{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:30:23Z","timestamp":1782887423333,"version":"3.54.5"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T00:00:00Z","timestamp":1548201600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2019.00007","type":"journal-article","created":{"date-parts":[[2019,1,23]],"date-time":"2019-01-23T06:10:13Z","timestamp":1548223813000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["An Inhibitory Effect of Dryocrassin ABBA on Staphylococcus aureus vWbp That Protects Mice From Pneumonia"],"prefix":"10.3389","volume":"10","author":[{"given":"Bangbang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingli","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panpan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianmei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjie","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiedong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dacheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,1,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.femsle.2004.03.040","article-title":"The von Willebrand factor-binding protein (vWbp) of Staphylococcus aureus is a coagulase.","volume":"234","author":"Bjerketorp","year":"2004","journal-title":"FEMS Microbiol. Lett."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001036","article-title":"Contribution of coagulases towards Staphylococcus aureus disease and protective immunity.","volume":"6","author":"Cheng","year":"2010","journal-title":"PLoS Pathog."},{"key":"B3","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.idc.2015.05.007","article-title":"Prevention of recurrent Staphylococcal skin infections.","volume":"29","author":"Creech","year":"2015","journal-title":"Infect. Dis. Clin. North Am."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1970","DOI":"10.1001\/jamainternmed.2013.10423","article-title":"National burden of invasive methicillin-resistant Staphylococcus aureus infections. United States, 2011.","volume":"173","author":"Dantes","year":"2013","journal-title":"JAMA Intern. Med."},{"key":"B5","doi-asserted-by":"publisher","first-page":"10089","DOI":"10.1063\/1.464397","article-title":"Particle mesh Ewald?: an Nlog (N) method for Ewald sums in large systems particle mesh Ewald?: an N -log (N) method for Ewald sums in large systems.","volume":"10089","author":"Darden","year":"2001","journal-title":"J. Chem. Phys."},{"key":"B6","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1128\/CMR.00081-09","article-title":"Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic.","volume":"23","author":"David","year":"2010","journal-title":"Clin. Microbiol. Rev."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1086\/503777","article-title":"Roles of 34 virulence genes in the evolution of hospital- and community-associated strains of methicillin-resistant Staphylococcus aureus.","volume":"193","author":"Diep","year":"2006","journal-title":"J. Infect. Dis."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1961","DOI":"10.1093\/jac\/dks142","article-title":"Efficacy of linezolid versus a pharmacodynamically optimized vancomycin therapy in an experimental pneumonia model caused by methicillin-resistant Staphylococcus aureus.","volume":"67","author":"Docobo-Perez","year":"2012","journal-title":"J. Antimicrob. Chemother."},{"key":"B9","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1111\/1574-6968.12040","article-title":"Apigenin alleviates the symptoms of Staphylococcus aureus pneumonia by inhibiting the production of alpha-hemolysin.","volume":"338","author":"Dong","year":"2013","journal-title":"FEMS Microbiol. Lett."},{"key":"B10","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.mimet.2017.05.008","article-title":"CRISPR\/dCas9-mediated inhibition of gene expression in Staphylococcus aureus.","volume":"139","author":"Dong","year":"2017","journal-title":"J. Microbiol. Methods"},{"key":"B11","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1016\/S0140-6736(07)61445-7","article-title":"Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial.","volume":"370","author":"Eriksson","year":"2007","journal-title":"Lancet"},{"key":"B12","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1038\/nature01962","article-title":"Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation.","volume":"425","author":"Friedrich","year":"2003","journal-title":"Nature"},{"key":"B13","doi-asserted-by":"publisher","first-page":"641","DOI":"10.3727\/096368914X678373","article-title":"Dryocrassin suppresses immunostimulatory function of dendritic cells and prolongs skin allograft survival.","volume":"23","author":"Fu","year":"2014","journal-title":"Cell Transplant."},{"key":"B14","doi-asserted-by":"publisher","first-page":"2060","DOI":"10.1046\/j.1538-7836.2003.00346.x","article-title":"Argatroban inhibits staphylothrombin.","volume":"1","author":"Hijikata-Okunomiya","year":"2003","journal-title":"J. Thromb. Haemost."},{"key":"B15","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1055\/s-2007-1002418","article-title":"A strategy for a rational approach to designing synthetic selective inhibitors.","volume":"18","author":"Hijikata-Okunomiya","year":"1992","journal-title":"Semin. Thromb. Hemost."},{"key":"B16","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1111\/j.1348-0421.1989.tb01511.x","article-title":"Improved methods for detection and serotyping coagulase from Staphylococcus aureus of clin ical pathology, Jis6n Jmior College of abstract improved methods for detection and serotyping of staphylocoagulase were concomitantly devised. We devised an impro.","volume":"33","author":"Hwang","year":"1989","journal-title":"Microbiol. Immunol."},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1063\/1.445869","article-title":"Comparison of simple potential functions for simulating liquid water comparison of simple potential functions for simulating liquid water.","volume":"79","author":"Jorgensen","year":"2001","journal-title":"J. Chem. Phys."},{"key":"B18","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/0304-3835(96)04275-9","article-title":"Anti-tumor promoting activity of Dryopteris phlorophenone derivatives.","volume":"105","author":"Kapadia","year":"1996","journal-title":"Cancer Lett."},{"key":"B19","doi-asserted-by":"publisher","first-page":"5060","DOI":"10.1128\/AAC.00985-09","article-title":"Pharmacodynamic profile of tigecycline against methicillin-resistant Staphylococcus aureus in an experimental pneumonia model.","volume":"53","author":"Koomanachai","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"B20","first-page":"1145","article-title":"Protein structure and enzyme action.","volume":"17","author":"Koshland","year":"1958","journal-title":"Fed. Proc."},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0081504","article-title":"A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated protein kinase kinase 4.","volume":"8","author":"Krishna","year":"2013","journal-title":"PLoS One"},{"key":"B22","doi-asserted-by":"publisher","first-page":"21984","DOI":"10.1073\/pnas.0910040106","article-title":"Target identification using drug affinity responsive target stability (DARTS).","volume":"106","author":"Lomenick","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B23","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1111\/1469-0691.12651","article-title":"Antimicrobial susceptibility testing in biofilm-growing bacteria.","volume":"20","author":"Macia","year":"2014","journal-title":"Clin. Microbiol. Infect."},{"key":"B24","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1001\/archinternmed.2008.536","article-title":"Exclusive staphylococcus aureus throat carriage: At-risk populations.","volume":"169","author":"Mertz","year":"2009","journal-title":"Arch. Intern. Med."},{"key":"B25","doi-asserted-by":"publisher","first-page":"925","DOI":"10.2165\/00003088-200443130-00005","article-title":"Pharmacodynamics of vancomycin and other antimicrobials in patients with Staphylococcus aureus lower respiratory tract infections.","volume":"43","author":"Moise-Broder","year":"2004","journal-title":"Clin. Pharmacokinet."},{"key":"B26","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.mib.2013.11.004","article-title":"Staphylococcus aureus toxins.","volume":"17","author":"Otto","year":"2014","journal-title":"Curr. Opin. Microbiol."},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.00592","article-title":"Dryocrassin ABBA, a novel active substance for use against amantadine-resistant H5N1 avian influenza virus.","volume":"6","author":"Ou","year":"2015","journal-title":"Front. Microbiol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1055\/s-0035-1549849","article-title":"Coagulase activity by Staphylococcus aureus: a potential target for therapy?","volume":"41","author":"Peetermans","year":"2015","journal-title":"Semin. Thromb. Hemost."},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.7748\/nop.29.6.11.s13","article-title":"Dabigatran versus warfarin in patients with atrial fibrillation.","volume":"29","author":"Sander","year":"2017","journal-title":"Nurs. Older People"},{"key":"B30","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1128\/IAI.65.2.466-471.1997","article-title":"Role of coagulase in a murine model of hematogenous pulmonary infection induced by intravenous injection of Staphylococcus aureus enmeshed in agar beads.","volume":"65","author":"Sawai","year":"1997","journal-title":"Infect. Immun."},{"key":"B31","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1128\/CMR.00134-14","article-title":"Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management.","volume":"28","author":"Tong","year":"2015","journal-title":"Clin. Microbiol. Rev."},{"key":"B32","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1093\/infdis\/jit130","article-title":"The role of staphylothrombin-mediated fibrin deposition in catheter-related Staphylococcus aureus infections.","volume":"208","author":"Vanassche","year":"2013","journal-title":"J. Infect. Dis."},{"key":"B33","doi-asserted-by":"publisher","first-page":"4248","DOI":"10.1128\/JCM.00896-10","article-title":"Dabigatran inhibits Staphylococcus aureus coagulase activity.","volume":"48","author":"Vanassche","year":"2010","journal-title":"J. Clin. Microbiol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1378\/chest.10-1556","article-title":"Linezolid vs glycopeptide antibiotics for the treatment of suspected methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a meta-analysis of randomized controlled trials.","volume":"139","author":"Walkey","year":"2011","journal-title":"Chest"},{"key":"B35","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1093\/jac\/dki416","article-title":"Effects of short interfering RNA against methicillin-resistant Staphylococcus aureus coagulase in vitro and in vivo.","volume":"57","author":"Yanagihara","year":"2006","journal-title":"J. Antimicrob. Chemother."},{"key":"B36","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.1093\/jac\/dky129","article-title":"Increased activity of linezolid in combination with rifampicin in a murine pneumonia model due to MRSA.","volume":"73","author":"Zhou","year":"2018","journal-title":"J. Antimicrob. Chemother."},{"key":"B37","doi-asserted-by":"publisher","first-page":"1645","DOI":"10.1056\/NEJMra040181","article-title":"Prosthetic-joint infections.","volume":"351","author":"Zimmerli","year":"2004","journal-title":"N. Engl. J. Med."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2019.00007\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T04:00:11Z","timestamp":1606104011000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2019.00007\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,23]]},"references-count":37,"alternative-id":["10.3389\/fmicb.2019.00007"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2019.00007","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,23]]},"article-number":"7"}}