{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:18:21Z","timestamp":1787026701709,"version":"build-2736575974"},"reference-count":121,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T00:00:00Z","timestamp":1607904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>\n                    <jats:italic>Aliarcobacter butzleri<\/jats:italic>\n                    is an emerging foodborne and zoonotic pathogen that is usually transmitted via contaminated food or water.\n                    <jats:italic>A. butzleri<\/jats:italic>\n                    is not only the most prevalent\n                    <jats:italic>Aliarcobacter<\/jats:italic>\n                    species, it is also closely related to thermophilic\n                    <jats:italic>Campylobacter<\/jats:italic>\n                    , which have shown increasing resistance in recent years. Therefore, it is important to assess its resistance and virulence profiles. In this study, 45\n                    <jats:italic>Aliarcobacter butzleri<\/jats:italic>\n                    strains from water poultry farms in Thuringia, Germany, were subjected to an antimicrobial susceptibility test using the gradient strip diffusion method and whole-genome sequencing. In the phylogenetic analysis, the genomes of the German strains showed high genetic diversity. Thirty-three isolates formed 11 subgroups containing two to six strains. The antimicrobial susceptibility testing showed that 32 strains were resistant to erythromycin, 26 to doxycycline, and 20 to tetracycline, respectively. Only two strains were resistant to ciprofloxacin, while 39 strains were resistant to streptomycin. The\n                    <jats:italic>in silico<\/jats:italic>\n                    prediction of the antimicrobial resistance profiles identified a large repertoire of potential resistance mechanisms. A strong correlation between a\n                    <jats:italic>gyr<\/jats:italic>\n                    A point mutation (Thr-85-Ile) and ciprofloxacin resistance was found in 11 strains. A partial correlation was observed between the presence of the\n                    <jats:italic>bla<\/jats:italic>\n                    3 gene and ampicillin resistance.\n                    <jats:italic>In silico<\/jats:italic>\n                    virulence profiling revealed a broad spectrum of putative virulence factors, including a complete lipid A cluster in all studied genomes.\n                  <\/jats:p>","DOI":"10.3389\/fmicb.2020.617685","type":"journal-article","created":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T23:36:28Z","timestamp":1607902588000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["Antimicrobial Resistance and in silico Virulence Profiling of Aliarcobacter butzleri Strains From German Water Poultry"],"prefix":"10.3389","volume":"11","author":[{"given":"Eva","family":"M\u00fcller","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Hotzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Linde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"H\u00e4nel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Tomaso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,12,14]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1292\/jvms.11-0487","article-title":"In vitro antibacterial susceptibility of Arcobacter butzleri isolated from different sources","volume":"74","author":"Abay","year":"2012","journal-title":"J. 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