{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:40:47Z","timestamp":1791337247018,"version":"4.3.1"},"reference-count":55,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>Probiotics have demonstrated broad prospects in maintaining human health, and complete genome analysis enables unveiling the intrinsic probiotic mechanisms. In this study, the probiotic properties of <jats:italic>Lactiplantibacillus plantarum<\/jats:italic> BGI-J9 (BGI-J9) were explored via integrating complete genomic and phenotypic analysis. Results indicated that the high-quality complete genome of BGI-J9 comprises 3,128,867 bp with 2,926 coding sequences and an average GC content of 45%. Genomic annotation analysis revealed that BGI-J9 harbored <jats:italic>nhaK<\/jats:italic>, <jats:italic>plsC<\/jats:italic>, <jats:italic>pyk<\/jats:italic>, <jats:italic>atp<\/jats:italic>, <jats:italic>opp<\/jats:italic>, <jats:italic>rps<\/jats:italic>, <jats:italic>rpl<\/jats:italic>, <jats:italic>rpm<\/jats:italic> system genes, as well as plantaricin, glutathione peroxidase family, glutathione, catalase, thioredoxin encoding genes, and exhibited favorable gastrointestinal tolerance, antimicrobial activity, antioxidant activity in <jats:italic>in vitro<\/jats:italic> assays. Notably, alcohol degradation enzyme genes were identified in the BGI-J9 genome, which accounted for the potent <jats:italic>in vitro<\/jats:italic> alcohol dehydrogenase and acetaldehyde dehydrogenase activities and alcohol degradation capacity exhibited by BGI-J9. These findings indicated that BGI-J9 has the potential to assist in promoting alcohol degradation and mitigating alcohol-induced damage. In conclusion, this study first presented the complete genome of BGI-J9, furnishing a theoretical basis for its application in alleviating alcohol damage.<\/jats:p>","DOI":"10.3389\/fmicb.2025.1664033","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T05:39:22Z","timestamp":1757396362000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Revealing the potent probiotic properties and alcohol degradation capabilities of Lactiplantibacillus plantarum BGI-J9 by combining complete genomic and phenotypic analysis"],"prefix":"10.3389","volume":"16","author":[{"given":"Yaqi","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihui","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benliang","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangfeng","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhinan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haifeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiyi","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanqiang","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/bs.vh.2022.09.002","article-title":"The antioxidant glutathione","volume":"121","author":"Averill-Bates","year":"2023","journal-title":"Vitam. 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