{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:03:14Z","timestamp":1790352194509,"version":"4.1.0"},"reference-count":44,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T00:00:00Z","timestamp":1595894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"DOI":"10.3389\/fmicb.2020.01672","type":"journal-article","created":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T04:37:41Z","timestamp":1595911061000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":20,"title":["Clinical and Microbiological Characterization of Invasive Pulmonary Aspergillosis Caused by Aspergillus lentulus in China"],"prefix":"10.3389","volume":"11","author":[{"given":"Shu-Ying","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Na","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Lan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian-Shu","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Ting","family":"Ning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Yao","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanrong","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon C.-A.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Chun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,7,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1007\/s11046-014-9775-z","article-title":"Antifungal susceptibility profile of cryptic species of Aspergillus.","volume":"178","author":"Alastruey-Izquierdo","year":"2014","journal-title":"Mycopathologia"},{"key":"B2","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/j.ijantimicag.2011.06.005","article-title":"Three-dimensional models of 14alpha-sterol demethylase (Cyp51A) from Aspergillus lentulus and Aspergillus fumigatus: an insight into differences in voriconazole interaction.","volume":"38","author":"Alcazar-Fuoli","year":"2011","journal-title":"Int. J. Antimicrob. Agents"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.1128\/AAC.00942-07","article-title":"Aspergillus section Fumigati: antifungal susceptibility patterns and sequence-based identification.","volume":"52","author":"Alcazar-Fuoli","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"B4","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/s1130-1406(08)70058-5","article-title":"Isolation of Aspergillus lentulus in Spain from a critically ill patient with chronic obstructive pulmonary disease.","volume":"25","author":"Alhambra","year":"2008","journal-title":"Rev. Iberoam. Micol."},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-12-154","article-title":"Diversity and specificity of microsatellites within Aspergillus section fumigati.","volume":"12","author":"Araujo","year":"2012","journal-title":"BMC Microbiol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1111\/j.1469-0691.2008.02661.x","article-title":"Simple and highly discriminatory microsatellite-based multiplex PCR for Aspergillus fumigatus strain typing.","volume":"15","author":"Araujo","year":"2009","journal-title":"Clin. Microbiol. Infect."},{"key":"B7","doi-asserted-by":"publisher","first-page":"5996","DOI":"10.1128\/JCM.43.12.5996-5999.2005","article-title":"Mistaken identity: neosartorya pseudofischeri and its anamorph masquerading as Aspergillus fumigatus.","volume":"43","author":"Balajee","year":"","journal-title":"J. Clin. Microbiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1128\/EC.4.3.625-632.2005","article-title":"Aspergillus lentulus sp. nov., a new sibling species of A. fumigatus.","volume":"4","author":"Balajee","year":"","journal-title":"Eukaryot. Cell."},{"key":"B9","doi-asserted-by":"publisher","first-page":"3138","DOI":"10.1128\/JCM.01070-1079","article-title":"Molecular identification of Aspergillus species collected for the transplant-associated infection surveillance network.","volume":"47","author":"Balajee","year":"2009","journal-title":"J. Clin. Microbiol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1128\/aac.48.4.1197-1203.2004","article-title":"Aspergillus fumigatus variant with decreased susceptibility to multiple antifungals.","volume":"48","author":"Balajee","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"B11","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/s11046-014-9840-7","article-title":"Early invasive pulmonary aspergillosis in a kidney transplant recipient caused by Aspergillus lentulus: first Brazilian report.","volume":"179","author":"Bastos","year":"2015","journal-title":"Mycopathologia"},{"key":"B12","year":"2017","journal-title":"Reference Method for Broth Dilution Antifungal Susceptibility Testing of Filamentous Fungi, 3rd ed. CLSI standard M38."},{"key":"B13","year":"2018","journal-title":"Epidemiological Cutoff Values for Antifungal Susceptibility Testing. 2nd ed. CLSI supplement M59."},{"key":"B14","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1111\/myc.12960","article-title":"Defining breakthrough invasive fungal infection-Position paper of the mycoses study group education and research consortium and the European Confederation of Medical Mycology.","volume":"62","author":"Cornely","year":"2019","journal-title":"Mycoses"},{"key":"B15","doi-asserted-by":"publisher","first-page":"3090","DOI":"10.1128\/JCM.01190-13","article-title":"Isavuconazole activity against Aspergillus lentulus, Neosartorya udagawae, and Cryptococcus gattii, emerging fungal pathogens with reduced azole susceptibility.","volume":"51","author":"Datta","year":"2013","journal-title":"J. Clin. Microbiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1086\/588660","article-title":"Revised definitions of invasive fungal disease from the European Organization for research and treatment of cancer\/invasive fungal infections cooperative group and the national institute of allergy and infectious diseases mycoses Study Group (EORTC\/MSG) consensus group.","volume":"46","author":"De Pauw","year":"2008","journal-title":"Clin. Infect. Dis."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.1128\/JCM.02423-06","article-title":"Comparison of two highly discriminatory molecular fingerprinting assays for analysis of multiple Aspergillus fumigatus isolates from patients with invasive aspergillosis.","volume":"45","author":"de Valk","year":"2007","journal-title":"J. Clin. Microbiol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"2815","DOI":"10.1128\/AAC.02487-12","article-title":"Is azole resistance in Aspergillus fumigatus a problem in Spain?","volume":"57","author":"Escribano","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"key":"B19","doi-asserted-by":"publisher","first-page":"429","DOI":"10.5152\/balkanmedj.2013.8572","article-title":"A case report on Aspergillus lentulus Pneumonia.","volume":"30","author":"Gurcan","year":"2013","journal-title":"Balkan Med. J."},{"key":"B20","author":"James","year":"2011","journal-title":"Manual of Clinical Microbiology"},{"key":"B21","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1111\/myc.12324","article-title":"Multi-triazole-resistant Aspergillus fumigatus infections in Australia.","volume":"58","author":"Kidd","year":"2015","journal-title":"Mycoses"},{"key":"B22","doi-asserted-by":"publisher","first-page":"S27","DOI":"10.1080\/13693780802382244","article-title":"MLST versus microsatellites for typing Aspergillus fumigatus isolates.","volume":"47","author":"Klaassen","year":"2009","journal-title":"Med. Mycol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"5581","DOI":"10.1007\/s10661-014-3804-8","article-title":"Does fungicide application in vineyards induce resistance to medical azoles in Aspergillus species?","volume":"186","author":"Lago","year":"2014","journal-title":"Environ. Monit. Assess."},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00683","article-title":"Aspergillus fumigatus-related species in clinical practice.","volume":"7","author":"Lamoth","year":"2016","journal-title":"Front. Microbiol."},{"key":"B25","author":"Larone","year":"2005","journal-title":"Medically Important Fungi: A Guide to Identification"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.01209","article-title":"Evaluation of the bruker biotyper matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry system for identification of aspergillus species directly from growth on solid agar media.","volume":"8","author":"Li","year":"2017","journal-title":"Front. Microbiol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"5459","DOI":"10.1128\/AAC.05178-11","article-title":"Role of Aspergillus lentulus 14-alpha sterol demethylase (Cyp51A) in azole drug susceptibility.","volume":"55","author":"Mellado","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"B28","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1099\/jmm.0.005942-0","article-title":"Phenotypic and genotypic characterization of Aspergillus lentulus and Aspergillus fumigatus isolates in a patient with probable invasive aspergillosis.","volume":"58","author":"Montenegro","year":"2009","journal-title":"J. Med. Microbiol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1007\/s10096-011-1229-7","article-title":"A prospective survey of Aspergillus spp. in respiratory tract samples: prevalence, clinical impact and antifungal susceptibility.","volume":"30","author":"Mortensen","year":"2011","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"B30","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1093\/cid\/ciw326","article-title":"Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the infectious diseases society of America.","volume":"63","author":"Patterson","year":"2016","journal-title":"Clin. Infect. Dis."},{"key":"B31","doi-asserted-by":"publisher","first-page":"3707","DOI":"10.1128\/JCM.01704-14","article-title":"Genetic relatedness versus biological compatibility between Aspergillus fumigatus and related species.","volume":"52","author":"Sugui","year":"2014","journal-title":"J. Clin. Microbiol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"S10","DOI":"10.3109\/13693786.2010.501345","article-title":"Unusual Aspergillus species in patients with cystic fibrosis.","volume":"48","author":"Symoens","year":"2010","journal-title":"Med. Mycol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.jiac.2015.01.005","article-title":"Secondary metabolite profiles and antifungal drug susceptibility of Aspergillus fumigatus and closely related species, Aspergillus lentulus, Aspergillus udagawae, and Aspergillus viridinutans.","volume":"21","author":"Tamiya","year":"2015","journal-title":"J. Infect. Chemother."},{"key":"B34","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1111\/ped.13193","article-title":"Invasive pulmonary aspergillosis due to azole-resistant Aspergillus lentulus.","volume":"59","author":"Tetsuka","year":"2017","journal-title":"Pediatr. Int."},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-10-315","article-title":"Multiple-locus variable-number tandem repeat analysis for molecular typing of Aspergillus fumigatus.","volume":"10","author":"Thierry","year":"2010","journal-title":"BMC Microbiol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1111\/j.1469-0691.2009.02844.x","article-title":"Comparison of multiple typing methods for Aspergillus fumigatus.","volume":"15","author":"Vanhee","year":"2009","journal-title":"Clin. Microbiol. Infect."},{"key":"B37","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s10096-013-1951-4","article-title":"Discrimination of Aspergillus lentulus from Aspergillus fumigatus by raman spectroscopy and MALDI-TOF MS.","volume":"33","author":"Verwer","year":"2014","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1128\/JCM.00162-16","article-title":"A comprehensive evaluation of the bruker biotyper MS and Vitek MS matrix-assisted laser desorption ionization-time of flight mass spectrometry systems for identification of yeasts, part of the national china hospital invasive fungal surveillance net (CHIF-NET) Study, 2012 to 2013.","volume":"54","author":"Wang","year":"2016","journal-title":"J. Clin. Microbiol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"3952","DOI":"10.1128\/JCM.01130-12","article-title":"In vitro susceptibilities of yeast species to fluconazole and voriconazole as determined by the 2010 National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) study.","volume":"50","author":"Wang","year":"2012","journal-title":"J. Clin. Microbiol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1093\/mmy\/myx067","article-title":"Antifungal susceptibilities to amphotericin B, triazoles and echinocandins of 77 clinical isolates of cryptic Aspergillus species in multicenter surveillance in Korea.","volume":"56","author":"Won","year":"2018","journal-title":"Med. Mycol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/j.jiac.2019.02.003","article-title":"Invasive pulmonary aspergillosis due to Aspergillus lentulus in an adult patient: a case report and literature review.","volume":"25","author":"Yagi","year":"2019","journal-title":"J. Infect. Chemother."},{"key":"B42","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.jiac.2015.02.010","article-title":"Invasive pulmonary aspergillosis due to Aspergillus lentulus: successful treatment of a liver transplant patient.","volume":"21","author":"Yoshida","year":"2015","journal-title":"J. Infect. Chemother."},{"key":"B43","doi-asserted-by":"publisher","first-page":"E60","DOI":"10.1111\/j.1399-3062.2012.00779.x","article-title":"Fatal outcome after heart transplantation caused by Aspergillus lentulus.","volume":"14","author":"Zbinden","year":"2012","journal-title":"Transpl. Infect. Dis."},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01328","article-title":"Using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) complemented with selected 16S rRNA and gyrB genes sequencing to practically identify clinical important viridans Group Streptococci (VGS).","volume":"7","author":"Zhou","year":"2016","journal-title":"Front. Microbiol."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2020.01672\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,28]],"date-time":"2020-07-28T04:37:44Z","timestamp":1595911064000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmicb.2020.01672\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,28]]},"references-count":44,"alternative-id":["10.3389\/fmicb.2020.01672"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2020.01672","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,28]]},"article-number":"1672"}}