{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T03:00:34Z","timestamp":1788836434393,"version":"build-2803163510"},"reference-count":43,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Urinary tract infections are among the most frequent healthcare-associated infections and represent a major public health challenge due to their increasing antimicrobial resistance. Data from tertiary-care hospitals in Mexico remain scarce. This study aims to describe prevalence and microbiological profile of healthcare-associated UTIs in a tertiary medical facility in western Mexico.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional study included all UTI cases recorded from January to December 2024. Data was obtained from the institutional epidemiological surveillance platform (INOSO). Descriptive statistics were applied using measures of central tendency, proportions and confidence intervals. Antimicrobial resistance profiles were analyzed using automated Vitek\u00ae testing for Antibiotic susceptibility testing and mass spectrometry for pathogen identification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 376 patients were included (mean age 52.9\u202fyears; 53.2% women). Healthcare-associated UTIs represented 80.6% of cases. Monthly incidence displayed a multimodal pattern with peaks in April and October. Nephrology, Cardiology, and Neurosurgery accounted for &amp;gt;50% of cases. Among 120 isolates, bacteria comprised 70.8%, mainly\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      (35.8%),\n                      <jats:italic>Klebsiella pneumoniae,<\/jats:italic>\n                      and\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      ; fungal isolates (29.2%) were predominantly\n                      <jats:italic>Candida albicans<\/jats:italic>\n                      . Extensive drug resistance was observed in\n                      <jats:italic>Providencia rettgeri<\/jats:italic>\n                      (resistant to all tested antibiotics) and\n                      <jats:italic>Acinetobacter baumannii.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>UTIs in a tertiary-care hospital in Mexico exhibit high prevalence, multimodal temporal dynamics, and alarming antimicrobial resistance. Continuous surveillance, antimicrobial stewardship, and targeted infection-control strategies are urgently needed in high-risk hospital units.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmicb.2026.1734551","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T06:39:53Z","timestamp":1769668793000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Microbiological profile and epidemiological perspective on urinary tract infections (UTIs) in a tertiary medical center in Western Mexico"],"prefix":"10.3389","volume":"17","author":[{"given":"Pedro","family":"Reyes-Martinez","sequence":"first","affiliation":[{"name":"Departamento de Fisiolog\u00eda, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara","place":["Guadalajara, Jalisco, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erick","family":"Sierra-Diaz","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednicas Quir\u00fargicas, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara","place":["Guadalajara, Jalisco, Mexico"]},{"name":"Divisi\u00f3n de Epidemiolog\u00eda, UMAE Hospital de Especialidades Centro M\u00e9dico Nacional de Occidente","place":["Guadalajara, Jalisco, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo Cesar","family":"Ortiz-Lazareno","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n de Inmunolog\u00eda, Centro de Investigaci\u00f3n Biom\u00e9dica de Occidente","place":["Guadalajara, Jalisco, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Garcia-Gutierrez","sequence":"additional","affiliation":[{"name":"Escuela de Medicina y Ciencias de la Salud Tec de Monterrey Campus Guadalajara","place":["Guadalajara, Jalisco, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n","family":"Ram\u00edrez-de-Arellano","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n en C\u00e1ncer e Infecciones, Departamento de Microbiolog\u00eda y patolog\u00eda, Centro Universitario en Ciencias de la Salud, Universidad de Guadalajara","place":["Guadalajara, Jalisco, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Sandoval-Pinto","sequence":"additional","affiliation":[{"name":"Departamento de Biolog\u00eda Celular y Molecular, Centro Universitario de Ciencias Biol\u00f3gicas y Agropecuarias, Universidad de Guadalajara","place":["Zapopan, Jalisco, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Cremades","sequence":"additional","affiliation":[{"name":"Departamento de Microbiolog\u00eda y Parasitolog\u00eda, Centro Universitario en Ciencias de la Salud, Universidad de Guadalajara","place":["Guadalajara, Jalisco, Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2765","DOI":"10.2147\/IDR.S402894","article-title":"Epidemiology and multidrug resistance of Pseudomonas aeruginosa and Acinetobacter baumanni isolated from clinical samples in Ethiopia","volume":"16","author":"Araya","year":"2023","journal-title":"Infect. 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