{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T05:42:36Z","timestamp":1792474956951,"version":"4.5.0"},"reference-count":165,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T00:00:00Z","timestamp":1531180800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2018.01459","type":"journal-article","created":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T00:19:55Z","timestamp":1531181995000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":618,"title":["The Gut Microbiome as a Major Regulator of the Gut-Skin Axis"],"prefix":"10.3389","volume":"9","author":[{"given":"Iman","family":"Salem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Ramser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Isham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud A.","family":"Ghannoum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,7,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.22074\/cellj.2016.3980","article-title":"Epidermal differentiation complex: a review on its epigenetic regulation and potential drug targets.","volume":"18","author":"Abhishek","year":"2016","journal-title":"Cell J."},{"key":"B2","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1038\/jid.2013.334","article-title":"Propionibacterium acnes induces an IL-17 response in acne vulgaris that is regulated by vitamin A and vitamin D.","volume":"134","author":"Agak","year":"2014","journal-title":"J. Invest. Dermatol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1111\/bjd.14409","article-title":"Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin-like growth factor-1 in patients with acne vulgaris and their relationship with diet.","volume":"174","author":"Agamia","year":"2016","journal-title":"Br. J. Dermatol."},{"key":"B165","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1159\/000323305","article-title":"\u201cThe role of regulatory T cells in atopic dermatitis,\u201d","author":"Agrawal","year":"2011","journal-title":"Pathogenesis andManagement of Atopic Dermatitis"},{"key":"B4","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1111\/j.1600-0625.2009.01060.x","article-title":"Is there a \u2018gut\u2013brain\u2013skin axis\u2019?","volume":"19","author":"Arck","year":"2010","journal-title":"Exp. Dermatol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"2072","DOI":"10.3168\/jds.S0022-0302(06)72275-5","article-title":"Short communication: effects of Lactobacillus helveticus-fermented milk on the differentiation of cultured normal human epidermal keratinocytes.","volume":"89","author":"Baba","year":"2006","journal-title":"J. Dairy Sci."},{"key":"B6","author":"Baba","year":"2012"},{"key":"B7","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1271\/bbb.90370","article-title":"Oral intake of Lactobacillus helveticus-fermented milk whey decreased transepidermal water loss and prevented the onset of sodium dodecylsulfate-induced dermatitis in mice.","volume":"74","author":"Baba","year":"2010","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"B8","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1007\/s11882-013-0382-8","article-title":"The relationship between advances in understanding the microbiome and the maturing hygiene hypothesis.","volume":"13","author":"Bendiks","year":"2013","journal-title":"Curr. Allergy Asthma Rep."},{"key":"B9","doi-asserted-by":"publisher","first-page":"129","DOI":"10.3920\/BM2013.0014","article-title":"Immune modulation property of Lactobacillus paracasei NCC2461 (ST11) strain and impact on skin defences.","volume":"5","author":"Benyacoub","year":"2014","journal-title":"Benef. Microbes"},{"key":"B10","article-title":"\u201cThe effects of inflammation, infection and antibiotics on the microbiota-gut-brain axis,\u201d in","author":"Bercik","year":"2014","journal-title":"Microbial Endocrinology: the Microbiota-Gut-Brain Axis in Health and Disease. Advances in Experimental Medicine and Biology"},{"key":"B11","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.jaci.2013.07.032","article-title":"Probiotic milk consumption in pregnancy and infancy and subsequent childhood allergic diseases.","volume":"133","author":"Bertelsen","year":"2014","journal-title":"J. Allergy Clin. Immunol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1111\/bjd.12149","article-title":"Epidemiology of acne vulgaris.","volume":"168","author":"Bhate","year":"2013","journal-title":"Br. J. Dermatol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"S164","DOI":"10.1111\/j.1753-4887.2009.00237.x","article-title":"Composition and function of the human-associated microbiota.","author":"Bik","year":"2009","journal-title":"Nutr. Rev."},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1186\/s13223-016-0158-5","article-title":"Genetic and epigenetic studies of atopic dermatitis.","volume":"12","author":"Bin","year":"2016","journal-title":"Allergy Asthma Clin. Immunol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1177\/1757913916650225","article-title":"Time to abandon the hygiene hypothesis: new perspectives on allergic disease, the human microbiome, infectious disease prevention and the role of targeted hygiene.","volume":"136","author":"Bloomfield","year":"2016","journal-title":"Perspect Public Health"},{"key":"B16","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1007\/s00403-014-1477-3","article-title":"Isotretinoin therapy changes the expression of antimicrobial peptides in acne vulgaris.","volume":"306","author":"Borovaya","year":"2014","journal-title":"Arch. Dermatol. Res."},{"key":"B17","doi-asserted-by":"publisher","first-page":"185","DOI":"10.3920\/BM2012.0060","article-title":"Acne vulgaris, probiotics and the gut-brain-skin axis: from anecdote to translational medicine.","volume":"5","author":"Bowe","year":"2014","journal-title":"Benef. Microbes"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1186\/1757-4749-3-1","article-title":"Acne vulgaris, probiotics and the gut-brain-skin axis-back to the future?","volume":"3","author":"Bowe","year":"2011","journal-title":"Gut Pathog."},{"key":"B19","first-page":"742","article-title":"Acne vulgaris: the role of oxidative stress and the potential therapeutic value of local and systemic antioxidants.","volume":"11","author":"Bowe","year":"2012","journal-title":"J. Drugs Dermatol."},{"key":"B20","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4419-7967-4_8","article-title":"\u201cProbiotics and skin,\u201d in","author":"Boyle","year":"2011","journal-title":"Nutrition and Skin"},{"key":"B21","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1159\/000066245","article-title":"Neurogenic modifications induced by substance P in an organ culture of human skin.","volume":"12","author":"Branchet-Gumila","year":"1999","journal-title":"Skin Pharmacol. Physiol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"2978","DOI":"10.3748\/wjg.v16.i24.2978","article-title":"Small intestinal bacterial overgrowth syndrome.","volume":"16","author":"Bures","year":"2010","journal-title":"World J. Gastroenterol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1136\/gut.2008.165886","article-title":"Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability.","volume":"58","author":"Cani","year":"2009","journal-title":"Gut"},{"key":"B24","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.exger.2017.01.009","article-title":"Molecular mechanisms of UVB-induced senescence of dermal fibroblasts and its relevance for photoaging of the human skin.","volume":"94","author":"Cavinato","year":"2017","journal-title":"Exp. Gerontol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1001\/jamapediatrics.2015.3943","article-title":"Synbiotics for prevention and treatment of atopic dermatitis: a meta-analysis of randomized clinical trials.","volume":"170","author":"Chang","year":"2016","journal-title":"JAMA Pediatr."},{"key":"B26","doi-asserted-by":"publisher","first-page":"2520","DOI":"10.1002\/eji.200425139","article-title":"Lactobacillus casei reduces CD8 + T cell-mediated skin inflammation.","volume":"34","author":"Chapat","year":"2004","journal-title":"Eur. J. Immunol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"3344","DOI":"10.3892\/mmr.2015.3212","article-title":"Astragaloside IV controls collagen reduction in photoaging skin by improving transforming growth factor-\u03b2\/Smad signaling suppression and inhibiting matrix metalloproteinase-1.","volume":"11","author":"Chen","year":"2015","journal-title":"Mol. Med. Rep."},{"key":"B28","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/j.jfda.2016.06.003","article-title":"Lactobacillus pentosus GMNL-77 inhibits skin lesions in imiquimod-induced psoriasis-like mice.","volume":"25","author":"Chen","year":"2017","journal-title":"J. Food Drug Anal."},{"key":"B29","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/nm.2087","article-title":"Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity.","volume":"16","author":"Clarke","year":"2010","journal-title":"Nat. Med."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1016\/j.cell.2012.01.035","article-title":"The impact of the gut microbiota on human health: an integrative view.","volume":"148","author":"Clemente","year":"2012","journal-title":"Cell"},{"key":"B31","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-319-18227-8_2","article-title":"\u201cPathogenesis of psoriasis and psoriatic arthritis,\u201d in","author":"Coates","year":"2016","journal-title":"Handbook of Psoriasis and Psoriatic Arthritis"},{"key":"B32","doi-asserted-by":"publisher","first-page":"4163","DOI":"10.1128\/IAI.00188-08","article-title":"The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis.","volume":"76","author":"Cosseau","year":"2008","journal-title":"Infect. Immun."},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f2634","article-title":"Acne vulgaris.","volume":"346","author":"Dawson","year":"2013","journal-title":"BMJ"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-11-86","article-title":"The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains.","volume":"11","author":"Dawson","year":"2011","journal-title":"BMC Microbiol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"125","DOI":"10.5021\/ad.2009.21.2.125","article-title":"Psychosocial aspects of acne vulgaris: a community-based study with Korean adolescents.","volume":"21","author":"Do","year":"2009","journal-title":"Ann. Dermatol."},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-69511-0_5","article-title":"\u201cCD1 expression on antigen-presenting cells,\u201d in","author":"Dougan","year":"2007","journal-title":"T Cell Activation by CD1 and Lipid Antigens. Current Topics in Microbiology and Immunology"},{"key":"B37","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1111\/exd.13296","article-title":"Skin microbiome and acne vulgaris: staphylococcus, a new actor in acne.","volume":"26","author":"Dreno","year":"2017","journal-title":"Exp. Dermatol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.dsi.2015.07.002","article-title":"Evaluation of anxiety, depression, and quality of life in patients with acne vulgaris, and quality of life in their families.","volume":"34","author":"Duman","year":"2016","journal-title":"DSI"},{"key":"B39","doi-asserted-by":"publisher","first-page":"575","DOI":"10.2332\/allergolint.13-OA-0683","article-title":"Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota.","volume":"63","author":"Enomoto","year":"2014","journal-title":"Allergol. Int."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11926-013-0407-2","article-title":"The microbiome and psoriatic arthritis.","volume":"16","author":"Eppinga","year":"2014","journal-title":"Curr. Rheumatol. Rep."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1093\/ecco-jcc\/jjw070","article-title":"Similar depletion of protective Faecalibacterium prausnitzii in psoriasis and inflammatory bowel disease, but not in hidradenitis suppurativa.","volume":"10","author":"Eppinga","year":"2016","journal-title":"J. Crohns. Colitis"},{"key":"B42","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1038\/nature10228","article-title":"Control of TH17 cells occurs in the small intestine.","volume":"475","author":"Esplugues","year":"2011","journal-title":"Nature"},{"key":"B43","doi-asserted-by":"publisher","first-page":"625","DOI":"10.3920\/BM2016.0089","article-title":"Supplementation with Lactobacillus rhamnosus SP1 normalises skin expression of genes implicated in insulin signalling and improves adult acne.","volume":"7","author":"Fabbrocini","year":"2016","journal-title":"Benef. Microbes"},{"key":"B44","article-title":"Are skincare Products with probiotics worth the hype?.","author":"Farris","year":"2016","journal-title":"Dermatology Times"},{"key":"B45","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1007\/s11926-007-0075-1","article-title":"Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines.","volume":"9","author":"Fitch","year":"2007","journal-title":"Curr. Rheum. Rep."},{"key":"B46","article-title":"The gut microbiota in immune-mediated inflammatory diseases.","volume":"7","author":"Forbes","year":"2015","journal-title":"Front. Microbiol."},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21081063","article-title":"Treatment modalities for acne.","volume":"21","author":"Fox","year":"2016","journal-title":"Molecules"},{"key":"B48","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1097\/MOG.0000000000000151","article-title":"Prebiotics, probiotics, synbiotics, and the immune system: experimental data and clinical evidence.","volume":"31","author":"Frei","year":"2015","journal-title":"Curr. Opin. Gastroenterol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1111\/j.1398-9995.2011.02783.x","article-title":"Microbiota and dietary interactions: an update to the hygiene hypothesis?","volume":"67","author":"Frei","year":"2012","journal-title":"Allergy"},{"key":"B50","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1038\/nri3707","article-title":"IL-23-IL-17 immune axis: discovery, mechanistic understanding, and clinical testing.","volume":"14","author":"Gaffen","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18010208","article-title":"Mesenchymal stem cells from adipose tissue in clinical applications for dermatological indications and skin aging.","volume":"18","author":"Gaur","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-03218-4_48","article-title":"\u201cCutaneous manifestations of gastrointestinal disease,\u201d in","author":"Gloster","year":"2016","journal-title":"Absolute Dermatology Review"},{"key":"B53","doi-asserted-by":"publisher","first-page":"3887","DOI":"10.1080\/10408398.2016.1189872","article-title":"An overview of the effect of probiotics and exercise on mood and associated health conditions.","volume":"57","author":"Grant","year":"2017","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"B54","doi-asserted-by":"publisher","first-page":"325","DOI":"10.4161\/gmic.25487","article-title":"Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut.","volume":"4","author":"Groeger","year":"2013","journal-title":"Gut Microbes"},{"key":"B55","doi-asserted-by":"publisher","first-page":"137","DOI":"10.3920\/BM2013.0001","article-title":"Randomised double-blind placebo-controlled study of the effect of Lactobacillus paracasei NCC 2461 on skin reactivity.","volume":"5","author":"Gu\u00e9niche","year":"2013","journal-title":"Benef. Microbes"},{"key":"B56","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1684\/ejd.2006.0023","article-title":"Supplementation with oral probiotic bacteria maintains cutaneous immune homeostasis after UV exposure.","volume":"16","author":"Gu\u00e9niche","year":"2006","journal-title":"Eur. J. Dermatol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1684\/ejd.2010.1108","article-title":"Lactobacillus paracasei CNCM I-2116 (ST11) inhibits substance P-induced skin inflammation and accelerates skin barrier function recovery in vitro.","volume":"20","author":"Gu\u00e9niche","year":"2010","journal-title":"Eur. J. Dermatol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"7420","DOI":"10.4049\/jimmunol.181.10.7420","article-title":"Low expression of the IL-23\/Th17 pathway in atopic dermatitis compared to psoriasis.","volume":"181","author":"Guttman-Yassky","year":"2008","journal-title":"J. Immunol."},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004903","article-title":"Oral probiotic control skin inflammation by acting on both effector and regulatory T cells.","volume":"4","author":"Hacini-Rachinel","year":"2009","journal-title":"PLoS One"},{"key":"B60","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.1038\/jid.2013.446","article-title":"The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions.","volume":"134","author":"Hay","year":"2014","journal-title":"J. Invest. Dermatol."},{"key":"B61","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1038\/nrgastro.2014.66","article-title":"Expert consensus document: the International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic.","volume":"11","author":"Hill","year":"2014","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"B62","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1111\/jam.12435","article-title":"Effect of heat-killed Lactobacillus brevis SBC8803 on cutaneous arterial sympathetic nerve activity, cutaneous blood flow and transepidermal water loss in rats.","volume":"116","author":"Horii","year":"2014","journal-title":"J. Appl. Microbiol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.alit.2015.09.004","article-title":"Transepidermal water loss measurement during infancy can predict the subsequent development of atopic dermatitis regardless of filaggrin mutations.","volume":"65","author":"Horimukai","year":"2016","journal-title":"Allergol. Int."},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2012.00013","article-title":"Skin manifestations of inflammatory bowel disease.","volume":"3","author":"Huang","year":"2012","journal-title":"Front. Physiol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1016\/j.jaci.2017.02.007","article-title":"The microbiome in allergic disease: current understanding and future opportunities \u2013 2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology.","volume":"139","author":"Huang","year":"2017","journal-title":"J. Allergy Clin. Immunol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00405-016-4058-6","article-title":"The possible mechanisms of the human microbiome in allergic diseases.","volume":"274","author":"Ipci","year":"2017","journal-title":"Eur. Arch. Otorhinolaryngol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"S89","DOI":"10.12788\/j.sder.2016.042","article-title":"Review of critical issues in the pathogenesis of atopic dermatitis.","volume":"35","author":"Irvine","year":"2016","journal-title":"Semin. Cutan Med. Surg."},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.15373\/22501991","article-title":"Evaluation of associated anxiety and depression in patients with acne vulgaris: a hospital based clinico-epidemiological study.","volume":"5","author":"Jena","year":"2016","journal-title":"PIJR"},{"key":"B69","doi-asserted-by":"publisher","first-page":"2331","DOI":"10.1080\/10408398.2013.834874","article-title":"Probiotic lactic acid bacteria and skin health.","volume":"56","author":"Jeong","year":"2016","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"B70","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.trsl.2016.06.010","article-title":"The infant gut bacterial microbiota and risk of pediatric asthma and allergic diseases.","volume":"179","author":"Johnson","year":"2017","journal-title":"Transl. Res."},{"key":"B71","doi-asserted-by":"publisher","first-page":"114","DOI":"10.2310\/7750.2012.12026","article-title":"Prospective, randomized, open-label trial comparing the safety, efficacy, and tolerability of an acne treatment regimen with and without a probiotic supplement and minocycline in subjects with mild to moderate acne.","volume":"17","author":"Jung","year":"2013","journal-title":"J. Cutan Med. Surg."},{"key":"B72","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1016\/j.mehy.2007.02.037","article-title":"Acne vulgaris: nutritional factors may be influencing psychological sequelae.","volume":"69","author":"Katzman","year":"2007","journal-title":"Med. Hypotheses."},{"key":"B73","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1016\/j.jaci.2014.12.013","article-title":"Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year.","volume":"135","author":"Kelleher","year":"2015","journal-title":"J. Allergy Clin. Immunol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"369","DOI":"10.3345\/kjp.2013.56.9.369","article-title":"Clinical efficacy and mechanism of probiotics in allergic diseases.","volume":"56","author":"Kim","year":"2013","journal-title":"Korean J. Pediatr."},{"key":"B75","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1111\/j.1600-0625.2012.01539.x","article-title":"A novel mouse model of atopic dermatitis with epicutaneous allergen sensitization and the effect of Lactobacillus rhamnosus.","volume":"21","author":"Kim","year":"2012","journal-title":"Exp. Dermatol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.4014\/jmb.1406.06038","article-title":"Oral administration of Lactobacillus plantarum HY7714 protects hairless mouse against ultraviolet B-induced photoaging.","volume":"24","author":"Kim","year":"2014","journal-title":"J. Microbiol. Biotechnol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"e386","DOI":"10.1111\/j.1399-3038.2009.00958.x","article-title":"Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebo-controlled trial.","volume":"21","author":"Kim","year":"2010","journal-title":"Pediatr. Allergy Immunol."},{"key":"B78","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.chom.2013.12.010","article-title":"Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE2.","volume":"15","author":"Kim","year":"2014","journal-title":"Cell Host Microbe"},{"key":"B79","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.ijwd.2015.02.001","article-title":"The effect of probiotics on immune regulation, acne, and photoaging.","volume":"1","author":"Kober","year":"2015","journal-title":"Int. J. Womens Dermatol."},{"key":"B80","doi-asserted-by":"publisher","first-page":"4195","DOI":"10.1016\/j.febslet.2014.03.019","article-title":"Relationship between gut microbiota and development of T cell associated disease.","volume":"588","author":"Kosiewicz","year":"2014","journal-title":"FEBS Lett."},{"key":"B81","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jdermsci.2009.01.002","article-title":"Pre-and probiotics for human skin.","volume":"54","author":"Krutmann","year":"2009","journal-title":"J. Dermatol. Sci."},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13466","article-title":"IL-12 protects from psoriasiform skin inflammation.","volume":"7","author":"Kulig","year":"2016","journal-title":"Nat. Commun."},{"key":"B83","doi-asserted-by":"publisher","first-page":"2160","DOI":"10.4014\/jmb.1509.09021","article-title":"Clinical evidence of effects of Lactobacillus plantarum HY7714 on skin aging: a randomized, double blind, placebo-controlled study.","volume":"25","author":"Lee","year":"2015","journal-title":"J. Microbiol. Biotechnol."},{"key":"B84","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1111\/1348-0421.12390","article-title":"Therapeutic effect of tyndallized Lactobacillus rhamnosus IDCC 3201 on atopic dermatitis mediated by down-regulation of immunoglobulin E in NC\/Nga mice.","volume":"60","author":"Lee","year":"2016","journal-title":"Microbiol. Immunol."},{"key":"B85","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1007\/s00403-008-0854-1","article-title":"Influence of substance-P on cultured sebocytes.","volume":"300","author":"Lee","year":"2008","journal-title":"Arch. Dermatol. Res."},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0053867","article-title":"Probiotic bacteria induce a \u2018glow of health\u2019.","volume":"8","author":"Levkovich","year":"2013","journal-title":"PLoS One"},{"key":"B87","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1128\/AEM.06858-11","article-title":"Cultured representatives of two major phylogroups of human colonic Faecalibacterium prausnitzii can utilize pectin, uronic acids, and host-derived substrates for growth.","volume":"78","author":"Lopez-Siles","year":"2012","journal-title":"Appl. Environ. Microbiol."},{"key":"B88","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1038\/jid.2011.375","article-title":"Regulatory T cells: banned cells for decades.","volume":"132","author":"Loser","year":"2012","journal-title":"J. Invest. Dermatol."},{"key":"B89","doi-asserted-by":"publisher","first-page":"13","DOI":"10.2147\/AHMT.S55832","article-title":"The epidemiology of acne vulgaris in late adolescence.","volume":"7","author":"Lynn","year":"2016","journal-title":"Adolesc. Health Med. Ther."},{"key":"B90","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1172\/JCI33263","article-title":"IL-22 is required for Th17 cell\u2013mediated pathology in a mouse model of psoriasis-like skin inflammation.","volume":"118","author":"Ma","year":"2008","journal-title":"J. Clin. Invest."},{"key":"B91","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1038\/nri1373","article-title":"Interactions between commensal intestinal bacteria and the immune system.","volume":"4","author":"Macpherson","year":"2004","journal-title":"Nat. Rev. Immunol."},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1186\/s41110-016-0029-3","article-title":"n-3 polyunsaturated fatty acids supplementation in psoriasis: a review.","volume":"42","author":"Mari","year":"2017","journal-title":"Nutrire"},{"key":"B93","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.1038\/nature08530","article-title":"Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.","volume":"461","author":"Maslowski","year":"2009","journal-title":"Nature"},{"key":"B94","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1016\/j.clindermatol.2016.07.004","article-title":"Nutrition and skin: kids are not just little people.","volume":"34","author":"McCusker","year":"2016","journal-title":"Clin. Dermatol."},{"key":"B95","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1097\/MCO.0b013e32833eebe5","article-title":"Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health?","volume":"13","author":"Meijer","year":"2010","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"B96","doi-asserted-by":"publisher","first-page":"17048","DOI":"10.3390\/ijms160817048","article-title":"Milk. A nutrient system of mammalian evolution promoting mTORC1-dependent translation.","volume":"16","author":"Melnik","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"B97","doi-asserted-by":"publisher","first-page":"121","DOI":"10.3920\/BM2012.0066","article-title":"Bifidobacterium fermented milk and galacto-oligosaccharides lead to improved skin health by decreasing phenols production by gut microbiota.","volume":"5","author":"Miyazaki","year":"2014","journal-title":"Benef. Microbes"},{"key":"B98","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1097\/MIB.0000000000000717","article-title":"Novel strategies for applied metagenomics.","volume":"22","author":"Moore-Connors","year":"2016","journal-title":"Inflamm. Bowel Dis."},{"key":"B99","first-page":"385","article-title":"Physiological effect of a probiotic on skin.","volume":"63","author":"Muizzuddin","year":"2012","journal-title":"J. Cosmet. Sci."},{"key":"B100","doi-asserted-by":"publisher","first-page":"1347","DOI":"10.1016\/j.jaci.2016.03.010","article-title":"Precision medicine in patients with allergic diseases: airway diseases and atopic dermatitis\u2014PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology.","volume":"137","author":"Muraro","year":"2016","journal-title":"J. Allergy Clin. Immunol."},{"key":"B101","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.clp.2011.03.008","article-title":"Cesarean versus vaginal delivery: long-term infant outcomes and the hygiene hypothesis.","volume":"38","author":"Neu","year":"2011","journal-title":"Clin. Perinatol."},{"key":"B102","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.micpath.2018.03.021","article-title":"Gut microbiota and mTOR signaling: insight on a new pathophysiological interaction.","volume":"118","author":"Noureldein","year":"2018","journal-title":"Microb. Pathog."},{"key":"B103","doi-asserted-by":"publisher","first-page":"3863","DOI":"10.3892\/etm.2016.3862","article-title":"Effects of oral intake of heat-killed Lactobacillus brevis SBC8803 (SBL88TM) on dry skin conditions: a randomized, double-blind, placebo-controlled study.","volume":"12","author":"Ogawa","year":"2016","journal-title":"Exp. Ther. Med."},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2015.00639","article-title":"The Treg\/Th17 axis: a dynamic balance regulated by the gut microbiome.","volume":"6","author":"Omenetti","year":"2015","journal-title":"Front. Immunol."},{"key":"B105","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1002\/bies.201600008","article-title":"The gut-skin axis in health and disease: a paradigm with therapeutic implications.","volume":"38","author":"O\u2019Neill","year":"2016","journal-title":"Bioessays"},{"key":"B106","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1111\/imr.12545","article-title":"The interplay between genetic and environmental factors in the pathogenesis of atopic dermatitis.","volume":"278","author":"Otsuka","year":"2017","journal-title":"Immunol. Rev."},{"key":"B107","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1038\/jid.2012.339","article-title":"Global epidemiology of psoriasis: a systematic review of incidence and prevalence.","volume":"133","author":"Parisi","year":"2013","journal-title":"J. Invest. Dermatol."},{"key":"B108","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1684\/ejd.2008.0496","article-title":"Supplementation with oral probiotic bacteria protects human cutaneous immune homeostasis after UV exposure \u2013 double blind, randomized, placebo controlled clinical trial.","volume":"18","author":"Peguet-Navarro","year":"2008","journal-title":"Eur. J. Dermatol."},{"key":"B109","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1016\/j.clinthera.2015.04.002","article-title":"Gut-microbiota-brain axis and its effect on neuropsychiatric disorders with suspected immune dysregulation.","volume":"37","author":"Petra","year":"2015","journal-title":"Clin. Ther."},{"key":"B110","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1684\/ejd.2010.1242","article-title":"Oral Lactobacillus paracasei improves skin barrier function recovery and reduces local skin inflammation.","volume":"21","author":"Philippe","year":"2011","journal-title":"Eur. J. Dermatol."},{"key":"B111","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s13555-016-0168-8","article-title":"Acne and Rosacea.","author":"Picardo","year":"2017","journal-title":"Dermatol. Ther. (Heidelb)."},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17060868","article-title":"Role of matrix metalloproteinases in photoaging and photocarcinogenesis.","volume":"17","author":"Pittayapruek","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"B113","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078898","article-title":"Microbial symbionts accelerate wound healing via the neuropeptide hormone oxytocin.","volume":"8","author":"Poutahidis","year":"2013","journal-title":"PLoS One"},{"key":"B114","doi-asserted-by":"publisher","first-page":"107","DOI":"10.15373\/22778160","article-title":"study of presence of depression in acne vulgaris patients.","volume":"5","author":"Prakash","year":"2016","journal-title":"GJRA"},{"key":"B115","first-page":"323","article-title":"The role of intestinal microbiota and the immune system.","volume":"17","author":"Purchiaroni","year":"2013","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"B116","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1111\/bjd.15379","article-title":"Age-related reduction of dermal fibroblast size up-regulates multiple matrix metalloproteinases as observed in aged human skin in vivo.","volume":"177","author":"Qin","year":"2017","journal-title":"Br. J. Dermatol."},{"key":"B117","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.1038\/jid.2012.509","article-title":"Elevated matrix metalloproteinases and collagen fragmentation in photodamaged human skin: impact of altered extracellular matrix microenvironment on dermal fibroblast function.","volume":"133","author":"Quan","year":"2013","journal-title":"J. Invest. Dermatol."},{"key":"B118","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/j.jaad.2013.11.013","article-title":"Psoriasis prevalence among adults in the United States.","volume":"70","author":"Rachakonda","year":"2014","journal-title":"J. Am. Acad. Dermatol."},{"key":"B119","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1111\/1574-6976.12075","article-title":"The first 1000 cultured species of the human gastrointestinal microbiota.","volume":"38","author":"Rajili\u0107-Stojanovi\u0107","year":"2014","journal-title":"FEMS Microbiol. Rev."},{"key":"B120","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1001\/jamadermatol.2014.5585","article-title":"Identification of bacterial DNA in the peripheral blood of patients with active psoriasis.","volume":"151","author":"Ram\u00edrez-Bosc\u00e1","year":"2015","journal-title":"JAMA Dermatol."},{"key":"B121","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1111\/bjd.13786","article-title":"Cumulative mental health consequences of acne: 23-year follow-up in a general population birth cohort study.","volume":"175","author":"Ramrakha","year":"2016","journal-title":"Br. J. Dermatol."},{"key":"B122","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00507","article-title":"Probiotics and atopic dermatitis: an overview.","volume":"7","author":"Rather","year":"2016","journal-title":"Front. Microbiol."},{"key":"B123","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1016\/j.tig.2010.06.006","article-title":"Psoriasis genetics: breaking the barrier.","volume":"26","author":"Roberson","year":"2010","journal-title":"Trends Genet."},{"key":"B124","doi-asserted-by":"publisher","first-page":"3","DOI":"10.2147\/CCID.S125438","article-title":"Efficacy of a twice-daily, 3-step, over-the-counter skincare regimen for the treatment of acne vulgaris.","volume":"10","author":"Rodan","year":"2017","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"B125","doi-asserted-by":"publisher","first-page":"464","DOI":"10.5021\/ad.2016.28.4.464","article-title":"Stressful events and serum concentration of substance P in acne patients.","volume":"28","author":"Rokowska-Waluch","year":"2016","journal-title":"Ann. Dermatol."},{"key":"B126","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s12016-011-8285-8","article-title":"Hygiene hypothesis and autoimmune diseases.","volume":"42","author":"Rook","year":"2012","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"B127","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.01085","article-title":"Regulation of lung immunity and host defense by the intestinal microbiota.","volume":"6","author":"Samuelson","year":"2015","journal-title":"Front. Microbiol."},{"key":"B128","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201600240","article-title":"Probiotics, gut microbiota, and their influence on host health and disease.","volume":"61","author":"S\u00e1nchez","year":"2017","journal-title":"Mol. Nutr. Food Res."},{"key":"B129","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1080\/10408398.2014.887055","article-title":"Probiotics, prebiotics, and microencapsulation: a review.","volume":"57","author":"Sarao","year":"2017","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"B130","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1002\/art.38892","article-title":"Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease.","volume":"67","author":"Scher","year":"2015","journal-title":"Arthritis Rheumatol."},{"key":"B131","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1016\/j.jid.2016.11.014","article-title":"The short-chain fatty acid sodium butyrate functions as a regulator of the skin immune system.","volume":"1","author":"Schwarz","year":"2017","journal-title":"J. Investig. Dermatol."},{"key":"B132","doi-asserted-by":"publisher","first-page":"479","DOI":"10.2147\/CCID.S91521","article-title":"Barrier function and microbiotic dysbiosis in atopic dermatitis.","volume":"8","author":"Seite","year":"2015","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"B133","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.10.037","article-title":"Cutaneous manifestations of gastrointestinal disease: part I.","volume":"68","author":"Shah","year":"2013","journal-title":"JAAD"},{"key":"B134","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055380","article-title":"Fermentation of Propionibacterium acnes, a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant Staphylococcus aureus.","volume":"8","author":"Shu","year":"2013","journal-title":"PLoS One"},{"key":"B135","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1016\/j.jaci.2014.08.005","article-title":"Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention.","volume":"134","author":"Simpson","year":"2014","journal-title":"J. Allergy Clin. Immunol."},{"key":"B136","doi-asserted-by":"publisher","first-page":"249","DOI":"10.12932\/AP0803","article-title":"The potential impact of gut microbiota on your health: current status and future challenges.","volume":"34","author":"Sirisinha","year":"2016","journal-title":"Asian Pac. J. Allergy Immunol."},{"key":"B137","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.micinf.2010.02.002","article-title":"The hygiene hypothesis: an evolutionary perspective.","volume":"12","author":"Sironi","year":"2010","journal-title":"Microbes Infect."},{"key":"B138","first-page":"52","article-title":"Lactobacillus for the control of acne.","volume":"59","author":"Siver","year":"1961","journal-title":"J. Med. Soc. New Jersey"},{"key":"B139","doi-asserted-by":"publisher","first-page":"16731","DOI":"10.1073\/pnas.0804812105","article-title":"Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients.","volume":"105","author":"Sokol","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B140","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1016\/j.jaci.2015.08.021","article-title":"Faecalibacterium prausnitzii subspecies\u2013level dysbiosis in the human gut microbiome underlying atopic dermatitis.","volume":"137","author":"Song","year":"2016","journal-title":"J. Allergy Clin. Immunol."},{"key":"B141","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1001\/archderm.1930.01440180008002","article-title":"The effect on the skin of emotional and nervous states: iII. Theoretical and practical consideration of a gastro-intestinal mechanism.","volume":"22","author":"Stokes","year":"1930","journal-title":"Arch. Derm. Syphilol."},{"key":"B142","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1136\/bmj.299.6710.1259","article-title":"Hay fever, hygiene, and household size.","volume":"299","author":"Strachan","year":"1989","journal-title":"BMJ"},{"key":"B143","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.jaad.2016.07.064","article-title":"Psoriasis and comorbid diseases: epidemiology.","volume":"76","author":"Takeshita","year":"2017","journal-title":"J. Am. Acad. Dermatol."},{"key":"B144","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/bjd.13462","article-title":"A global perspective on the epidemiology of acne.","author":"Tan","year":"2015","journal-title":"Br. J. Dermatol."},{"key":"B145","doi-asserted-by":"publisher","first-page":"430","DOI":"10.4161\/gmic.29796","article-title":"Effect of commensals and probiotics on visceral sensitivity and pain in irritable bowel syndrome.","volume":"5","author":"Theodorou","year":"2014","journal-title":"Gut Microbes"},{"key":"B146","doi-asserted-by":"publisher","first-page":"148","DOI":"10.4161\/gmic.1.3.11712","article-title":"Probiotics-host communication: modulation of signaling pathways in the intestine.","volume":"1","author":"Thomas","year":"2010","journal-title":"Gut Microbes"},{"key":"B147","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.10.036","article-title":"Cutaneous manifestations of gastrointestinal disease: part II.","volume":"68","author":"Thrash","year":"2013","journal-title":"JAAD"},{"key":"B148","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1097\/ACI.0b013e3282ef869e","article-title":"Interleukin-17 in inflammatory skin disorders.","volume":"7","author":"Van Beelen","year":"2007","journal-title":"Curr. Opin. Allergy Clin. Immunol."},{"key":"B149","doi-asserted-by":"publisher","first-page":"52","DOI":"10.5314\/wjd.v6.i4.52","article-title":"Skin-gut axis: the relationship between intestinal bacteria and skin health.","volume":"6","author":"Vaughn","year":"2017","journal-title":"World J. Dermatol."},{"key":"B150","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1080\/14712598.2017.1258399","article-title":"Biological therapy targeting the IL-23\/IL-17 axis in inflammatory bowel disease.","volume":"17","author":"Verstockt","year":"2016","journal-title":"Exp. Opin. Biol. Ther."},{"key":"B151","doi-asserted-by":"publisher","first-page":"326","DOI":"10.7241\/ourd.20124.71","article-title":"Pustular psoriasis responding to probiotics \u2013 A new insight.","volume":"3","author":"Vijayashankar","year":"2012","journal-title":"Our Dermatol."},{"key":"B152","first-page":"39","article-title":"Impact of the impaired intestinal microflora on the course of acne vulgaris.","volume":"79","author":"Volkova","year":"2001","journal-title":"Klin. Med. (Mosk)."},{"key":"B153","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1146\/annurev-pathol-011110-130318","article-title":"The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin.","volume":"24","author":"Weaver","year":"2013","journal-title":"Annu. Rev. Pathol."},{"key":"B154","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1016\/j.immuni.2016.02.002","article-title":"The microbiome, timing, and barrier function in the context of allergic disease.","volume":"44","author":"Wesemann","year":"2016","journal-title":"Immunity"},{"key":"B155","article-title":"\u201cSkin aging: a brief summary of characteristic changes,\u201d in","author":"Wiegand","year":"2016","journal-title":"Textbook of Aging Skin"},{"key":"B156","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1111\/j.1365-2672.2011.04981.x","article-title":"Oral administration of Lactobacillus strains from Kimchi inhibits atopic dermatitis in NC\/Nga mice.","volume":"110","author":"Won","year":"2011","journal-title":"J. Appl. Microbiol."},{"key":"B157","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1016\/j.cgh.2013.03.038","article-title":"Analysis of the human gut microbiome and association with disease.","volume":"11","author":"Wu","year":"2013","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"B158","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.jdermsci.2015.01.009","article-title":"A mouse model of skin aging: fragmentation of dermal collagen fibrils and reduced fibroblast spreading due to expression of human matrix metalloproteinase-1.","volume":"78","author":"Xia","year":"2015","journal-title":"J. Dermatol. Sci."},{"key":"B159","first-page":"94","article-title":"Acne vulgaris in the United States: a descriptive epidemiology.","volume":"86","author":"Yentzer","year":"2010","journal-title":"Cutis"},{"key":"B160","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.4014\/jmb.1306.06026","article-title":"Lactobacillus sakei lipoteichoic acid inhibits MMP-1 induced by UVA in normal dermal fibroblasts of human.","volume":"23","author":"You","year":"2013","journal-title":"J. Microbiol. Biotechnol."},{"key":"B161","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1016\/j.jaad.2015.12.037","article-title":"Guidelines of care for the management of acne vulgaris.","volume":"74","author":"Zaenglein","year":"2016","journal-title":"J. Am. Acad. Dermatol."},{"key":"B162","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1111\/j.1346-8138.2008.00523.x","article-title":"Risk factors for sebaceous gland diseases and their relationship to gastrointestinal dysfunction in Han adolescents.","volume":"35","author":"Zhang","year":"2008","journal-title":"J. Dermatol."},{"key":"B163","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0031000","article-title":"Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis.","volume":"7","author":"Zhang","year":"2012","journal-title":"PLoS One"},{"key":"B164","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/j.clindermatol.2013.11.005","article-title":"Acne as a chronic systemic disease.","volume":"32","author":"Zouboulis","year":"2014","journal-title":"Clin. Dermatol."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2018.01459\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T00:20:02Z","timestamp":1531182002000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2018.01459\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,10]]},"references-count":165,"alternative-id":["10.3389\/fmicb.2018.01459"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2018.01459","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,10]]},"article-number":"1459"}}