{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:18:51Z","timestamp":1792091931383,"version":"4.4.0"},"reference-count":323,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T00:00:00Z","timestamp":1736380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>A significant global health crisis is predicted to emerge due to antimicrobial resistance by 2050, with an estimated 10 million deaths annually. Increasing antibiotic resistance necessitates continuous therapeutic innovation as conventional antibiotic treatments become increasingly ineffective. The naturally occurring antibacterial, antifungal, and antiviral compounds offer a viable alternative to synthetic antibiotics. This review presents bacterial resistance mechanisms, nanocarriers for drug delivery, and plant-based compounds for nanoformulations, particularly nanoantibiotics (nAbts). Green synthesis of nanoparticles has emerged as a revolutionary approach, as it enhances the effectiveness, specificity, and transport of encapsulated antimicrobials. In addition to minimizing systemic side effects, these nanocarriers can maximize therapeutic impact by delivering the antimicrobials directly to the infection site. Furthermore, combining two or more antibiotics within these nanoparticles often exhibits synergistic effects, enhancing the effectiveness against drug-resistant bacteria. Antimicrobial agents are routinely obtained from secondary metabolites of plants, including essential oils, phenols, polyphenols, alkaloids, and others. Integrating plant-based antibacterial agents and conventional antibiotics, assisted by suitable nanocarriers for codelivery, is a potential solution for addressing bacterial resistance. In addition to increasing their effectiveness and boosting the immune system, this synergistic approach provides a safer and more effective method of tackling future bacterial infections.<\/jats:p>","DOI":"10.3389\/fmicb.2024.1391345","type":"journal-article","created":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T06:11:35Z","timestamp":1736403095000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":38,"title":["Unveiling the nanoworld of antimicrobial resistance: integrating nature and nanotechnology"],"prefix":"10.3389","volume":"15","author":[{"given":"Devesh","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakshi","family":"Gautam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakshi","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nalini","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul Mabood","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa","family":"Bisht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,1,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.3390\/antibiotics12101514","article-title":"Antibacterial and anti-efflux activities of cinnamon essential oil against pan and extensive drug-resistant Pseudomonas aeruginosa isolated from human and animal sources","volume":"12","author":"Abdelatti","year":"2023","journal-title":"Antibiotics"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"3475738","DOI":"10.1155\/2017\/3475738","article-title":"Evaluation of phenolic compounds and antioxidant and antimicrobial activities of some common herbs","volume":"2017","author":"Abdul Qadir","year":"2017","journal-title":"Int. J. Anal. Chem."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1186\/s12302-022-00684-2","article-title":"The potential activity of biosynthesized silver nanoparticles of Pseudomonas aeruginosa as an antibacterial agent against multidrug-resistant isolates from intensive care unit and anticancer agent","volume":"34","author":"Abeer Mohammed","year":"2022","journal-title":"Environ. Sci. Eur."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"98","DOI":"10.3109\/21691401.2015.1129628","article-title":"Enhanced anti-cancer and antimicrobial activities of curcumin nanoparticles","volume":"45","author":"Adahoun","year":"2016","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"15038","DOI":"10.3390\/ijms232315038","article-title":"The potential of antibiotics and nanomaterial combinations as therapeutic strategies in the management of multidrug-resistant infections: a review","volume":"23","author":"Adeniji","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.indcrop.2017.02.015","article-title":"Essential oil nanoemulsions of wild patchouli attenuate multi-drug resistant gram-positive, gram-negative and Candida albicans","volume":"100","author":"Adhavan","year":"2017","journal-title":"Ind. Crop. Prod."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"118048","DOI":"10.1016\/j.envres.2023.118048","article-title":"Benign-by-design plant extract-mediated preparation of copper oxide nanoparticles for environmentally related applications","volume":"247","author":"Ahmad","year":"2024","journal-title":"Environ. Res."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"4659","DOI":"10.3390\/molecules26154659","article-title":"Green synthesis of CeO2 nanoparticles from the Abelmoschus esculentus extract: evaluation of antioxidant, anticancer, antibacterial, and wound-healing activities","volume":"26","author":"Ahmed","year":"2021","journal-title":"Molecules"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"855","DOI":"10.3390\/antibiotics11070855","article-title":"Synergistic role of plant extracts and essential oils against multidrug resistance and gram-negative bacterial strains producing extended-spectrum","volume":"11","author":"Alam","year":"2022","journal-title":"Antibiotics"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"246","DOI":"10.3390\/plants12020246","article-title":"Composition, antibacterial efficacy, and anticancer activity of essential oil extracted from Psidium guajava (L.) leaves","volume":"12","author":"Alam","year":"2023","journal-title":"Plants"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1135614","DOI":"10.3389\/fmicb.2023.1135614","article-title":"Editorial: Emerging multidrug-resistant bacterial pathogens \u201csuperbugs\u201d: a rising public health threat","volume":"14","author":"Algammal","year":"2023","journal-title":"Front. Microbiol."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"22","DOI":"10.32725\/jab.2022.003","article-title":"Exploring the potential of Cinnamomum zeylanicum oil against drug resistant Helicobacter pylori-producing cytotoxic genes","volume":"20","author":"Ali","year":"2022","journal-title":"J. Appl. Biomed."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"716","DOI":"10.3390\/metabo13060716","article-title":"Plant secondary metabolites: the weapons for biotic stress management","volume":"13","author":"Al-Khayri","year":"2023","journal-title":"Metabolites"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1016\/j.jksus.2019.11.037","article-title":"Prevalence of catheter associated biofilm producing bacteria and their antibiotic sensitivity pattern","volume":"32","author":"Almalki","year":"2020","journal-title":"J. King Saud Univ. Sci."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1016\/j.jiph.2019.09.009","article-title":"Efficacy of anti-microbial catheters in preventing catheter associated urinary tract infections in hospitalized patients: a review on recent updates","volume":"12","author":"Al-Qahtani","year":"2019","journal-title":"J. Infect. Public Health"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1111\/iwj.13537","article-title":"Update on the role of antiseptics in the management of chronic wounds with critical colonisation and\/or biofilm","volume":"18","author":"Alves","year":"2020","journal-title":"Int. Wound J."},{"key":"ref17","doi-asserted-by":"publisher","first-page":"153472","DOI":"10.1016\/j.scitotenv.2022.153472","article-title":"Safer plant-based nanoparticles for combating antibiotic resistance in bacteria: a comprehensive review on its potential applications, recent advances, and future perspective","volume":"821","author":"Anand","year":"2022","journal-title":"Sci. Total Environ."},{"key":"ref18","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1093\/jac\/48.suppl_1.5","article-title":"Determination of minimum inhibitory concentrations","volume":"48","author":"Andrews","year":"2001","journal-title":"J. Antimicrob. Chemother."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2020\/2932434","article-title":"Synthesis of copper oxide nanoparticles using plant leaf extract of Catha edulis and its antibacterial activity","volume":"2020","author":"Andualem","year":"2020","journal-title":"J Nanotechnol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","year":"2022","journal-title":"Lancet"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"426","DOI":"10.30699\/IJP.2021.520570.2542","article-title":"The role of gene mutations (gyrA, parC) in resistance to ciprofloxacin in clinical isolates of Pseudomonas aeruginosa","volume":"16","author":"Arabameri","year":"2021","journal-title":"Iran. J. Pathol."},{"key":"ref22","doi-asserted-by":"publisher","first-page":"325","DOI":"10.33073\/pjm-2022-029","article-title":"Antimicrobial resistance, virulence factor-encoding genes, and biofilm-forming ability of community-associated uropathogenic Escherichia coli in Western Saudi Arabia","volume":"71","author":"Arafa","year":"2022","journal-title":"Pol. J. Microbiol."},{"key":"ref23","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s40097-016-0205-2","article-title":"Antibiofilm activity of biogenic copper and zinc oxide nanoparticles-antimicrobials collegiate against multiple drug resistant bacteria: a nanoscale approach","volume":"6","author":"Ashajyothi","year":"2016","journal-title":"J. Nanostructure Chem."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1038\/s41573-020-00114-z","article-title":"Natural products in drug discovery: advances and opportunities","volume":"20","author":"Atanasov","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"ref25","doi-asserted-by":"publisher","first-page":"102250","DOI":"10.1016\/j.cis.2020.102250","article-title":"Carbon nanomaterials against pathogens; the antimicrobial activity of carbon nanotubes, graphene\/graphene oxide, fullerenes, and their nanocomposites","volume":"284","author":"Azizi-Lalabadi","year":"2020","journal-title":"Adv. Colloid Interf. Sci."},{"key":"ref26","doi-asserted-by":"publisher","first-page":"171503","DOI":"10.1016\/j.jallcom.2023.171503","article-title":"Bio-inspired synthesis of silver nanoparticles and their nanocomposites for antibacterial and anticancer activity: a comparative study","volume":"966","author":"Balaji","year":"2023","journal-title":"J. Alloys Compd."},{"key":"ref27","doi-asserted-by":"publisher","first-page":"112","DOI":"10.18502\/ijm.v13i1.5501","article-title":"Antibacterial effect of carbon nanotube containing chemical compounds on drug-resistant isolates of Acinetobacter baumannii","volume":"13","author":"Banihashemi","year":"2021","journal-title":"Iran. J. Microbiol."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"2595","DOI":"10.3390\/microorganisms11102595","article-title":"Biofilms as battlefield armor for bacteria against antibiotics: challenges and combating strategies","volume":"11","author":"Bano","year":"2023","journal-title":"Microorganisms"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"1441","DOI":"10.3389\/fmicb.2018.01441","article-title":"Nano-strategies to fight multidrug resistant bacteria-\u201cA Battle of the Titans\u201d","volume":"9","author":"Baptista","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref30","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.nantod.2014.04.008","article-title":"Challenges associated with penetration of nanoparticles across cell and tissue barriers: a review of current status and future prospects","volume":"9","author":"Barua","year":"2014","journal-title":"Nano Today"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"112762","DOI":"10.1016\/j.fct.2021.112762","article-title":"Unpredictable adverse effects of herbal products","volume":"159","author":"Ba\u015faran","year":"2021","journal-title":"Food Chem. Toxicol."},{"key":"ref32","doi-asserted-by":"publisher","first-page":"6281","DOI":"10.1007\/s11033-020-05651-9","article-title":"Metallo-\u00df-lactamases: a review","volume":"47","author":"Behzadi","year":"2020","journal-title":"Mol. Biol. Rep."},{"key":"ref33","doi-asserted-by":"publisher","first-page":"363","DOI":"10.3390\/microorganisms7090363","article-title":"Horizontal gene transfer and its association with antibiotic resistance in the genus Aeromonas spp.","volume":"7","author":"Bello-L\u00f3pez","year":"2019","journal-title":"Microorganisms"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.3390\/antibiotics10111300","article-title":"Essential oil and hydrophilic antibiotic co-encapsulation in multiple lipid nanoparticles: proof of concept and in vitro activity against Pseudomonas aeruginosa","volume":"10","author":"Ben-Khalifa","year":"2021","journal-title":"Antibiotics"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"657431","DOI":"10.3389\/fmicb.2021.657431","article-title":"Antimicrobial activity of nanoconjugated glycopeptide antibiotics and their effect on Staphylococcus aureus biofilm","volume":"12","author":"Berini","year":"2021","journal-title":"Front. Microbiol."},{"key":"ref36","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1177\/039463200501800407","article-title":"Iron availability influences aggregation, biofilm, adhesion and invasion of Pseudomonas aeruginosa and Burkholderia cenocepacia","volume":"18","author":"Berlutti","year":"2005","journal-title":"Int. J. Immunopathol. Pharmacol."},{"key":"ref37","doi-asserted-by":"publisher","first-page":"246012","DOI":"10.1155\/2015\/246012","article-title":"Alternative antimicrobial approach: nano-antimicrobial materials","volume":"2015","author":"Beyth","year":"2015","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"ref38","doi-asserted-by":"publisher","first-page":"613077","DOI":"10.3389\/fmicb.2021.613077","article-title":"Antibacterial properties of organosulfur compounds of garlic (Allium sativum)","volume":"12","author":"Bhatwalkar","year":"2021","journal-title":"Front. Microbiol."},{"key":"ref39","doi-asserted-by":"publisher","first-page":"4713","DOI":"10.1002\/smll.201600294","article-title":"Programmed bacteria death induced by carbon dots with different surface charge","volume":"12","author":"Bing","year":"2016","journal-title":"Small"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1162941","DOI":"10.3389\/frabi.2023.1162941","article-title":"Nanotherapeutic delivery of antibiotic cocktail enhances intra-macrophage killing of Mycobacterium marinum","volume":"2","author":"Binnebose","year":"2023","journal-title":"Front. Antibiot."},{"key":"ref41","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1038\/nrmicro3380","article-title":"Molecular mechanisms of antibiotic resistance","volume":"13","author":"Blair","year":"2014","journal-title":"Nat. Rev. Microbiol."},{"key":"ref42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2147\/IJN.S52634","article-title":"Nanotechnology-based drug delivery systems and herbal medicines: a review","volume":"9","author":"Bonif\u00e1cio","year":"2013","journal-title":"Int. J. Nanomedicine"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"6867","DOI":"10.1039\/D0BM00788A","article-title":"Design of nanoengineered antibacterial polymers for biomedical applications","volume":"8","author":"Borjihan","year":"2020","journal-title":"Biomater. Sci."},{"key":"ref44","doi-asserted-by":"publisher","first-page":"829","DOI":"10.3389\/fmicb.2019.00829","article-title":"Antibacterial properties of polyphenols: characterization and QSAR (quantitative structure-activity relationship) models","volume":"10","author":"Bouarab-Chibane","year":"2019","journal-title":"Front. Microbiol."},{"key":"ref45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1086\/595011","article-title":"Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America","volume":"48","author":"Boucher","year":"2009","journal-title":"Clin. Infect. Dis."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.yrtph.2015.06.001","article-title":"Comparative assessment of nanomaterial definitions and safety evaluation considerations","volume":"73","author":"Boverhof","year":"2015","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"ref47","doi-asserted-by":"publisher","first-page":"2179","DOI":"10.3390\/nano12132179","article-title":"Nanoparticle-enabled combination therapy showed superior activity against multi-drug resistant bacterial pathogens in comparison to free drugs","volume":"12","author":"Brar","year":"2022","journal-title":"Nanomaterials"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"100099","DOI":"10.1016\/j.prmcm.2022.100099","article-title":"Traditional Chinese medicine-associated nephrotoxicity and the importance of herbal interactions\u2014an overview","volume":"3","author":"Britza","year":"2022","journal-title":"Pharmacol. Res. Mod. Chin. Med."},{"key":"ref49","doi-asserted-by":"publisher","first-page":"2768","DOI":"10.1128\/AEM.06513-11","article-title":"Nanoparticles functionalized with ampicillin destroy multiple-antibiotic-resistant isolates of Pseudomonas aeruginosa and Enterobacter aerogenes and methicillin-resistant Staphylococcus aureus","volume":"78","author":"Brown","year":"2012","journal-title":"Appl. Environ. Microbiol."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"a025247","DOI":"10.1101\/cshperspect.a025247","article-title":"\u03b2-lactams and \u03b2-lactamase inhibitors: an overview","volume":"6","author":"Bush","year":"2016","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"ref51","doi-asserted-by":"publisher","first-page":"100175","DOI":"10.1016\/j.crmicr.2022.100175","article-title":"Biofilm-forming microorganisms causing hospital-acquired infections from intravenous catheter: a systematic review","volume":"3","author":"Cangui-Panchi","year":"2022","journal-title":"Curr. Res. Microb. Sci."},{"key":"ref52","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.jcf.2015.03.003","article-title":"Inflammation in cystic fibrosis lung disease: pathogenesis and therapy","volume":"14","author":"Cantin","year":"2015","journal-title":"J. Cyst. Fibros."},{"key":"ref53","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1186\/s12951-022-01573-9","article-title":"Nanobiotics against antimicrobial resistance: harnessing the power of nanoscale materials and technologies","volume":"20","author":"Chakraborty","year":"2022","journal-title":"J. Nanobiotechnology"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1186\/s13020-021-00472-9","article-title":"The toxicology and detoxification of aconitum: traditional and modern views","volume":"16","author":"Chan","year":"2021","journal-title":"Chin. Med."},{"key":"ref55","doi-asserted-by":"publisher","first-page":"57","DOI":"10.4103\/phrev.phrev_21_17","article-title":"Developing new antimicrobial therapies: are synergistic combinations of plant extracts\/compounds with conventional antibiotics the solution?","volume":"11","author":"Cheesman","year":"2017","journal-title":"Pharmacogn. Rev."},{"key":"ref56","doi-asserted-by":"publisher","first-page":"e0153468","DOI":"10.1371\/journal.pone.0153468","article-title":"Baicalein inhibits Staphylococcus aureus biofilm formation and the quorum sensing system in vitro","volume":"11","author":"Chen","year":"2016","journal-title":"PLoS One"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"18488","DOI":"10.3390\/ijms140918488","article-title":"Novel strategies for the prevention and treatment of biofilm related infections","volume":"14","author":"Chen","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"ref58","doi-asserted-by":"publisher","first-page":"1934578X221106904","DOI":"10.1177\/1934578X221106904","article-title":"Nanomaterials: potential broad spectrum antimicrobial agents","volume":"18","author":"Chidre","year":"2023","journal-title":"Nat. Prod. Commun."},{"key":"ref59","doi-asserted-by":"publisher","first-page":"874742","DOI":"10.3389\/fbioe.2022.874742","article-title":"Green metallic nanoparticles: biosynthesis to applications","volume":"10","author":"Chopra","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"key":"ref60","doi-asserted-by":"publisher","first-page":"58","DOI":"10.3390\/medicines4030058","article-title":"Antimicrobial activity of some essential oils-present status and future perspectives","volume":"4","author":"Chouhan","year":"2017","journal-title":"Medicines"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.lwt.2019.03.012","article-title":"Antimicrobial activity and chemical stability of cinnamon oil in oil-in-water nanoemulsions fabricated using the phase inversion temperature method","volume":"110","author":"Chuesiang","year":"2019","journal-title":"LWT"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1007\/s00253-024-13057-x","article-title":"Olive oil nanoemulsion containing curcumin: antimicrobial agent against multidrug-resistant bacteria","volume":"108","author":"Confessor","year":"2024","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref63","doi-asserted-by":"publisher","first-page":"2327","DOI":"10.1016\/j.biomaterials.2011.11.057","article-title":"The molecular mechanism of action of bactericidal gold nanoparticles on Escherichia coli","volume":"33","author":"Cui","year":"2011","journal-title":"Biomaterials"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"2641","DOI":"10.1007\/s42770-023-01102-2","article-title":"Biogenic silver nanoparticles: in vitro activity against Staphylococcus aureus methicillin-resistant (MRSA) and multidrug-resistant coagulase-negative Staphylococcus (CoNS)","volume":"54","author":"da Cunha","year":"2023","journal-title":"Braz. J. Microbiol."},{"key":"ref65","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.micpath.2018.03.043","article-title":"Nanoemulsions containing Cymbopogon flexuosus essential oil: development, characterization, stability study and evaluation of antimicrobial and antibiofilm activities","volume":"118","author":"da Silva G\u00fcndel","year":"","journal-title":"Microb. Pathog."},{"key":"ref66","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1016\/j.jddst.2018.05.038","article-title":"Basil oil-nanoemulsions: development, cytotoxicity and evaluation of antioxidant and antimicrobial potential","volume":"46","author":"da Silva G\u00fcndel","year":"","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref67","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1016\/j.ijporl.2012.06.013","article-title":"Bacterial involvement in otitis media with effusion","volume":"76","author":"Daniel","year":"2012","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"ref68","doi-asserted-by":"publisher","first-page":"117339","DOI":"10.1016\/j.carbpol.2020.117339","article-title":"Eugenol loaded chitosan nanoemulsion for food protection and inhibition of aflatoxin B1 synthesizing genes based on molecular docking","volume":"255","author":"Das","year":"2021","journal-title":"Carbohydr. Polym."},{"key":"ref69","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/B978-0-12-815846-3.00019-3","article-title":"Chapter 19\u2014toxic herbals and plants in the United States","volume-title":"Toxicology cases for the clinical and forensic laboratory","author":"Dasgupta","year":"2020"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"209","DOI":"10.33073\/pjm-2023-005","article-title":"Antimicrobial resistance and biofilm formation of Staphylococcus aureus isolates from febrile cases: findings from a rural cohort of Odisha, India","volume":"72","author":"Dash","year":"2023","journal-title":"Pol. J. Microbiol."},{"key":"ref71","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1039\/c8na00413g","article-title":"Graphene oxide prevents mycobacteria entry into macrophages through extracellular entrapment","volume":"1","author":"De Maio","year":"2019","journal-title":"Nanoscale Adv."},{"key":"ref72","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.3390\/nano10081431","article-title":"Graphene oxide-linezolid combination as potential new anti-tuberculosis treatment","volume":"10","author":"De Maio","year":"2020","journal-title":"Nanomaterials"},{"key":"ref73","doi-asserted-by":"publisher","first-page":"644564","DOI":"10.3389\/fnano.2021.644564","article-title":"Drug delivery with carbon-based nanomaterials as versatile nanocarriers: progress and prospects","volume":"3","author":"Debnath","year":"2021","journal-title":"Front. Nanotechnol."},{"key":"ref74","first-page":"20","article-title":"Antibacterial activity of anthraquinone encapsulated chitosan\/poly (lactic acid) nanoparticles","volume":"5","author":"Dhanapal","year":"2014","journal-title":"Int. J. Pharma Bio Sci."},{"key":"ref75","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.3390\/ijms24021004","article-title":"Biofilms in chronic wound infections: innovative antimicrobial approaches using the in vitro Lubbock chronic wound biofilm model","volume":"24","author":"Diban","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"ref76","doi-asserted-by":"publisher","first-page":"7291","DOI":"10.2147\/IJN.S146315","article-title":"Effective use of nanocarriers as drug delivery systems for the treatment of selected tumors","volume":"12","author":"Din","year":"2017","journal-title":"Int. J. Nanomedicine"},{"key":"ref77","doi-asserted-by":"publisher","first-page":"23899","DOI":"10.1039\/D0RA04926C","article-title":"Green synthesis of ZnO nanoparticles using orange fruit peel extract for antibacterial activities","volume":"10","author":"Doan Thi","year":"2020","journal-title":"RSC Adv."},{"key":"ref78","doi-asserted-by":"publisher","first-page":"6910","DOI":"10.3390\/molecules28196910","article-title":"Thymus vulgaris oil nanoemulsion: synthesis, characterization, antimicrobial and anticancer activities","volume":"28","author":"Doghish","year":"2023","journal-title":"Molecules"},{"key":"ref79","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/14786419.2024.2301741","article-title":"Multifactorial action of lavender and lavandin oils against filamentous fungi","author":"Donadu","year":"2024","journal-title":"Nat. Prod. Res."},{"key":"ref80","doi-asserted-by":"publisher","first-page":"277","DOI":"10.3201\/eid0702.010226","article-title":"Biofilms and device-associated infections","volume":"7","author":"Donlan","year":"2001","journal-title":"Emerg. Infect. Dis."},{"key":"ref81","doi-asserted-by":"publisher","first-page":"125","DOI":"10.3897\/pharmacia.69.e77608","article-title":"Effect of gold nanoparticles on the expression of efflux pump mexA and mexB genes of Pseudomonas aeruginosa strains by quantitative real-time PCR","volume":"69","author":"Dorri","year":"2022","journal-title":"Pharmacia"},{"key":"ref82","doi-asserted-by":"publisher","first-page":"e9419","DOI":"10.7717\/peerj.9419","article-title":"Biofilm modelling on the contact lenses and comparison of the in vitro activities of multipurpose lens solutions and antibiotics","volume":"8","author":"Dosler","year":"2020","journal-title":"PeerJ"},{"key":"ref83","doi-asserted-by":"publisher","first-page":"5706","DOI":"10.1002\/adma.201302627","article-title":"Enhanced efficacy of superparamagnetic iron oxide nanoparticles against antibiotic-resistant biofilms in the presence of metabolites","volume":"25","author":"Durmus","year":"2013","journal-title":"Adv. Mater."},{"key":"ref84","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/s40580-016-0085-7","article-title":"Design, challenge, and promise of stimuli-responsive nanoantibiotics","volume":"3","author":"Edson","year":"2016","journal-title":"Nano Converg."},{"key":"ref85","doi-asserted-by":"publisher","first-page":"e65301","DOI":"10.3791\/65301","article-title":"Swine model of biofilm infection and invisible wounds","volume":"196","author":"El Masry","year":"2023","journal-title":"J. Vis. Exp."},{"key":"ref86","doi-asserted-by":"publisher","first-page":"604","DOI":"10.3390\/membranes13060604","article-title":"Nano-chitosan\/eucalyptus oil\/cellulose acetate nanofibers: manufacturing, antibacterial and wound healing activities","volume":"13","author":"Elbhnsawi","year":"2023","journal-title":"Membranes"},{"key":"ref87","doi-asserted-by":"publisher","first-page":"142","DOI":"10.3390\/pharmaceutics12020142","article-title":"Nanomedicine fight against antibacterial resistance: an overview of the recent pharmaceutical innovations","volume":"12","author":"Eleraky","year":"2020","journal-title":"Pharmaceutics"},{"key":"ref88","doi-asserted-by":"publisher","first-page":"102459","DOI":"10.1016\/j.jddst.2021.102459","article-title":"An overview on natural product drug formulations from conventional medicines to nanomedicines: past, present and future","volume":"63","author":"Elkordy","year":"2021","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref89","doi-asserted-by":"publisher","first-page":"5145","DOI":"10.1016\/j.sjbs.2021.05.033","article-title":"Using essential oils to overcome bacterial biofilm formation and their antimicrobial resistance","volume":"28","author":"El-Tarabily","year":"2021","journal-title":"Saudi J. Biol. Sci."},{"key":"ref90","doi-asserted-by":"publisher","first-page":"17917","DOI":"10.1007\/s11356-015-5018-1","article-title":"The short-term toxic effects of TiO2 nanoparticles toward bacteria through viability, cellular respiration, and lipid peroxidation","volume":"22","author":"Erdem","year":"2015","journal-title":"Environ. Sci. Pollut. Res."},{"key":"ref91","doi-asserted-by":"publisher","first-page":"479","DOI":"10.15171\/apb.2017.058","article-title":"Vancomycin capped with silver nanoparticles as an antibacterial agent against multi-drug resistance bacteria","volume":"7","author":"Esmaeillou","year":"2017","journal-title":"Adv. Pharm Bull."},{"key":"ref92","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.ijantimicag.2011.05.005","article-title":"Essential oils from Moroccan plants as potential chemosensitisers restoring antibiotic activity in resistant gram-negative bacteria","volume":"38","author":"Fadli","year":"2011","journal-title":"Int. J. Antimicrob. Agents"},{"key":"ref93","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.cnur.2020.06.015","article-title":"Clinical aromatherapy","volume":"55","author":"Farrar","year":"2020","journal-title":"Nurs. Clin. North Am."},{"key":"ref94","doi-asserted-by":"publisher","first-page":"10472","DOI":"10.1002\/anie.201201114","article-title":"Multivalency as a chemical organization and action principle","volume":"51","author":"Fasting","year":"2012","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"ref95","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1111\/lam.12886","article-title":"Solid lipid nanoparticles (SLN) carrying Eugenia caryophyllata essential oil: the novel nanoparticulate systems with broad-spectrum antimicrobial activity","volume":"66","author":"Fazly Bazzaz","year":"2018","journal-title":"Lett. Appl. Microbiol."},{"key":"ref1002","doi-asserted-by":"publisher","first-page":"44720","DOI":"10.1021\/acsomega.2c04042","article-title":"Synthesis of Nickel Oxide Nanoparticles and Copper-Doped Nickel Oxide Nanocomposites Using Phytolacca dodecandra L\u2019Herit Leaf Extract and Evaluation of Its Antioxidant and Photocatalytic Activities","volume":"7","author":"Firisa","year":"2022","journal-title":"ACS omega."},{"key":"ref96","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.jconrel.2015.01.037","article-title":"Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity","volume":"202","author":"Fisher","year":"2015","journal-title":"J. Control. Release"},{"key":"ref97","doi-asserted-by":"publisher","first-page":"13145","DOI":"10.1038\/s41598-020-70211-x","article-title":"Comparable antibacterial effects and action mechanisms of silver and iron oxide nanoparticles on Escherichia coli and Salmonella typhimurium","volume":"10","author":"Gabrielyan","year":"2020","journal-title":"Sci. Rep."},{"key":"ref98","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1021\/cr100109t","article-title":"Quorum sensing in gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways","volume":"111","author":"Galloway","year":"2010","journal-title":"Chem. Rev."},{"key":"ref99","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1038\/s41579-020-00469-5","article-title":"Nanomaterials arising amid antibiotic resistance","volume":"19","author":"Gao","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"ref100","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3109\/17453674.2014.966290","article-title":"The role of microbial biofilms in prosthetic joint infections","volume":"86","author":"Gbejuade","year":"2014","journal-title":"Acta Orthop."},{"key":"ref101","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.3390\/nano11051075","article-title":"Nanobiosystems for antimicrobial drug-resistant infections","volume":"11","author":"Gkartziou","year":"2021","journal-title":"Nanomaterials"},{"key":"ref102","doi-asserted-by":"publisher","first-page":"1700033","DOI":"10.1002\/adtp.201700033","article-title":"Antimicrobial activity of metal and metal-oxide based nanoparticles","volume":"1","author":"Gold","year":"2018","journal-title":"Adv. Ther."},{"key":"ref103","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1111\/apm.12665","article-title":"Central venous catheters and biofilms: where do we stand in 2017?","volume":"125","author":"Gominet","year":"2017","journal-title":"APMIS"},{"key":"ref104","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1186\/s40001-023-01121-7","article-title":"Biofilm and wound healing: from bench to bedside","volume":"28","author":"Goswami","year":"2023","journal-title":"Eur. J. Med. Res."},{"key":"ref105","doi-asserted-by":"publisher","first-page":"923","DOI":"10.3390\/antiox9100923","article-title":"Role of the encapsulation in bioavailability of phenolic compounds","volume":"9","author":"Grgi\u0107","year":"2020","journal-title":"Antioxidants"},{"key":"ref106","doi-asserted-by":"publisher","first-page":"015004","DOI":"10.1088\/2399-1984\/aa69fb","article-title":"Synergistic antimicrobial therapy using nanoparticles and antibiotics for the treatment of multidrug-resistant bacterial infection","volume":"1","author":"Gupta","year":"2017","journal-title":"Nano Futures"},{"key":"ref107","doi-asserted-by":"publisher","first-page":"119736","DOI":"10.1016\/j.carbpol.2022.119736","article-title":"Linezolid nanoAntiobiotics and SERS-nanoTags based on polymeric cyclodextrin bimetallic core-shell nanoarchitectures","volume":"293","author":"Hada","year":"2022","journal-title":"Carbohydr. Polym."},{"key":"ref108","doi-asserted-by":"publisher","first-page":"101560","DOI":"10.1016\/j.jksus.2021.101560","article-title":"Gold nanoparticles: synthesis properties and applications","volume":"33","author":"Hammami","year":"2021","journal-title":"J. King Saud Univ. Sci."},{"key":"ref109","doi-asserted-by":"publisher","first-page":"2321","DOI":"10.2147\/IDR.S177247","article-title":"Health care-associated infections\u2014an overview","volume":"11","author":"Haque","year":"2018","journal-title":"Infect. Drug Resist."},{"key":"ref110","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1016\/j.colsurfb.2018.09.018","article-title":"Diminishing biofilm resistance to antimicrobial nanomaterials through electrolyte screening of electrostatic interactions","volume":"173","author":"Harper","year":"2018","journal-title":"Colloids Surf. B"},{"key":"ref111","doi-asserted-by":"publisher","first-page":"100831","DOI":"10.1016\/j.nmni.2020.100831","article-title":"Study of biofilm formation, structure and antibiotic resistance in Staphylococcus saprophyticus strains causing urinary tract infection in women in Ahvaz, Iran","volume":"39","author":"Hashemzadeh","year":"2020","journal-title":"New Microbes New Infect."},{"key":"ref112","doi-asserted-by":"publisher","first-page":"e26893","DOI":"10.7759\/cureus.26893","article-title":"Clinical implications of herbal supplements in conventional medical practice: a US perspective","volume":"14","author":"Hassen","year":"2022","journal-title":"Cureus"},{"key":"ref113","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.3390\/nano9081162","article-title":"Carvacrol loaded solid lipid nanoparticles of propylene glycol monopalmitate and glyceryl monostearate: preparation, characterization, and synergistic antimicrobial activity","volume":"9","author":"He","year":"2019","journal-title":"Nanomaterials"},{"key":"ref114","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.phymed.2008.06.008","article-title":"Synergism between natural products and antibiotics against infectious diseases","volume":"15","author":"Hemaiswarya","year":"2008","journal-title":"Phytomedicine"},{"key":"ref115","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11020413","article-title":"Nanotechnology as a promising approach to combat multidrug resistant bacteria: a comprehensive review and future perspectives","volume":"11","author":"Hetta","year":"2023","journal-title":"Biomedicines"},{"key":"ref116","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/S1569-1993(02)00104-2","article-title":"Understanding bacterial biofilms in patients with cystic fibrosis: current and innovative approaches to potential therapies","volume":"1","author":"H\u00f8iby","year":"2002","journal-title":"J. Cyst. Fibros."},{"key":"ref117","doi-asserted-by":"publisher","first-page":"e113104","DOI":"10.1371\/journal.pone.0113104","article-title":"Searching for synergistic bronchodilators and novel therapeutic regimens for chronic lung diseases from a traditional Chinese medicine, Qingfei Xiaoyan Wan","volume":"9","author":"Hou","year":"2014","journal-title":"PLoS One"},{"key":"ref118","doi-asserted-by":"publisher","first-page":"e0063423","DOI":"10.1128\/spectrum.00634-23","article-title":"Tigecycline resistance-associated mutations in the MepA efflux pump in Staphylococcus aureus","volume":"11","author":"Huang","year":"2023","journal-title":"Microbiol Spectr"},{"key":"ref119","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.jconrel.2011.07.002","article-title":"\u201cNanoantibiotics\u201d: a new paradigm for treating infectious diseases using nanomaterials in the antibiotics resistant era","volume":"156","author":"Huh","year":"2011","journal-title":"J. Control. Release"},{"key":"ref120","doi-asserted-by":"publisher","first-page":"2648","DOI":"10.3390\/polym14132648","article-title":"Nanocellulose-based composite materials used in drug delivery systems","volume":"14","author":"Huo","year":"2022","journal-title":"Polymers"},{"key":"ref121","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.ijpharm.2019.05.061","article-title":"Solidified SNEDDS for the oral delivery of rifampicin: evaluation, proof of concept, in vivo kinetics, and in silico GastroPlusTM simulation","volume":"566","author":"Hussain","year":"2019","journal-title":"Int. J. Pharm."},{"key":"ref122","doi-asserted-by":"publisher","first-page":"2130","DOI":"10.3390\/nano11082130","article-title":"Green synthesis of nanomaterials","volume":"11","author":"Huston","year":"2021","journal-title":"Nanomaterials"},{"key":"ref123","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.3389\/fphar.2019.01483","article-title":"Use of herbal medicine by pregnant women: what physicians need to know","volume":"10","author":"Illamola","year":"2020","journal-title":"Front. Pharmacol."},{"key":"ref124","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1007\/s00253-013-5422-8","article-title":"Bioactivity, mechanism of action, and cytotoxicity of copper-based nanoparticles: a review","volume":"98","author":"Ingle","year":"2013","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref125","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.2174\/1381612825999190619130216","article-title":"Antimicrobial agents and urinary tract infections","volume":"25","author":"Issakhanian","year":"2019","journal-title":"Curr. Pharm. Des."},{"key":"ref126","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1007\/s10311-020-01074-x","article-title":"Green synthesis of nanoparticles using plant extracts: a review","volume":"19","author":"Jadoun","year":"2021","journal-title":"Environ. Chem. Lett."},{"key":"ref127","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.3389\/fmicb.2016.01580","article-title":"Encapsulation of cardamom essential oil in chitosan nano-composites: in-vitro efficacy on antibiotic resistant bacterial pathogens and cytotoxicity studies","volume":"7","author":"Jamil","year":"2016","journal-title":"Front. Microbiol."},{"key":"ref128","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1186\/s12951-020-00704-4","article-title":"Role of capping agents in the application of nanoparticles in biomedicine and environmental remediation: recent trends and future prospects","volume":"18","author":"Javed","year":"2020","journal-title":"J. Nanobiotechnology"},{"key":"ref129","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.jconrel.2019.06.013","article-title":"Nanoparticle-drug conjugates treating bacterial infections","volume":"307","author":"Jelinkova","year":"2019","journal-title":"J. Control. Release"},{"key":"ref130","doi-asserted-by":"publisher","first-page":"306","DOI":"10.2174\/1567201819666220511120215","article-title":"Intracellular activity of poly (DL-lactide-co-glycolide) nanoparticles encapsulated with prothionamide, pyrazinamide, levofloxacin, linezolid, or ethambutol on multidrug-resistant Mycobacterium tuberculosis","volume":"20","author":"Jiang","year":"2023","journal-title":"Curr. Drug Deliv."},{"key":"ref131","doi-asserted-by":"publisher","first-page":"83","DOI":"10.3390\/pr11010083","article-title":"Current trends in toxicity assessment of herbal medicines: a narrative review","volume":"11","author":"Jitareanu","year":"2022","journal-title":"Processes"},{"key":"ref132","doi-asserted-by":"publisher","first-page":"391","DOI":"10.3390\/antibiotics9070391","article-title":"Antimicrobial spectrum of Titroleane\u2122:a new potent anti-infective agent","volume":"9","author":"Johansen","year":"2020","journal-title":"Antibiotics"},{"key":"ref133","first-page":"229","article-title":"A perspective on the Phytopharmaceuticals responsible for the therapeutic applications","volume-title":"Recent advances in drug delivery technology","author":"Joshi","year":"2016"},{"key":"ref134","doi-asserted-by":"publisher","first-page":"e05992020","DOI":"10.1590\/0037-8682-0599-2020","article-title":"Role of aminoglycoside-modifying enzymes and 16S rRNA methylase (ArmA) in resistance of Acinetobacter baumannii clinical isolates against aminoglycosides","volume":"54","author":"Jouybari","year":"2021","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"ref135","doi-asserted-by":"publisher","first-page":"2840","DOI":"10.2166\/wst.2023.150","article-title":"Pharmacological assessment of Co3O4, CuO, NiO and ZnO nanoparticles via antibacterial, anti-biofilm and anti-quorum sensing activities","volume":"87","author":"Junejo","year":"2023","journal-title":"Water Sci. Technol."},{"key":"ref136","doi-asserted-by":"publisher","first-page":"128379","DOI":"10.1016\/j.molstruc.2020.128379","article-title":"Green synthesis of hierarchical copper oxide microleaf bundles using Hibiscus cannabinus leaf extract for antibacterial application","volume":"1217","author":"Kalaiyan","year":"2020","journal-title":"J. Mol. Struct."},{"key":"ref137","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.3390\/ma11091705","article-title":"Targeting the bacterial protective armour; challenges and novel strategies in the treatment of microbial biofilm","volume":"11","author":"Kamaruzzaman","year":"2018","journal-title":"Materials"},{"key":"ref138","doi-asserted-by":"publisher","first-page":"300","DOI":"10.4103\/joacp.JOACP_349_15","article-title":"Action and resistance mechanisms of antibiotics: a guide for clinicians","volume":"33","author":"Kapoor","year":"2017","journal-title":"J. Anaesthesiol. Clin. Pharmacol."},{"key":"ref139","doi-asserted-by":"publisher","first-page":"234","DOI":"10.3390\/antibiotics12020234","article-title":"Carbapenem-resistant Klebsiella pneumoniae: virulence factors, molecular epidemiology and latest updates in treatment options","volume":"12","author":"Karampatakis","year":"2023","journal-title":"Antibiotics"},{"key":"ref140","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3390\/antibiotics13030257","article-title":"Pan-genome plasticity and virulence factors: a natural treasure trove for Acinetobacter baumannii","volume":"13","author":"Karampatakis","year":"2024","journal-title":"Antibiotic"},{"key":"ref141","doi-asserted-by":"publisher","first-page":"17","DOI":"10.4103\/JLP.JLP_98_18","article-title":"Detection of biofilm among uropathogenic Escherichia coli and its correlation with antibiotic resistance pattern","volume":"11","author":"Karigoudar","year":"2019","journal-title":"J. Lab. Physicians"},{"key":"ref142","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/B978-0-323-95715-1.00008-X","article-title":"Biofilm formation in acute and chronic respiratory infections caused by nosocomial gram-negative bacteria","volume-title":"Microbial biofilms","author":"Karmakar","year":"2023"},{"key":"ref143","doi-asserted-by":"publisher","first-page":"13492","DOI":"10.1021\/acsomega.3c00110","article-title":"Perspectives on usage of functional nanomaterials in antimicrobial therapy for antibiotic-resistant bacterial infections","volume":"8","author":"Karnwal","year":"2023","journal-title":"ACS Omega"},{"key":"ref144","doi-asserted-by":"publisher","first-page":"128869","DOI":"10.1016\/j.ijbiomac.2023.128869","article-title":"Green synthesis of MnO2 nanoparticles from Psidium guajava leaf extract: morphological characterization, photocatalytic and DNA\/BSA interaction studies","volume":"258","author":"Karthik","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"ref145","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1186\/s12879-020-05186-1","article-title":"Biofilm formation, antimicrobial susceptibility and virulence genes of Uropathogenic Escherichia coli isolated from clinical isolates in Uganda","volume":"20","author":"Katongole","year":"2020","journal-title":"BMC Infect. Dis."},{"key":"ref146","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1080\/10826068.2020.1815057","article-title":"Zinc oxide nanoparticles inhibit bacterial biofilm formation via altering cell membrane permeability","volume":"51","author":"Kaur","year":"2020","journal-title":"Prep. Biochem. Biotechnol."},{"key":"ref147","doi-asserted-by":"publisher","first-page":"327","DOI":"10.17265\/2328-2150\/2019.06.007","article-title":"Green synthesis of CuO nanoparticles using leaf extract of Catha edulis and its antibacterial activity","volume":"7","author":"Kelele","year":"2019","journal-title":"J. Pharm. Pharmacol."},{"key":"ref148","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1186\/s12866-017-1012-8","article-title":"Structure, genetics and worldwide spread of New Delhi Metallo-\u03b2-lactamase (NDM): a threat to public health","volume":"17","author":"Khan","year":"2017","journal-title":"BMC Microbiol."},{"key":"ref149","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/j.arabjc.2017.05.011","article-title":"Nanoparticles: properties, applications and toxicities","volume":"12","author":"Khan","year":"2019","journal-title":"Arab. J. Chem."},{"key":"ref150","doi-asserted-by":"publisher","first-page":"835","DOI":"10.3390\/biom10060835","article-title":"Green synthesis of gold and silver nanoparticles using leaf extract of Clerodendrum inerme; characterization, antimicrobial, and antioxidant activities","volume":"10","author":"Khan","year":"2020","journal-title":"Biomol. Ther."},{"key":"ref151","doi-asserted-by":"publisher","first-page":"2709","DOI":"10.2217\/nnm.15.108","article-title":"Reactive oxygen species-activated nanomaterials as theranostic agents","volume":"10","author":"Kim","year":"2015","journal-title":"Nanomedicine"},{"key":"ref152","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1038\/s41565-021-00866-8","article-title":"Nanotechnology approaches for global infectious diseases","volume":"16","author":"Kirtane","year":"2021","journal-title":"Nat. Nanotechnol."},{"key":"ref153","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1038\/nrmicro2333","article-title":"How antibiotics kill bacteria: from targets to networks","volume":"8","author":"Kohanski","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"ref154","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s40463-020-00418-5","article-title":"Bacterial aetiology of chronic otitis media with effusion in children\u2014risk factors","volume":"49","author":"Korona-Glowniak","year":"2020","journal-title":"J. Otolaryngol. Head Neck Surg."},{"key":"ref155","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.nano.2014.09.004","article-title":"Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent","volume":"11","author":"Krausz","year":"2015","journal-title":"Nanomedicine"},{"key":"ref156","doi-asserted-by":"publisher","first-page":"431","DOI":"10.3390\/pharmaceutics12050431","article-title":"Encapsulation of essential oils via nanoprecipitation process: overview, progress, challenges and prospects","volume":"12","author":"Lammari","year":"2020","journal-title":"Pharmaceutics"},{"key":"ref157","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.lwt.2019.02.061","article-title":"Antibacterial and antioxidant properties of hydroxypropyl methylcellulose-based active composite films incorporating oregano essential oil nanoemulsions","volume":"106","author":"Lee","year":"2019","journal-title":"LWT"},{"key":"ref158","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.3389\/fphar.2019.01153","article-title":"Nanoparticles in the treatment of infections caused by multidrug-resistant organisms","volume":"10","author":"Lee","year":"2019","journal-title":"Front. Pharmacol."},{"key":"ref159","doi-asserted-by":"publisher","first-page":"6278","DOI":"10.1039\/d3na00530e","article-title":"Recent advances in nanoantibiotics against multidrug-resistant bacteria","volume":"5","author":"Li","year":"2023","journal-title":"Nanoscale Adv."},{"key":"ref160","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1002\/adhm.201500712","article-title":"Toward a molecular understanding of the antibacterial mechanism of copper-bearing titanium alloys against Staphylococcus aureus","volume":"5","author":"Li","year":"","journal-title":"Adv. Healthc. Mater."},{"key":"ref161","doi-asserted-by":"publisher","first-page":"627","DOI":"10.3109\/10717544.2014.880756","article-title":"Liposomal co-delivery of daptomycin and clarithromycin at an optimized ratio for treatment of methicillin-resistant Staphylococcus aureus infection","volume":"22","author":"Li","year":"2015","journal-title":"Drug Deliv."},{"key":"ref162","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.3390\/ijms241411680","article-title":"Bacterial biofilm formation on biomaterials and approaches to its treatment and prevention","volume":"24","author":"Li","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"ref163","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.colsurfb.2016.02.017","article-title":"Tea tree oil nanoemulsions for inhalation therapies of bacterial and fungal pneumonia","volume":"141","author":"Li","year":"","journal-title":"Colloids Surf. B"},{"key":"ref164","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/j.colsurfb.2018.08.069","article-title":"Cellulose acetate\u2014essential oil nanocapsules with antimicrobial activity for biomedical applications","volume":"172","author":"Liakos","year":"2018","journal-title":"Colloids Surf. B"},{"key":"ref165","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.2147\/IJN.S191340","article-title":"Antibacterial activity and mechanism of silver nanoparticles against multidrug-resistant Pseudomonas aeruginosa","volume":"14","author":"Liao","year":"2019","journal-title":"Int. J. Nanomedicine"},{"key":"ref166","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1177\/0960327110385960","article-title":"Aconitine intoxication mimicking acute myocardial infarction","volume":"30","author":"Lin","year":"2011","journal-title":"Hum. Exp. Toxicol."},{"key":"ref167","doi-asserted-by":"publisher","first-page":"618","DOI":"10.3390\/livers3040041","article-title":"Hidden dangers: herbal and dietary supplement induced hepatotoxicity","volume":"3","author":"Lin","year":"2023","journal-title":"Liver"},{"key":"ref168","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.3390\/molecules27041372","article-title":"A review of liposomes as a drug delivery system: current status of approved products, regulatory environments, and future perspectives","volume":"27","author":"Liu","year":"2022","journal-title":"Molecules"},{"key":"ref169","doi-asserted-by":"publisher","first-page":"29985","DOI":"10.1038\/srep29985","article-title":"Antibacterial effect of copper-bearing titanium alloy (Ti-Cu) against Streptococcus mutans and Porphyromonas gingivalis","volume":"6","author":"Liu","year":"2016","journal-title":"Sci. Rep."},{"key":"ref170","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1128\/AAC.05702-11","article-title":"Resistance to linezolid caused by modifications at its binding site on the ribosome","volume":"56","author":"Long","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref171","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02329","article-title":"Bactericidal property of oregano oil against multidrug-resistant clinical isolates","volume":"9","author":"Lu","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref172","doi-asserted-by":"publisher","first-page":"761084","DOI":"10.3389\/fmicb.2021.761084","article-title":"Biogenic synthesis of MnO2 nanoparticles with leaf extract of Viola betonicifolia for enhanced antioxidant, antimicrobial, cytotoxic, and biocompatible applications","volume":"12","author":"Lu","year":"2021","journal-title":"Front. Microbiol."},{"key":"ref173","doi-asserted-by":"publisher","first-page":"15557","DOI":"10.1021\/acsomega.0c01716","article-title":"Zein nanoparticles impregnated with eugenol and garlic essential oils for treating fish pathogens","volume":"5","author":"Luis","year":"2020","journal-title":"ACS Omega"},{"key":"ref174","doi-asserted-by":"publisher","first-page":"8855","DOI":"10.3390\/ijms24108855","article-title":"Trichosporon asahii PLA2 gene enhances drug resistance to azoles by improving drug efflux and biofilm formation","volume":"24","author":"Ma","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"ref175","doi-asserted-by":"publisher","first-page":"e0085122","DOI":"10.1128\/spectrum.00851-22","article-title":"Comparative in vitro study of biofilm formation and antimicrobial susceptibility in gram-negative Bacilli isolated from prosthetic joint infections","volume":"10","author":"Macias-Valcayo","year":"2022","journal-title":"Microbiol. Spectr."},{"key":"ref176","doi-asserted-by":"publisher","first-page":"2257","DOI":"10.1007\/s00203-021-02248-z","article-title":"Antibacterial properties of Allium sativum L. against the most emerging multidrug-resistant bacteria and its synergy with antibiotics","volume":"203","author":"Magry\u015b","year":"2021","journal-title":"Arch. Microbiol."},{"key":"ref177","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1038\/s41579-020-0420-1","article-title":"Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections","volume":"19","author":"Makabenta","year":"2020","journal-title":"Nat. Rev. Microbiol."},{"key":"ref178","doi-asserted-by":"publisher","first-page":"4069","DOI":"10.1002\/smll.201301081","article-title":"Eradication of multi-drug resistant bacteria by a novel Zn-doped CuO nanocomposite","volume":"9","author":"Malka","year":"2013","journal-title":"Small"},{"key":"ref179","doi-asserted-by":"publisher","first-page":"687660","DOI":"10.3389\/fchem.2021.687660","article-title":"Nanoantibiotics: functions and properties at the nanoscale to combat antibiotic resistance","volume":"9","author":"Mamun","year":"2021","journal-title":"Front. Chem."},{"key":"ref180","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.3390\/pathogens10101310","article-title":"Bacterial antibiotic resistance: the most critical pathogens","volume":"10","author":"Mancuso","year":"2021","journal-title":"Pathogens"},{"key":"ref181","doi-asserted-by":"publisher","first-page":"942916","DOI":"10.1155\/2013\/942916","article-title":"Mechanisms of nanoparticle-induced oxidative stress and toxicity","volume":"2013","author":"Manke","year":"2013","journal-title":"Biomed. Res. Int."},{"key":"ref182","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.ecoenv.2017.07.004","article-title":"Preparation of nanoscale iron (oxide, oxyhydroxides and zero-valent) particles derived from blueberries: reactivity, characterization and removal mechanism of arsenate","volume":"145","author":"Manqui\u00e1n-Cerda","year":"2017","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref183","doi-asserted-by":"publisher","first-page":"10655","DOI":"10.1007\/s00253-015-6938-x","article-title":"Antimicrobial potentials of Helicteres isora silver nanoparticles against extensively drug-resistant (XDR) clinical isolates of Pseudomonas aeruginosa","volume":"99","author":"Mapara","year":"2015","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref184","doi-asserted-by":"publisher","first-page":"106241","DOI":"10.1016\/j.ultsonch.2022.106241","article-title":"Ultrasonic-assisted synthesis of lignin-capped Cu2O nanocomposite with antibiofilm properties","volume":"92","author":"Maruthapandi","year":"2023","journal-title":"Ultrason. Sonochem."},{"key":"ref185","doi-asserted-by":"publisher","first-page":"260","DOI":"10.3390\/antibiotics8040260","article-title":"The use of nanomedicine for targeted therapy against bacterial infections","volume":"8","author":"Masri","year":"2019","journal-title":"Antibiotics"},{"key":"ref186","doi-asserted-by":"publisher","first-page":"820","DOI":"10.3389\/fmicb.2019.00820","article-title":"Biogenic synthesis of silver nanoparticles using phyllanthus emblicafruit extract and its inhibitory action against the pathogen acidovorax oryzaestrain RS-2 of rice bacterial brown stripe","volume":"10","author":"Masum","year":"2019","journal-title":"Front. Microbiol."},{"key":"ref187","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/s13065-022-00858-2","article-title":"In vitro total phenolics, total flavonoids, antioxidant and antibacterial activities of selected medicinal plants using different solvent systems","volume":"16","author":"Mehmood","year":"2022","journal-title":"BMC Chem."},{"key":"ref188","doi-asserted-by":"publisher","first-page":"e1000819","DOI":"10.1371\/journal.pcbi.1000819","article-title":"A cell-based model for quorum sensing in heterogeneous bacterial colonies","volume":"6","author":"Melke","year":"2010","journal-title":"PLoS Comput. Biol."},{"key":"ref189","doi-asserted-by":"publisher","first-page":"105530","DOI":"10.1016\/j.micpath.2022.105530","article-title":"Characterization of turpentine nanoemulsion and assessment of its antibiofilm potential against methicillin-resistant Staphylococcus aureus","volume":"166","author":"Merghni","year":"2022","journal-title":"Microb. Pathog."},{"key":"ref190","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3389\/fpubh.2014.00145","article-title":"The antimicrobial resistance crisis: causes, consequences, and management","volume":"2","author":"Michael","year":"2014","journal-title":"Front. Public Health"},{"key":"ref191","doi-asserted-by":"publisher","first-page":"328","DOI":"10.3390\/antibiotics12020328","article-title":"Horizontal gene transfer of antibiotic resistance genes in biofilms","volume":"12","author":"Michaelis","year":"2023","journal-title":"Antibiotics"},{"key":"ref192","doi-asserted-by":"publisher","first-page":"7787","DOI":"10.1039\/C5CS00041F","article-title":"Inorganic nanoparticles engineered to attack bacteria","volume":"44","author":"Miller","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"ref193","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.ejpb.2019.12.008","article-title":"Enhancement in site-specific delivery of carvacrol for potential treatment of infected wounds using infection responsive nanoparticles loaded into dissolving microneedles: a proof of concept study","volume":"147","author":"Mir","year":"2020","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"ref194","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1002\/iub.2266","article-title":"The biofilm-associated bacterial infections unrelated to indwelling devices","volume":"72","author":"Mirzaei","year":"2020","journal-title":"IUBMB Life"},{"key":"ref195","doi-asserted-by":"publisher","first-page":"708","DOI":"10.3390\/antibiotics11060708","article-title":"Nanostructured antibiotics and their emerging medicinal applications: an overview of nanoantibiotics","volume":"11","author":"Modi","year":"2022","journal-title":"Antibiotics"},{"key":"ref196","doi-asserted-by":"publisher","first-page":"60","DOI":"10.7754\/Clin.Lab.2022.220315","article-title":"Antibacterial and anti-biofilm activities of silver nano particles conjugated to chitosan against multi-drug resistant bacteria","volume":"69","author":"Mohammadinejat","year":"2023","journal-title":"Clin. Lab."},{"key":"ref197","doi-asserted-by":"publisher","first-page":"20136","DOI":"10.1038\/s41598-021-99230-y","article-title":"Impact of target site mutations and plasmid associated resistance genes acquisition on resistance of Acinetobacter baumannii to fluoroquinolones","volume":"11","author":"Mohammed","year":"2021","journal-title":"Sci. Rep."},{"key":"ref198","doi-asserted-by":"publisher","first-page":"1028086","DOI":"10.3389\/fmicb.2022.1028086","article-title":"Nanotechnology in combating biofilm: a smart and promising therapeutic strategy","volume":"13","author":"Mohanta","year":"2023","journal-title":"Front. Microbiol."},{"key":"ref199","doi-asserted-by":"publisher","first-page":"70","DOI":"10.22037\/ijpr.2019.15578.13190","article-title":"Green synthesis and characterization of bismuth oxide nanoparticle using Mentha Pulegium extract","volume":"19","author":"Motakef-Kazemi","year":"2020","journal-title":"Iran. J. Pharm. Res."},{"key":"ref200","doi-asserted-by":"publisher","first-page":"1473","DOI":"10.3390\/antibiotics10121473","article-title":"Nanotechnology as a novel approach in combating microbes providing an alternative to antibiotics","volume":"10","author":"Mubeen","year":"2021","journal-title":"Antibiotics"},{"key":"ref201","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.VMBF-0016-2015","article-title":"Mechanisms of antibiotic resistance","volume":"4","author":"Munita","year":"2016","journal-title":"Microbiol. Spectr."},{"key":"ref202","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1002\/cjce.25142","article-title":"Green synthesis of copper oxide nanoparticles: characterization and applications for environmental and biomedical fields","volume":"102","author":"Naaz","year":"2023","journal-title":"Can. J. Chem. Eng."},{"key":"ref203","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1007\/s13237-022-00405-3","article-title":"Plant-derived natural products for drug discovery: current approaches and prospects","volume":"65","author":"Nasim","year":"2022","journal-title":"Nucleus"},{"key":"ref204","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1007\/s12010-023-04571-1","article-title":"Nanoemulsion-based system as a novel and promising approach for enhancing the antimicrobial and Antitumoral activity of Thymus vulgaris (L.) oil in human hepatocellular carcinoma cells","volume":"196","author":"Nasra","year":"2023","journal-title":"Appl. Biochem. Biotechnol."},{"key":"ref205","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1007\/s11259-022-10032-7","article-title":"Comparison of the prevalence, antibiotic resistance patterns, and biofilm formation ability of methicillin-resistant Staphylococcus pseudintermedius in healthy dogs and dogs with skin infections","volume":"47","author":"Naziri","year":"2022","journal-title":"Vet. Res. Commun."},{"key":"ref206","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1021\/acs.jnatprod.5b01055","article-title":"Natural products as sources of new drugs from 1981 to 2014","volume":"79","author":"Newman","year":"2016","journal-title":"J. Nat. Prod."},{"key":"ref207","doi-asserted-by":"publisher","first-page":"2531","DOI":"10.1007\/s10311-022-01425-w","article-title":"Formation, antimicrobial activity, and biomedical performance of plant-based nanoparticles: a review","volume":"20","author":"Nguyen","year":"2022","journal-title":"Environ. Chem. Lett."},{"key":"ref208","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1111\/1750-3841.16461","article-title":"Anti-inflammatory properties of an aldehydes-enriched fraction of grapefruit essential oil","volume":"88","author":"Nikolic","year":"2023","journal-title":"J. Food Sci."},{"key":"ref209","doi-asserted-by":"publisher","first-page":"259","DOI":"10.3390\/microorganisms11020259","article-title":"The cell wall, cell membrane and virulence factors of Staphylococcus aureus and their role in antibiotic resistance","volume":"11","author":"Nikolic","year":"2023","journal-title":"Microorganisms"},{"key":"ref210","doi-asserted-by":"publisher","first-page":"737288","DOI":"10.3389\/fmicb.2021.737288","article-title":"Function and inhibitory mechanisms of multidrug efflux pumps","volume":"12","author":"Nishino","year":"2021","journal-title":"Front. Microbiol."},{"key":"ref211","doi-asserted-by":"publisher","first-page":"516","DOI":"10.3390\/gels9070516","article-title":"Development and evaluation of nanoformulations containing timur oil and rosemary oil for treatment of topical fungal infections","volume":"9","author":"Noor","year":"2023","journal-title":"Gels"},{"key":"ref212","doi-asserted-by":"publisher","first-page":"14030","DOI":"10.1038\/s41598-023-41119-z","article-title":"Green synthesis of copper oxide nanoparticles and its efficiency in degradation of rifampicin antibiotic","volume":"13","author":"Nzilu","year":"2023","journal-title":"Sci. Rep."},{"key":"ref213","doi-asserted-by":"publisher","first-page":"2811","DOI":"10.1128\/AAC.46.9.2811-2820.2002","article-title":"Identification and analysis of amino acid mutations in porin IB that mediate intermediate-level resistance to penicillin and tetracycline in Neisseria gonorrhoeae","volume":"46","author":"Olesky","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref214","doi-asserted-by":"publisher","first-page":"911","DOI":"10.3389\/fmicb.2019.00911","article-title":"Antimicrobial activity of polyphenols and alkaloids in middle eastern plants","volume":"10","author":"Othman","year":"2019","journal-title":"Front. Microbiol."},{"key":"ref215","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/j.jfda.2016.04.001","article-title":"Antioxidant and antimicrobial phenolic compounds from extracts of cultivated and wild-grown Tunisian Ruta chalepensis","volume":"25","author":"Ouerghemmi","year":"2016","journal-title":"J. Food Drug Anal."},{"key":"ref216","doi-asserted-by":"publisher","first-page":"115","DOI":"10.5599\/admet.1172","article-title":"Recent advances in nanoparticles as antibacterial agent","volume":"10","author":"Ozdal","year":"2022","journal-title":"ADMET DMPK"},{"key":"ref217","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1007\/s11101-023-09909-5","article-title":"Encapsulated phenolic compounds: clinical efficacy of a novel delivery method","volume":"23","author":"Ozkan","year":"2024","journal-title":"Phytochem. Rev."},{"key":"ref218","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.biotechadv.2018.11.013","article-title":"Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies","volume":"37","author":"Pang","year":"2018","journal-title":"Biotechnol. Adv."},{"key":"ref219","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.3390\/antiox9121309","article-title":"Antioxidant, antimicrobial and antiviral properties of herbal materials","volume":"9","author":"Parham","year":"2020","journal-title":"Antioxidants"},{"key":"ref220","doi-asserted-by":"publisher","first-page":"12297","DOI":"10.1039\/D2NR01958B","article-title":"Mesoporous silica as a matrix for photocatalytic titanium dioxide nanoparticles: lipid membrane interactions","volume":"14","author":"Parra-Ortiz","year":"2022","journal-title":"Nanoscale"},{"key":"ref221","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s12951-018-0392-8","article-title":"Nano based drug delivery systems: recent developments and future prospects","volume":"16","author":"Patra","year":"2018","journal-title":"J. Nanobiotechnology"},{"key":"ref222","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1111\/lam.13144","article-title":"Bacterial biofilm formation on indwelling urethral catheters","volume":"68","author":"Pelling","year":"2019","journal-title":"Lett. Appl. Microbiol."},{"key":"ref223","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.phymed.2018.12.025","article-title":"The anti MRSA biofilm activity of Thymus vulgaris essential oil in nanovesicles","volume":"57","author":"Perez","year":"2019","journal-title":"Phytomedicine"},{"key":"ref224","doi-asserted-by":"publisher","first-page":"55","DOI":"10.4315\/0362-028X.JFP-08-403","article-title":"Inactivation of listeria monocytogenes and Escherichia coli O157:H7 biofilms by micelle-encapsulated eugenol and carvacrol","volume":"74","author":"P\u00e9rez-Conesa","year":"2011","journal-title":"J. Food Prot."},{"key":"ref225","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3390\/biom11020197","article-title":"Microwave-assisted rapid green synthesis of gold nanoparticles using seed extract of Trachyspermum ammi: ROS mediated biofilm inhibition and anticancer activity","volume":"11","author":"Perveen","year":"2021","journal-title":"Biomolecules"},{"key":"ref226","doi-asserted-by":"publisher","first-page":"2928","DOI":"10.3389\/fmicb.2018.02928","article-title":"Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens","volume":"9","author":"Peterson","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref227","doi-asserted-by":"publisher","first-page":"281","DOI":"10.3389\/fphar.2018.00281","article-title":"Antimicrobial peptides and their therapeutic potential for bacterial skin infections and wounds","volume":"9","author":"Pfalzgraff","year":"2018","journal-title":"Front. Pharmacol."},{"key":"ref228","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1021\/acs.biomac.5b01727","article-title":"Vancomycin functionalized nanoparticles for bactericidal biomaterial surfaces","volume":"17","author":"Pichavant","year":"2016","journal-title":"Biomacromolecules"},{"key":"ref229","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3233\/JRS-2012-0568","article-title":"Adverse effects of aromatherapy: a systematic review of case reports and case series","volume":"24","author":"Posadzki","year":"2012","journal-title":"Int. J. Risk Saf. Med."},{"key":"ref230","doi-asserted-by":"publisher","first-page":"761","DOI":"10.3390\/ijms231810761","article-title":"Polymicrobial biofilm organization of Staphylococcus aureus and Pseudomonas aeruginosa in a chronic wound environment","volume":"23","author":"Pouget","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"ref231","doi-asserted-by":"publisher","first-page":"100100","DOI":"10.1016\/j.mne.2021.100100","article-title":"Photocatalytic TiO2 nanomaterials as potential antimicrobial and antiviral agents: scope against blocking the SARS-COV-2 spread","volume":"14","author":"Prakash","year":"2022","journal-title":"Micro Nano Eng."},{"key":"ref232","doi-asserted-by":"publisher","first-page":"e10","DOI":"10.15190\/d.2019.13","article-title":"Communication is the key: biofilms, quorum sensing, formation and prevention","volume":"7","author":"Preda","year":"2019","journal-title":"Discoveries"},{"key":"ref233","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1179\/2047773215Y.0000000030","article-title":"Antimicrobial resistance: a global multifaceted phenomenon","volume":"109","author":"Prestinaci","year":"2015","journal-title":"Pathog. Glob. Health"},{"key":"ref234","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/s41392-022-01056-1","article-title":"Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics","volume":"7","author":"Qin","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"ref235","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.micpath.2017.09.062","article-title":"Antimicrobial and antibiofilm activities of nanoemulsions containing Eucalyptus globulus oil against Pseudomonas aeruginosa and Candida spp.","volume":"112","author":"Quatrin","year":"2017","journal-title":"Microb. Pathog."},{"key":"ref236","doi-asserted-by":"publisher","first-page":"220858","DOI":"10.1098\/rsos.220858","article-title":"Green synthesis of zinc oxide nanoparticles using Cocos nucifera leaf extract: characterization, antimicrobial, antioxidant and photocatalytic activity","volume":"9","author":"Rahman","year":"2022","journal-title":"R. Soc. Open Sci."},{"key":"ref237","doi-asserted-by":"publisher","first-page":"23","DOI":"10.4103\/ijo.IJO_947_19","article-title":"Study of biofilm formation in bacterial isolates from contact lens wearers","volume":"68","author":"Raksha","year":"2020","journal-title":"Indian J. Ophthalmol."},{"key":"ref238","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1080\/2314808X.2021.1905464","article-title":"Bacterial biofilm dependent catheter associated urinary tract infections: characterization, antibiotic resistance pattern and risk factors","volume":"8","author":"Ramadan","year":"2021","journal-title":"Egypt. J. Basic Appl. Sci."},{"key":"ref239","doi-asserted-by":"publisher","first-page":"2858","DOI":"10.3390\/microorganisms11122858","article-title":"Biofilm formation by Escherichia coli isolated from urinary tract infections from Aguascalientes, Mexico","volume":"11","author":"Ram\u00edrez Castillo","year":"2023","journal-title":"Microorganisms"},{"key":"ref240","doi-asserted-by":"publisher","first-page":"174","DOI":"10.2174\/1872211313666190911124626","article-title":"Nanoantibiotic formulations to combat antibiotic resistance-old wine in a new bottle","volume":"13","author":"Rana","year":"2019","journal-title":"Recent Pat. Drug Deliv. Formul."},{"key":"ref241","doi-asserted-by":"publisher","first-page":"5133","DOI":"10.1039\/D0FO00755B","article-title":"Physicochemical and antibacterial properties of fabricated ovalbumin-carvacrol gel nanoparticles","volume":"11","author":"Rao","year":"2020","journal-title":"Food Funct."},{"key":"ref242","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1080\/10826068.2021.1881907","article-title":"Encapsulation of Satureja khuzistanica jamzad essential oil in chitosan nanoparticles with enhanced antibacterial and anticancer activities","volume":"51","author":"Rashidipour","year":"2021","journal-title":"Prep. Biochem. Biotechnol."},{"key":"ref243","doi-asserted-by":"publisher","first-page":"377","DOI":"10.2217\/fmb-2019-0327","article-title":"Nanotechnology in biofilm prevention","volume":"15","author":"Robino","year":"2020","journal-title":"Future Microbiol."},{"key":"ref244","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1111\/j.1469-0691.2012.04002.x","article-title":"Influence of material on the development of device-associated infections","volume":"18","author":"Rochford","year":"2012","journal-title":"Clin. Microbiol. Infect."},{"key":"ref245","doi-asserted-by":"publisher","first-page":"118575","DOI":"10.1016\/j.ijpharm.2019.118575","article-title":"Hybrid ofloxacin\/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties","volume":"569","author":"Rodenak-Kladniew","year":"2019","journal-title":"Int. J. Pharm."},{"key":"ref246","doi-asserted-by":"publisher","first-page":"3095","DOI":"10.1038\/s41467-018-05551-4","article-title":"Molecular insights into antibiotic resistance\u2014how a binding protein traps albicidin","volume":"9","author":"Rostock","year":"2018","journal-title":"Nat. Commun."},{"key":"ref247","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1097\/SLA.0000000000003053","article-title":"Staphylococcus aureus biofilm infection compromises wound healing by causing deficiencies in granulation tissue collagen","volume":"271","author":"Roy","year":"2020","journal-title":"Ann. Surg."},{"key":"ref248","doi-asserted-by":"publisher","first-page":"6842","DOI":"10.1021\/acs.biochem.5b01008","article-title":"Crystal structure of the zorbamycin-binding protein ZbmA, the primary self-resistance element in Streptomyces flavoviridis ATCC21892","volume":"54","author":"Rudolf","year":"2015","journal-title":"Biochemistry"},{"key":"ref249","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1111\/j.1574-695X.2006.00068.x","article-title":"Carbohydrate-containing components of biofilms produced in vitro by some staphylococcal strains related to orthopaedic prosthesis infections","volume":"47","author":"Sadovskaya","year":"2006","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"ref250","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1007\/s11671-007-9104-2","article-title":"In vitro structural and functional evaluation of gold nanoparticles conjugated antibiotics","volume":"2","author":"Saha","year":"2007","journal-title":"Nanoscale Res. Lett."},{"key":"ref251","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3390\/jox11040013","article-title":"Review on multiple facets of drug resistance: a rising challenge in the 21st century","volume":"11","author":"Saha","year":"2021","journal-title":"J. Xenobiot."},{"key":"ref252","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.3390\/healthcare11131946","article-title":"Antimicrobial resistance: a growing serious threat for global public health","volume":"11","author":"Salam","year":"2023","journal-title":"Healthcare"},{"key":"ref253","doi-asserted-by":"publisher","first-page":"554","DOI":"10.3390\/microorganisms11030554","article-title":"Evaluation of the toxic activity of the graphene oxide in the ex vivo model of human PBMC infection with Mycobacterium tuberculosis","volume":"11","author":"Salustri","year":"2023","journal-title":"Microorganisms"},{"key":"ref254","doi-asserted-by":"publisher","first-page":"979","DOI":"10.2217\/fmb.12.68","article-title":"Plant-derived antimicrobial compounds: alternatives to antibiotics","volume":"7","author":"Savoia","year":"2012","journal-title":"Future Microbiol."},{"key":"ref255","doi-asserted-by":"publisher","first-page":"2232","DOI":"10.1021\/acsbiomaterials.1c01516","article-title":"Nanotechnology approaches for rapid detection and theranostics of antimicrobial resistant bacterial infections","volume":"8","author":"Saxena","year":"2022","journal-title":"ACS Biomater Sci. Eng."},{"key":"ref256","doi-asserted-by":"publisher","first-page":"e00026","DOI":"10.1128\/MMBR.00026-19","article-title":"Staphylococcal biofilm development: structure, regulation, and treatment strategies","volume":"84","author":"Schilcher","year":"2020","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"ref257","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3390\/eca2022-12727","article-title":"Plant-based nanoantibiotics: an effective strategy to overcoming on antibiotic resistance","volume":"12","author":"Seyyedi-Mansour","year":"2022","journal-title":"Med. Sci. Forum"},{"key":"ref258","doi-asserted-by":"publisher","first-page":"2468","DOI":"10.3390\/ijms20102468","article-title":"Mechanistic insights into the antimicrobial actions of metallic nanoparticles and their implications for multidrug resistance","volume":"20","author":"Shaikh","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"ref259","doi-asserted-by":"publisher","first-page":"70","DOI":"10.3390\/molecules22010070","article-title":"Biological activities of essential oils: from plant chemoecology to traditional healing systems","volume":"22","author":"Sharifi-Rad","year":"2017","journal-title":"Molecules"},{"key":"ref260","doi-asserted-by":"publisher","first-page":"100084","DOI":"10.1016\/j.medmic.2023.100084","article-title":"Biofilms: understanding the structure and contribution towards bacterial resistance in antibiotics","volume":"16","author":"Shree","year":"2023","journal-title":"Med. Microecol."},{"key":"ref261","doi-asserted-by":"publisher","first-page":"3402","DOI":"10.1038\/s41467-023-38507-4","article-title":"Efflux pump gene amplifications bypass necessity of multiple target mutations for resistance against dual-targeting antibiotic","volume":"14","author":"Silva","year":"2023","journal-title":"Nat. Commun."},{"key":"ref262","doi-asserted-by":"publisher","first-page":"2056","DOI":"10.1021\/jf104402t","article-title":"Curcumin nanoparticles: preparation, characterization, and antimicrobial study","volume":"59","author":"Singh","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"ref263","doi-asserted-by":"publisher","first-page":"4727","DOI":"10.2147\/IJN.S419369","article-title":"Revisiting the green synthesis of nanoparticles: uncovering influences of plant extracts as reducing agents for enhanced synthesis efficiency and its biomedical applications","volume":"18","author":"Singh","year":"2023","journal-title":"Int. J. Nanomedicine"},{"key":"ref264","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.3390\/nano8121009","article-title":"Antimicrobial effects of biogenic nanoparticles","volume":"8","author":"Singh","year":"2018","journal-title":"Nanomaterials"},{"key":"ref265","doi-asserted-by":"publisher","first-page":"7513","DOI":"10.3390\/molecules27217513","article-title":"Phenolic compounds in active packaging and edible films\/coatings: natural bioactive molecules and novel packaging ingredients","volume":"27","author":"Singh","year":"2022","journal-title":"Molecules"},{"key":"ref266","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/s12951-014-0040-x","article-title":"Green silver nanoparticles of Phyllanthus amarus: as an antibacterial agent against multi drug resistant clinical isolates of Pseudomonas aeruginosa","volume":"12","author":"Singh","year":"2014","journal-title":"J. Nanobiotechnology"},{"key":"ref267","first-page":"197","article-title":"Chapter nine-herb-drug interactions of commonly used Chinese medicinal herbs","volume-title":"International review of neurobiology","author":"Singh","year":"2017"},{"key":"ref268","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1007\/s40820-015-0040-x","article-title":"Review on zinc oxide nanoparticles: antibacterial activity and toxicity mechanism","volume":"7","author":"Sirelkhatim","year":"2015","journal-title":"Nanomicro Lett."},{"key":"ref269","doi-asserted-by":"publisher","first-page":"360","DOI":"10.3389\/fchem.2018.00360","article-title":"Nanomedicine: principles, properties, and regulatory issues","volume":"6","author":"Soares","year":"2018","journal-title":"Front. Chem."},{"key":"ref270","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.jcis.2004.02.012","article-title":"Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for gram-negative bacteria","volume":"275","author":"Sondi","year":"2004","journal-title":"J. Colloid Interface Sci."},{"key":"ref271","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1093\/jac\/dkz378","article-title":"Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa","volume":"75","author":"Soren","year":"2020","journal-title":"J. Antimicrob. Chemother."},{"key":"ref272","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1574-6968.2006.00501.x","article-title":"Detection of quorum-sensing N-acyl homoserine lactone signal molecules by bacterial biosensors","volume":"266","author":"Steindler","year":"2007","journal-title":"FEMS Microbiol. Lett."},{"key":"ref273","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.chembiol.2015.12.011","article-title":"Cold stress makes Escherichia coli susceptible to glycopeptide antibiotics by altering outer membrane integrity","volume":"23","author":"Stokes","year":"2016","journal-title":"Cell Chem. Biol."},{"key":"ref274","doi-asserted-by":"publisher","first-page":"67","DOI":"10.2147\/IJN.S79982","article-title":"Eucalyptus oil nanoemulsion-impregnated chitosan film: antibacterial effects against a clinical pathogen, Staphylococcus aureus, in vitro","volume":"10","author":"Sugumar","year":"2015","journal-title":"Int. J. Nanomedicine"},{"key":"ref275","doi-asserted-by":"publisher","first-page":"100134","DOI":"10.1016\/j.medidd.2022.100134","article-title":"Nano-based drug delivery systems: conventional drug delivery routes, recent developments and future prospects","volume":"15","author":"Sultana","year":"2022","journal-title":"Med. Drug Discov."},{"key":"ref276","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/j.micpath.2018.10.017","article-title":"Formulation of nanoemulsion from leaves essential oil of Ocimum basilicum L. and its antibacterial, antioxidant and larvicidal activities (Culex quinquefasciatus)","volume":"125","author":"Sundararajan","year":"2018","journal-title":"Microb. Pathog."},{"key":"ref277","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.1021\/acs.accounts.1c00048","article-title":"The enzymes of the rifamycin antibiotic resistome","volume":"54","author":"Surette","year":"2021","journal-title":"Acc. Chem. Res."},{"key":"ref278","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.jot.2021.05.008","article-title":"Biofilm properties in relation to treatment outcome in patients with first-time periprosthetic hip or knee joint infection","volume":"30","author":"Svensson Malchau","year":"2021","journal-title":"J. Orthop. Translat."},{"key":"ref279","doi-asserted-by":"publisher","first-page":"5738","DOI":"10.3390\/ijms232415738","article-title":"Nanomaterials for delivering antibiotics in the therapy of pneumonia","volume":"23","author":"Tang","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"ref280","doi-asserted-by":"publisher","first-page":"e19486","DOI":"10.1016\/j.heliyon.2023.e19486","article-title":"The functional repertoire of AmpR in the AmpC \u03b2-lactamase high expression and decreasing \u03b2-lactam and aminoglycosides resistance in ESBL Citrobacter freundii","volume":"9","author":"Tariq","year":"2023","journal-title":"Heliyon"},{"key":"ref281","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.3390\/molecules23061366","article-title":"Bactericidal properties of plants-derived metal and metal oxide nanoparticles (NPs)","volume":"23","author":"Teow","year":"2018","journal-title":"Molecules"},{"key":"ref282","doi-asserted-by":"publisher","first-page":"27344","DOI":"10.1021\/acsomega.3c02709","article-title":"Biosynthesis and optimization of ZnO nanoparticles using Ocimum lamifolium leaf extract for electrochemical sensor and antibacterial activity","volume":"8","author":"Tilahun","year":"2023","journal-title":"ACS Omega"},{"key":"ref283","doi-asserted-by":"publisher","first-page":"100872","DOI":"10.1016\/j.coche.2022.100872","article-title":"Inorganic nanoparticle engineering against bacterial infections","volume":"38","author":"Tsikourkitoudi","year":"2022","journal-title":"Curr. Opin. Chem. Eng."},{"key":"ref284","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3390\/medicines5030093","article-title":"Flavonoids and other phenolic compounds from medicinal plants for pharmaceutical and medical aspects: an overview","volume":"5","author":"Tungmunnithum","year":"2018","journal-title":"Medicines"},{"key":"ref285","doi-asserted-by":"publisher","first-page":"1750","DOI":"10.1016\/j.jiph.2021.10.020","article-title":"Antibiotic resistance in microbes: history, mechanisms, therapeutic strategies and future prospects","volume":"14","author":"Uddin","year":"2021","journal-title":"J. Infect. Public Health"},{"key":"ref286","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.3390\/catal12111386","article-title":"Classification, synthetic, and characterization approaches to nanoparticles, and their applications in various fields of nanotechnology: a review","volume":"12","author":"Ullah","year":"2022","journal-title":"Catalysts"},{"key":"ref287","doi-asserted-by":"publisher","first-page":"7548","DOI":"10.1002\/anie.200604488","article-title":"Mesoporous materials for drug delivery","volume":"46","author":"Vallet-Reg\u00ed","year":"2007","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref288","doi-asserted-by":"publisher","first-page":"3553","DOI":"10.1007\/s00405-016-3958-9","article-title":"Haemophilus influenzae biofilm formation in chronic otitis media with effusion","volume":"273","author":"Van Hoecke","year":"2016","journal-title":"Eur. Arch. Otorrinolaringol."},{"key":"ref289","doi-asserted-by":"publisher","first-page":"1104615","DOI":"10.3389\/fcimb.2023.1104615","article-title":"The role of nanocomposites against biofilm infections in humans","volume":"13","author":"Varma","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"ref290","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2020\/6905631","article-title":"Nanoparticulate antibiotic systems as antibacterial agents and antibiotic delivery platforms to fight infections","volume":"2020","author":"Vassallo","year":"2020","journal-title":"J. Nanomater."},{"key":"ref291","doi-asserted-by":"publisher","first-page":"173","DOI":"10.3389\/fmicb.2016.00173","article-title":"Dissemination of antimicrobial resistance in microbial ecosystems through horizontal gene transfer","volume":"7","author":"von Wintersdorff","year":"2016","journal-title":"Front. Microbiol."},{"key":"ref292","doi-asserted-by":"publisher","first-page":"e07448","DOI":"10.1016\/j.heliyon.2021.e07448","article-title":"Mechanistic aspects of plant-based silver nanoparticles against multi-drug resistant bacteria","volume":"7","author":"Wahab","year":"2021","journal-title":"Heliyon"},{"key":"ref293","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1038\/35021219","article-title":"Molecular mechanisms that confer antibacterial drug resistance","volume":"406","author":"Walsh","year":"2000","journal-title":"Nature"},{"key":"ref294","doi-asserted-by":"publisher","first-page":"e0092823","DOI":"10.1128\/spectrum.00928-23","article-title":"PatA regulates isoniazid resistance by mediating mycolic acid synthesis and controls biofilm formation by affecting lipid synthesis in mycobacteria","volume":"11","author":"Wang","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"ref295","doi-asserted-by":"publisher","first-page":"e2661","DOI":"10.1111\/tbed.14615","article-title":"Dissemination of virulence and resistance genes among Klebsiella pneumoniae via outer membrane vesicle: an important plasmid transfer mechanism to promote the emergence of carbapenem-resistant hypervirulent Klebsiella pneumoniae","volume":"69","author":"Wang","year":"2022","journal-title":"Transbound. Emerg. Dis."},{"key":"ref296","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1007\/s11095-018-2464-8","article-title":"Co-delivery of ciprofloxacin and Colistin in liposomal formulations with enhanced in vitro antimicrobial activities against multidrug resistant Pseudomonas aeruginosa","volume":"35","author":"Wang","year":"2018","journal-title":"Pharm. Res."},{"key":"ref297","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1146\/annurev.cellbio.21.012704.131001","article-title":"Quorum sensing: cell-to-cell communication in bacteria","volume":"21","author":"Waters","year":"2005","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"ref298","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1002\/cpt1975175585","article-title":"Interaction of ephedrine and theophylline","volume":"17","author":"Weinberger","year":"1975","journal-title":"Clin. Pharmacol. Ther."},{"key":"ref299","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1128\/AAC.39.3.577","article-title":"Erythromycin resistance by ribosome modification","volume":"39","author":"Weisblum","year":"1995","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref300","doi-asserted-by":"publisher","first-page":"e0260821","DOI":"10.1128\/mBio.02608-21","article-title":"Efflux impacts intracellular accumulation only in actively growing bacterial cells","volume":"12","author":"Whittle","year":"2021","journal-title":"MBio"},{"key":"ref301","doi-asserted-by":"publisher","first-page":"e03584","DOI":"10.1128\/mBio.03584-20","article-title":"Biofilm development on urinary catheters promotes the appearance of viable but nonculturable bacteria","volume":"12","author":"Wilks","year":"2021","journal-title":"mBio"},{"key":"ref302","doi-asserted-by":"publisher","first-page":"251","DOI":"10.3390\/medicines2030251","article-title":"Modes of action of herbal medicines and plant secondary metabolites","volume":"2","author":"Wink","year":"2015","journal-title":"Medicines"},{"key":"ref303","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.12968\/bjon.2021.30.8.S4","article-title":"Biofilm and catheter-related bloodstream infections","volume":"30","author":"Wolcott","year":"2021","journal-title":"Br. J. Nurs."},{"key":"ref304","volume-title":"Global antimicrobial resistance and use surveillance system (GLASS) report 2022","year":"2022"},{"key":"ref305","doi-asserted-by":"publisher","first-page":"9587","DOI":"10.2147\/IJN.S279652","article-title":"Recent advances in oral nano-antibiotics for bacterial infection therapy","volume":"15","author":"Wu","year":"2020","journal-title":"Int. J. Nanomedicine"},{"key":"ref306","doi-asserted-by":"publisher","first-page":"2100767","DOI":"10.2807\/1560-7917.ES.2021.26.36.2100767","article-title":"Novel vancomycin resistance gene cluster in Enterococcus faecium ST1486, Belgium, June 2021","volume":"26","author":"Xavier","year":"2021","journal-title":"Eur. Secur."},{"key":"ref307","doi-asserted-by":"publisher","first-page":"2293841","DOI":"10.1080\/17518253.2023.2293841","article-title":"Green synthesis of ZnO, CuO and NiO nanoparticles using neem leaf extract and comparing their photocatalytic activity under solar irradiation","volume":"17","author":"Yadeta Gemachu","year":"2024","journal-title":"Green Chem. Lett. Rev."},{"key":"ref308","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.ijtb.2020.07.032","article-title":"Evaluation of magnesium oxide and zinc oxide nanoparticles against multi-drug-resistance Mycobacterium tuberculosis","volume":"68","author":"Yaghubi Kalurazi","year":"2020","journal-title":"Indian J. Tuberc."},{"key":"ref309","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.2215\/CJN.11571017","article-title":"Nephrotoxicity and Chinese herbal medicine","volume":"13","author":"Yang","year":"2018","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref310","doi-asserted-by":"publisher","first-page":"2315","DOI":"10.3390\/agronomy12102315","article-title":"Fabrication of copper oxide nanoparticles using Passiflora edulis extract for the estimation of antioxidant potential and photocatalytic methylene blue dye degradation","volume":"12","author":"Yasin","year":"2022","journal-title":"Agronomy"},{"key":"ref311","doi-asserted-by":"publisher","first-page":"286","DOI":"10.3389\/fchem.2020.00286","article-title":"Nano-based drug delivery or targeting to eradicate bacteria for infection mitigation: a review of recent advances","volume":"8","author":"Yeh","year":"2020","journal-title":"Front. Chem."},{"key":"ref312","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.3390\/antibiotics12101533","article-title":"The role of biofilms in contact lens associated fungal keratitis","volume":"12","author":"Yi","year":"2023","journal-title":"Antibiotics"},{"key":"ref313","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.3390\/ph14111198","article-title":"Effects of ephedrine-containing products on weight loss and lipid profiles: a systematic review and meta-analysis of randomized controlled trials","volume":"14","author":"Yoo","year":"2021","journal-title":"Pharmaceuticals"},{"key":"ref314","doi-asserted-by":"publisher","first-page":"10682","DOI":"10.1002\/slct.202101973","article-title":"Synergetic effect of rifampin loaded mussel-inspired silver nanoparticles for enhanced antibacterial activity against multidrug-resistant strain of Mycobacterium Tuberculosis","volume":"6","author":"Yu","year":"2021","journal-title":"ChemistrySelect"},{"key":"ref315","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s12989-019-0299-z","article-title":"Cellular toxicity and immunological effects of carbon-based nanomaterials","volume":"16","author":"Yuan","year":"2019","journal-title":"Part. Fibre Toxicol."},{"key":"ref316","doi-asserted-by":"publisher","first-page":"1596","DOI":"10.3390\/polym15071596","article-title":"Nanoparticles as drug delivery systems: a review of the implication of nanoparticles\u2019 physicochemical properties on responses in biological systems","volume":"15","author":"Yusuf","year":"2023","journal-title":"Polymers"},{"key":"ref317","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.foodchem.2016.10.037","article-title":"Enhancing the antimicrobial activity of d-limonene nanoemulsion with the inclusion of \u03b5-polylysine","volume":"221","author":"Zahi","year":"2016","journal-title":"Food Chem."},{"key":"ref318","doi-asserted-by":"publisher","first-page":"284","DOI":"10.3390\/molecules23020284","article-title":"Overcoming aminoglycoside enzymatic resistance: design of novel antibiotics and inhibitors","volume":"23","author":"Z\u00e1rate","year":"2018","journal-title":"Molecules"},{"key":"ref319","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1089\/wound.2012.0381","article-title":"Biofilms and inflammation in chronic wounds","volume":"2","author":"Zhao","year":"2013","journal-title":"Adv. Wound Care"},{"key":"ref320","doi-asserted-by":"publisher","first-page":"425","DOI":"10.3390\/microorganisms8030425","article-title":"Quorum-sensing regulation of antimicrobial resistance in Bacteria","volume":"8","author":"Zhao","year":"2020","journal-title":"Microorganisms"},{"key":"ref321","doi-asserted-by":"publisher","first-page":"589640","DOI":"10.3389\/fmicb.2020.589640","article-title":"Regulatory mechanisms and promising applications of quorum sensing-inhibiting agents in control of bacterial biofilm formation","volume":"11","author":"Zhou","year":"2020","journal-title":"Front. Microbiol."},{"key":"ref322","doi-asserted-by":"publisher","first-page":"801287","DOI":"10.3389\/fphar.2021.801287","article-title":"Safety evaluation of natural drugs in chronic skeletal disorders: a literature review of clinical trials in the past 20 years","volume":"12","author":"Zhou","year":"2022","journal-title":"Front. Pharmacol."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2024.1391345\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T06:11:47Z","timestamp":1736403107000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2024.1391345\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,9]]},"references-count":323,"alternative-id":["10.3389\/fmicb.2024.1391345"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2024.1391345","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,9]]},"article-number":"1391345"}}