{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T02:58:39Z","timestamp":1779245919292,"version":"3.51.4"},"reference-count":67,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Human immunodeficiency virus (HIV) infection remains a significant global health challenge, with Kaposi\u2019s sarcoma (KS) being one of the most common AIDS-defining cancers. This study aimed to investigate the development of HIV and KS (HIV-KS) research through bibliometric analysis and to assess the current literature to advance the field.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We gathered 1,568 publications on HIV-KS from the Web of Science Core Collection and analyzed them to visualize the data, identifying future directions and emerging trends by CiteSpace software. Betweenness centrality, count, and burst value were used as metrics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The number of publications on HIV-KS fluctuated in the included literature. The most important contributions from countries and institutions were the United States and the National Institutes of Health (NIH) \u2013 USA, respectively. Denise Whitby was the most prolific author, while Yuan Chang had the highest cocitation count. The most commonly cited article is \u201cKaposi sarcoma (2019).\u201d The hotspots in this field are \u201cbasic mechanism,\u201d \u201cKaposi\u2019s sarcoma-associated herpesvirus-related disease,\u201d and \u201ctreatment measures.\u201d The present research direction of HIV-KS is focused on exploring the emerging prevalence, diagnostic methods, and therapeutics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study outlines the current landscape and emerging hotspots of HIV-KS research, offering insights into thematic evolution and collaboration patterns. By identifying key research priorities and structural gaps, the findings can inform future scientific directions, guide resource allocation, and support more context-sensitive strategies for the diagnosis, treatment, and prevention of HIV-KS.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmicb.2025.1601245","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T05:25:24Z","timestamp":1750829124000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Global research landscape of HIV and Kaposi\u2019s sarcoma: a visualized bibliometric analysis"],"prefix":"10.3389","volume":"16","author":[{"given":"Shengwei","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuannan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1097\/QCO.0000000000000213","article-title":"Kaposi\u2019s sarcoma-associated herpesvirus: the role of lytic replication in targeted therapy","volume":"28","author":"Andrei","year":"2015","journal-title":"Curr. Opin. Infect. Dis."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1172\/JCI44417","article-title":"Kaposi sarcoma herpesvirus (KSHV) vFLIP oncoprotein induces B cell transdifferentiation and tumorigenesis in mice","volume":"121","author":"Ballon","year":"2011","journal-title":"J. Clin. Invest."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"2709","DOI":"10.3390\/v14122709","article-title":"Co-infection of the Epstein\u2013Barr virus and the Kaposi sarcoma-associated herpesvirus","volume":"14","author":"B\u00f6ni","year":"2022","journal-title":"Viruses"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e2024150","DOI":"10.5826\/dpc.1402a150","article-title":"Efficacy of long-pulsed Nd:YAG laser for classic Kaposi\u2019s sarcoma: a dermoscopic study","volume":"14","author":"Bostanc\u0131","year":"2024","journal-title":"Dermatol. Pract. Concept."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1097\/00002030-200402200-00015","article-title":"Short-and long-term effects of highly active antiretroviral therapy on Kaposi sarcoma-associated herpesvirus immune responses and viraemia","volume":"18","author":"Bourboulia","year":"2004","journal-title":"AIDS"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/BF02016680","article-title":"Toward a definition of \u201cbibliometrics\u201d","volume":"12","author":"Broadus","year":"1987","journal-title":"Scientometrics"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.jcv.2016.02.019","article-title":"HHV-8 DNA replication correlates with the clinical status in AIDS-related Kaposi\u2019s sarcoma","volume":"78","author":"Broccolo","year":"2016","journal-title":"J. Clin. Virol."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"109056","DOI":"10.1016\/j.celrep.2021.109056","article-title":"KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV\/EBV dual infection","volume":"35","author":"Caduff","year":"2021","journal-title":"Cell Rep."},{"key":"ref9","year":""},{"key":"ref10","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1002\/ijc.28923","article-title":"KSHV-associated multicentric Castleman disease: a tangle of different entities requiring multitarget treatment strategies","volume":"137","author":"Carbone","year":"2015","journal-title":"Int. J. Cancer"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"e220200","DOI":"10.1590\/0074-02760220200","article-title":"Family Herpesviridae and neuroinfections: current status and research in progress","volume":"117","author":"Carneiro","year":"2022","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"7488","DOI":"10.26355\/eurrev_201909_18860","article-title":"The treatment of Kaposi\u2019s sarcoma: present and future options, a review of the literature","volume":"23","author":"Ceccarelli","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1182\/blood.2020005470","article-title":"KSHV\/HHV8-mediated hematologic diseases","volume":"139","author":"Cesarman","year":"2022","journal-title":"Blood"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1056\/NEJM199505043321802","article-title":"Kaposi\u2019s sarcoma\u2013associated herpesvirus-like DNA sequences in AIDS-related body-cavity\u2013based lymphomas","volume":"332","author":"Cesarman","year":"1995","journal-title":"N. Engl. J. Med."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/s41572-019-0060-9","article-title":"Kaposi sarcoma","volume":"5","author":"Cesarman","year":"2019","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"5303","DOI":"10.1073\/pnas.0307513100","article-title":"Searching for intellectual turning points: progressive knowledge domain visualization","volume":"101","author":"Chen","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1002\/asi.20317","article-title":"CiteSpace II: detecting and visualizing emerging trends and transient patterns in scientific literature","volume":"57","author":"Chen","year":"2006","journal-title":"J. Am. Soc. Inf. Sci."},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1374582","DOI":"10.3389\/fmicb.2024.1374582","article-title":"Development and emerging trends of drug resistance mutations in HIV: a bibliometric analysis based on CiteSpace","volume":"15","author":"Chen","year":"2024","journal-title":"Front. Microbiol."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1099132","DOI":"10.3389\/fmicb.2023.1099132","article-title":"Knowledge domain and emerging trends in HIV pre-exposure prophylaxis: a visualization analysis via CiteSpace","volume":"14","author":"Chen","year":"2023","journal-title":"Front. Microbiol."},{"key":"ref20","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1089\/omi.2021.0098","article-title":"What to do for increasing Cancer burden on the African continent? Accelerating public health diagnostics innovation for prevention and early intervention on cancers","volume":"25","author":"Dzobo","year":"2021","journal-title":"OMICS"},{"key":"ref7002","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1002\/ijc.23487","article-title":"Cancer risk in people infected with human immunodeficiency virus in the United States","volume":"123","author":"Engels","year":"2008","journal-title":"Int J Cancer"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/j.biopha.2014.04.010","article-title":"Drug\u2013drug interactions in HIV positive cancer patients","volume":"68","author":"Flepisi","year":"2014","journal-title":"Biomed. Pharmacother."},{"key":"ref22","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1016\/j.ejca.2007.01.028","article-title":"Cancer incidence in AIDS patients in Catalonia, Spain","volume":"43","author":"Galceran","year":"2007","journal-title":"Eur. J. Cancer"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1057\/s41599-021-00718-9","article-title":"A bibliometric study of research topics, collaboration, and centrality in the iterated prisoner\u2019s dilemma","volume":"8","author":"Glynatsi","year":"2021","journal-title":"Humanit. Soc. Sci. Commun."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1177\/10781552221148417","article-title":"Changing therapeutic landscape in advanced kaposi sarcoma: current state and future directions","volume":"29","author":"Goff","year":"2023","journal-title":"J. Oncol. Pharm. Pract."},{"key":"ref7004","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1097\/QAD.0000000000001567","article-title":"HIV-associated kaposi sarcoma and related diseases","volume":"31","author":"Goncalves","year":"2017","journal-title":"Aids"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1007\/s00203-023-03624-7","article-title":"Development trends of immune activation during HIV infection in recent three decades: a bibliometric analysis based on CiteSpace","volume":"205","author":"Gong","year":"2023","journal-title":"Arch. Microbiol."},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1870","DOI":"10.3390\/v16121870","article-title":"Rewriting viral fate: epigenetic and transcriptional dynamics in KSHV infection","volume":"16","author":"Han","year":"2024","journal-title":"Viruses"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1969","DOI":"10.1097\/QAD.0000000000003333","article-title":"Characteristics of patients admitted to the intensive care unit with Kaposi sarcoma herpesvirus-associated diseases","volume":"36","author":"Hansen","year":"2022","journal-title":"AIDS"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"e495","DOI":"10.1016\/S2352-3018(17)30125-X","article-title":"Cancer risk in HIV-infected people in the USA from 1996 to 2012: a population-based, registry-linkage study","volume":"4","author":"Hern\u00e1ndez-Ram\u00edrez","year":"2017","journal-title":"Lancet HIV"},{"key":"ref29","year":""},{"key":"ref30","doi-asserted-by":"publisher","first-page":"6208","DOI":"10.3390\/cancers13246208","article-title":"Kaposi\u2019s sarcoma-associated herpesvirus, the etiological agent of all epidemiological forms of Kaposi\u2019s sarcoma","volume":"13","author":"Jary","year":"2021","journal-title":"Cancers (Basel)"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"ofad160","DOI":"10.1093\/ofid\/ofad160","article-title":"High seroprevalence of Kaposi sarcoma\u2013associated herpesvirus in men who have sex with men with HIV in the southern United States","volume":"10","author":"Knights","year":"2023","journal-title":"Open Forum Infect. Dis."},{"key":"ref32","doi-asserted-by":"publisher","first-page":"5743","DOI":"10.2147\/DDDT.S494758","article-title":"Bibliometric analysis of curcumin based on CiteSpace: landscapes, hotspots, and frontiers","volume":"18","author":"Lai","year":"2024","journal-title":"Drug Des. Devel. Ther."},{"key":"ref33","doi-asserted-by":"publisher","first-page":"9974","DOI":"10.1038\/s41598-022-14170-5","article-title":"Nationwide population-based incidence of cancer among patients with HIV\/AIDS in South Korea","volume":"12","author":"Lee","year":"2022","journal-title":"Sci. Rep."},{"key":"ref34","doi-asserted-by":"publisher","first-page":"e0060424","DOI":"10.1128\/jvi.00604-24","article-title":"LKB1 suppresses KSHV reactivation and promotes primary effusion lymphoma progression","volume":"98","author":"Li","year":"2024","journal-title":"J. Virol."},{"key":"ref35","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/s12879-023-08028-y","article-title":"Seroprevalence and risk factors for Kaposi\u2019s sarcoma associated herpesvirus among men who have sex with men in Shanghai, China","volume":"23","author":"Li","year":"2023","journal-title":"BMC Infect. Dis."},{"key":"ref36","doi-asserted-by":"publisher","first-page":"713","DOI":"10.3390\/diagnostics12030713","article-title":"Primary effusion lymphoma: a timely review on the association with HIV, HHV8, and EBV","volume":"12","author":"Liu","year":"2022","journal-title":"Diagnostics (Basel)"},{"key":"ref7003","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1182\/blood-2019-01-893339","article-title":"Viral, immunologic, and clinical features of primary effusion lymphoma","volume":"133","author":"Lurain","year":"2019","journal-title":"Blood"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"e0002223","DOI":"10.1128\/cmr.00022-23","article-title":"HIV-associated cancers and lymphoproliferative disorders caused by Kaposi sarcoma herpesvirus and Epstein-Barr virus","volume":"37","author":"Lurain","year":"2024","journal-title":"Clin. Microbiol. Rev."},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1044426","DOI":"10.3389\/fpubh.2023.1044426","article-title":"Knowledge domain and emerging trends in HIV-MTB co-infection from 2017 to 2022: a scientometric analysis based on VOSviewer and CiteSpace","volume":"11","author":"M","year":"2023","journal-title":"Front. Public Health"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"13782","DOI":"10.1038\/s41598-024-64533-3","article-title":"Rapid, equipment-free extraction of DNA from skin biopsies for point-of-care diagnostics","volume":"14","author":"Manning","year":"2024","journal-title":"Sci. Rep."},{"key":"ref40","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1038\/nrc2888","article-title":"Kaposi\u2019s sarcoma herpesvirus\/human herpesvirus-8 (KSHV\/HHV8), and the oncogenesis of Kaposi\u2019s sarcoma","volume":"10","author":"Mesri","year":"2010","journal-title":"Nat. Rev. Cancer"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.chom.2014.02.011","article-title":"Human viral Oncogenesis: a cancer hallmarks analysis","volume":"15","author":"Mesri","year":"2014","journal-title":"Cell Host Microbe"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.semcancer.2013.11.001","article-title":"The conundrum of causality in tumor virology: the cases of KSHV and MCV","volume":"26","author":"Moore","year":"2014","journal-title":"Semin. Cancer Biol."},{"key":"ref7005","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1097\/QAI.0b013e318251aedd","article-title":"A randomized controlled trial of highly active antiretroviral therapy versus highly active antiretroviral therapy and chemotherapy in therapy-naive patients with HIV-associated kaposi sarcoma in South Africa","volume":"60","author":"Mosam","year":"2012","journal-title":"JAIDS"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"104494","DOI":"10.1016\/j.jddst.2023.104494","article-title":"Nanoscale drug delivery systems for cancer therapy using paclitaxel\u2014 a review of challenges and latest progressions","volume":"84","author":"Mustafa","year":"2023","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref44","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1053\/j.semdp.2017.04.010","article-title":"Immune reconstitution inflammatory syndrome (IRIS): what pathologists should know","volume":"34","author":"Nelson","year":"2017","journal-title":"Semin. Diagn. Pathol."},{"key":"ref7006","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1093\/cid\/civ996","article-title":"Clinical features and outcomes of patients with symptomatic kaposi sarcoma herpesvirus (KSHV)-associated inflammation: Prospective characterization of KSHV inflammatory cytokine syndrome (KICS)","volume":"62","author":"Polizzotto","year":"2016","journal-title":"Clin. Infect. Dis."},{"key":"ref45","doi-asserted-by":"publisher","first-page":"17572","DOI":"10.1038\/s41598-023-44800-5","article-title":"Prognostic analysis of cutaneous Kaposi sarcoma based on a competing risk model","volume":"13","author":"Qian","year":"2023","journal-title":"Sci. Rep."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1097\/QCO.0000000000000122","article-title":"Facing up to the ongoing challenge of Kaposi\u2019s sarcoma","volume":"28","author":"Robey","year":"2015","journal-title":"Curr. Opin. Infect. Dis."},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.3390\/cancers16071295","article-title":"Electrochemotherapy in kaposi\u2019s sarcoma patients: from the gold standard strategy to locally advanced cutaneous and subcutaneous lesions","volume":"16","author":"Rullo","year":"2024","journal-title":"Cancers"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1128\/CVI.00673-12","article-title":"Development of whole-virus multiplex luminex-based serological assays for diagnosis of infections with Kaposi\u2019s sarcoma-associated herpesvirus\/human herpesvirus 8 homologs in macaques","volume":"20","author":"Ryan","year":"2013","journal-title":"Clin. Vaccine Immunol."},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1387","DOI":"10.1093\/infdis\/jiad384","article-title":"Prevalence, incidence, and predictors of Kaposi sarcoma\u2013associated herpesvirus infection among young men who have sex with men in the southern United States","volume":"229","author":"Salyards","year":"2024","journal-title":"J. Infect. Dis."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"161","DOI":"10.4149\/av_2011_02_161","article-title":"Increased prevalence of Kaposi\u2019s sarcoma-associated herpesvirus in the Kaposi\u2019s sarcoma-endemic area of Western Kenya in 1981\u20132000","volume":"55","author":"Senba","year":"2011","journal-title":"Acta Virol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"7720","DOI":"10.1093\/nar\/gkae540","article-title":"High-density resolution of the Kaposi\u2019s sarcoma associated herpesvirus transcriptome identifies novel transcript isoforms generated by long-range transcription and alternative splicing","volume":"52","author":"Shekhar","year":"2024","journal-title":"Nucleic Acids Res."},{"key":"ref7001","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1093\/jnci\/djr076","article-title":"Cancer burden in the HIV-infected population in the United States","volume":"103","author":"Shiels","year":"2011","journal-title":"J. Natl. Cancer Inst."},{"key":"ref52","doi-asserted-by":"publisher","first-page":"e1011703","DOI":"10.1371\/journal.ppat.1011703","article-title":"Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages","volume":"19","author":"Shimoda","year":"2023","journal-title":"PLoS Pathog."},{"key":"ref53","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.3390\/microorganisms10091754","article-title":"Role of Epitranscriptomic and epigenetic modifications during the lytic and latent phases of herpesvirus infections","volume":"10","author":"Soto","year":"2022","journal-title":"Microorganisms"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"189","DOI":"10.3390\/v16020189","article-title":"Clinical significance of elevated KSHV viral load in HIV-related Kaposi\u2019s sarcoma patients in South Africa","volume":"16","author":"Tibenderana","year":"2024","journal-title":"Viruses"},{"key":"ref7007","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1086\/654798","article-title":"An interleukin-6-related systemic inflammatory syndrome in patients co-infected with kaposi sarcoma-associated herpesvirus and HIV but without multicentric castleman disease","volume":"51","author":"Uldrick","year":"2010","journal-title":"Clin Infect Dis"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"484","DOI":"10.3390\/cancers14030484","article-title":"Therapeutic perspectives in the systemic treatment of Kaposi\u2019s sarcoma","volume":"14","author":"Valantin","year":"2022","journal-title":"Cancers (Basel)"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"9862","DOI":"10.1093\/nar\/gku583","article-title":"HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN\/AKT\/mTOR signaling pathway","volume":"42","author":"Xue","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"ref57","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1056\/NEJMra1615896","article-title":"HIV-associated cancers and related diseases","volume":"378","author":"Yarchoan","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"ref58","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.2147\/IDR.S456286","article-title":"Nab-paclitaxel for relapsed AIDS-related Kaposi sarcoma-a case report","volume":"17","author":"Yu","year":"2024","journal-title":"Infect Drug Resist."},{"key":"ref59","doi-asserted-by":"publisher","first-page":"1568022","DOI":"10.3389\/fneur.2025.1568022","article-title":"Mapping the intersection of HIV and alzheimer\u2019s disease: a bibliometric analysis of emerging research trends","volume":"16","author":"Zhang","year":"2025","journal-title":"Front. Neurol."},{"key":"ref60","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1016\/j.jmb.2011.03.055","article-title":"Human immunodeficiency virus type 1 induces lytic cycle replication of Kaposi\u2019s-sarcoma-associated herpesvirus: role of Ras\/c-Raf\/MEK1\/2, PI3K\/AKT, and NF-\u03baB signaling pathways","volume":"410","author":"Zhu","year":"2011","journal-title":"J. Mol. Biol."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2025.1601245\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T05:25:25Z","timestamp":1750829125000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2025.1601245\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,25]]},"references-count":67,"alternative-id":["10.3389\/fmicb.2025.1601245"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2025.1601245","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,25]]},"article-number":"1601245"}}