{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:17:39Z","timestamp":1787026659330,"version":"build-2736575974"},"reference-count":42,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:00:00Z","timestamp":1536105600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2018.01918","type":"journal-article","created":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:45:55Z","timestamp":1536108355000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":20,"title":["Production and Antimicrobial Activity of Nisin Under Enological Conditions"],"prefix":"10.3389","volume":"9","author":[{"given":"Roc\u00edo","family":"Fern\u00e1ndez-P\u00e9rez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolanda","family":"S\u00e1enz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Rojo-Bezares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Zarazaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan M.","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Tenorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Ruiz-Larrea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,9,5]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1007\/s12602-016-9227-9","article-title":"Effects of colistin and bacteriocins combinations on the in vitro growth of Escherichia coli strains from swine origin.","volume":"8","author":"Al Atya","year":"2016","journal-title":"Probiotics Antimicrob. Proteins"},{"key":"B2","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1111\/lam.12793","article-title":"Synergistic antibacterial and antibiofilm efficacy of nisin in combination with p-coumaric acid against food-borne bacteria Bacillus cereus and Salmonella typhimurium.","volume":"65","author":"Bag","year":"2017","journal-title":"Lett. Appl. Microbiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1111\/jam.13711","article-title":"Ethanol stress in Oenococcus oeni: transcriptional response and complex physiological mechanisms.","volume":"125","author":"Bonomo","year":"2018","journal-title":"J. Appl. Microbiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"2927","DOI":"10.1021\/ja3120955","article-title":"Synthesis and activity of biomimetic biofilm disruptors.","volume":"135","author":"B\u00f6ttcher","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/4034517","article-title":"Changes in the expression of biofilm-associated surface proteins in Staphylococcus aureus food-environmental isolates subjected to sublethal concentrations of disinfectants.","volume":"2016","author":"Cincarova","year":"2016","journal-title":"Biomed. Res. Int."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1111\/j.1365-2672.2011.05005","article-title":"The impact of nisin on sensitive and resistant mutants of Listeria monocytogenes in cottage cheese.","volume":"110","author":"Collins","year":"2011","journal-title":"J. Appl. Microbiol."},{"key":"B7","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1128\/AEM.57.2.601-603.1991","article-title":"Controlling wine malolactic fermentation with nisin and nisin-resistant strains of Leuconostoc oenos.","volume":"57","author":"Daeschel","year":"1991","journal-title":"Appl. Environ. Microbiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.ijfoodmicro.2017.05.017","article-title":"Transcriptome analysis shows activation of the arginine deiminase pathway in Lactococcus lactis as a response to ethanol stress.","volume":"257","author":"D\u00edez","year":"2017","journal-title":"Int. J. Food Microbiol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.peptides.2013.08.008","article-title":"In vitro pharmacokinetics of antimicrobial cationic peptides alone and in combination with antibiotics against methicillin resistant Staphylococcus aureus biofilms.","volume":"49","author":"Dosler","year":"2013","journal-title":"Peptides"},{"key":"B10","article-title":"Safety of nisin (E 234) as a food additive in the light of new toxicological data and the proposed extension of use.","volume":"15","year":"2017","journal-title":"EFSA J."},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00461","article-title":"Bacteriocins: novel solutions to age old spore-related problems?","volume":"7","author":"Egan","year":"2016","journal-title":"Front. Microbiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1007\/s00217-010-1331-6","article-title":"Rapid molecular methods for enumeration and taxonomical identification of acetic acid bacteria responsible for submerged vinegar production.","volume":"231","author":"Fern\u00e1ndez-P\u00e9rez","year":"2010","journal-title":"Eur. Food Res. Technol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1080\/21655979.2015.1049781","article-title":"Bioengineering of the model lantibiotic nisin.","volume":"6","author":"Field","year":"2015","journal-title":"Bioengineered"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00508","article-title":"In vitro activities of nisin and nisin derivatives alone and in combination with antibiotics against Staphylococcus biofilms.","volume":"7","author":"Field","year":"","journal-title":"Front. Microbiol."},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01713","article-title":"Synergistic nisin-polymyxin combinations for the control of Pseudomonas biofilm formation.","volume":"7","author":"Field","year":"","journal-title":"Front. Microbiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.ijfoodmicro.2007.06.001","article-title":"Bacteriocin-based strategies for food biopreservation.","volume":"120","author":"G\u00e1lvez","year":"2007","journal-title":"Int. J. Food Microbiol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"6149","DOI":"10.1021\/jf904529q","article-title":"Screening and selection of 2-branched (1,3)-\u03b2-d-glucan producing lactic acid bacteria and exopolysaccharide characterization.","volume":"58","author":"Garai-Ibabe","year":"2010","journal-title":"J. Agric. Food Chem."},{"key":"B18","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.foodchem.2015.02.101","article-title":"Selective methods for polyphenols and sulphur dioxide determination in wines.","volume":"182","author":"Garc\u00eda-Guzm\u00e1n","year":"2015","journal-title":"Food Chem."},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.02409","article-title":"Combination strategies to enhance the efficacy of antimicrobial peptides against bacterial biofilms.","volume":"8","author":"Grassi","year":"2017","journal-title":"Front. Microbiol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1111\/j.1365-2672.2006.03266.x","article-title":"Growth and exopolysaccharide (EPS) production by Oenococcus oeni I4 and structural characterization of their EPSs.","volume":"103","author":"Ibarburu","year":"2007","journal-title":"J. Appl. Microbiol."},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-8-143","article-title":"Staphylococcus epidermidis: a differential trait of the fecal microbiota of breast-fed infants.","volume":"8","author":"Jim\u00e9nez","year":"2008","journal-title":"BMC Microbiol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s00217-006-0529-0","article-title":"Evidence of mixed wild populations of Oenococcus oeni strains during wine spontaneous malolactic fermentations.","volume":"226","author":"L\u00f3pez","year":"2007","journal-title":"Eur. Food Res. Technol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"M196","DOI":"10.1111\/j.1750-3841.2008.00726.x","article-title":"Evaluation of exopolysaccharide production by Leuconostoc mesenteroides strains isolated from wine.","volume":"73","author":"Montersino","year":"2008","journal-title":"J. Food Sci."},{"key":"B24","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1002\/jib.233","article-title":"Nisin and its usage in breweries: a review and discussion.","volume":"121","author":"M\u00fcller-Auffermann","year":"2015","journal-title":"J. Inst. Brew."},{"key":"B25","doi-asserted-by":"crossref","first-page":"191","DOI":"10.5344\/ajev.2002.53.3.191","article-title":"Effect of bacteriocins pediocin PD-1, plantaricin 423, and nisin on biofilms of Oenococcus oeni on a stainless steel surface.","volume":"53","author":"Nel","year":"2002","journal-title":"Am. J. Enol. Vitic."},{"key":"B26","doi-asserted-by":"crossref","first-page":"176","DOI":"10.20873\/jbb.uft.cemaf.v4n3.neris","article-title":"Nisin in the biopreservation of Bord\u00f4 (Ives) and Ni\u00e1gara table wines from Santa Catarina.","volume":"4","author":"Neris","year":"2013","journal-title":"Br. J. Biotechnol. Biodivers."},{"key":"B27","year":"2014","journal-title":"Compendium of International Methods of Wine and Must Analysis. International Organisation of Vine and Wine"},{"key":"B28","doi-asserted-by":"publisher","first-page":"5572","DOI":"10.1128\/AAC.00888-13","article-title":"Effects of bacteriocins on methicillin-resistant Staphylococcus aureus biofilm.","volume":"57","author":"Okuda","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"key":"B29","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1046\/j.1365-2958.1998.00797","article-title":"Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, pathways convergent signalling: a genetic analysis.","volume":"28","author":"O\u2019Toole","year":"1998","journal-title":"Mol. Microbiol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"488","DOI":"10.17221\/545\/2015-CJFS","article-title":"Application of nisin \u2013 the well-known lactic acid bacteria bacteriocin \u2013 against spoilage bacteria in tangerine wine.","volume":"34","author":"Pei","year":"2016","journal-title":"Czech J. Food Sci."},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.00995","article-title":"Microbial resources and enological significance: opportunities and benefits.","volume":"8","author":"Petruzzi","year":"2017","journal-title":"Front. Microbiol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1016\/j.fm.2006.09.003","article-title":"Coculture-inducible bacteriocin activity of Lactobacillus plantarum strain J23 isolated from grape must.","volume":"24","author":"Rojo-Bezares","year":"","journal-title":"Food Microbiol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.ijfoodmicro.2006.12.020","article-title":"Antimicrobial activity of nisin against Oenococcus oeni and other wine bacteria.","volume":"116","author":"Rojo-Bezares","year":"","journal-title":"Int. J. Food Microbiol."},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00594","article-title":"Application of bacteriocins and protective cultures in dairy food preservation.","volume":"9","author":"Silva","year":"2018","journal-title":"Front. Microbiol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"53","DOI":"10.2174\/1874285801711010053","article-title":"Understanding the mechanism of bacterial biofilms resistance to antimicrobial agents.","volume":"11","author":"Singh","year":"2017","journal-title":"Open Microbiol. J."},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01643-17","article-title":"Formation of Staphylococcus aureus biofilm in the presence of sublethal concentrations of disinfectants studied via a transcriptomic analysis using transcriptome sequencing (RNA-seq).","volume":"83","author":"Slany","year":"2017","journal-title":"Appl. Environ. Microbiol."},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01939","article-title":"A bioengineered nisin derivative, M21A, in combination with food grade additives eradicates biofilms of Listeria monocytogenes.","volume":"7","author":"Smith","year":"2016","journal-title":"Front. Microbiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"190","DOI":"10.4103\/0975-962X.170372","article-title":"Antimicrobial effect of an oxazolidinone, lantibiotic and calcium hydroxide against Enterococcus faecalis biofilm: an in vitro study.","volume":"6","author":"Taneja","year":"2015","journal-title":"Indian J. Dent."},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0099513","article-title":"An in vitro study on the effect of free amino acids alone or in combination with nisin on biofilms as well as on planktonic bacteria of Streptococcus mutans.","volume":"9","author":"Tong","year":"2014","journal-title":"PLoS One"},{"key":"B40","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1038\/nrmicro2960","article-title":"Sticking together: building a biofilm the Bacillus subtilis way.","volume":"11","author":"Vlamakis","year":"2013","journal-title":"Nat. Rev. Microbiol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1007\/s00203-017-1446-2","article-title":"Mechanisms and improvement of acid resistance in lactic acid bacteria.","volume":"200","author":"Wang","year":"2018","journal-title":"Arch. Microbiol."},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00219-17","article-title":"PhoU2 but not PhoU1 as an important regulator of biofilm formation and tolerance to multiple stresses by participating in various fundamental metabolic processes in Staphylococcus epidermidis.","volume":"199","author":"Wang","year":"2017","journal-title":"J. Bacteriol."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2018.01918\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T17:38:49Z","timestamp":1693849129000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2018.01918\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,5]]},"references-count":42,"alternative-id":["10.3389\/fmicb.2018.01918"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2018.01918","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,5]]},"article-number":"1918"}}