{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:13:21Z","timestamp":1790738001212,"version":"4.1.0"},"reference-count":81,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T00:00:00Z","timestamp":1535673600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006492","name":"Division of Intramural Research, National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006492","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2018.02036","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T00:20:23Z","timestamp":1535674823000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":29,"title":["Global Profiling of Lysine Acetylation in Borrelia burgdorferi B31 Reveals Its Role in Central Metabolism"],"prefix":"10.3389","volume":"9","author":[{"given":"S\u00e9bastien","family":"Bontemps-Gallo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Gaviard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crystal L.","family":"Richards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takfarinas","family":"Kentache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra J.","family":"Raffel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin A.","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph C.","family":"Schindler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Lovelace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel P.","family":"Dulebohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert G.","family":"Cluss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Hardouin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank C.","family":"Gherardini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,8,31]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1093\/nar\/gkw1180","article-title":"In vivo expression technology and 5\u2032 end mapping of the Borrelia burgdorferi transcriptome identify novel RNAs expressed during mammalian infection.","volume":"45","author":"Adams","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2016.00038","article-title":"Post-translational serine\/threonine phosphorylation and lysine acetylation: a novel regulatory aspect of the global nitrogen response regulator glnR in S. coelicolor M145.","volume":"3","author":"Amin","year":"2016","journal-title":"Front. Mol. Biosci."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1109\/TCBB.2013.95","article-title":"Pareto optimality in organelle energy metabolism analysis.","volume":"10","author":"Angione","year":"2013","journal-title":"IEEE\/ACM Trans. Comput. Biol. Bioinform."},{"key":"B4","doi-asserted-by":"publisher","first-page":"4879","DOI":"10.1128\/JB.00659-13","article-title":"Measurements of mRNA degradation in Borrelia burgdorferi.","volume":"195","author":"Archambault","year":"","journal-title":"J. Bacteriol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.bbrc.2013.02.063","article-title":"Translational efficiency of rpoS mRNA from Borrelia burgdorferi: effects of the length and sequence of the mRNA leader region.","volume":"433","author":"Archambault","year":"","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B6","first-page":"521","article-title":"Isolation and cultivation of Lyme disease spirochetes.","volume":"57","author":"Barbour","year":"1984","journal-title":"Yale J. Biol. Med."},{"key":"B7","doi-asserted-by":"publisher","first-page":"2058","DOI":"10.1099\/ijsem.0.001815","article-title":"Division of the genus Borrelia into two genera (corresponding to Lyme disease and relapsing fever groups) reflects their genetic and phenotypic distinctiveness and will lead to a better understanding of these two groups of microbes (Margos et al. (2016) There is inadequate evidence to support the division of the genus Borrelia.","volume":"67","author":"Barbour","year":"2017","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"B8","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1128\/IAI.52.2.549-554.1986","article-title":"A Borrelia-specific monoclonal antibody binds to a flagellar epitope.","volume":"52","author":"Barbour","year":"1986","journal-title":"Infect. Immun."},{"key":"B9","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1016\/j.nbt.2014.03.002","article-title":"Regulation of bacterial physiology by lysine acetylation of proteins.","volume":"31","author":"Bernal","year":"2014","journal-title":"N. Biotechnol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1128\/JB.186.3.595-600.2004","article-title":"Lysogeny at mid-twentieth century: P1, P2, and other experimental systems.","volume":"186","author":"Bertani","year":"2004","journal-title":"J. Bacteriol."},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2016.00145","article-title":"Imaging the NADH:NAD+ homeostasis for understanding the metabolic response of mycobacterium to physiologically relevant stresses.","volume":"6","author":"Bhat","year":"2016","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"2902","DOI":"10.1128\/JB.01721-08","article-title":"Rrp2, a sigma54-dependent transcriptional activator of Borrelia burgdorferi, activates rpoS in an enhancer-independent manner.","volume":"191","author":"Blevins","year":"2009","journal-title":"J. Bacteriol."},{"key":"B13","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1126\/science.7043737","article-title":"Lyme disease-a tick-borne spirochetosis?","volume":"216","author":"Burgdorfer","year":"1982","journal-title":"Science"},{"key":"B14","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1111\/j.1365-2958.2007.05813.x","article-title":"Insights into the complex regulation of rpoS in Borrelia burgdorferi.","volume":"65","author":"Burtnick","year":"2007","journal-title":"Mol. Microbiol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"3846","DOI":"10.1111\/1462-2920.13897","article-title":"Sleeper cells: the stringent response and persistence in the Borreliella (Borrelia) burgdorferi enzootic cycle.","volume":"19","author":"Cabello","year":"2017","journal-title":"Environ. Microbiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1111\/cmi.12609","article-title":"Interaction of the Lyme disease spirochete with its tick vector.","volume":"18","author":"Caimano","year":"2016","journal-title":"Cell. Microbiol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"3043","DOI":"10.1128\/IAI.00315-15","article-title":"Cyclic di-GMP modulates gene expression in Lyme disease spirochetes at the tick-mammal interface to promote spirochete survival during the blood meal and tick-to-mammal transmission.","volume":"83","author":"Caimano","year":"2015","journal-title":"Infect. Immun."},{"key":"B18","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.jprot.2013.08.012","article-title":"Beyond gene expression: the impact of protein post-translational modifications in bacteria.","volume":"97","author":"Cain","year":"2014","journal-title":"J. Proteomics"},{"key":"B19","doi-asserted-by":"publisher","first-page":"e107","DOI":"10.1128\/JB.00107-17","article-title":"Regulation, function, and detection of protein acetylation in bacteria.","volume":"199","author":"Carabetta","year":"2017","journal-title":"J. Bacteriol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1046\/j.1365-2958.2000.01698.x","article-title":"A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi.","volume":"35","author":"Casjens","year":"2000","journal-title":"Mol. Microbiol."},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.15252\/msb.20145227","article-title":"Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli.","volume":"10","author":"Castano-Cerezo","year":"2014","journal-title":"Mol. Syst. Biol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"15590","DOI":"10.1074\/jbc.M112.352104","article-title":"System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases.","volume":"287","author":"Crosby","year":"2012","journal-title":"J. Biol. Chem."},{"key":"B23","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1128\/JB.181.8.2351-2357.1999","article-title":"The steady-state internal redox state (NADH\/NAD) reflects the external redox state and is correlated with catabolic adaptation in Escherichia coli.","volume":"181","author":"de Graef","year":"1999","journal-title":"J. Bacteriol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"2139","DOI":"10.1128\/IAI.70.4.2139-2150.2002","article-title":"Clonal polymorphism of Borrelia burgdorferi strain B31 MI: implications for mutagenesis in an infectious strain background.","volume":"70","author":"Elias","year":"2002","journal-title":"Infect. Immun."},{"key":"B25","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1038\/37551","article-title":"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.","volume":"390","author":"Fraser","year":"1997","journal-title":"Nature"},{"key":"B26","doi-asserted-by":"publisher","first-page":"5132","DOI":"10.1128\/JB.00340-08","article-title":"Biochemical and mutational analyses of AcuA, the acetyltransferase enzyme that controls the activity of the acetyl coenzyme a synthetase (AcsA) in Bacillus subtilis.","volume":"190","author":"Gardner","year":"2008","journal-title":"J. Bacteriol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"5460","DOI":"10.1128\/JB.00215-06","article-title":"Control of acetyl-coenzyme A synthetase (AcsA) activity by acetylation\/deacetylation without NAD+ involvement in Bacillus subtilis.","volume":"188","author":"Gardner","year":"2006","journal-title":"J. Bacteriol."},{"key":"B28","first-page":"103","article-title":"\u201cMetabolism and physiology of Borrelia,\u201d in","author":"Gherardini","year":"2010","journal-title":"Borrelia: Molecular Biology, Host Interaction and Pathogenesis"},{"key":"B29","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1111\/mmi.13339","article-title":"Lysine acetylation of the Mycobacterium tuberculosis HU protein modulates its DNA binding and genome organization.","volume":"100","author":"Ghosh","year":"2016","journal-title":"Mol. Microbiol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1111\/j.1365-2958.2007.05593.x","article-title":"Artificial regulation of ospC expression in Borrelia burgdorferi.","volume":"63","author":"Gilbert","year":"2007","journal-title":"Mol. Microbiol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"1986","DOI":"10.1099\/mic.0.068585-0","article-title":"Reversible acetylation regulates acetate and propionate metabolism in Mycobacterium smegmatis.","author":"Hayden","year":"2013","journal-title":"Microbiology"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1792","DOI":"10.1529\/biophysj.106.093138","article-title":"Thermodynamics-based metabolic flux analysis.","volume":"92","author":"Henry","year":"2007","journal-title":"Biophys. J."},{"key":"B33","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1128\/MMBR.00020-15","article-title":"Acylation of biomolecules in prokaryotes: a widespread strategy for the control of biological function and metabolic stress.","volume":"79","author":"Hentchel","year":"2015","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"B34","doi-asserted-by":"publisher","first-page":"4174","DOI":"10.1128\/JB.00383-13","article-title":"Acetylation of the response regulator RcsB controls transcription from a small RNA promoter.","volume":"195","author":"Hu","year":"2013","journal-title":"J. Bacteriol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/j.1365-2958.2010.07204.x","article-title":"Bacterial protein acetylation: the dawning of a new age.","volume":"77","author":"Hu","year":"2010","journal-title":"Mol. Microbiol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"D245","DOI":"10.1093\/nar\/gkm977","article-title":"The 20 years of PROSITE.","volume":"36","author":"Hulo","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"B37","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/0263-7855(96)00018-5","article-title":"VMD - visual molecular dynamics.","volume":"14","author":"Humphrey","year":"1996","journal-title":"J. Mol. Graph."},{"key":"B38","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.celrep.2015.12.015","article-title":"The cost of protein production.","volume":"14","author":"Kafri","year":"2016","journal-title":"Cell Rep."},{"key":"B39","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: kyoto encyclopedia of genes and genomes.","volume":"28","author":"Kanehisa","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"B40","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1111\/j.1365-2958.2011.07687.x","article-title":"The diguanylate cyclase, Rrp1, regulates critical steps in the enzootic cycle of the Lyme disease spirochetes.","volume":"81","author":"Kostick","year":"2011","journal-title":"Mol. Microbiol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"e38","DOI":"10.1016\/j.cell.2018.03.007","article-title":"Evolutionary convergence of pathway-specific enzyme expression stoichiometry.","volume":"173","author":"Lalanne","year":"2018","journal-title":"Cell"},{"key":"B42","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.jprot.2016.08.001","article-title":"Systematic analysis of the lysine acetylome of the pathogenic bacterium Spiroplasma eriocheiris reveals acetylated proteins related to metabolism and helical structure.","volume":"148","author":"Meng","year":"2016","journal-title":"J. Proteomics"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01894-17","article-title":"Ancient regulatory role of lysine acetylation in central metabolism.","volume":"8","author":"Nakayasu","year":"2017","journal-title":"mBio"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2014.00056","article-title":"The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi.","volume":"4","author":"Novak","year":"2014","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"B45","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1002\/pmic.201500258","article-title":"Protein lysine acetylation in bacteria: current state of the art.","volume":"16","author":"Ouidir","year":"2016","journal-title":"Proteomics"},{"key":"B46","doi-asserted-by":"publisher","first-page":"2641","DOI":"10.1099\/mic.0.2008\/019992-0","article-title":"Transcriptional interplay among the regulators Rrp2 RpoN and RpoS in Borrelia burgdorferi. Microbiology","author":"Ouyang","year":"2008"},{"key":"B47","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1093\/nar\/gkg148","article-title":"The ERGO genome analysis and discovery system.","volume":"31","author":"Overbeek","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"B48","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1016\/j.tim.2017.04.001","article-title":"Protein acetylation and its role in bacterial virulence.","volume":"25","author":"Ren","year":"2017","journal-title":"Trends Microbiol."},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0144472","article-title":"Acetyl-phosphate is not a global regulatory bridge between virulence and central metabolism in Borrelia burgdorferi.","volume":"10","author":"Richards","year":"2015","journal-title":"PLoS One"},{"key":"B50","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1111\/j.1365-2958.2009.06621.x","article-title":"Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions.","volume":"71","author":"Rogers","year":"2009","journal-title":"Mol. Microbiol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1385\/0-89603-310-4:253","article-title":"Electrotransformation of the spirochete Borrelia burgdorferi.","volume":"47","author":"Samuels","year":"1995","journal-title":"Methods Mol. Biol."},{"key":"B52","doi-asserted-by":"publisher","first-page":"1836","DOI":"10.1093\/infdis\/jiw028","article-title":"Protein Acetylation is involved in Salmonella enterica serovar Typhimurium virulence.","volume":"213","author":"Sang","year":"2016","journal-title":"J. Infect. Dis."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1126\/science.1217405","article-title":"Evolutionary trade-offs, Pareto optimality, and the geometry of phenotype space.","volume":"336","author":"Shoval","year":"2012","journal-title":"Science"},{"key":"B54","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1093\/bib\/3.3.265","article-title":"PROSITE: a documented database using patterns and profiles as motif descriptors.","volume":"3","author":"Sigrist","year":"2002","journal-title":"Brief. Bioinform."},{"key":"B55","doi-asserted-by":"publisher","first-page":"D344","DOI":"10.1093\/nar\/gks1067","article-title":"New and continuing developments at PROSITE.","volume":"41","author":"Sigrist","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"B56","doi-asserted-by":"publisher","first-page":"4060","DOI":"10.1093\/bioinformatics\/bti614","article-title":"ProRule: a new database containing functional and structural information on PROSITE profiles.","volume":"21","author":"Sigrist","year":"2005","journal-title":"Bioinformatics"},{"key":"B57","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1111\/j.1574-6968.1994.tb06713.x","article-title":"Effect of culture conditions on the NADH\/NAD ratio and total amounts of NAD(H) in chemostat cultures of Enterococcus faecalis NCTC 775.","volume":"116","author":"Snoep","year":"1994","journal-title":"FEMS Microbiol. Lett."},{"key":"B58","doi-asserted-by":"publisher","first-page":"3429","DOI":"10.1128\/JB.00085-08","article-title":"Reciprocal expression of ospA and ospC in single cells of Borrelia burgdorferi.","volume":"190","author":"Srivastava","year":"2008","journal-title":"J. Bacteriol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"26200","DOI":"10.1074\/jbc.M504863200","article-title":"Residue Leu-641 of Acetyl-CoA synthetase is critical for the acetylation of residue Lys-609 by the Protein acetyltransferase enzyme of Salmonella enterica.","volume":"280","author":"Starai","year":"2005","journal-title":"J. Biol. Chem."},{"key":"B60","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1056\/NEJM198303313081301","article-title":"The spirochetal etiology of Lyme disease.","volume":"308","author":"Steere","year":"1983","journal-title":"N. Engl. J. Med."},{"key":"B61","doi-asserted-by":"publisher","first-page":"2619","DOI":"10.1128\/JB.01885-07","article-title":"Flagellin and outer surface proteins from Borrelia burgdorferi are not glycosylated.","volume":"190","author":"Sterba","year":"2008","journal-title":"J. Bacteriol."},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1007\/82_2017_43","article-title":"Physiologic and genetic factors influencing the zoonotic cycle of Borrelia burgdorferi.","author":"Stewart","year":"2017","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034525","article-title":"Biochemical issues in estimation of cytosolic free NAD\/NADH ratio.","volume":"7","author":"Sun","year":"2012","journal-title":"PLoS One"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003163","article-title":"Evolutionary tradeoffs between economy and effectiveness in biological homeostasis systems.","volume":"9","author":"Szekely","year":"2013","journal-title":"PLoS Comput. Biol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"D447","DOI":"10.1093\/nar\/gku1003","article-title":"STRING v10: protein-protein interaction networks, integrated over the tree of life.","volume":"43","author":"Szklarczyk","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"B66","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/0471250953.bi0112s38","article-title":"Using the KEGG database resource.","volume":"1","author":"Tanabe","year":"2012","journal-title":"Curr. Protoc. Bioinformatics"},{"key":"B67","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.mib.2010.12.013","article-title":"Control of protein function by reversible Nvarepsilon-lysine acetylation in bacteria.","volume":"14","author":"Thao","year":"2011","journal-title":"Curr. Opin. Microbiol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"D158","DOI":"10.1093\/nar\/gkw1099","article-title":"UniProt: the universal protein knowledgebase.","volume":"45","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"B69","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1111\/mmi.13437","article-title":"Global Tn-seq analysis of carbohydrate utilization and vertebrate infectivity of Borrelia burgdorferi.","volume":"101","author":"Troy","year":"2016","journal-title":"Mol. Microbiol."},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.05322","article-title":"YcgC represents a new protein deacetylase family in prokaryotes.","volume":"4","author":"Tu","year":"2015","journal-title":"eLife"},{"key":"B71","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1111\/mmi.12088","article-title":"Acetoacetyl-CoA synthetase activity is controlled by a protein acetyltransferase with unique domain organization in Streptomyces lividans.","volume":"87","author":"Tucker","year":"2013","journal-title":"Mol. Microbiol."},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038171","article-title":"Effect of levels of acetate on the mevalonate pathway of Borrelia burgdorferi.","volume":"7","author":"Van Laar","year":"2012","journal-title":"PLoS One"},{"key":"B73","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.1016\/j.jmb.2017.03.027","article-title":"Studying the Lysine acetylation of malate dehydrogenase.","volume":"429","author":"Venkat","year":"2017","journal-title":"J. Mol. Biol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"22315","DOI":"10.1074\/jbc.M116.744532","article-title":"Post-translational acetylation of MbtA modulates mycobacterial siderophore biosynthesis.","volume":"291","author":"Vergnolle","year":"2016","journal-title":"J. Biol. Chem."},{"key":"B75","doi-asserted-by":"publisher","first-page":"D447","DOI":"10.1093\/nar\/gkv1145","article-title":"2016 update of the PRIDE database and its related tools.","volume":"44","author":"Vizcaino","year":"2016","journal-title":"Nucleic Acids Res."},{"key":"B76","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.femsle.2004.12.002","article-title":"Carbohydrate utilization by the Lyme borreliosis spirochete, Borrelia burgdorferi.","volume":"243","author":"von Lackum","year":"2005","journal-title":"FEMS Microbiol. Lett."},{"key":"B77","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.molcel.2014.03.027","article-title":"Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases.","volume":"54","author":"Wagner","year":"2014","journal-title":"Mol. Cell"},{"key":"B78","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1007\/s00294-015-0552-4","article-title":"Bacterial protein acetylation: new discoveries unanswered questions.","volume":"62","author":"Wolfe","year":"2016","journal-title":"Curr. Genet."},{"key":"B79","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1038\/nmeth.3213","article-title":"The I-TASSER suite: protein structure and function prediction.","volume":"12","author":"Yang","year":"2015","journal-title":"Nat. Methods"},{"key":"B80","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1007\/978-1-4939-7383-5_14","article-title":"Identification of Acetylated proteins in Borrelia burgdorferi.","volume":"1690","author":"Yang","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-9-40","article-title":"I-TASSER server for protein 3D structure prediction.","volume":"9","author":"Zhang","year":"2008","journal-title":"BMC Bioinformatics"}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2018.02036\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,8]],"date-time":"2020-11-08T10:24:02Z","timestamp":1604831042000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2018.02036\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,31]]},"references-count":81,"alternative-id":["10.3389\/fmicb.2018.02036"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2018.02036","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,31]]},"article-number":"2036"}}