{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T16:03:23Z","timestamp":1780589003688,"version":"3.54.1"},"reference-count":70,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>\n                    The prospective use of sludge compost for restoring depleted soils requires balancing its agronomic benefits against potential ecological risks. This study employed an integrated metagenomic and metabolomic approach to evaluate the dose-dependent effects of sludge compost on soil properties, maize growth, and rhizosphere microbial communities. Results showed that moderate compost application (\u226415% w\/w) enhanced soil nutrient availability, promoted root development, and enriched beneficial microbial taxa (\n                    <jats:italic>Streptomyces, Mesorhizobium, Flavisolibacter<\/jats:italic>\n                    ), while upregulating plant stress-response metabolites (terpenoids, flavonoids). Conversely, excessive application (&amp;gt;20%) induced salinity stress, impaired root growth, and altered the microbial community, favoring thermophilic and xenobiotic-metabolizing taxa. Critically, high application rates led to the accumulation of residual pharmaceuticals (anti-neoplastic and anti-epileptic agents) and pesticides (insecticides and rodenticides), which correlated with the enrichment of microbial pathways associated with human diseases, highlighting a significant ecological risk. In addition, root integrity was the primary determinant of a sustainable plant-microbe feedback loop. These findings underscore the necessity for tailored application strategies to harness the soil-restorative potential of sludge compost while mitigating contaminant-driven risks, providing a framework for its safe use in sustainable agriculture.\n                  <\/jats:p>","DOI":"10.3389\/fmicb.2026.1731456","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T13:41:15Z","timestamp":1779457275000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Sludge compost: a double-edged sword for depleted soil restoration revealed by integrated multi-omics analysis"],"prefix":"10.3389","volume":"17","author":[{"given":"Xiaojie","family":"Mei","sequence":"first","affiliation":[{"name":"Shanghai Investigation, Design & Research Institute Co. Ltd.","place":["Shanghai, China"]},{"name":"China Three Gorges Corporation, National Engineering Research Center of Eco-Environment in the Yangtze River Economic Belt","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqing","family":"Wu","sequence":"additional","affiliation":[{"name":"Shanghai Investigation, Design & Research Institute Co. Ltd.","place":["Shanghai, China"]},{"name":"China Three Gorges Corporation, National Engineering Research Center of Eco-Environment in the Yangtze River Economic Belt","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Fang","sequence":"additional","affiliation":[{"name":"Shanghai Investigation, Design & Research Institute Co. 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Ecol."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1002\/cbdv.200490060","article-title":"Chemistry and biodiversity of the biologically active natural glycosides","volume":"1","author":"Dembitsky","year":"2004","journal-title":"Chem. Biodivers."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"fny219","DOI":"10.1093\/femsle\/fny219","article-title":"Specific detection of Lysobacter antibioticus strains in agricultural soil using PCR and real-time PCR","volume":"365","author":"Fu","year":"2018","journal-title":"FEMS Microbiol. Lett."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"11","DOI":"10.11838\/sfsc.1673-6257.22547","article-title":"Effects of partial substitution of chemical fertilizer with organic fertilizer on soil organic nitrogen and active nitrogen","volume":"10","author":"Gao","year":"2023","journal-title":"Soil Fertilizer Sci China"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/bf02051248","article-title":"On the interaction in culture between two pathogenic soil-inhabiting fungi","volume":"19","author":"Gayed","year":"1963","journal-title":"Mycopathol. Mycol. Appl."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1002\/saj2.20203","article-title":"Predicting soil organic matter nitrogen mineralization","volume":"85","author":"Gilmour","year":"2021","journal-title":"Soil Sci. Soc. Am. J."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"fnaa024","DOI":"10.1093\/femsle\/fnaa024","article-title":"Diversity of a phosphate transporter gene among species and isolates of arbuscular mycorrhizal fungi","volume":"367","author":"Giovannini","year":"2020","journal-title":"FEMS Microbiol. Lett."},{"key":"ref12","doi-asserted-by":"publisher","first-page":"126885","DOI":"10.1016\/j.micres.2021.126885","article-title":"Mycolicibacterium sp. strain PAM1, an alfalfa rhizosphere dweller, catabolizes PAHs and promotes partner-plant growth","volume":"253","author":"Golubev","year":"2021","journal-title":"Microbiol. Res."},{"key":"ref13","year":"2024"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jhazmat.2009.03.137","article-title":"Biodegradation aspects of polycyclic aromatic hydrocarbons (PAHs): a review","volume":"169","author":"Haritash","year":"2009","journal-title":"J. Hazard. Mater."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1800","DOI":"10.1080\/13102818.2021.2020162","article-title":"Research progress in biosynthesis and regulation of plant terpenoids","volume":"35","author":"Huang","year":"2021","journal-title":"Biotechnol. Biotechnol. Equip."},{"key":"ref16","doi-asserted-by":"publisher","first-page":"128704","DOI":"10.1016\/j.jclepro.2021.128704","article-title":"Biostimulants in bioconversion compost of organic waste: a novel booster in sustainable agriculture","volume":"319","author":"Huang","year":"2021","journal-title":"J. Clean. Prod."},{"key":"ref17","doi-asserted-by":"publisher","first-page":"15001","DOI":"10.1021\/acs.est.1c06194","article-title":"Does the EU'S action plan for a circular economy challenge the linear economy?","volume":"55","author":"Johansson","year":"2021","journal-title":"Environ. Sci. 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Microbiol."},{"key":"ref27","doi-asserted-by":"publisher","first-page":"125047","DOI":"10.1016\/j.biortech.2021.125047","article-title":"Research on microbial structures, functions and metabolic pathways in an advanced denitrification system coupled with aerobic methane oxidation based on metagenomics","volume":"332","author":"Liu","year":"2021","journal-title":"Bioresour. Technol."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"5756","DOI":"10.1002\/jsfa.9125","article-title":"Antagonistic activities of volatiles produced by two Bacillus strains against Monilinia fructicola in peach fruit","volume":"98","author":"Liu","year":"2018","journal-title":"J. Sci. 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Res."},{"key":"ref45","doi-asserted-by":"publisher","first-page":"15016781","DOI":"10.4238\/gmr.15016781","article-title":"Process of Bipolaris sorghicola invasion of host cells","volume":"15","author":"Peng","year":"2016","journal-title":"Genet. Mol. Res."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"2213","DOI":"10.1038\/s41598-023-29134-6","article-title":"Co-cultivation of Mortierellaceae with Pseudomonas helmanticensis affects both their growth and volatilome","volume":"13","author":"Probst","year":"2023","journal-title":"Sci. Rep."},{"key":"ref47","doi-asserted-by":"publisher","first-page":"uhac138","DOI":"10.1093\/hr\/uhac138","article-title":"Identification of UDP-rhamnosyltransferases and UDP-galactosyltransferase involved in flavonol glycosylation in Morella rubra","volume":"9","author":"Ren","year":"2022","journal-title":"Hortic. Res."},{"key":"ref48","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.drup.2016.07.003","article-title":"Antibiotic resistance in Burkholderia species","volume":"28","author":"Rhodes","year":"2016","journal-title":"Drug Resist. Update."},{"key":"ref49","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.wasman.2017.08.012","article-title":"Compost supplementation with nutrients and microorganisms in composting process","volume":"69","author":"Sanchez","year":"2017","journal-title":"Waste Manag."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"104670","DOI":"10.1016\/j.pestbp.2020.104670","article-title":"Antifungal and antioomycete activities and modes of action of isobenzofuranones isolated from the endophytic fungus Hypoxylon anthochroum strain Gseg1","volume":"169","author":"Sanchez-Fernandez","year":"2020","journal-title":"Pestic. Biochem. Physiol."},{"key":"ref51","doi-asserted-by":"publisher","first-page":"595","DOI":"10.3390\/agronomy9100595","article-title":"Serendipita species trigger cultivar-specific responses to fusarium wilt in tomato","volume":"9","author":"Sefloo","year":"2019","journal-title":"Agronomy Basel"},{"key":"ref52","volume-title":"Analysis Methods of water Soluble Salts of Forest Soil (LY\/T 1251\u20131999)","year":""},{"key":"ref53","volume-title":"Determination of pH Value in Forest Soil (LY\/T 1239\u20131999)","year":""},{"key":"ref54","volume-title":"Nitrogen Determination Methods of Forest Soils (LY\/T 1228\u20132015)","year":""},{"key":"ref55","volume-title":"Potassium Determination Methods of Forest Soils (LY\/T 1234\u20132015)","year":""},{"key":"ref56","doi-asserted-by":"publisher","first-page":"575","DOI":"10.14348\/molcells.2014.0141","article-title":"Strategies for improving potassium use efficiency in plants","volume":"37","author":"Shin","year":"2014","journal-title":"Mol. Cells"},{"key":"ref57","volume-title":"Planting Soil for Greening (CJT 340\u20132016)","year":"2016"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1006\/mpev.2000.0775","article-title":"Molecular phylogeny of parasitic Zygomycota (Dimargaritales, Zoopagales) based on nuclear small subunit ribosomal DNA sequences","volume":"16","author":"Tanabe","year":"2000","journal-title":"Mol. Phylogenet. Evol."},{"key":"ref59","doi-asserted-by":"publisher","first-page":"e0040122","DOI":"10.1128\/aem.00401-22","article-title":"Development of a markerless deletion mutagenesis system in nitrate-reducing bacterium Rhodanobacter denitrificans","volume":"88","author":"Tao","year":"2022","journal-title":"Appl. Environ. Microbiol."},{"key":"ref60","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/s00572-008-0161-x","article-title":"Diversity and infectivity of arbuscular mycorrhizal fungi in agricultural soils of the Sichuan Province of mainland China","volume":"18","author":"Wang","year":"2008","journal-title":"Mycorrhiza"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.jbiotec.2010.09.433","article-title":"Exploration of potential xenobiotic reductases from soil bacteria Streptomyces","volume":"150","author":"Xie","year":"2010","journal-title":"J. Biotechnol."},{"key":"ref62","doi-asserted-by":"publisher","first-page":"2215","DOI":"10.1111\/pce.13554","article-title":"Rice sulfoquinovosyltransferase SQD2.1 mediates flavonoid glycosylation and enhances tolerance to osmotic stress","volume":"42","author":"Zhan","year":"2019","journal-title":"Plant Cell Environ."},{"key":"ref63","doi-asserted-by":"publisher","first-page":"671","DOI":"10.3390\/jof8070671","article-title":"New Arthrobotrys nematode-trapping species (Orbiliaceae) from terrestrial soils and freshwater sediments in China","volume":"8","author":"Zhang","year":"2022","journal-title":"J. Fungi"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"38","DOI":"10.13320\/j.cnki.jauh.2018.0123","article-title":"Study on microbial community structure and diversity of Morchella rhizosphere soil","volume":"41","author":"Zhang","year":"2018","journal-title":"J. Agric. Uni. Hebei"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1094\/pdis-09-22-2196-re","article-title":"Long-term field application of a plant growth-promoting rhizobacterial consortium suppressed root-knot disease by shaping the rhizosphere microbiota","volume":"108","author":"Zhang","year":"2024","journal-title":"Plant Dis."},{"key":"ref66","doi-asserted-by":"publisher","first-page":"117734","DOI":"10.1016\/j.ecoenv.2025.117734","article-title":"Variations of microbiota and metabolites in rhizosphere soil of Carmona microphylla at the co-contaminated site with polycyclic aromatic hydrocarbons and heavy metals","volume":"290","author":"Zhang","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref67","doi-asserted-by":"publisher","first-page":"176","DOI":"10.13205\/j.hjgc.202109025","article-title":"Application status and prospect of compost in soil remediation and quality improvement","volume":"39","author":"Zhang","year":"2021","journal-title":"Environ. Engin."},{"key":"ref68","doi-asserted-by":"publisher","first-page":"169","DOI":"10.5847\/wjem.j.1920-8642.2013.03.002","article-title":"The Acinetobacter baumannii group: a systemic review","volume":"4","author":"Zhang","year":"2013","journal-title":"World J Emerg Med"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"1207125","DOI":"10.3389\/fmicb.2023.1207125","article-title":"Antibacterial activities of coumarin-3-carboxylic acid against Acidovorax citrulli","volume":"14","author":"Zhu","year":"2023","journal-title":"Front. Microbiol."},{"key":"ref70","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/B978-0-12-417187-9.00002-4","article-title":"Assessment and modeling of soil available phosphorus in sustainable cropping systems","volume":"122","author":"Ziadi","year":"2013","journal-title":"Adv. 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