{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T14:02:29Z","timestamp":1783000949300,"version":"3.54.5"},"reference-count":102,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p><jats:italic>Weissella paramesenteroides<\/jats:italic> UFTM 2.6.1, isolated from unpasteurized milk, is a potentially probiotic strain exhibiting desirable properties previously demonstrated in vitro, along with a confirmed safe and promising genetic profile based on whole-genome analysis. Due to the limited research on the ability of <jats:italic>Weissella<\/jats:italic> species to synthesize compounds with anti-quorum sensing activity, this study aimed to investigate the potential of <jats:italic>W. paramesenteroides<\/jats:italic> UFTM 2.6.1 to disrupt quorum sensing (QS) signaling and attenuate the virulence of <jats:italic>Listeria monocytogenes<\/jats:italic>, an important foodborne pathogen responsible for the zoonotic disease listeriosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The effects of <jats:italic>W. paramesenteroides<\/jats:italic> cell-free supernatant (<jats:italic>Wp<\/jats:italic>-CFS) were evaluated on the growth, biofilm formation, motility, and expression of QS- and virulence-related genes in <jats:italic>L. monocytogenes<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>Wp<\/jats:italic>-CFS exhibited bacteriostatic activity against L. monocytogenes strains isolated from food and food processing environments (<jats:italic>n<\/jats:italic>\u202f=\u202f21). Additionally, it consistently reduced biofilm formation and swarming motility, two well-known QS-regulated phenotypes in <jats:italic>L. monocytogenes<\/jats:italic>. Exposure to <jats:italic>Wp<\/jats:italic>-CFS (0.25x MIC; 7.81 mg\/mL), at 28\u00b0C for 24\u202fh, significantly downregulated the relative expression of the genes <jats:italic>luxS, agrA, flaA, motA, motB<\/jats:italic>, and <jats:italic>degU<\/jats:italic>, whereas the genes <jats:italic>sigB<\/jats:italic>, and <jats:italic>prfA<\/jats:italic> were upregulated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study represents the first report demonstrating the production of compounds by W. paramesenteroides aimed at disrupting the QS system of <jats:italic>L. monocytogenes<\/jats:italic>, offering novel insights into alternative approaches to attenuate pathogen virulence without relying on traditional antimicrobials.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmicb.2025.1601203","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T05:47:15Z","timestamp":1750225635000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Exploring the potential of Weissella paramesenteroides UFTM 2.6.1 in disrupting quorum sensing and attenuating virulence in Listeria monocytogenes"],"prefix":"10.3389","volume":"16","author":[{"given":"Isabela Sguilla","family":"Rotta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sthef\u00e2nia Dalva da Cunha","family":"Rezende","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo Felix","family":"Perini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos Vinicius","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe Alves","family":"de Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uelinton Manoel","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra Barbosa","family":"Ferreira Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline Dias","family":"Paiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"327","DOI":"10.3389\/fmicb.2018.00327","article-title":"Lipoteichoic acid inhibits Staphylococcus aureus biofilm formation","volume":"9","author":"Ahn","year":"2018","journal-title":"Front. Microbiol."},{"key":"ref2","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/B978-0-12-819470-6.00025-1","article-title":"Bacterial cell-to-cell communication and its relevance to food safety","volume-title":"Present knowledge in food safety: A risk-based approach through the food chain","author":"Almeida","year":"2023"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"2644","DOI":"10.1128\/AEM.72.4.2644-2650.2006","article-title":"Assessment of the roles of LuxS, S-ribosyl homocysteine, and autoinducer 2 in cell attachment during biofilm formation by Listeria monocytogenes EGD-e","volume":"72","author":"Belval","year":"2006","journal-title":"Appl. Environ. Microbiol."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"896898","DOI":"10.3389\/fcimb.2022.896898","article-title":"Flagellar motility during E. coli biofilm formation provides a competitive disadvantage which recedes in the presence of co-colonizers","volume":"12","author":"Benyoussef","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1016\/j.foodcont.2013.07.023","article-title":"Production of biofilm by Listeria monocytogenes in different materials and temperatures","volume":"35","author":"Bonsaglia","year":"2014","journal-title":"Food Control"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"445","DOI":"10.22159\/ajpcr.2017.v10i4.17039","article-title":"Quorum quenching potentials of probiotic Enterococcus durans Lab38 against methicillin resistant Staphylococcus aureus","volume":"10","author":"Boopathi","year":"2017","journal-title":"Asian J. Pharm. Clin. Res."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1128\/AAC.11.4.718","article-title":"Bacteriocin production by strains of Bacteroides isolated from human feces and the role of these strains in the bacterial ecology of the colon","volume":"11","author":"Booth","year":"1977","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"5","DOI":"10.2174\/1381612820666140905114627","article-title":"Quorum sensing inhibitors as anti-biofilm agents","volume":"21","author":"Brackman","year":"2015","journal-title":"Curr. Pharm. Des."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fmicb.2014.00068","article-title":"Transcriptome analysis of Listeria monocytogenes exposed to biocide stress reveals a multi-system response involving cell wall synthesis, sugar uptake, and motility","volume":"68","author":"Casey","year":"2014","journal-title":"Front Microbiol."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"8223","DOI":"10.1007\/s00253-017-8546-4","article-title":"Mechanistic understanding of phenyllactic acid mediated inhibition of quorum sensing and biofilm development in Pseudomonas aeruginosa","volume":"101","author":"Chatterjee","year":"2017","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"2989","DOI":"10.3390\/microorganisms11122989","article-title":"Association between the presence of resistance genes and sanitiser resistance of Listeria monocytogenes isolates recovered from different food-processing facilities","volume":"11","author":"Cheng","year":"2023","journal-title":"Microorganisms"},{"key":"ref14","volume-title":"Performance standards for antimicrobial susceptibility testing","year":"2023"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1111\/j.1365-2672.1993.tb01600.x","article-title":"Taxonomic studies on some Leuconostoc-like organisms from fermented sausages: description of a new genus Weissella for the Leuconostoc paramesenteroides group of species","volume":"75","author":"Collins","year":"1993","journal-title":"J. Appl. Bacteriol."},{"key":"ref16","doi-asserted-by":"publisher","first-page":"83","DOI":"10.3390\/microorganisms10010083","article-title":"Brucella and its hidden flagellar system","volume":"10","author":"Coloma-Rivero","year":"2022","journal-title":"Microorganisms"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1126\/science.284.5418.1318","article-title":"Bacterial biofilms: a common cause of persistent infections","volume":"284","author":"Costerton","year":"1999","journal-title":"Science"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"108696","DOI":"10.1016\/j.lwt.2019.108696","article-title":"Lactobacillus crustorum ZHG 2-1 as novel quorum-quenching bacteria reducing virulence factors and biofilms formation of Pseudomonas aeruginosa","volume":"117","author":"Cui","year":"2020","journal-title":"LWT"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"711","DOI":"10.3390\/fermentation8120711","article-title":"Quorum-sensing inhibitors from probiotics as a strategy to combat bacterial cell-to-cell communication involved in food spoilage and food safety","volume":"8","author":"Davares","year":"2022","journal-title":"Fermentation"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"4877","DOI":"10.1128\/AAC.01381-13","article-title":"Effect of nitroxides on swarming motility and biofilm formation, multicellular behaviors in Pseudomonas aeruginosa","volume":"57","author":"de la Fuente-N\u00fa\u00f1ez","year":"","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref22","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/j.mib.2013.06.013","article-title":"Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies","volume":"16","author":"de la Fuente-Nunez","year":"","journal-title":"Curr Opin Microbiol."},{"key":"ref23","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.mib.2011.01.005","article-title":"Regulation of Listeria virulence: PrfA master and commander","volume":"14","author":"de las Heras","year":"2011","journal-title":"Curr. Opin. Microbiol."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/j.lwt.2017.11.016","article-title":"Isolation of folate-producing Weissella spp. from Thai fermented fish (Plaa Som fug)","volume":"89","author":"Deatraksa","year":"2018","journal-title":"LWT"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.tim.2013.09.006","article-title":"Quorum sensing inhibitors: how strong is the evidence?","volume":"21","author":"Defoirdt","year":"2013","journal-title":"Trends Microbiol."},{"key":"ref26","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1128\/CMR.15.2.167-193.2002","article-title":"Biofilms: survival mechanisms of clinically relevant microorganisms","volume":"15","author":"Donlan","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"key":"ref27","doi-asserted-by":"publisher","first-page":"109405","DOI":"10.1016\/j.foodres.2020.109405","article-title":"Influence of different factors on biofilm formation of Listeria monocytogenes and the regulation of cheY gene","volume":"137","author":"Fan","year":"2020","journal-title":"Food Res. Int."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/j.foodcont.2018.02.047","article-title":"Effect of coenzyme Q0 on biofilm formation and attachment-invasion efficiency of Listeria monocytogenes","volume":"90","author":"Fan","year":"2018","journal-title":"Food Control"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"2896","DOI":"10.1002\/fsn3.2885","article-title":"Antimicrobial activity and safety features assessment of Weissella spp. from environmental sources","volume":"10","author":"Fhoula","year":"2022","journal-title":"Food Sci. Nutr."},{"key":"ref30","doi-asserted-by":"publisher","first-page":"405708","DOI":"10.1155\/2013\/405708","article-title":"Diversity and antimicrobial properties of lactic acid bacteria isolated from rhizosphere of olive trees and desert truffles of Tunisia","volume":"10","author":"Fhoula","year":"2013","journal-title":"Microorganisms."},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1289937","DOI":"10.3389\/fmicb.2023.1289937","article-title":"The Weissella and Periweissella genera: up-to-date taxonomy, ecology, safety, biotechnological, and probiotic potential","volume":"14","author":"Fusco","year":"2023","journal-title":"Front. Microbiol."},{"key":"ref1900","doi-asserted-by":"publisher","first-page":"1128","DOI":"10.1128\/mmbr.00034-19","article-title":"Cross Talk between SigB and PrfA in Listeria monocytogenes Facilitates Transitions between Extra- and Intracellular Environments","volume":"83","author":"Gaballa","year":"2019","journal-title":"Microbiol Mol Biol Rev."},{"key":"ref32","doi-asserted-by":"publisher","first-page":"898","DOI":"10.3389\/fmicb.2018.00898","article-title":"Biofilms in the Food Industry: Health Aspects and Control Methods","volume":"9","author":"Gali\u00e9","year":"2018","journal-title":"Front Microbiol."},{"key":"ref33","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.ijfoodmicro.2007.06.001","article-title":"Bacteriocin-based strategies for food biopreservation","volume":"120","author":"G\u00e1lvez","year":"2007","journal-title":"Int J Food Microbiol."},{"key":"ref34","doi-asserted-by":"publisher","first-page":"114232","DOI":"10.1016\/j.foodres.2024.114232","article-title":"Growth, biofilm formation, and motility of Listeria monocytogenes strains isolated from food and clinical samples located in Shanghai (China)","volume":"184","author":"Gao","year":"2024","journal-title":"Food Res. Int."},{"key":"ref35","doi-asserted-by":"publisher","first-page":"639","DOI":"10.4315\/JFP-21-135","article-title":"Controlling Listeria monocytogenes growth and biofilm formation using flavonoids","volume":"85","author":"Gemmell","year":"2022","journal-title":"J. Food Prot."},{"key":"ref36","doi-asserted-by":"publisher","first-page":"12318","DOI":"10.1073\/pnas.0404924101","article-title":"Listeria monocytogenes regulates flagellar motility gene expression through MogR, a transcriptional repressor required for virulence","volume":"101","author":"Gr\u00fcndling","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref6000","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1128\/AEM.03173-14","article-title":"Briandet R Exploring the Diversity of Listeria monocytogenes Biofilm Architecture by High-Throughput Confocal Laser Scanning Microscopy and the Predominance of the Honeycomb-Like Morphotype","volume":"81","author":"Guilbaud","year":"2015","journal-title":"Appl Environ Microbiol."},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1242","DOI":"10.3390\/biology2041242","article-title":"The role of the bacterial flagellum in adhesion and virulence","volume":"2","author":"Haiko","year":"2013","journal-title":"Biology"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.biortech.2018.03.007","article-title":"Mitigation of membrane biofouling by a quorum quenching bacterium for membrane bioreactors","volume":"258","author":"Ham","year":"2018","journal-title":"Bioresour. Technol."},{"key":"ref40","doi-asserted-by":"publisher","first-page":"978831","DOI":"10.3389\/fnut.2022.978831","article-title":"Weissella cibaria riboflavin-overproducing and dextran-producing strains useful for the development of functional bread","volume":"9","author":"Hern\u00e1ndez-Alc\u00e1ntara","year":"2022","journal-title":"Front. Nutr."},{"key":"ref41","doi-asserted-by":"publisher","first-page":"110595","DOI":"10.1016\/j.foodres.2021.110595","article-title":"Listeria monocytogenes biofilm inhibition on food contact surfaces by application of postbiotics from Lactobacillus curvatus B.67 and Lactobacillus plantarum M.2","volume":"148","author":"Hossain","year":"2021","journal-title":"Food Res. Int."},{"key":"ref42","doi-asserted-by":"publisher","first-page":"7981","DOI":"10.1128\/aem.01281-07","article-title":"Transcriptomic and phenotypic analyses suggest a network between the transcriptional regulators HrcA and \u03c3B in Listeria monocytogenes","volume":"73","author":"Hu","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"ref43","doi-asserted-by":"publisher","first-page":"106886","DOI":"10.1016\/j.foodcont.2019.106886","article-title":"Enhanced antibacterial and antibiofilm functions of the curcumin-mediated photodynamic inactivation against Listeria monocytogenes","volume":"108","author":"Huang","year":"2020","journal-title":"Food Control"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"192","DOI":"10.5217\/ir.2018.00106","article-title":"Evaluation of commercial probiotic lactic cultures against biofilm formation by Cronobacter sakazakii","volume":"17","author":"Jamwal","year":"2019","journal-title":"Intest Res."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"108804","DOI":"10.1016\/j.ijfoodmicro.2020.108804","article-title":"Role of Lactobacillus biofilms in Listeria monocytogenes adhesion to glass surfaces","volume":"334","author":"Jara","year":"2020","journal-title":"Int. J. Food Microbiol."},{"key":"ref47","doi-asserted-by":"publisher","first-page":"110394","DOI":"10.1016\/j.foodres.2021.110394","article-title":"Role of the VirSR-VirAB system in biofilm formation of Listeria monocytogenes EGD-e","volume":"145","author":"Jiang","year":"2021","journal-title":"Food Res. Int."},{"key":"ref48","doi-asserted-by":"publisher","first-page":"2964","DOI":"10.1016\/j.ijbiomac.2020.08.185","article-title":"Overview of exopolysaccharides produced by Weissella genus \u2013 a review","volume":"164","author":"Kavitake","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"ref49","doi-asserted-by":"publisher","first-page":"e15042","DOI":"10.1111\/jfpp.15042","article-title":"Control of Listeria monocytogenes biofilm on industrial surfaces by cell-free extracts of Lactobacillus plantarum","volume":"45","author":"K\u0131ran","year":"2021","journal-title":"J. Food Process. Preserv."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.lwt.2017.05.042","article-title":"Biofilm formation and microscopic analysis of biofilms formed by Listeria monocytogenes in a food processing context","volume":"84","author":"Kocot","year":"2017","journal-title":"LWT-Food Sci. Techonol."},{"key":"ref51","doi-asserted-by":"publisher","first-page":"4112","DOI":"10.3390\/foods13244112","article-title":"Riboflavin and dextran-producing Weissella confusa FS54 B2: characterization and testing for development of fermented plant-based beverages","volume":"13","author":"Lahmar","year":"2024","journal-title":"Food Secur."},{"key":"ref52","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s10068-020-00837-0","article-title":"Antimicrobial and anti-biofilm effects of probiotic Lactobacillus plantarum KU200656 isolated from kimchi","volume":"30","author":"Lee","year":"2021","journal-title":"Food Sci. Biotechnol."},{"key":"ref7000","doi-asserted-by":"publisher","first-page":"106950","DOI":"10.1016\/j.fbio.2025.106950","article-title":"The anti-biofilm and anti-virulence mechanisms of carvacrol against Listeria monocytogenes and the application in food systems","volume":"69","author":"Li","year":"2025","journal-title":"Food Bioscience"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"3062","DOI":"10.1080\/21505594.2021.2010398","article-title":"Paeoniflorin reduces luxS\/AI-2 system-controlled biofilm formation and virulence in Streptococcus suis","volume":"12","author":"Li","year":"2021","journal-title":"Virulence"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1046\/j.1365-2958.1998.00830.x","article-title":"Transmembrane topology and histidine protein kinase activity of AgrC, the agr signal receptor in Staphylococcus aureus","volume":"28","author":"Lina","year":"1998","journal-title":"Mol. Microbiol."},{"key":"ref55","doi-asserted-by":"publisher","first-page":"e4592","DOI":"10.1002\/fsn3.4592","article-title":"Evaluation of safety and probiotic properties of Weissella spp. in fermented vegetables from Xi\u2019an, Shaanxi, China","volume":"13","author":"Liu","year":"2024","journal-title":"Food Sci. Nutr."},{"key":"ref56","doi-asserted-by":"publisher","first-page":"75","DOI":"10.3390\/fermentation8020075","article-title":"Inhibition activity of Plantaricin Q7 produced by Lactobacillus plantarum Q7 against Listeria monocytogenes and its biofilm","volume":"8","author":"Liu","year":"2022","journal-title":"Fermentation"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"617473","DOI":"10.3389\/fmicb.2020.617473","article-title":"Inhibition of biofilm formation and related gene expression of Listeria monocytogenes in response to four natural antimicrobial compounds and sodium hypochlorite","volume":"11","author":"Liu","year":"2021","journal-title":"Front. Microbiol."},{"key":"ref58","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"110439","DOI":"10.1016\/j.lwt.2020.110439","article-title":"Lactobacillus plantarum CY 1-1: a novel quorum quenching bacteria and anti-biofilm agent against Aeromonas sobria","volume":"137","author":"Lv","year":"2021","journal-title":"LWT"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"5853","DOI":"10.1038\/s41598-020-62610-x","article-title":"Taxogenomic assessment and genomic characterisation of Weissella cibaria strain 92 able to metabolise oligosaccharides derived from dietary fibres","volume":"10","author":"M\u00e5nberger","year":"2020","journal-title":"Sci. Rep."},{"key":"ref61","doi-asserted-by":"publisher","first-page":"2897","DOI":"10.1007\/s11030-023-10722-7","article-title":"Lactic acid bacteria secreted proteins as potential Listeria monocytogenes quorum sensing inhibitors","volume":"28","author":"Marques","year":"2024","journal-title":"Mol. Divers."},{"key":"ref62","doi-asserted-by":"publisher","first-page":"2872","DOI":"10.3390\/foods11182872","article-title":"Anti-biofilm activity of cell-free supernatants of selected lactic acid bacteria against Listeria monocytogenes isolated from avocado and cucumber fruits, and from an avocado processing plant","volume":"11","author":"Masebe","year":"2022","journal-title":"Food Secur."},{"key":"ref63","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.mib.2013.06.003","article-title":"Faecalibacterium prausnitzii and human intestinal health","volume":"16","author":"Miquel","year":"2016","journal-title":"Curr. Opin. Microbiol."},{"key":"ref64","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.lwt.2019.05.072","article-title":"Characterization and application of postbiotics of Lactobacillus spp. on Listeria monocytogenes in vitro and in food models","volume":"111","author":"Moradi","year":"2019","journal-title":"LWT"},{"key":"ref5000","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.diagmicrobio.2007.05.013","article-title":"In vitro antibacterial activities of tigecycline and comparative agents by time-kill kinetic studies in fresh Mueller-Hinton broth","volume":"59","author":"Petersen","year":"2007","journal-title":"Diagn. Microbiol."},{"key":"ref66","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s13213-017-1277-z","article-title":"Comparative transcriptomic analysis of Listeria monocytogenes reveals upregulation of stress genes and downregulation of virulence genes in response to essential oil extracted from Baccharis psiadioides","volume":"67","author":"Pieta","year":"2017","journal-title":"Ann. Microbiol."},{"key":"ref67","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1111\/ijfs.12316","article-title":"Efficacy of bovicin HC5 and nisin combination against Listeria monocytogenes and Staphylococcus aureus in fresh cheese","volume":"49","author":"Pimentel-Filho","year":"2014","journal-title":"Int J Food Sci Technol."},{"key":"ref68","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.ijfoodmicro.2016.08.029","article-title":"Variability in biofilm formation by Listeria monocytogenes strains on stainless steel and polystyrene surfaces and resistance to sanitizers","volume":"223","author":"Poimenidou","year":"2016","journal-title":"Int. J. Food Microbiol."},{"key":"ref69","doi-asserted-by":"publisher","first-page":"363","DOI":"10.3390\/microorganisms11020363","article-title":"Inhibition of Listeria monocytogenes growth, adherence and invasion in Caco-2 cells by potential probiotic lactic acid bacteria isolated from fecal samples of healthy neonates","volume":"11","author":"Poimenidou","year":"2009","journal-title":"Microorganisms"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"1474","DOI":"10.3168\/jds.2020-18959","article-title":"Purification, characterization, and mode of action of a novel bacteriocin BM173 from Lactobacillus crustorum MN047 and its effect on biofilm formation of Escherichia coli and Staphylococcus aureus","volume":"104","author":"Qiao","year":"2021","journal-title":"J. Dairy Sci."},{"key":"ref71","doi-asserted-by":"publisher","first-page":"316","DOI":"10.3390\/dairy4020022","article-title":"Listeria monocytogenes: an inconvenient hurdle for the dairy industry","volume":"4","author":"Ribeiro","year":"2023","journal-title":"Dairy"},{"key":"ref72","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1111\/j.1365-2958.2008.06589.x","article-title":"AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes","volume":"71","author":"Riedel","year":"2009","journal-title":"Mol. Microbiol."},{"key":"ref73","doi-asserted-by":"publisher","first-page":"6125","DOI":"10.1128\/AEM.00608-07","article-title":"Agr system of Listeria monocytogenes EGD-e: role in adherence and differential expression pattern","volume":"73","author":"Rieu","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"ref74","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1007\/s11274-019-2675-0","article-title":"Inhibitory effect of bacteriocins from enterococci on developing and preformed biofilms of Listeria monocytogenes, Listeria ivanovii and Listeria innocua","volume":"35","author":"Rocha","year":"2019","journal-title":"World J. Microbiol. Biotechnol."},{"key":"ref75","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12602-024-10409-x","article-title":"Unlocking probiotic potential: genomic insights into Weissella paramesenteroides UFTM 2.6.1","volume":"1","author":"Rocha","year":"2024","journal-title":"Probiot. Antimicrob. 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C\u00e2ndido Tostes"},{"key":"ref78","doi-asserted-by":"publisher","first-page":"735931","DOI":"10.3389\/fmicb.2021.735931","article-title":"Exploring phenolic compounds as quorum sensing inhibitors in Listeria monocytogenes","volume":"12","author":"Santos","year":"2021","journal-title":"Front. Microbiol."},{"key":"ref79","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1042\/BJ20141251","volume":"468","author":"Segev-Zarko","year":"2015","journal-title":"Mechanisms of biofilm inhibition and degradation by antimicrobial peptides Available to Purchase Biochem J."},{"key":"ref80","doi-asserted-by":"publisher","first-page":"5653","DOI":"10.1128\/AEM.00048-06","article-title":"A mutation in the luxS gene influences Listeria monocytogenes biofilm formation","volume":"72","author":"Sela","year":"2006","journal-title":"Appl. Environ. Microbiol."},{"key":"ref81","doi-asserted-by":"publisher","first-page":"2993","DOI":"10.1080\/87559129.2024.2317283","article-title":"Potential application of Lactiplantibacillus plantarum in food bio-preservation \u2013 a comprehensive review with a focus on the antibacterial and anti-virulence effects on foodborne pathogens","volume":"40","author":"Shi","year":"2024","journal-title":"Food Rev. Int."},{"key":"ref82","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.3390\/microorganisms12071354","article-title":"Biofilm formation, motility, and virulence of Listeria monocytogenes are reduced by deletion of the gene lmo0159, a novel Listerial LPXTG surface protein","volume":"12","author":"Shi","year":"2023","journal-title":"Microorganisms"},{"key":"ref84","doi-asserted-by":"publisher","first-page":"1406904","DOI":"10.3389\/fmicb.2024.1406904","article-title":"Biosynthesis, classification, properties, and applications of Weissella bacteriocins","volume":"15","author":"Singh","year":"2024","journal-title":"Front. Microbiol."},{"key":"ref85","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1007\/s12223-019-00721-3","article-title":"Impairment of Cronobacter sakazakii and Listeria monocytogenes biofilms by cell-free preparations of lactobacilli of goat milk origin","volume":"65","author":"Singh","year":"2020","journal-title":"Folia Microbiol."},{"key":"ref86","doi-asserted-by":"publisher","first-page":"5473","DOI":"10.1128\/AEM.00468-12","article-title":"Quorum sensing in the context of food microbiology","volume":"78","author":"Skandamis","year":"2012","journal-title":"Appl. Environ. Microbiol."},{"key":"ref87","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/S0167-7012(00)00122-6","article-title":"A modified microtiter-plate test for quantification of staphylococcal biofilm formation","volume":"40","author":"Stepan\u00f3vic","year":"2000","journal-title":"J. Microbiol. 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Microbiol."},{"key":"ref93","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.617473","article-title":"Inhibition of biofilm formation and related gene expression of Listeria monocytogenes by natural antimicrobial compounds","author":"V\u00e1zquez- Armenta","year":"2020","journal-title":"Front. Microbiol."},{"key":"ref94","doi-asserted-by":"publisher","first-page":"232","DOI":"10.3390\/microorganisms12020232","article-title":"The role of flagellum and flagellum-based motility on salmonella Enteritidis and Escherichia coli biofilm formation","volume":"12","author":"Vilas Boas","year":"2024","journal-title":"Microorganisms"},{"key":"ref95","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1186\/s12866-023-03006-5","article-title":"The influence of stress factors on selected phenotypic and genotypic features of Listeria monocytogenes - a pilot study","volume":"23","author":"Wiktorczyk-Kapischke","year":"2023","journal-title":"BMC Microbiology."},{"key":"ref96","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.femsle.2005.09.011","article-title":"Response regulator DegU of Listeria monocytogenes regulates the expression of flagella specific genes","volume":"252","author":"Williams","year":"2005","journal-title":"FEMS Microbiol. Lett."},{"key":"ref97","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s00248-013-0347-4","article-title":"Unraveling Microbial Biofilms of Importance for Food Microbiology","volume":"68","author":"Winkelstr\u00f6ter","year":"2014","journal-title":"Microb. 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