{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:20:01Z","timestamp":1787026801751,"version":"build-2736575974"},"reference-count":260,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T00:00:00Z","timestamp":1680739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>\n                    Gut microbiota is of great importance in human health, and its roles in the maintenance of skeletal homeostasis have long been recognized as the \u201cgut-bone axis.\u201d Recent evidence has indicated intercorrelations between gut microbiota, endocrine system and bone metabolism. This review article discussed the complex interactions between gut microbiota and bone metabolism-related hormones, including sex steroids, insulin-like growth factors, 5-hydroxytryptamine, parathyroid hormone, glucagon-like peptides, peptide YY, etc. Although the underlying mechanisms still need further investigation, the regulatory effect of gut microbiota on bone health\n                    <jats:italic>via<\/jats:italic>\n                    interplaying with endocrine system may provide a new paradigm for the better management of musculoskeletal disorders.\n                  <\/jats:p>","DOI":"10.3389\/fmicb.2023.1124945","type":"journal-article","created":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T02:32:40Z","timestamp":1680748360000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":33,"title":["The associations of gut microbiota, endocrine system and bone metabolism"],"prefix":"10.3389","volume":"14","author":[{"given":"Ye","family":"Tu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Kuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,4,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1851","DOI":"10.1210\/endo.143.5.8776","article-title":"The role of the resting zone in growth plate chondrogenesis","volume":"143","author":"Abad","year":"2002","journal-title":"Endocrinology"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"102654","DOI":"10.1016\/j.jtherbio.2020.102654","article-title":"Probiotic bacteria maintain normal growth mechanisms of heat stressed broiler chickens","volume":"92","author":"Abdelqader","year":"2020","journal-title":"J. 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