{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T03:08:07Z","timestamp":1793502487979,"version":"4.5.0"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Kodamaea ohmeri<\/jats:italic>\n                      is a rare but significant emerging human pathogen, particularly in neonates, with high mortality rates. While most\n                      <jats:italic>K. ohmeri<\/jats:italic>\n                      infections are sporadic, they can be underestimated during hospital outbreaks owing to challenges with traditional identification methods. We conducted a retrospective study to determine the diagnostic accuracy of detecting\n                      <jats:italic>K. ohmeri<\/jats:italic>\n                      in candidemia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Six non-duplicated isolates (initially misidentified as\n                      <jats:italic>Candida dubliniensis<\/jats:italic>\n                      ) were collected from four patients in a single department over 1\u202fmonth. Clinical and whole-genome sequencing data of the outbreak strains were evaluated to identify possible outbreaks.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All patients presented atypical features at diagnosis, and isolates had a low minimum inhibitory concentration (MIC) for amphotericin B, 5-fluorocytosine, and echinocandins, except for fluconazole with a high MIC. Notably, Patient 4 had a high MIC for triazoles. The isolates were grouped into three clades based on core genome single-nucleotide polymorphisms and single-copy orthologous genes. Clade 1 contained isolates from Patients 1 and 2, suggesting a common infection source.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This study underscores the need for improved awareness of\n                      <jats:italic>K. ohmeri<\/jats:italic>\n                      infections, which, although rare, involve emerging fluconazole-resistant strains.\n                      <jats:italic>Kodamaea ohmeri<\/jats:italic>\n                      should be considered a potential nosocomial pathogen capable of causing outbreaks; overlooking these emerging human pathogens may have serious consequences.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmicb.2025.1572747","type":"journal-article","created":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T01:38:42Z","timestamp":1746063522000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Emerging pathogens: the underestimated risk of Kodamaea ohmeri infection in hospitals"],"prefix":"10.3389","volume":"16","author":[{"given":"Shuang-Jie","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-hui","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-yan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cun-Wei","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,5,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"766","DOI":"10.3109\/13693786.2011.572300","article-title":"Kodamaea ohmeri as an emerging pathogen: a case report and review of the literature","volume":"49","author":"Al-Sweih","year":"2011","journal-title":"Med. 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