{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T16:30:18Z","timestamp":1787675418544,"version":"build-2784847793"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T00:00:00Z","timestamp":1673222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>Burn is one of the leading causes of death and disability in children worldwide, and wound infection is an excellent challenge in burn treatment. We performed a retrospective review of pediatric burn patients with wound infections to reveal their clinical data and investigate pathogens\u2019 distribution and drug resistance patterns to provide references for treatment. As a result, 330 pediatric burn patients with wound infections were identified; 65.8% (217\/330) were\u2009&amp;lt;\u20092\u2009years old. Most of the injuries were scalded and involved &amp;lt;10% total body surface area in size (TBSA), mainly causing II-degree burn and II\u2009+\u2009III-degree burn. Three hundred and fifty nine strains of pathogens were isolated, the primary pathogens were <jats:italic>Staphylococcus aureus<\/jats:italic> (45.4%) and <jats:italic>Pseudomonas aeruginosa<\/jats:italic> (18.7%). Both <jats:italic>S. aureus<\/jats:italic> and <jats:italic>P. aeruginosa<\/jats:italic> isolated from 2012 to 2016 were more likely to be multi-resistant than those isolated from 2017 to 2021, as they were significantly associated with resistance to \u22654 Clinical and Laboratory Standard Institute (CLSI) classes (<jats:italic>p<\/jats:italic>\u2009=\u20090.040 and 0.006, respectively). In conclusion, children aged &amp;lt;2\u2009years old were the main pediatric burn patients with wound infections. The primary bacteria isolated from the wound were <jats:italic>S. aureus<\/jats:italic> and <jats:italic>P. aeruginosa<\/jats:italic>, with a decreasing tendency of multi-resistance.<\/jats:p>","DOI":"10.3389\/fmicb.2022.1034099","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T12:37:38Z","timestamp":1673354258000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["The clinical characteristics and microbiological investigation of pediatric burn patients with wound infections in a tertiary hospital in Ningbo, China: A ten-year retrospective study"],"prefix":"10.3389","volume":"13","author":[{"given":"Yefang","family":"Ke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,1,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1016\/j.burns.2020.05.021","article-title":"Epidemiology and trend of us pediatric burn hospitalizations, 2003-2016","volume":"47","author":"Armstrong","year":"2021","journal-title":"Burns"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"916","DOI":"10.47391\/JPMA.1245","article-title":"Distribution and antimicrobial susceptibility profile of bacterial and fungal pathogens isolated from burn wounds in hospitalized patients","volume":"71","author":"Basit","year":"2021","journal-title":"J. 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