{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T16:34:40Z","timestamp":1780936480425,"version":"3.54.1"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T00:00:00Z","timestamp":1542844800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP17fk0108121"],"award-info":[{"award-number":["JP17fk0108121"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP18fk0108048"],"award-info":[{"award-number":["JP18fk0108048"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP18fk0108019"],"award-info":[{"award-number":["JP18fk0108019"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2018.02853","type":"journal-article","created":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T05:13:18Z","timestamp":1542863598000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":20,"title":["Complete Genome Sequence of blaIMP\u20136-Positive Metakosakonia sp. MRY16-398 Isolate From the Ascites of a Diverticulitis Patient"],"prefix":"10.3389","volume":"9","author":[{"given":"Tsuyoshi","family":"Sekizuka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari","family":"Matsui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomiyo","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiko","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satowa","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Tokaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Kuroda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,11,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.meegid.2017.06.024","article-title":"Phylogenomics and comparative genomic studies delineate six main clades within the family Enterobacteriaceae and support the reclassification of several polyphyletic members of the family.","volume":"54","author":"Alnajar","year":"2017","journal-title":"Infect. Genet. Evol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1086\/421495","article-title":"Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 beta-lactamases in New York City.","volume":"39","author":"Bradford","year":"2004","journal-title":"Clin. Infect. Dis."},{"key":"B3","doi-asserted-by":"publisher","first-page":"3895","DOI":"10.1128\/AAC.02412-14","article-title":"In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing.","volume":"58","author":"Carattoli","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"B4","doi-asserted-by":"publisher","first-page":"D641","DOI":"10.1093\/nar\/gkr989","article-title":"VFDB 2012 update: toward the genetic diversity and molecular evolution of bacterial virulence factors.","volume":"40","author":"Chen","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"B5","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1038\/nmeth.2474","article-title":"Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data.","volume":"10","author":"Chin","year":"2013","journal-title":"Nat. Methods"},{"key":"B6","year":"2018","journal-title":"Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Eighth Informational Supplement M100\u2013S28"},{"key":"B7","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1093\/bioinformatics\/btu661","article-title":"A5-miseq: an updated pipeline to assemble microbial genomes from Illumina MiSeq data.","volume":"31","author":"Coil","year":"2015","journal-title":"Bioinformatics"},{"key":"B8","doi-asserted-by":"publisher","first-page":"2050","DOI":"10.1128\/jb.177.8.2050-2056.1995","article-title":"An Escherichia coli chromosomal ars operon homolog is functional in arsenic detoxification and is conserved in gram-negative bacteria.","volume":"177","author":"Diorio","year":"1995","journal-title":"J. Bacteriol."},{"key":"B9","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1128\/JCM.13.5.919-933.1981","article-title":"Kluyvera, a new (redefined) genus in the family Enterobacteriaceae: identification of Kluyvera ascorbata sp. nov. and Kluyvera cryocrescens sp. nov. in clinical specimens.","volume":"13","author":"Farmer","year":"1981","journal-title":"J. Clin. Microbiol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1086\/648451","article-title":"Risk factors and clinical impact of Klebsiella pneumoniae carbapenemase-producing K. pneumoniae.","volume":"30","author":"Gasink","year":"2009","journal-title":"Infect. Control Hosp. Epidemiol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1586\/14787210.2016.1106940","article-title":"Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE).","volume":"14","author":"Goodman","year":"2016","journal-title":"Expert Rev. Anti Infect. Ther."},{"key":"B12","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1017\/ice.2017.216","article-title":"Provider role in transmission of carbapenem-resistant Enterobacteriaceae.","volume":"38","author":"Grabowski","year":"2017","journal-title":"Infect. Control Hosp. Epidemiol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1111\/1469-0691.12678","article-title":"Detection of carbapenemases in Enterobacteriaceae: a challenge for diagnostic microbiological laboratories.","volume":"20","author":"Hrabak","year":"2014","journal-title":"Clin. Microbiol. Infect"},{"key":"B14","doi-asserted-by":"publisher","first-page":"3045","DOI":"10.1128\/AAC.46.9.3045-3049.2002","article-title":"Beta-lactamases of Kluyvera ascorbata, probable progenitors of some plasmid-encoded CTX-M types.","volume":"46","author":"Humeniuk","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"B15","doi-asserted-by":"publisher","first-page":"123","DOI":"10.5152\/tpa.2015.923","article-title":"Kluyvera ascorbata infections in children: a case series.","volume":"50","author":"Karadag Oncel","year":"2015","journal-title":"Turk. Pediatri. Ars."},{"key":"B16","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.ijantimicag.2017.03.012","article-title":"Carbapenem-resistant Enterobacteriaceae in the community: a scoping review.","volume":"50","author":"Kelly","year":"2017","journal-title":"Int. J. Antimicrob. Agents"},{"key":"B17","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1099\/jmm.0.050708-0","article-title":"Molecular characterization of carbapenemase-producing clinical isolates of Enterobacteriaceae in a teaching hospital.","author":"Koyano","year":"2013","journal-title":"Jpn. J. Med. Microbiol."},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.4210","article-title":"Translating genomics into practice for real-time surveillance and response to carbapenemase-producing Enterobacteriaceae: evidence from a complex multi-institutional KPC outbreak.","volume":"6","author":"Kwong","year":"2018","journal-title":"PeerJ"},{"key":"B19","doi-asserted-by":"publisher","first-page":"S28","DOI":"10.1093\/infdis\/jiw282","article-title":"The epidemiology of carbapenem-resistant Enterobacteriaceae: the impact and evolution of a global menace.","author":"Logan","year":"2017","journal-title":"J. Infect. Dis."},{"key":"B20","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1093\/bioinformatics\/btp105","article-title":"Integrall: a database and search engine for integrons, integrases and gene cassettes.","volume":"25","author":"Moura","year":"2009","journal-title":"Bioinformatics"},{"key":"B21","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.3201\/eid1809.120355","article-title":"Rapid detection of carbapenemase-producing Enterobacteriaceae.","volume":"18","author":"Nordmann","year":"2012","journal-title":"Emerg. Infect. Dis."},{"key":"B22","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1110\/ps.041093405","article-title":"Impact of remote mutations on metallo-beta-lactamase substrate specificity: implications for the evolution of antibiotic resistance.","volume":"14","author":"Oelschlaeger","year":"2005","journal-title":"Protein Sci."},{"key":"B23","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.jiac.2016.12.013","article-title":"Molecular epidemiology of carbapenemase-producing Enterobacteriaceae in a primary care hospital in Japan, 2010-2013.","volume":"23","author":"Ohno","year":"2017","journal-title":"J. Infect. Chemother."},{"key":"B24","doi-asserted-by":"publisher","first-page":"3125","DOI":"10.1093\/bioinformatics\/btq588","article-title":"Interactive microbial genome visualization with GView.","volume":"26","author":"Petkau","year":"2010","journal-title":"Bioinformatics"},{"key":"B25","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1128\/AAC.48.1.15-22.2004","article-title":"Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae.","volume":"48","author":"Poirel","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009490","article-title":"FastTree 2\u2013approximately maximum-likelihood trees for large alignments.","volume":"5","author":"Price","year":"2010","journal-title":"PLoS One"},{"key":"B27","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1128\/AAC.02271-13","article-title":"Detection of bla(GES-5) in carbapenem-resistant kluyvera intermedia isolates recovered from the hospital environment.","volume":"58","author":"Ribeiro","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1093\/jac\/dkx488","article-title":"Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae.","volume":"73","author":"Rozwandowicz","year":"2018","journal-title":"J. Antimicrob. Chemother."},{"key":"B29","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.mimet.2016.12.015","article-title":"Utilizing the Carba NP test as an indicator of expression level of carbapenemase genes in Enterobacteriaceae.","volume":"133","author":"Segawa","year":"2017","journal-title":"J. Microbiol. Methods"},{"key":"B30","doi-asserted-by":"publisher","first-page":"5407","DOI":"10.1128\/JCM.41.12.5407-5413.2003","article-title":"PCR typing of genetic determinants for metallo-beta-lactamases and integrases carried by gram-negative bacteria isolated in Japan, with focus on the class 3 integron.","volume":"41","author":"Shibata","year":"2003","journal-title":"J. Clin. Microbiol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1093\/bioinformatics\/btx713","article-title":"DFAST: a flexible prokaryotic genome annotation pipeline for faster genome publication.","volume":"34","author":"Tanizawa","year":"2018","journal-title":"Bioinformatics"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.01184-17","article-title":"Complete genome sequence of Kluyvera intestini sp. nov., isolated from the stomach of a patient with gastric cancer.","volume":"5","author":"Tetz","year":"2017","journal-title":"Genome Announc."},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0112963","article-title":"Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement.","volume":"9","author":"Walker","year":"2014","journal-title":"PLoS One"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5745708","article-title":"A case of biliary tract infection caused by KPC-2-producing Kluyvera ascorbata.","volume":"2018","author":"Wang","year":"2018","journal-title":"Case Rep. Infect. Dis."},{"key":"B35","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1128\/CMR.00023-13","article-title":"Trends in human fecal carriage of extended-spectrum beta-lactamases in the community: toward the globalization of CTX-M.","volume":"26","author":"Woerther","year":"2013","journal-title":"Clin. Microbiol. Rev."},{"key":"B36","year":"2017","journal-title":"Guidelines for the Prevention and Control of Carbapenem-Resistant Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosa in Health Care Facilities"},{"key":"B37","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.jhin.2017.07.015","article-title":"Prevalence of, and risk factors for, carriage of carbapenem-resistant Enterobacteriaceae among hospitalized patients in Japan.","volume":"97","author":"Yamamoto","year":"2017","journal-title":"J. Hosp. Infect."},{"key":"B38","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.idcr.2016.02.007","article-title":"Nosocomial bacteremia due to Kluyvera cryocrescens: case report and literature review.","volume":"4","author":"Yoshino","year":"2016","journal-title":"ID Cases"},{"key":"B39","doi-asserted-by":"publisher","first-page":"2640","DOI":"10.1093\/jac\/dks261","article-title":"Identification of acquired antimicrobial resistance genes.","volume":"67","author":"Zankari","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"B40","doi-asserted-by":"publisher","first-page":"7498","DOI":"10.1128\/AAC.01165-16","article-title":"Kluyvera ascorbata strain from hospital sewage carrying the mcr-1 colistin resistance gene.","volume":"60","author":"Zhao","year":"2016","journal-title":"Antimicrob. Agents Chemother."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2018.02853\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,15]],"date-time":"2020-11-15T18:54:50Z","timestamp":1605466490000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2018.02853\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,22]]},"references-count":40,"alternative-id":["10.3389\/fmicb.2018.02853"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2018.02853","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,22]]},"article-number":"2853"}}