{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T07:20:29Z","timestamp":1772090429265,"version":"3.50.1"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>\n                    Canine coronavirus (CCoV) is an important enteric alphacoronavirus primarily affecting canids. Here, we detected canine coronavirus RNA in a captive 9-year-old Amur tiger (\n                    <jats:italic>Panthera tigris altaica<\/jats:italic>\n                    ) in China. The complete viral genome was obtained using metagenomic next-generation sequencing. Phylogenetic and recombination analyses were then performed to investigate its evolutionary relationship with canine and feline coronaviruses. The identified CCoV strain clustered within established canine coronavirus lineages and showed sequence evidence of recombination involving coronavirus strains previously reported in other carnivore species. Although the detection of viral RNA alone does not establish a causal relationship between CCoV infection and disease outcome, this study provides molecular evidence that Amur tigers are susceptible to canine coronavirus infection. These findings expand the known host range of CCoV and contribute to understanding the evolution and cross-species transmission potential of coronaviruses among carnivores.\n                  <\/jats:p>","DOI":"10.3389\/fmicb.2026.1764349","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T06:53:57Z","timestamp":1772088837000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Cross-species transmission alert: a novel canine-raccoon dog coronavirus infecting an Amur Tiger in China"],"prefix":"10.3389","volume":"17","author":[{"given":"Zhiqiang","family":"Han","sequence":"first","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Jilin Agricultural University","place":["Changchun, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haijun","family":"Wang","sequence":"additional","affiliation":[{"name":"Jilin Provincial Academy of Forestry Sciences","place":["Changchun, China"]},{"name":"Jilin Province Northeast Tiger Garden and Jilin Wild Animal Rescue Breeding Center Committee","place":["Changchun, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Jilin Agricultural University","place":["Changchun, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhige","family":"Tian","sequence":"additional","affiliation":[{"name":"Faculty of Agriculture, Forestry and Food Engineering, Yibin University","place":["Yibin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinglong","family":"Gong","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Jilin Agricultural University","place":["Changchun, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuli","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Jilin University","place":["Changchun, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Li","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Jilin Agricultural University","place":["Changchun, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Du","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Jilin Agricultural University","place":["Changchun, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoliang","family":"Hu","sequence":"additional","affiliation":[{"name":"Faculty of Agriculture, Forestry and Food Engineering, Yibin University","place":["Yibin, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, College of Veterinary Medicine, Jilin Agricultural University","place":["Changchun, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"2159","DOI":"10.1007\/s00705-019-04296-9","article-title":"Molecular characterization of HLJ-073, a recombinant canine coronavirus strain from China with an ORF3abc deletion","volume":"164","author":"Chen","year":"2019","journal-title":"Arch. 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