{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:12:28Z","timestamp":1790172748538,"version":"4.1.0"},"reference-count":69,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,1,10]],"date-time":"2020-01-10T00:00:00Z","timestamp":1578614400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01 AI125421"],"award-info":[{"award-number":["R01 AI125421"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01 AI127793"],"award-info":[{"award-number":["R01 AI127793"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U19 AI144182"],"award-info":[{"award-number":["U19 AI144182"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2019.02981","type":"journal-article","created":{"date-parts":[[2020,1,10]],"date-time":"2020-01-10T04:46:24Z","timestamp":1578631584000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":26,"title":["Structural Basis for Evasion of Nutritional Immunity by the Pathogenic Neisseriae"],"prefix":"10.3389","volume":"10","author":[{"given":"Ravi","family":"Yadav","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Noinaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Ostan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor","family":"Moraes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Stoudenmire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stavros","family":"Maurakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia Nau","family":"Cornelissen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,1,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/mbo3.254","article-title":"Patterns of structural and sequence variation within isotype lineages of the Neisseria meningitidis transferrin receptor system.","volume":"4","author":"Adamiak","year":"2015","journal-title":"Microbiol. Open"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1046\/j.1365-2958.2003.03496.x","article-title":"Opposing selective forces for expression of the gonococcal lactoferrin receptor.","volume":"48","author":"Anderson","year":"2003","journal-title":"Mol. Microbiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1086\/324564","article-title":"Selection for expression of the gonococcal hemoglobin receptor during menses.","volume":"184","author":"Anderson","year":"2001","journal-title":"J. Inf. Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"3162","DOI":"10.1128\/jb.176.11.3162-3170.1994","article-title":"Gonococcal transferrin-binding protein 2 facilitates but is not essential for transferrin utilization.","volume":"176","author":"Anderson","year":"1994","journal-title":"J. Bacteriol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1002\/phar.1790","article-title":"History of meningococcal outbreaks in the United States: implications for vaccination and disease prevention.","volume":"36","author":"Atkinson","year":"2016","journal-title":"Pharmacotherapy"},{"key":"B6","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1039\/c2mt20037f","article-title":"Evidence of Fe3+ interaction with the plug domain of the outer membrane transferrin receptor protein of Neisseria gonorrhoeae: implications for Fe transport.","volume":"4","author":"Banerjee","year":"2012","journal-title":"Metallomics"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0133855","article-title":"Investigation into the antigenic properties and contributions to growth in blood of the meningococcal haemoglobin receptors, HpuAB and HmbR.","volume":"10","author":"Bidmos","year":"2015","journal-title":"PLoS One"},{"key":"B8","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/s10534-005-3251-7","article-title":"Neutrophil gelatinase-associated lipocalin, a siderophore-binding eukaryotic protein.","volume":"19","author":"Borregaard","year":"2006","journal-title":"Biometals"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1107\/S2053230X14019372","article-title":"The structure of lactoferrin-binding protein B from Neisseria meningitidis suggests roles in iron acquisition and neutralization of host defences.","volume":"70","author":"Brooks","year":"2014","journal-title":"Acta Crystallogr. F Struct. Biol. Commun."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8996","article-title":"The molecular mechanism of Zinc acquisition by the neisserial outer-membrane transporter ZnuD.","volume":"6","author":"Calmettes","year":"2015","journal-title":"Nat. Commun."},{"key":"B11","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1046\/j.1365-2958.2000.01873.x","article-title":"Phase variation of the gonococcal siderophore receptor FetA.","volume":"36","author":"Carson","year":"2000","journal-title":"Mol. Microbiol."},{"key":"B12","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1128\/JB.181.9.2895-2901.1999","article-title":"Ferric enterobactin binding and utilization by Neisseria gonorrhoeae.","volume":"181","author":"Carson","year":"1999","journal-title":"J. Bacteriol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"4438","DOI":"10.1128\/IAI.00762-15","article-title":"Beyond the crystal structure: insight into the function and vaccine potential of TbpA expressed by Neisseria gonorrhoeae.","volume":"83","author":"Cash","year":"2015","journal-title":"Infect. Immun."},{"key":"B14","year":"2015","journal-title":"Sexually Transmitted Diseases Treatment Guidelines."},{"key":"B15","year":"2017","journal-title":"Gonococcal Isolate Surveilance Project (GISP)."},{"key":"B16","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1128\/IAI.66.3.987-993.1998","article-title":"Phase variation of hemoglobin utilization in Neisseria gonorrhoeae.","volume":"66","author":"Chen","year":"1998","journal-title":"Infect. Immun."},{"key":"B17","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1128\/jb.184.2.420-426.2002","article-title":"Point mutations in HpuB enable gonococcal HpuA deletion mutants to grow on hemoglobin.","volume":"184","author":"Chen","year":"2002","journal-title":"J. Bacteriol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"4725","DOI":"10.1128\/iai.68.8.4725-4735.2000","article-title":"Antigenic and sequence diversity in gonococcal transferrin-binding protein A (TbpA).","volume":"68","author":"Cornelissen","year":"2000","journal-title":"Infect. Immun."},{"key":"B19","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1128\/IAI.65.2.822-828.1997","article-title":"Characterization of the diversity and the transferrin-binding domain of gonococcal transferrin-binding protein 2.","volume":"65","author":"Cornelissen","year":"1997","journal-title":"Infect. Immun."},{"key":"B20","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1046\/j.1365-2958.1998.00710.x","article-title":"The transferrin receptor expressed by gonococcal strain FA1090 is required for the experimental infection of human male volunteers.","volume":"27","author":"Cornelissen","year":"1998","journal-title":"Mol. Microbiol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1128\/jb.178.5.1437-1444.1996","article-title":"Binding and surface exposure characteristics of the gonococcal transferrin receptor are dependent on both transferrin-binding proteins.","volume":"178","author":"Cornelissen","year":"1996","journal-title":"J. Bacteriol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/0006-291x(62)90235-8","article-title":"The stability constants of the iron-transferrin complex.","volume":"8","author":"Davis","year":"1962","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B23","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1073\/pnas.1321556111","article-title":"Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum.","volume":"111","author":"Del Tordello","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B24","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1007\/s10534-008-9179-y","article-title":"Kinetic analysis of ligand interaction with the gonococcal transferrin-iron acquisition system.","volume":"22","author":"DeRocco","year":"2008","journal-title":"Biometals"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2018.23.27.1800323","article-title":"Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018.","volume":"23","author":"Eyre","year":"2018","journal-title":"Euro. Surveill."},{"key":"B26","doi-asserted-by":"publisher","first-page":"3183","DOI":"10.1128\/iai.00656-06","article-title":"The salmochelin siderophore receptor IroN contributes to invasion of urothelial cells by extraintestinal pathogenic Escherichia coli in vitro.","volume":"75","author":"Feldmann","year":"2007","journal-title":"Infect. Immun."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1920","DOI":"10.1099\/mic.0.068874-0","article-title":"Distribution and diversity of the haemoglobin-haptoglobin iron-acquisition systems in pathogenic and non-pathogenic Neisseria.","volume":"159","author":"Harrison","year":"2013","journal-title":"Microbiology"},{"key":"B28","doi-asserted-by":"crossref","first-page":"3937","DOI":"10.1128\/IAI.67.8.3937-3946.1999","article-title":"Limited local and systemic antibody responses to Neisseria gonorrheae during uncomplicated genital infections.","volume":"67","author":"Hedges","year":"1999","journal-title":"Infect. Immun."},{"key":"B29","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1086\/515372","article-title":"Cytokine and antibody responses in women infected with Neisseria gonorrhoeae: effects of concomitant infections.","volume":"178","author":"Hedges","year":"1998","journal-title":"J. Infect. Dis."},{"key":"B30","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1542\/pir.29-7-228","article-title":"Gonococcal infections.","volume":"29","author":"Holder","year":"2008","journal-title":"Ped. Rev."},{"key":"B31","doi-asserted-by":"publisher","first-page":"4764","DOI":"10.1128\/IAI.05806-11","article-title":"The iron-repressed, AraC-like regulator MpeR activates expression of fetA in Neisseria gonorrhoeae.","volume":"79","author":"Hollander","year":"2011","journal-title":"Infect. Immun."},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftx010","article-title":"Neisserial surface lipoproteins: structure, function and biogenesis.","volume":"75","author":"Hooda","year":"2017","journal-title":"Pathog. Dis."},{"key":"B33","first-page":"627","article-title":"Gonococcal infections in the adult","author":"Hook","year":"2008","journal-title":"Sexually Transmitted Diseases"},{"key":"B34","doi-asserted-by":"publisher","first-page":"2982","DOI":"10.1128\/IAI.00319-16","article-title":"Neisseria gonorrhoeae Evades calprotectin-mediated nutritional immunity and survives neutrophil extracellular traps by production of TdfH.","volume":"84","author":"Jean","year":"2016","journal-title":"Infect. Immun."},{"key":"B35","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1097\/00007435-199605000-00014","article-title":"Risk factors for pelvic inflammatory disease. A case control study.","volume":"23","author":"Jossens","year":"1996","journal-title":"Sex. Transm. Dis."},{"key":"B36","doi-asserted-by":"publisher","first-page":"6138","DOI":"10.1128\/jb.184.22.6138-6145.2002","article-title":"Demonstration and characterization of a specific interaction between gonococcal transferrin binding protein A and TonB.","volume":"184","author":"Kenney","year":"2002","journal-title":"J. Bacteriol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1099\/ijs.0.059774-0","article-title":"Towards a taxonomic coherence between average nucleotide identity and 16S rRNA gene sequence similarity for species demarcation of prokaryotes.","volume":"64","author":"Kim","year":"2014","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/978-3-642-65502-9_1","article-title":"The role of iron in bacterial infections, with special consideration of host-tubercle bacillus interaction.","volume":"60","author":"Kochan","year":"1973","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1016\/s0002-9378(98)70536-8","article-title":"Risk factors for plasma cell endometritis among women with cervical Neisseria gonorrhoeae, cervical Chlamydia trachomatis, or bacterial vaginosis.","volume":"178","author":"Korn","year":"1998","journal-title":"Am. J. Obstet. Gynecol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1128\/IAI.05208-11","article-title":"The Neisseria meningitidis ZnuD zinc receptor contributes to interactions with epithelial cells and supports heme utilization when expressed in Escherichia coli.","volume":"80","author":"Kumar","year":"2012","journal-title":"Infect. Immun."},{"key":"B41","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1046\/j.1365-2958.1999.01409.x","article-title":"Phase variation of HpuAB and HmbR, two distinct haemoglobin receptors of Neisseria meningitidis DNM2.","volume":"32","author":"Lewis","year":"1999","journal-title":"Mol. Microbiol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1046\/j.1365-2958.1997.2501619.x","article-title":"Molecular characterization of hpuAB, the haemoglobin-haptoglobin-utilization operon of Neisseria meningitidis.","volume":"23","author":"Lewis","year":"1997","journal-title":"Mol. Microbiol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"98","DOI":"10.4161\/viru.26515","article-title":"Meningococcal disease and the complement system.","volume":"5","author":"Lewis","year":"2014","journal-title":"Virulence"},{"key":"B44","doi-asserted-by":"publisher","first-page":"6843","DOI":"10.1073\/pnas.0502257102","article-title":"Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase response.","volume":"102","author":"Liuzzi","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007937","article-title":"The novel interaction between Neisseria gonorrhoeae TdfJ and human S100A7 allows gonococci to subvert host zinc restriction.","volume":"15","author":"Maurakis","year":"2019","journal-title":"PLoS Pathog."},{"key":"B46","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1146\/annurev.cellbio.16.1.423","article-title":"Interactions of pathogenic Neisseria with epithelial cell membranes.","volume":"16","author":"Merz","year":"2000","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1128\/AAC.01158-09","article-title":"Neutrophil gelatinase-associated lipocalin expresses antimicrobial activity by interfering with L-norepinephrine-mediated bacterial iron acquisition.","volume":"54","author":"Miethke","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"B48","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1016\/j.molcel.2009.06.029","article-title":"Insights into the bacterial transferrin receptor: the structure of transferrin-binding protein B from Actinobacillus pleuropneumoniae.","volume":"35","author":"Moraes","year":"2009","journal-title":"Mol. Cell"},{"key":"B49","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1007\/s10534-009-9217-4","article-title":"Salmochelin, the long-overlooked catecholate siderophore of Salmonella.","volume":"22","author":"Muller","year":"2009","journal-title":"Biometals"},{"key":"B50","doi-asserted-by":"publisher","first-page":"S21","DOI":"10.1016\/j.jadohealth.2016.04.013","article-title":"Treatment of meningococcal disease.","volume":"59","author":"Nadel","year":"2016","journal-title":"J. Adolesc. Health"},{"key":"B51","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1146\/annurev.bi.50.070181.003435","article-title":"Microbial iron compounds.","volume":"50","author":"Neilands","year":"1981","journal-title":"Annu. Rev. Biochem."},{"key":"B52","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1111\/mmi.12002","article-title":"The transferrin-iron import system from pathogenic Neisseria species.","volume":"86","author":"Noinaj","year":"2012","journal-title":"Mol. Microbiol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.jsb.2013.02.009","article-title":"Structural insight into the lactoferrin receptors from pathogenic Neisseria.","volume":"184","author":"Noinaj","year":"2013","journal-title":"J. Struct. Biol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"1960","DOI":"10.1128\/IAI.00020-08","article-title":"Identification of TbpA residues required for transferrin-iron utilization by Neisseria gonorrhoeae.","volume":"76","author":"Noto","year":"2008","journal-title":"Infect. Immun."},{"key":"B55","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1128\/iai.72.1.277-283.2004","article-title":"Immunogenicity of gonococcal transferrin binding proteins during natural infections.","volume":"72","author":"Price","year":"2004","journal-title":"Infect. Immun."},{"key":"B56","doi-asserted-by":"publisher","first-page":"7247","DOI":"10.1016\/j.vaccine.2007.07.038","article-title":"Gonococcal transferrin binding protein chimeras induce bactericidal and growth inhibitory antibodies in mice.","volume":"25","author":"Price","year":"2007","journal-title":"Vaccine"},{"key":"B57","doi-asserted-by":"publisher","first-page":"3945","DOI":"10.1128\/iai.73.7.3945-3953.2005","article-title":"Intranasal administration of recombinant Neisseria gonorrhoeae transferrin binding proteins A and B conjugated to the cholera toxin B subunit induces systemic and vaginal antibodies in mice.","volume":"73","author":"Price","year":"2005","journal-title":"Infect. Immun."},{"key":"B58","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1038\/nrmicro.2017.169","article-title":"Neisseria gonorrhoeae host adaptation and pathogenesis.","volume":"16","author":"Quillin","year":"2018","journal-title":"Nat. Rev."},{"key":"B59","doi-asserted-by":"publisher","first-page":"3083","DOI":"10.1128\/IAI.01193-09","article-title":"NalP-mediated proteolytic release of lactoferrin-binding protein B from the meningococcal cell surface.","volume":"78","author":"Roussel-Jazede","year":"2010","journal-title":"Infect. Immun."},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056746","article-title":"Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis.","volume":"8","author":"Saleem","year":"2013","journal-title":"PLoS One"},{"key":"B61","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1111\/j.1365-2958.1995.tb02266.x","article-title":"The Neisseria meningitidis haemoglobin receptor: its role in iron utilization and virulence.","volume":"15","author":"Stojiljkovic","year":"1995","journal-title":"Mol. Microbiol."},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000969","article-title":"An outer membrane receptor of Neisseria meningitidis involved in zinc acquisition with vaccine potential.","volume":"6","author":"Stork","year":"2010","journal-title":"PLoS Pathog."},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003733","article-title":"Zinc piracy as a mechanism of Neisseria meningitidis for evasion of nutritional immunity.","volume":"9","author":"Stork","year":"2013","journal-title":"PLoS Pathog."},{"key":"B64","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/s0140-6736(06)67932-4","article-title":"Clinical recognition of meningococcal disease in children and adolescents.","volume":"367","author":"Thompson","year":"2006","journal-title":"Lancet"},{"key":"B65","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1093\/ajcn\/30.9.1485","article-title":"Infection and iron metabolism.","volume":"30","author":"Weinberg","year":"1977","journal-title":"Am. J. Clin. Nutr."},{"key":"B66","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1128\/MR.42.1.45-66.1978","article-title":"Iron and infection.","volume":"42","author":"Weinberg","year":"1978","journal-title":"Microbiol. Rev."},{"key":"B67","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1211\/0022357011777792","article-title":"Human lactoferrin: a novel therapeutic with broad spectrum potential.","volume":"53","author":"Weinberg","year":"2001","journal-title":"J. Pharm. Pharmacol."},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10172","article-title":"Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family.","volume":"6","author":"Wong","year":"2015","journal-title":"Nat. Commun."},{"key":"B69","doi-asserted-by":"publisher","first-page":"18991","DOI":"10.1074\/jbc.R115.645085","article-title":"Nutritional Immunity: S100 proteins at the host-pathogen interface.","volume":"290","author":"Zackular","year":"2015","journal-title":"J. Biol. Chem."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2019.02981\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T17:00:04Z","timestamp":1613926804000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2019.02981\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,10]]},"references-count":69,"alternative-id":["10.3389\/fmicb.2019.02981"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2019.02981","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,10]]},"article-number":"2981"}}