{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T02:20:03Z","timestamp":1768270803263,"version":"3.49.0"},"reference-count":57,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T00:00:00Z","timestamp":1560124800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2019.01275","type":"journal-article","created":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T05:15:13Z","timestamp":1560230113000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Building of Pressure-Assisted Ultra-High Temperature System and Its Inactivation of Bacterial Spores"],"prefix":"10.3389","volume":"10","author":[{"given":"Dong","family":"Liang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojun","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaomeng","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaosong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,6,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1016\/j.ijfoodmicro.2006.08.012","article-title":"Inactivation kinetics of selected aerobic and anaerobic bacterial spores by pressure-assisted thermal processing.","volume":"113","author":"Ahn","year":"2007","journal-title":"Int. J. Food Microbiol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1205\/096030804322985362","article-title":"Adiabatic heat modelling for pressure build-up during high-pressure treatment in liquid-food processing.","volume":"82","author":"Ardia","year":"2004","journal-title":"Food Bioprod. Process."},{"key":"B3","doi-asserted-by":"publisher","first-page":"5879","DOI":"10.1128\/AEM.71.10.5879-5887.2005","article-title":"Factors influencing germination of Bacillus subtilis spores via activation of nutrient receptors by high pressure.","volume":"71","author":"Black","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1007\/s12393-016-9155-1","article-title":"A quasi-chemical model for bacterial spore germination kinetics by high pressure.","volume":"9","author":"Doona","year":"2017","journal-title":"Food Eng. Rev."},{"key":"B5","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1007\/s12393-015-9138-7","article-title":"Chemical kinetics for the microbial safety of foods treated with high pressure processing or hurdles.","volume":"8","author":"Doona","year":"","journal-title":"Food Eng. Rev."},{"key":"B6","doi-asserted-by":"publisher","first-page":"5287","DOI":"10.1128\/AEM.01363-16","article-title":"Effects of high-pressure treatment on spores of Clostridium species.","volume":"82","author":"Doona","year":"","journal-title":"Appl. Environ. Microbiol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1111\/jam.12557","article-title":"High pressure germination of Bacillus subtilis spores with alterations in levels and types of germination proteins.","volume":"117","author":"Doona","year":"2014","journal-title":"J. Appl. Microbiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/S0168-1605(00)00478-5","article-title":"A study on the effects of high pressure and heat on Bacillus subtilis spores at low pH.","volume":"64","author":"Elke","year":"2001","journal-title":"Int. J. Food Microbiol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1080\/08957950410001721173","article-title":"Warming of olive oil processed by high hydrostatic pressure.","volume":"24","author":"Hou\u0161ka","year":"2004","journal-title":"High Pressure Res."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1128\/AEM.03293-13","article-title":"High salinity alters the germination behavior of Bacillus subtilis spores with nutrient and nonnutrient germinants.","volume":"80","author":"Katja","year":"2013","journal-title":"Appl. Environ. Microbiol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1128\/AEM.03043-13","article-title":"Monitoring rates and heterogeneity of high-pressure germination of Bacillus spores by phase-contrast microscopy of individual spores.","volume":"80","author":"Kong","year":"2014","journal-title":"Appl. Environ. Microbiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"8717","DOI":"10.1021\/ac1022327","article-title":"Monitoring the kinetics of uptake of a nucleic acid dye during the germination of single spores of Bacillus species.","volume":"82","author":"Kong","year":"2010","journal-title":"Anal. Chem."},{"key":"B13","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1002\/9780470376409.ch9","article-title":"Determination of quality differences in low-acid foods sterilized by high pressure versus retorting","volume":"9","author":"Lau","year":"2007","journal-title":"High Pressure Processing of Food"},{"key":"B14","doi-asserted-by":"publisher","first-page":"2530","DOI":"10.1128\/JB.00259-13","article-title":"Activity and regulation of various forms of CwlJ, SleB, and YpeB proteins in degrading cortex peptidoglycan of spores of Bacillus species in vitro and during spore germination.","volume":"195","author":"Li","year":"2013","journal-title":"J. Bacteriol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1111\/1541-4337.12311","article-title":"Application of high pressure with homogenization, temperature, carbon dioxide, and cold plasma for the inactivation of Bacterial spores: a review.","volume":"17","author":"Lopes","year":"2018","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"B16","doi-asserted-by":"publisher","first-page":"2927","DOI":"10.1128\/AEM.00193-15","article-title":"The effects of heat activation on Bacillus spore germination, with nutrients or under high pressure, with or without various germination proteins.","volume":"81","author":"Luu","year":"2015","journal-title":"Appl. Environ. Microbiol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.ijfoodmicro.2014.12.016","article-title":"Carvacrol suppresses high pressure high temperature inactivation of Bacillus cereus spores.","volume":"197","author":"Luu-Thi","year":"2015","journal-title":"Int. J. Food Microbiol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"3476","DOI":"10.1128\/AEM.72.5.3476-3481.2006","article-title":"High-pressure-mediated survival of Clostridium botulinum and Bacillus amyloliquefaciens endospores at high temperature.","volume":"72","author":"Margosch","year":"2006","journal-title":"Appl. Environ. Microbiol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"2530","DOI":"10.4315\/0362-028X-67.11.2530","article-title":"Comparison of pressure and heat resistance of Clostridium botulinum and other endospores in mashed carrots.","volume":"67","author":"Margosch","year":"","journal-title":"J. Food Prot."},{"key":"B20","doi-asserted-by":"publisher","first-page":"7321","DOI":"10.1128\/AEM.70.12.7321-7328.2004","article-title":"Pressure inactivation of Bacillus endospores.","volume":"70","author":"Margosch","year":"","journal-title":"Appl. Environ. Microbiol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1016\/j.ifset.2007.06.010","article-title":"Flow cytometric assessment of Bacillus spore response to high pressure and heat.","volume":"8","author":"Mathys","year":"2007","journal-title":"Innov. Food Sci. Emerg. Technol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1080\/08957950802526469","article-title":"High pressure thermal sterilization \u2013 development and application of temperature controlled spore inactivation studies.","volume":"29","author":"Mathys","year":"2009","journal-title":"High Pressure Res."},{"key":"B23","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1016\/j.jfoodeng.2009.09.003","article-title":"Compressibility and density of select liquid and solid foods under pressures up to 700MPa.","volume":"96","author":"Min","year":"2010","journal-title":"J. Food Eng."},{"key":"B24","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.lwt.2009.09.022","article-title":"Evaluating the impact of thermal and pressure treatment in preserving textural quality of selected foods.","volume":"43","author":"Nguyen","year":"2010","journal-title":"LWT-Food Sci. Technol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.1128\/AEM.01957-10","article-title":"Strong and consistently synergistic inactivation of spores of spoilage-associated Bacillus and Geobacillus spp. by high pressure and heat compared with inactivation by heat alone.","volume":"77","author":"Olivier","year":"2011","journal-title":"Appl. Environ. Microbiol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"3172","DOI":"10.1128\/aem.68.6.3172-3175.2002","article-title":"Mechanisms of induction of germination of Bacillus subtilis spores by high pressure.","volume":"68","author":"Paidhungat","year":"2002","journal-title":"Appl. Environ. Microbiol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"2513","DOI":"10.1128\/JB.182.9.2513-2519.2000","article-title":"Role of Ger proteins in nutrient and nonnutrient triggering of spore germination in Bacillus subtilis.","volume":"182","author":"Paidhungat","year":"2000","journal-title":"J. Bacteriol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"2711","DOI":"10.1128\/JB.01832-08","article-title":"SleC is essential for cortex peptidoglycan hydrolysis during germination of spores of the pathogenic bacterium Clostridium perfringens.","volume":"191","author":"Paredes-Sabja","year":"2009","journal-title":"J. Bacteriol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.tim.2010.10.004","article-title":"Germination of spores of Bacillales and Clostridiales species: mechanisms and proteins involved.","volume":"19","author":"Paredes-Sabja","year":"2011","journal-title":"Trends Microbiol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.jfoodeng.2006.05.014","article-title":"Quasi-adiabatic temperature increase during high pressure processing of selected foods.","volume":"80","author":"Patazca","year":"2007","journal-title":"J. Food Eng."},{"key":"B31","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1080\/10408390701724371","article-title":"Estimating the heat resistance parameters of bacterial spores from their survival ratios at the end of UHT and other heat treatments.","volume":"48","author":"Peleg","year":"2008","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"B32","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1016\/j.fbp.2013.02.009","article-title":"Screening of twelve Clostridium botulinum (group I) spores for high-pressure resistance at elevated-temperatures.","volume":"91","author":"Ramaswamy","year":"2013","journal-title":"Food Bioprod. Process."},{"key":"B33","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1080\/08957950701385926","article-title":"Effect of polarity and molecular structure of selected liquids on their heat of compression during high pressure processing.","volume":"27","author":"Ramaswamy","year":"2007","journal-title":"High Pressure Res."},{"key":"B34","doi-asserted-by":"publisher","first-page":"253","DOI":"10.4315\/0362-028X.JFP-15-310","article-title":"Thermal and pressure-assisted thermal destruction kinetics for spores of type A Clostridium botulinum and Clostridium sporogenes PA3679.","volume":"79","author":"Reddy","year":"2016","journal-title":"J. Food Prot."},{"key":"B35","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.ifset.2012.10.009","article-title":"Structural analysis of high pressure treated Bacillus subtilis spores.","volume":"17","author":"Reineke","year":"","journal-title":"Innov. Food Sci. Emerg. Technol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.tim.2013.03.001","article-title":"Mechanisms of endospore inactivation under high pressure.","volume":"21","author":"Reineke","year":"","journal-title":"Trends Microbiol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.ijfoodmicro.2012.12.010","article-title":"The release of dipicolinic acid-the rate-limiting step of Bacillus endospore inactivation during the high pressure thermal sterilization process.","volume":"162","author":"Reineke","year":"","journal-title":"Int. J. Food Microbiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"M189","DOI":"10.1111\/j.1750-3841.2011.02066.x","article-title":"The impact of high pressure and temperature on bacterial spores: inactivation mechanisms of Bacillus subtilis above 500 MPa.","volume":"76","author":"Reineke","year":"2011","journal-title":"J. Food Sci."},{"key":"B39","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1111\/j.1365-2621.1992.tb11310.x","article-title":"Predicting thermophilic spore population dynamics for UHT sterilization processes.","volume":"57","author":"Sapru","year":"1992","journal-title":"J. Food Sci."},{"key":"B40","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3109\/1040841X.2013.788475","article-title":"High hydrostatic pressure-induced inactivation of bacterial spores.","volume":"41","author":"Sarker","year":"2015","journal-title":"Crit. Rev. Microbiol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1111\/j.1365-2672.2009.04210.x","article-title":"Characterization of the germination of Bacillus megaterium spores lacking enzymes that degrade the spore cortex.","volume":"107","author":"Setlow","year":"2009","journal-title":"J. Appl. Microbiol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"4759","DOI":"10.1128\/JB.00399-08","article-title":"Release of small molecules during germination of spores of Bacillus Species.","volume":"190","author":"Setlow","year":"2008","journal-title":"J. Bacteriol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1016\/j.mib.2003.10.001","article-title":"Spore germination.","volume":"6","author":"Setlow","year":"2003","journal-title":"Curr. Opin. Microbiol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1111\/j.1365-2672.2005.02736.x","article-title":"Spores of Bacillus subtilis: their resistance to and killing by radiation, heat and chemicals.","volume":"101","author":"Setlow","year":"2006","journal-title":"J. Appl. Microbiol."},{"key":"B45","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1111\/jam.14067","article-title":"Observations on research with spores of Bacillales and Clostridiales species.","volume":"126","author":"Setlow","year":"2018","journal-title":"J. Appl. Microbiol."},{"key":"B46","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1146\/annurev-micro-090816-093558","article-title":"Germination of spores of the orders Bacillales and Clostridiales.","volume":"71","author":"Setlow","year":"2017","journal-title":"Annu. Rev. Microbiol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.ifset.2013.07.006","article-title":"Effect of high pressure thermal sterilization on the formation of food processing contaminants.","volume":"20","author":"Sevenich","year":"2013","journal-title":"Innov. Food Sci. Emerg. Technol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1007\/s11947-008-0165-8","article-title":"Clostridium sporogenes-ATCC 7955 spore destruction kinetics in milk under high pressure and elevated temperature treatment conditions.","volume":"4","author":"Shao","year":"2008","journal-title":"Food Bioprocess Technol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/s11947-008-0057-y","article-title":"Compression heating and temperature control for high-pressure destruction of bacterial spores: an experimental method for kinetics evaluation.","volume":"3","author":"Shao","year":"2010","journal-title":"Food Bioprocess Technol."},{"key":"B50","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1128\/AEM.34.1.23-29.1977","article-title":"Thermal destruction of Clostridium botulinum spores suspended in tomato juice in aluminum thermal death time tubes.","volume":"34","author":"Theron","year":"1977","journal-title":"Appl. Environ. Microbiol."},{"key":"B51","first-page":"41","year":"2005","journal-title":"Principles of Thermal Processing."},{"key":"B52","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1128\/JB.01613-06","article-title":"Role of SpoVA proteins in release of dipicolinic acid during germination of Bacillus subtilis spores triggered by dodecylamine or lysozyme.","volume":"189","author":"Vepachedu","year":"2007","journal-title":"J. Bacteriol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.ijfoodmicro.2011.02.019","article-title":"Germination and inactivation of Bacillus coagulans and Alicyclobacillus acidoterrestris spores by high hydrostatic pressure treatment in buffer and tomato sauce.","volume":"152","author":"Vercammen","year":"2012","journal-title":"Int. J. Food Microbiol."},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.02047","article-title":"Analysis of the germination of individual Clostridium sporogenes spores with and without germinant receptors and cortex-lytic enzymes.","volume":"8","author":"Wang","year":"2017","journal-title":"Front. Microbiol."},{"key":"B55","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/j.tifs.2008.01.005","article-title":"High pressure in combination with elevated temperature as a method for the sterilisation of food.","volume":"19","author":"Wilson","year":"2008","journal-title":"Trends Food Sci. Technol."},{"key":"B56","doi-asserted-by":"publisher","first-page":"3424","DOI":"10.1128\/JB.00326-10","article-title":"Studies of the commitment step in the germination of spores of bacillus species.","volume":"192","author":"Yi","year":"2010","journal-title":"J. Bacteriol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.ijfoodmicro.2008.05.009","article-title":"High-pressure destruction kinetics of Clostridium sporogenes spores in ground beef at elevated temperatures.","volume":"126","author":"Zhu","year":"2008","journal-title":"Int. J. Food Microbiol."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2019.01275\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T04:55:47Z","timestamp":1608267347000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2019.01275\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,10]]},"references-count":57,"alternative-id":["10.3389\/fmicb.2019.01275"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2019.01275","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,10]]},"article-number":"1275"}}