{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:36:31Z","timestamp":1785890191884,"version":"3.56.0"},"reference-count":75,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T00:00:00Z","timestamp":1582848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2020.00307","type":"journal-article","created":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T12:23:10Z","timestamp":1582892590000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":76,"title":["The Role of Candida albicans Secreted Polysaccharides in Augmenting Streptococcus mutans Adherence and Mixed Biofilm Formation: In vitro and in vivo Studies"],"prefix":"10.3389","volume":"11","author":[{"given":"Zaid H.","family":"Khoury","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taissa","family":"Vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taanya R.","family":"Puthran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed S.","family":"Sultan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Montelongo-Jauregui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Anne S.","family":"Melo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Ann","family":"Jabra-Rizk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,2,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1099\/jmm.0.46569-0","article-title":"Biofilm matrix of Candida albicans and Candida tropicalis: chemical composition and role in drug resistance.","volume":"55","author":"Al-Fattani","year":"2006","journal-title":"J. Med. Microbiol."},{"key":"B2","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1590\/S1517-83822007000400009","article-title":"Analysis of the in vitro adherence of Streprococcus mutans and Candida albicans.","volume":"38","author":"Barbieri","year":"2007","journal-title":"Braz. J. Microbiol."},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007717","article-title":"Candida albicans induces mucosal bacterial dysbiosis that promotes invasive infection.","volume":"15","author":"Bertolini","year":"2019","journal-title":"PLoS Pathog."},{"key":"B4","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1159\/000324598","article-title":"Biology of Streptococcus mutans-derived glucosyltransferases: role in extracellular matrix formation of cariogenic biofilms.","volume":"45","author":"Bowen","year":"2011","journal-title":"Caries Res."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1016\/j.archoralbio.2006.06.001","article-title":"Presence of mutans streptococci and Candida spp. in dental plaque\/dentine of carious teeth and early childhood caries.","volume":"51","author":"de Carvalho","year":"2006","journal-title":"Arch. Oral. Biol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1128\/IAI.05896-11","article-title":"Synergistic interaction between Candida albicans and commensal oral streptococci in a novel in vitro mucosal model.","volume":"80","author":"Diaz","year":"2012","journal-title":"Infect. Immun."},{"key":"B7","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.micinf.2015.03.014","article-title":"Beyond microbial community composition: functional activities of the oral microbiome in health and disease.","volume":"17","author":"Duran-Pinedo","year":"2015","journal-title":"Microbes Infect."},{"key":"B8","author":"Calderone","year":"2012","journal-title":"Candida and Candidiasis."},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1590\/1678-7757-2018-0593","article-title":"Role of Candida albicans on enamel demineralization and on acidogenic potential of Streptococcus mutans in vitro biofilms.","volume":"9","author":"Eidt","year":"2019","journal-title":"J. Appl. Oral. Sci."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1177\/0022034517714414","article-title":"Bacterial GtfB augments Candida albicans accumulation in cross-kingdom biofilms.","volume":"96","author":"Ellepola","year":"2017","journal-title":"J. Dent. Res."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1968","DOI":"10.1128\/IAI.00087-14","article-title":"Symbiotic relationship between Streptococcus mutans and Candida albicans synergizes the virulence of plaque-biofilms in vivo.","volume":"82","author":"Falsetta","year":"2014","journal-title":"Infect. Immun."},{"key":"B12","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1177\/0022034511399284","article-title":"Candida-host interactions in HIV disease implications for oropharyngeal candidiasis.","volume":"23","author":"Fidel","year":"2011","journal-title":"Adv. Dent. Res."},{"key":"B13","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1007\/s40368-016-0239-7","article-title":"Streptococcus mutans, Streptococcus sobrinus and Candida albicans in oral samples from caries-free and caries-active children.","volume":"17","author":"Fragkou","year":"2016","journal-title":"Eur. Arch. Paediatr Dent."},{"key":"B14","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/bf00328721","article-title":"Isolation of the Candida albicans gene for orotidine\u20185\u2019-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations.","volume":"198","author":"Gillum","year":"1984","journal-title":"Molec. Gen. Genet."},{"key":"B15","doi-asserted-by":"publisher","first-page":"6357","DOI":"10.1128\/AEM.05203-11","article-title":"Role of glucosyltransferase B in interactions of Candida albicans with Streptococcus mutans and with an experimental pellicle on hydroxyapatite surfaces.","volume":"77","author":"Gregoire","year":"2011","journal-title":"Appl. Environ. Microbiol."},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftw039","article-title":"Candida albicans in oral biofilms could prevent caries.","volume":"74","author":"Hubertine","year":"2016","journal-title":"Pathog. Dis."},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006407","article-title":"Candida albicans mannans mediate Streptococcus mutans exoenzyme GtfB binding to modulate cross-kingdom biofilm development in vivo.","volume":"13","author":"Hwang","year":"2017","journal-title":"PLoS Pathog."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.1177\/0022034515592859","article-title":"Binding force dynamics of Streptococcus mutans\u2013glucosyltransferase B to Candida albicans.","volume":"94","author":"Hwang","year":"2015","journal-title":"J. Dent. Res."},{"key":"B19","first-page":"RA196","article-title":"Dental caries: from infection to prevention.","volume":"13","author":"Isalm","year":"2007","journal-title":"Med. Sci. Monit."},{"key":"B20","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1080\/08927014.2014.894028","article-title":"In vitro evaluation of adherence of Candida albicans, Candida glabrata, and Streptococcus mutans to an acrylic resin modified by experimental coatings.","volume":"30","author":"Izumida","year":"2014","journal-title":"Biofouling"},{"key":"B21","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3201\/eid1001.030119","article-title":"Fungal biofilms and drug resistance.","volume":"10","author":"Jabra-Rizk","year":"2004","journal-title":"Emerg. Infect. Dis."},{"key":"B22","doi-asserted-by":"publisher","first-page":"2724","DOI":"10.1128\/IAI.00469-16","article-title":"Candida albicans pathogenesis: fitting within the host-microbe damage response framework.","volume":"84","author":"Jabra-Rizk","year":"2016","journal-title":"Infect. Immun."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1658","DOI":"10.1128\/EC.00070-09","article-title":"Streptococcus mutans competence-stimulating peptide inhibits Candida albicans hypha formation.","volume":"8","author":"Jarosz","year":"2009","journal-title":"Eukaryot. Cell"},{"key":"B24","first-page":"1","article-title":"Candida albicans \u2013 bacteria interactions in biofilms and disease.","author":"Jenkinson","year":"2008","journal-title":"Univ. Bristol Dent. Sch."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1128\/iai.58.5.1429-1436.1990","article-title":"Coaggregation of Streptococcus sanguis and other streptococci with Candida albicans.","volume":"58","author":"Jenkinson","year":"1990","journal-title":"Infect. Immun."},{"key":"B26","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1016\/j.tim.2005.09.006","article-title":"Oral microbial communities in sickness and in health.","volume":"13","author":"Jenkinson","year":"2005","journal-title":"Trends Microbiol."},{"key":"B27","doi-asserted-by":"crossref","first-page":"C35","DOI":"10.1177\/154405910408301s07","article-title":"What constitutes dental caries? Histopathology of carious enamel and dentin related to the action of cariogenic biofilms.","volume":"83","author":"Kidd","year":"2004","journal-title":"J. Den. Res."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1038\/s41396-018-0113-1","article-title":"Bacterial-derived exopolysaccharides enhance antifungal drug tolerance in a cross-kingdom oral biofilm.","volume":"12","author":"Kim","year":"2018","journal-title":"ISME J."},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2015.00010","article-title":"Streptococcus mutans-derived extracellular matrix in cariogenic oral biofilms.","volume":"5","author":"Klein","year":"2015","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1159\/000324809","article-title":"Dental caries in rats associated with Candida albicans.","volume":"45","author":"Klinke","year":"2011","journal-title":"Caries Res."},{"key":"B31","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1128\/MMBR.66.3.486-505.2002","article-title":"Communication among oral bacteria.","volume":"66","author":"Kolenbrander","year":"2002","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"B32","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1128\/IAI.02843-14","article-title":"Clinical implications of oral candidiasis: host tissue damage and disseminated bacterial disease.","volume":"83","author":"Kong","year":"2015","journal-title":"Infect. Immun."},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01365-16","article-title":"Commensal protection of Staphylococcus aureus against antimicrobials by Candida albicans biofilm matrix.","volume":"7","author":"Kong","year":"2016","journal-title":"mBio"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007342","article-title":"Candida\u2013streptococcal interactions in biofilm-associated oral diseases.","volume":"14","author":"Koo","year":"2018","journal-title":"PLoS Pathog."},{"key":"B35","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.2217\/fmb.14.92","article-title":"Candida albicans and Streptococcus mutans: a potential synergistic alliance to cause virulent tooth decay in children.","volume":"9","author":"Koo","year":"2014","journal-title":"Future Microbiol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1177\/0022034513504218","article-title":"The exopolysaccharide matrix: a virulence determinant of cariogenic biofilm.","volume":"92","author":"Koo","year":"2013","journal-title":"J. Dent. Res."},{"key":"B37","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1177\/0022034514521814","article-title":"Candida and other fungal species: forgotten players of healthy oral microbiota.","volume":"93","author":"Krom","year":"2014","journal-title":"J. Dent. Res."},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1006452","article-title":"Functional genomic analysis of Candida albicans adherence reveals a key role for the Arp2\/3 complex in cell wall remodelling and biofilm formation.","volume":"12","author":"Lee","year":"2016","journal-title":"PLoS Genet."},{"key":"B39","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1099\/mic.0.066134-0","article-title":"Streptococcus mutans: a new gram-positive paradigm?","volume":"159","author":"Lemos","year":"2013","journal-title":"Microbiology"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1080\/20002297.2019.1581520","article-title":"Dual-species biofilms of Streptococcus mutans and Candida albicans exhibit more biomass and are mutually beneficial compared with single-species biofilms.","volume":"11","author":"Lobo","year":"2019","journal-title":"J. Oral. Microbiol."},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003616","article-title":"Streptococcus mutans, Candida albicans and the human mouth: a sticky situation.","volume":"9","author":"Metwalli","year":"2013","journal-title":"PLoS Pathog."},{"key":"B42","doi-asserted-by":"publisher","first-page":"4092","DOI":"10.1073\/pnas.1421437112","article-title":"Community participation in biofilm matrix assembly and function.","volume":"112","author":"Mitchell","year":"2015","journal-title":"Proc. Nat. Acad. Sci. U.S.A."},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.3390\/jof4040122","article-title":"Candida interactions with the oral bacterial microbiota.","volume":"4","author":"Montelongo-Jauregui","year":"2018","journal-title":"J. Fungi"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01179-01119","article-title":"Contributions of Candida albicans dimorphism, adhesive interactions, and extracellular matrix to the formation of dual-species biofilms with Streptococcus gordonii.","volume":"10","author":"Montelongo-Jauregui","year":"2019","journal-title":"mBio"},{"key":"B45","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1074\/jbc.m411413200","article-title":"Mnt1p and Mnt2p of Candida albicans are partially redundant \u03b1-1, 2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence.","volume":"280","author":"Munro","year":"2005","journal-title":"J. Biol. Chem."},{"key":"B46","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.mib.2006.06.007","article-title":"Candida albicans biofilm development, modeling a host-pathogen interaction.","volume":"9","author":"Nett","year":"2006","journal-title":"Curr. Opin. Microbiol."},{"key":"B47","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1128\/aac.01056-06","article-title":"Putative role of beta-1,3 glucans in Candida albicans biofilm resistance.","volume":"51","author":"Nett","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"key":"B48","doi-asserted-by":"publisher","first-page":"1660","DOI":"10.1128\/EC.05126-11","article-title":"Interface of Candida albicans biofilm matrix-associated drug resistance and cell wall integrity regulation.","volume":"10","author":"Nett","year":"2011","journal-title":"Eukaryot. Cell"},{"key":"B49","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1111\/odi.12691","article-title":"Is the oral fungal pathogen Candida albicans a cariogen?","volume":"24","author":"Pereira","year":"2018","journal-title":"Oral Dis."},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.3390\/jof3010014","article-title":"The Candida albicans biofilm matrix: Composition, structure and function.","volume":"3","author":"Pierce","year":"2017","journal-title":"J. Fungi (Basel)"},{"key":"B51","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1159\/000314675","article-title":"Association of oral candidal carriage with dental caries in children.","volume":"44","author":"Raja","year":"2010","journal-title":"Caries Res."},{"key":"B52","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1128\/EC.4.4.633-638.2005","article-title":"Candida biofilms: an update.","volume":"4","author":"Ramage","year":"2005","journal-title":"Eukaryot. Cell"},{"key":"B53","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/s0966-842x(02)00034-3","article-title":"Bacterial coaggregation: an integral process in the development of multi-species biofilms.","volume":"11","author":"Rickard","year":"2003","journal-title":"Trends Microbiol."},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.3402\/jom.v6.23419","article-title":"Streptococcus gordonii glucosyltransferase promotes biofilm interactions with Candida albicans.","volume":"6","author":"Ricker","year":"2014","journal-title":"J. Oral. Microbiol."},{"key":"B55","doi-asserted-by":"publisher","first-page":"27","DOI":"10.2174\/1874437001206010027","article-title":"Diseases anssociated with oral polymicrobial biofilms.","volume":"6","author":"Rouabhia","year":"2012","journal-title":"Open Mycol. J."},{"key":"B56","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1159\/000494033","article-title":"Candida albicans increases dentine demineralization provoked by Streptococcus mutans biofilm.","volume":"53","author":"Sampaio","year":"2019","journal-title":"Caries Res."},{"key":"B57","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1038\/nprot.2012.011","article-title":"Mouse model of oropharyngeal candidiasis.","volume":"7","author":"Solis","year":"2012","journal-title":"Nat. Prot."},{"key":"B58","doi-asserted-by":"publisher","first-page":"7439","DOI":"10.1128\/jb.181.24.7439-7448.1999","article-title":"Molecular analysis of the Candida albicans homolog of Saccharomyces cerevisiae MNN9, required for glycosylation of wall mannoproteins.","volume":"181","author":"Southard","year":"1999","journal-title":"J. Bacteriol."},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006719","article-title":"The oral microbiome: a lesson in co-existence.","volume":"14","author":"Sultan","year":"2018","journal-title":"PLoS Pathog."},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2014.73","article-title":"Cross-feeding and interkingdom communication in dual-species biofilms of Streptococcus mutans and Candida albicans.","volume":"8","author":"Sztajer","year":"2014","journal-title":"ISME J."},{"key":"B61","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1177\/0022034517736496","article-title":"The caries microbiome: implications for reversing dysbiosis.","volume":"29","author":"Tanner","year":"2018","journal-title":"Adv. Dent. Res."},{"key":"B62","doi-asserted-by":"publisher","first-page":"2956","DOI":"10.1016\/j.jmb.2019.05.016","article-title":"The structure of dental plaque microbial communities in the transition from health to dental caries and periodontal disease.","volume":"431","author":"Valm","year":"2019","journal-title":"J. Mol. Biol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"2535","DOI":"10.3390\/molecules14072535","article-title":"Bacterial extracellular polysaccharides involved in biofilm formation.","volume":"14","author":"Vu","year":"2009","journal-title":"Molecules"},{"key":"B64","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.phrs.2012.11.006","article-title":"The oral microbiome in health and disease.","volume":"69","author":"Wade","year":"2013","journal-title":"Pharmacol. Res."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.mib.2019.04.001","article-title":"Candida albicans biofilm growth and dispersal: contributions to pathogenesis.","volume":"11","author":"Wall","year":"2019","journal-title":"Curr. Opin. Microbiol."},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.3402\/jom.v3i0.5771","article-title":"Pathogenesis and treatment of oral candidosis.","volume":"3","author":"Williams","year":"2011","journal-title":"J. Oral. Microbiol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1159\/000481833","article-title":"Candida albicans and early childhood caries: a systematic review and meta-analysis.","volume":"52","author":"Xiao","year":"2018","journal-title":"Caries Res."},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002623","article-title":"The exopolysaccharide matrix modulates the interaction between 3D architecture and virulence of a mixed-species oral biofilm.","volume":"8","author":"Xiao","year":"2012","journal-title":"PLoS Pathog."},{"key":"B69","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.mib.2015.06.002","article-title":"Shaping the oral mycobiota: Interactions of opportunistic fungi with oral bacteria and the host.","volume":"27","author":"Xu","year":"2015","journal-title":"Curr. Opin. Microbiol."},{"key":"B70","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1093\/infdis\/jiw201","article-title":"Streptococcus oralis and Candida albicans synergistically activate mu-calpain to degrade E-cadherin from oral epithelial junctions.","volume":"214","author":"Xu","year":"2016","journal-title":"J. infect. Dis."},{"key":"B71","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1111\/cmi.12216","article-title":"Streptococcal co-infection augments Candida pathogenicity by amplifying the mucosal inflammatory response.","volume":"16","author":"Xu","year":"2014","journal-title":"Cell. Microbiol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1111\/omi.12223","article-title":"Antigen I\/II mediates interactions between Streptococcus mutans and Candida albicans.","volume":"33","author":"Yang","year":"2018","journal-title":"Molec. Oral. Microbiol."},{"key":"B73","doi-asserted-by":"publisher","first-page":"2320","DOI":"10.1038\/nprot.2016.132","article-title":"Large-scale production and isolation of Candida biofilm extracellular matrix.","volume":"11","author":"Zarnowski","year":"2016","journal-title":"Nat. Protoc."},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01333-14","article-title":"Novel entries in a fungal biofilm matrix encyclopedia.","volume":"5","author":"Zarnowski","year":"2014","journal-title":"mBio"},{"key":"B75","doi-asserted-by":"crossref","first-page":"25S","DOI":"10.14219\/jada.archive.2009.0355","article-title":"The biology, prevention, diagnosis and treatment of dental caries.","author":"Zero","year":"2009","journal-title":"J. Am. Dent. Assoc."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2020.00307\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T13:44:46Z","timestamp":1582897486000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2020.00307\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,28]]},"references-count":75,"alternative-id":["10.3389\/fmicb.2020.00307"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2020.00307","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,28]]},"article-number":"307"}}