{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T08:11:14Z","timestamp":1771920674040,"version":"3.50.1"},"reference-count":63,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Scientific and Technological Innovation Team for Qinghai-Tibetan Plateau Research in Southwest Minzu University","award":["2024CXTD13"],"award-info":[{"award-number":["2024CXTD13"]}]},{"name":"Fundamental Research Funds for the Central Universities, Southwest Minzu University","award":["ZYN2024043"],"award-info":[{"award-number":["ZYN2024043"]}]},{"name":"Sichuan Science and Technology Program","award":["2024ZHXC0001"],"award-info":[{"award-number":["2024ZHXC0001"]}]},{"name":"Sichuan Science and Technology Program","award":["2024NSFSC0029"],"award-info":[{"award-number":["2024NSFSC0029"]}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Chinese herbal medicines, including honeysuckle (Lonicera japonica), exhibit diverse beneficial properties and are increasingly being explored as feed additives in livestock production to improve animal health and product quality. This study investigates the effects of honeysuckle vine powder (HVP) supplementation as an herbal feed additive on growth performance, immune function, and rumengut microbiota in Nanjiang Yellow goats during fattening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We evaluated four dietary groups: control (basal diet) and three experimental groups supplemented with 1% (EG1), 1.5% (EG2), and 2% HVP (EG3) for 60 days. After sampling, we measured the blood biochemical, immune indicators and carried out 16s RNA sequencing of rumen and gut microbiota for Nanjiang Yellow goat samples.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We evaluated four dietary groups: control (basal diet) and three experimental groups supplemented with 1% (EG1), 1.5% (EG2), and 2% HVP (EG3) for 60\u202fdays. Results demonstrated that 2% HVP significantly enhanced, average daily gain (\u0394ADG\u202f=\u202f0.05\u202f\u00b1\u202f0.02 \/kg,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05,\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f8), and feed conversion rate (\u0394FCR\u202f=\u202f5.26\u202f\u00b1\u202f0.69,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05,\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f8), while improving body length and chest circumference. Serum immunoglobulin (IgG, IgM) levels were elevated, indicating strengthened systemic immunity (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.05). Critically, 16S rRNA analysis revealed HVP-induced rumen and gut microbiota restructuring, characterized by increased Firmicutes abundance.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>These findings validate HVP as a sustainable feed additive that optimizes productivity and immune resilience through microbiota-host crosstalk, supporting its application in ecofriendly livestock farming.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmicb.2025.1727133","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T06:31:16Z","timestamp":1768372276000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of honeysuckle vine powder on growth, immune performance, and gastrointestinal microbiota structure of Nanjiang Yellow goats"],"prefix":"10.3389","volume":"16","author":[{"given":"Kerui","family":"Li","sequence":"first","affiliation":[{"name":"Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Key Laboratory of Sichuan Province","place":["Chengdu, China"]},{"name":"Bazhong Academy of Agriculture and Forestry Sciences","place":["Bazhong, Sichuan, China"]},{"name":"College of Life Sciences and Agri-forestry, Southwest University of Science and Technology","place":["Mianyang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lian","family":"Huang","sequence":"additional","affiliation":[{"name":"Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Key Laboratory of Sichuan Province","place":["Chengdu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changhui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Key Laboratory of Sichuan Province","place":["Chengdu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Xiang","sequence":"additional","affiliation":[{"name":"Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Key Laboratory of Sichuan Province","place":["Chengdu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang","family":"Jiang","sequence":"additional","affiliation":[{"name":"Institute of Nanjiang Yellow Goat Sciences","place":["Bazhong, Sichuan, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wangsheng","family":"Zhao","sequence":"additional","affiliation":[{"name":"College of Life Sciences and Agri-forestry, Southwest University of Science and Technology","place":["Mianyang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hengbo","family":"Shi","sequence":"additional","affiliation":[{"name":"Institute of Dairy Science, College of Animal Sciences, Zhejiang University","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangjiang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Key Laboratory of Sichuan Province","place":["Chengdu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhanyu","family":"Du","sequence":"additional","affiliation":[{"name":"Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization Key Laboratory of Sichuan Province","place":["Chengdu, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"103454","DOI":"10.1016\/j.psj.2024.103454","article-title":"Effects of varying dietary microalgae levels on performance, egg quality, fertility, and blood biochemical parameters of laying Japanese quails (Coturnix coturnix japonica)","volume":"103","author":"Abd El-Hack","year":"2024","journal-title":"Poult. 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