleaning and disinfection reduce health care-associated infections?","author":"Donskey","year":"2013","journal-title":"Am. J. Infect. Control"},{"key":"B22","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1086\/520192","article-title":"Nosocomial bloodstream infections in United States hospitals: a three-year analysis.","volume":"29","author":"Edmond","year":"1999","journal-title":"Clin. Infect. Dis."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.3201\/eid2106.150270","article-title":"Candida auris candidemia in Kuwait, 2014.","volume":"21","author":"Emara","year":"2015","journal-title":"Emerg. Infect. Dis."},{"key":"B24","year":"2018","journal-title":"Antifungal Agents Breakpoint Tables for Interpretation of MICs. European Committee on Antimicrobial Susceptibility Testing 2018."},{"key":"B25","doi-asserted-by":"publisher","first-page":"e954","DOI":"10.1016\/j.ijid.2010.04.006","article-title":"Relative frequency of albicans and the various non-albicans Candida spp among candidemia isolates from inpatients in various parts of the world: a systematic review.","volume":"14","author":"Falagas","year":"2010","journal-title":"Int. J. Infect. Dis."},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002585","article-title":"Fungal Biofilms.","volume":"8","author":"Fanning","year":"2012","journal-title":"PLoS Pathog."},{"key":"B27","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/j.jdent.2012.04.003","article-title":"The antifungal properties of chlorhexidine digluconate and cetylpyrinidinium chloride on oral Candida.","volume":"40","author":"Fathilah","year":"2012","journal-title":"J. Dent."},{"key":"B28","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1128\/CMR.13.1.122-143.2000","article-title":"Potential role of phospholipases in virulence and fungal pathogenesis.","volume":"13","author":"Ghannoum","year":"2000","journal-title":"Clin. Microbiol. Rev."},{"key":"B29","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1080\/mmy.40.2.201.208","article-title":"Fungicidal activities of commonly used disinfectants and antifungal pharmaceutical spray preparations against clinical strains of Aspergillus and Candida species.","volume":"40","author":"Gupta","year":"2002","journal-title":"Med. Mycol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.jmii.2013.08.017","article-title":"Changing epidemiology of candidemia in a medical center in middle Taiwan.","volume":"48","author":"Hii","year":"2015","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"B31","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/0195-6701(91)90177-A","article-title":"Efficacy of mupirocin nasal ointment in eradicating Staphylococcus aureus nasal carriage in chronic haemodialysis patients.","volume":"17","author":"Holton","year":"1991","journal-title":"J. Hosp. Infect."},{"key":"B32","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1016\/j.arth.2012.01.010","article-title":"The persistence of Staphylococcus aureus decolonization after mupirocin and topical chlorhexidine: implications for patients requiring multiple or delayed procedures.","volume":"27","author":"Immerman","year":"2012","journal-title":"J. Arthroplasty"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00029-17","article-title":"Candida auris: a review of the literature.","volume":"31","author":"Jeffery-Smith","year":"2018","journal-title":"Clin. Microbiol. Rev."},{"key":"B34","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1128\/JCM.00367-15","article-title":"Multidrug-resistant Candida auris misidentified as Candida haemulonii: characterization by matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry and DNA sequencing and its antifungal susceptibility profile variability by Vitek 2, CLSI broth microdilution, and Etest method.","volume":"53","author":"Kathuria","year":"2015","journal-title":"J. Clin. Microbiol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.jhin.2017.11.015","article-title":"Surface disinfection challenges for Candida auris: an in vitro study.","volume":"98","author":"Kean","year":"2018","journal-title":"J. Hosp. Infect."},{"key":"B36","doi-asserted-by":"publisher","first-page":"2445","DOI":"10.1128\/JCM.00630-17","article-title":"Rapid and accurate molecular identification of the emerging multidrug-resistant pathogen Candida auris.","volume":"55","author":"Kordalewska","year":"2017","journal-title":"J. Clin. Microbiol."},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02396-16","article-title":"The emerging pathogen Candida auris: growth phenotype, virulence factors, activity of antifungals, and effect of SCY-078, a novel glucan synthesis inhibitor, on growth morphology and biofilm formation.","volume":"61","author":"Larkin","year":"2017","journal-title":"Antimicrob. Agents Chemother."},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01223-17","article-title":"Development and validation of a real-time PCR assay for rapid detection of Candida auris from surveillance samples.","volume":"24","author":"Leach","year":"2018","journal-title":"J. Clin. Microbiol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"3139","DOI":"10.1128\/JCM.00319-11","article-title":"First three reported cases of nosocomial fungemia caused by Candida auris.","volume":"49","author":"Lee","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.jhin.2011.09.014","article-title":"Biocide resistance of Candida and Escherichia coli biofilms is associated with higher antioxidative capacities.","volume":"81","author":"Leung","year":"2012","journal-title":"J. Hosp. Infect."},{"key":"B41","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1146\/annurev.micro.112408.134306","article-title":"Persister cells.","volume":"64","author":"Lewis","year":"2010","journal-title":"Annu. Rev. Microbiol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.jhin.2006.06.028","article-title":"Bacterial biofilms within the clinical setting: what healthcare professionals should know.","volume":"64","author":"Lindsay","year":"2006","journal-title":"J. Hosp. Infect."},{"key":"B43","doi-asserted-by":"publisher","first-page":"e18","DOI":"10.1093\/cid\/cir034","article-title":"Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children.","volume":"52","author":"Liu","year":"2011","journal-title":"Clin. Infect. Dis."},{"key":"B44","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1093\/cid\/ciw691","article-title":"Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses.","volume":"15","author":"Lockhart","year":"2017","journal-title":"Clin. Infect. Dis."},{"key":"B45","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.3201\/eid2007.131765","article-title":"Candida auris\u2013associated candidemia, South Africa.","volume":"20","author":"Magobo","year":"2014","journal-title":"Emerg. Infect. Dis."},{"key":"B46","first-page":"661","article-title":"Candidemia in intensive care unit: a nationwide prospective observational survey (GISIA-3 study) and review of the European literature from 2000 through 2013.","volume":"18","author":"Montagna","year":"2014","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"B47","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.jhin.2017.08.019","article-title":"Yeasticidal activity of chemical disinfectants and antiseptics against Candida auris.","volume":"97","author":"Moore","year":"2017","journal-title":"J. Hosp. Infect."},{"key":"B48","doi-asserted-by":"publisher","first-page":"162","DOI":"10.3201\/eid2301.161497","article-title":"Invasive infections with multidrug-resistant yeast Candida auris, Colombia.","volume":"23","author":"Morales-L\u00f3pez","year":"2017","journal-title":"Emerg. Infect. Dis."},{"key":"B49","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1080\/21505594.2015.1012981","article-title":"Candida albicans-epithelial interactions and pathogenicity mechanisms: scratching the surface.","volume":"19","author":"Moyes","year":"2015","journal-title":"Virulence"},{"key":"B50","first-page":"109","article-title":"Comparison of antifungal activity of 2% chlorhexidine, calcium hydroxide, and nanosilver gels against Candida albicans.","volume":"12","author":"Mozayeni","year":"2015","journal-title":"J. Dent."},{"key":"B51","year":"2002","journal-title":"Reference Method for Broth Dilution Antifungal Susceptibility of Yeasts; Approved Standard\u20132nd Edn."},{"key":"B52","doi-asserted-by":"publisher","first-page":"3411","DOI":"10.1128\/AAC.01656-07","article-title":"Reduced biocide susceptibility in Candida albicans biofilms.","volume":"52","author":"Nett","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"B53","doi-asserted-by":"publisher","first-page":"98","DOI":"10.3109\/13693786.2010.493563","article-title":"Biofilm formation and genotyping of Candida haemulonii, Candida pseudohaemulonii, and a proposed new species (Candida auris) isolates from Korea.","volume":"49","author":"Oh","year":"2011","journal-title":"Med. Mycol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1128\/AAC.01079-10","article-title":"Candida bloodstream infections: comparison of species distributions and antifungal resistance patterns in community-onset and nosocomial isolates in the SENTRY Antimicrobial Surveillance Program, 2008-2009.","volume":"55","author":"Pfaller","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"B55","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1017\/ice.2017.127","article-title":"Environmental surfaces in healthcare facilities are a potential source for transmission of Candida auris and other Candida species.","volume":"38","author":"Piedrahita","year":"2017","journal-title":"Infect. Control Hosp. Epidemiol."},{"key":"B56","doi-asserted-by":"publisher","first-page":"1494","DOI":"10.1038\/nport.2008.141","article-title":"A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing.","volume":"3","author":"Pierce","year":"2008","journal-title":"Nat. Protoc."},{"key":"B57","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.riam.2016.11.002","article-title":"Nosocomial fungemia by Candida auris: first four reported cases in continental Europe.","volume":"34","author":"Ruiz Gait\u00e1n","year":"2017","journal-title":"Rev Iberoam Micol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.ijantimicag.2012.08.014","article-title":"Chlorhexidine is a highly effective topical broad-spectrum agent against Candida spp.","volume":"41","author":"Salim","year":"2013","journal-title":"Int. J. Antimicrob. Agents"},{"key":"B59","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1111\/j.1348-0421.2008.00083.x","article-title":"Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital.","volume":"53","author":"Satoh","year":"2009","journal-title":"Microbiol. Immunol."},{"key":"B60","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1128\/EC.2.5.1053-1060.2003","article-title":"Engineered control of cell morphology in vivo reveals distinct roles for yeast and filamentous forms of Candida albicans during Infection.","volume":"2","author":"Saville","year":"2003","journal-title":"Eukaryot. Cell"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-016-0132-5","article-title":"First hospital outbreak of the globally emerging Candida auris in a European hospital.","volume":"5","author":"Schelenz","year":"2016","journal-title":"Antimicrob. Resist. Infect. Control"},{"key":"B62","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1128\/CMR.00049-15","article-title":"Decolonization in prevention of health care-associated infections.","volume":"29","author":"Septimus","year":"2016","journal-title":"Clin. Microbiol. Rev."},{"key":"B63","doi-asserted-by":"publisher","first-page":"328","DOI":"10.3201\/eid2302.161320","article-title":"Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris.","volume":"23","author":"Sherry","year":"2017","journal-title":"Emerg. Infect. Dis."},{"key":"B64","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1086\/501564","article-title":"Comparative in vitro activity of antiseptics and disinfectants versus clinical isolates of Candida species.","volume":"20","author":"Silverman","year":"1999","journal-title":"Infect. Control Hosp. Epidemiol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1099\/jmm.0.47668-0","article-title":"Efficacy of common hospital biocides with biofilms of multi-drug resistant clinical isolates.","volume":"57","author":"Smith","year":"2008","journal-title":"J. Med. Microbiol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.ijantimicag.2008.08.029","article-title":"Comparison of biofilm-associated cell survival following in vitro exposure of meticillin-resistant Staphylococcus aureus biofilms to the antibiotics clindamycin, daptomycin, linezolid, tigecycline and vancomycin.","volume":"33","author":"Smith","year":"2009","journal-title":"Int. J. Antimicrob. Agents"},{"key":"B67","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3201\/eid2301.161198","article-title":"Epidemiology of hospitalizations associated with invasive candidiasis, United States, 2002\u20132012.","volume":"23","author":"Strollo","year":"2016","journal-title":"Emerg. Infect. Dis."},{"key":"B68","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.15585\/mmwr.mm6544e1","article-title":"Investigation of the first seven reported cases of Candida auris, a globally emerging invasive, multidrug-resistant fungus - United States, May 2013-August 2016.","volume":"11","author":"Vallabhaneni","year":"2016","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"B69","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.jhin.2009.10.017","article-title":"Susceptibility of Candida albicans filamentation-defective mutants to clinical biocides.","volume":"74","author":"Watamoto","year":"2010","journal-title":"J. Hosp. Infect."},{"key":"B70","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1097\/QCO.0b013e3283630f04","article-title":"The role of the surface environment in healthcare-associated infections.","volume":"26","author":"Weber","year":"2013","journal-title":"Curr. Opin. Infect. Dis."},{"key":"B71","doi-asserted-by":"publisher","first-page":"2996","DOI":"10.1128\/JCM.00921-17","article-title":"Survival, persistence, and isolation of the emerging multidrug-resistant pathogenic yeast Candida auris on a plastic health care surface.","volume":"55","author":"Welsh","year":"2017","journal-title":"J. Clin. Microbiol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1086\/421946","article-title":"Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study.","volume":"39","author":"Wisplinghoff","year":"2004","journal-title":"Clin. Infect. Dis."},{"key":"B73","doi-asserted-by":"publisher","first-page":"633","DOI":"10.3109\/00365548.2014.922694","article-title":"Hand carriage of Candida occurs at lesser rates in hospital personnel who use antimicrobial hand disinfectant.","volume":"46","author":"Yildirim","year":"2014","journal-title":"Scand. J. Infect. Dis."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fmicb.2018.00726\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,4,12]],"date-time":"2018-04-12T00:27:47Z","timestamp":1523492867000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fmicb.2018.00726\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,12]]},"references-count":73,"alternative-id":["10.3389\/fmicb.2018.00726"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2018.00726","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,12]]},"article-number":"726"}}