{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:03:40Z","timestamp":1789625020605,"version":"build-2803163510"},"reference-count":68,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>\n                    Enhanced\n                    <jats:italic>in situ<\/jats:italic>\n                    bioremediation is a widely adopted and sustainable means of remediating chlorinated contaminant impacted groundwater utilizing organohalide respiring bacteria. These bacteria utilize chlorinated compounds as terminal electron acceptors to harvest energy, producing partially or fully dechlorinated end products. A barrier to successful remediation utilizing organohalide respiring bacteria is the impact of environmental factors which may be toxic or otherwise inhibitory towards these organisms or their respiration pathways, particularly in sites with complex contaminant profiles and heterogeneous geochemistry. In this study, groundwater from two regions of a heavily and mixed chlorinated solvent impacted site in Sydney, Australia with minimal historical evidence of natural attenuation was used to establish bench-scale microcosms for identification of factors that modulate successful bioremediation. The results of this study demonstrate that the success of enhanced bioremediation is minimally impacted by initial bacterial abundance with significant degradation of chlorinated hydrocarbons detected in microcosms with as low as 83 16S rRNA gene copies\/mL following enhanced bioremediation, sulfate concentrations exceeding 71\u202fmg\/L may preferentially stimulate sulfate reducing bacteria, while chlorinated hydrocarbon concentration and composition remain the most inhibitory factors limiting bioremediation success.\n                  <\/jats:p>","DOI":"10.3389\/fmicb.2026.1845514","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:31:34Z","timestamp":1789623094000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Bioremediation of complex chlorinated-solvent impacted groundwater"],"prefix":"10.3389","volume":"17","author":[{"given":"Evan","family":"Landers","sequence":"first","affiliation":[{"name":"Department of Civil and Environmental Engineering, University of New South Wales","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering, University of New South Wales","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjith","family":"Rajendran","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering, University of New South Wales","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma Fay","family":"Harding","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering, University of New South Wales","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Picott","sequence":"additional","affiliation":[{"name":"Chemical Engineering and Applied Chemistry, University of Toronto","place":["Toronto, ON, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitra","family":"Parsa","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering, University of New South Wales","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Manefield","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering, University of New South Wales","place":["Sydney, NSW, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1016\/j.scitotenv.2018.07.425","article-title":"Influence of biochars on the accessibility of organochlorine pesticides and microbial community in contaminated soils","volume":"647","author":"Ali","year":"2019","journal-title":"Sci. Total Environ."},{"key":"ref2","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1038\/s41587-019-0209-9","article-title":"Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2","volume":"37","author":"Bolyen","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"ref3","doi-asserted-by":"publisher","first-page":"693","DOI":"10.3389\/fmicb.2014.00693","article-title":"Biofilm growth mode promotes maximum carrying capacity and community stability during product inhibition syntrophy","volume":"5","author":"Brileya","year":"2014","journal-title":"Front. Microbiol."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.1039\/c2em30358b","article-title":"Characterizing the intrinsic bioremediation potential of 1,4-dioxane and trichloroethene using innovative environmental diagnostic tools","volume":"14","author":"Chiang","year":"2012","journal-title":"J. Environ. Monit."},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.31083\/j.fbe1503016","article-title":"Reviewing the bioremediation of contaminants in groundwater: investigations over 40 years provide insights into what's achievable","volume":"15","author":"Davis","year":"2023","journal-title":"Front. Biosci. (Elite Ed.)"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"20642","DOI":"10.1021\/acs.est.4c07445","article-title":"Integrating enzyme-based kinetics in reactive transport models to simulate spatiotemporal dynamics of biomarkers during chlorinated Ethene degradation","volume":"58","author":"Di Curzio","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"2287","DOI":"10.1128\/aem.57.8.2287-2292.1991","article-title":"Reductive dechlorination of high concentrations of tetrachloroethene to ethene by an anaerobic enrichment culture in the absence of methanogenesis","volume":"57","author":"DiStefano","year":"1991","journal-title":"Appl. Environ. Microbiol."},{"key":"ref8","doi-asserted-by":"publisher","first-page":"2254","DOI":"10.1021\/es990638e","article-title":"Bioaugmentation for accelerated in situ anaerobic bioremediation","volume":"34","author":"Ellis","year":"2000","journal-title":"Environ. Sci. Technol."},{"key":"ref9","doi-asserted-by":"publisher","first-page":"129595","DOI":"10.1016\/j.jhazmat.2022.129595","article-title":"A new insight into the influencing factors of natural attenuation of chlorinated hydrocarbons contaminated groundwater: a long-term field study of a retired pesticide site","volume":"439","author":"Fan","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"ref10","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1038\/s41579-019-0158-9","article-title":"Bacteria and archaea on earth and their abundance in biofilms","volume":"17","author":"Flemming","year":"2019","journal-title":"Nat. Rev. Microbiol."},{"key":"ref11","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/2191-0855-3-30","article-title":"Evaluation of the inhibitory effects of chloroform on ortho-chlorophenol- and chloroethene-dechlorinating Desulfitobacterium strains","volume":"3","author":"Futagami","year":"2013","journal-title":"AMB Express"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1007\/s002030050308","article-title":"Desulfitobacterium sp. strain PCE1, an anaerobic bacterium that can grow by reductive dechlorination of tetrachloroethene or ortho-chlorinated phenols","volume":"165","author":"Gerritse","year":"1996","journal-title":"Arch. Microbiol."},{"key":"ref13","doi-asserted-by":"publisher","first-page":"e0125393","DOI":"10.1371\/journal.pone.0125393","article-title":"Biochar in co-contaminated soil manipulates arsenic solubility and microbiological community structure, and promotes organochlorine degradation","volume":"10","author":"Gregory","year":"2015","journal-title":"PLoS One"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.jconhyd.2013.04.002","article-title":"Use of emulsified vegetable oil to support bioremediation of TCE DNAPL in soil columns","volume":"151","author":"Harkness","year":"2013","journal-title":"J. Contam. Hydrol."},{"key":"ref15","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1038\/nature01717","article-title":"Detoxification of vinyl chloride to ethene coupled to growth of an anaerobic bacterium","volume":"424","author":"He","year":"2003","journal-title":"Nature"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.00089","article-title":"Functional genes and bacterial communities during Organohalide respiration of Chloroethenes in microcosms of multi-contaminated groundwater","volume":"10","author":"Hermon","year":"2019","journal-title":"Front. Microbiol."},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3390\/v12101091","article-title":"Phages in anaerobic systems","volume":"12","author":"Hern\u00e1ndez","year":"2020","journal-title":"Viruses"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1508","DOI":"10.1007\/s11356-021-15635-2","article-title":"Key factors controlling microbial distribution on a DNAPL source area","volume":"29","author":"Herrero","year":"2022","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1709","DOI":"10.1038\/s41396-020-00881-y","article-title":"Novel dichloromethane-fermenting bacteria in the Peptococcaceae family","volume":"15","author":"Holland","year":"2021","journal-title":"ISME J."},{"key":"ref20","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1111\/j.1745-6592.2008.00197.x","article-title":"Demonstration of enhanced bioremediation in a TCE source area at launch complex 34, Cape Canaveral air Force Station","volume":"28","author":"Hood","year":"2008","journal-title":"Groundwater Monitoring Remediation"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"20120322","DOI":"10.1098\/rstb.2012.0322","article-title":"Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases","volume":"368","author":"Hug","year":"2013","journal-title":"Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci."},{"key":"ref23","doi-asserted-by":"publisher","first-page":"134076","DOI":"10.1016\/j.jhazmat.2024.134076","article-title":"Biodegradation of ciprofloxacin using machine learning tools: kinetics and modelling","volume":"470","author":"Kamal","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1080\/01490450490275307","article-title":"Detection and enumeration of sulphate-reducing bacteria in estuarine sediments by competitive PCR","volume":"21","author":"Kondo","year":"2004","journal-title":"Geomicrobiol J."},{"key":"ref25","doi-asserted-by":"publisher","first-page":"fix135","DOI":"10.1093\/femsec\/fix135","article-title":"Comparative genomics of the genus Desulfitobacterium","volume":"93","author":"Kruse","year":"2017","journal-title":"FEMS Microbiol. Ecol."},{"key":"ref26","doi-asserted-by":"publisher","first-page":"5181","DOI":"10.1021\/acs.est.5b05090","article-title":"A data mining approach to predict in situ detoxification potential of chlorinated Ethenes","volume":"50","author":"Lee","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"ref27","doi-asserted-by":"publisher","first-page":"122738","DOI":"10.1016\/j.watres.2024.122738","article-title":"Sulfate-driven microbial collaboration for synergistic remediation of chloroethene-heavy metal pollution","volume":"268","author":"Li","year":"2025","journal-title":"Water Res."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1038\/s43705-021-00025-z","article-title":"Substrate-dependent competition and cooperation relationships between Geobacter and Dehalococcoides for their organohalide respiration","volume":"1","author":"Liang","year":"2021","journal-title":"ISME Commun."},{"key":"ref29","doi-asserted-by":"publisher","first-page":"fiz055","DOI":"10.1093\/femsec\/fiz055","article-title":"Isolation, characterization and bioaugmentation of an acidotolerant 1,2-dichloroethane respiring Desulfitobacterium species from a low pH aquifer","volume":"95","author":"Low","year":"2019","journal-title":"FEMS Microbiol. Ecol."},{"key":"ref30","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1038\/s41579-021-00583-y","article-title":"When anaerobes encounter oxygen: mechanisms of oxygen toxicity, tolerance and defence","volume":"19","author":"Lu","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"ref31","doi-asserted-by":"publisher","first-page":"140788","DOI":"10.1016\/j.jhazmat.2025.140788","article-title":"Ferrous-driven microbial synergy enhances reductive dechlorination under sulfide stress","volume":"501","author":"Lu","year":"2026","journal-title":"J. Hazard. Mater."},{"key":"ref32","doi-asserted-by":"publisher","first-page":"125189","DOI":"10.1016\/j.jhazmat.2021.125189","article-title":"Waste activated sludge stimulates in situ microbial reductive dehalogenation of organohalide-contaminated soil","volume":"411","author":"Lu","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"ref33","doi-asserted-by":"publisher","first-page":"5106","DOI":"10.1021\/es0255711","article-title":"Field demonstration of successful bioaugmentation to achieve dechlorination of tetrachloroethene to ethene","volume":"36","author":"Major","year":"2002","journal-title":"Environ. Sci. Technol."},{"key":"ref34","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/978-3-319-51686-8_9","volume-title":"Microbial Ecology of Extreme Environments","author":"Manefield","year":"2017"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"e03384-16","DOI":"10.1128\/aem.03384-16","article-title":"Effects of sulfate reduction on trichloroethene dechlorination by Dehalococcoides-containing microbial communities","volume":"83","author":"Mao","year":"2017","journal-title":"Appl. Environ. Microbiol."},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2012.00351","article-title":"Ecogenomics of microbial communities in bioremediation of chlorinated contaminated sites","volume":"3","author":"Maphosa","year":"2012","journal-title":"Front. Microbiol."},{"key":"ref37","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1021\/es001285i","article-title":"Reductive Dechlorination of cis-1,2-Dichloroethene and vinyl chloride by \u201cDehalococcoides ethenogenes\u201d","volume":"35","author":"Maym\u00f3-Gatell","year":"2001","journal-title":"Environ. Sci. Technol."},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.1016\/j.envint.2011.06.003","article-title":"Bioremediation approaches for organic pollutants: a critical perspective","volume":"37","author":"Megharaj","year":"2011","journal-title":"Environ. Int."},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.3389\/fenvs.2024.1354422","article-title":"Bioremediation of petroleum hydrocarbon contaminated soil: a review on principles, degradation mechanisms, and advancements","volume":"12","author":"Mekonnen","year":"2024","journal-title":"Front. Environ. Sci."},{"key":"ref40","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s10653-011-9423-1","article-title":"Sulfate reduction in groundwater: characterization and applications for remediation","volume":"34","author":"Miao","year":"2012","journal-title":"Environ. Geochem. Health"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"739","DOI":"10.2217\/fmb.13.32","article-title":"Potential impact of environmental bacteriophages in spreading antibiotic resistance genes","volume":"8","author":"Muniesa","year":"2013","journal-title":"Future Microbiol."},{"key":"ref42","doi-asserted-by":"publisher","first-page":"fix133","DOI":"10.1093\/femsec\/fix133","article-title":"Co-occurrence of genes for aerobic and anaerobic biodegradation of dichloroethane in organochlorine-contaminated groundwater","volume":"93","author":"Munro","year":"2017","journal-title":"FEMS Microbiol. Ecol."},{"key":"ref43","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1186\/s12934-017-0743-4","article-title":"Identification of two organohalide-respiring Dehalococcoidia associated to different dechlorination activities in PCB-impacted marine sediments","volume":"16","author":"Nuzzo","year":"2017","journal-title":"Microb. Cell Factories"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"2223","DOI":"10.3390\/pr12102223","article-title":"In situ and ex situ bioremediation of different persistent soil pollutants as agroecology tool","volume":"12","author":"Perez-Vazquez","year":"2024","journal-title":"PRO"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1007\/s00248-019-01381-z","article-title":"Production of current by Syntrophy between Exoelectrogenic and fermentative Hyperthermophilic microorganisms in heterotrophic biofilm from a Deep-Sea hydrothermal chimney","volume":"79","author":"Pillot","year":"2020","journal-title":"Microb. Ecol."},{"key":"ref46","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/978-3-662-49875-0_14","volume-title":"Organohalide-Respiring Bacteria","author":"Richardson","year":"2016"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"137210","DOI":"10.1016\/j.scitotenv.2020.137210","article-title":"Impact of bacterial motility on biosorption and cometabolism of pyrene in a porous medium","volume":"717","author":"Rolando","year":"2020","journal-title":"Sci. Total Environ."},{"key":"ref48","doi-asserted-by":"publisher","first-page":"1258148","DOI":"10.3389\/fmicb.2023.1258148","article-title":"Bioremediation of contaminated soil and groundwater by in situ biostimulation","volume":"14","author":"Romantschuk","year":"2023","journal-title":"Front. Microbiol."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.chemosphere.2008.03.052","article-title":"Citric acid-modified Fenton\u2019s reaction for the oxidation of chlorinated ethylenes in soil solution systems","volume":"72","author":"Seol","year":"2008","journal-title":"Chemosphere"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/j.mimet.2004.02.003","article-title":"Development of a real-time PCR method for quantification of the three genera Dehalobacter, Dehalococcoides, and Desulfitobacterium in microbial communities","volume":"57","author":"Smits","year":"2004","journal-title":"J. Microbiol. Methods"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"6663","DOI":"10.1128\/AEM.00553-08","article-title":"Phylogenetic comparison of the methanogenic communities from an acidic, oligotrophic fen and an anaerobic digester treating municipal wastewater sludge","volume":"74","author":"Steinberg","year":"2008","journal-title":"Appl. Environ. Microbiol."},{"key":"ref53","doi-asserted-by":"publisher","first-page":"154668","DOI":"10.1016\/j.scitotenv.2022.154668","article-title":"The application of machine learning methods for prediction of metal immobilization remediation by biochar amendment in soil","volume":"829","author":"Sun","year":"2022","journal-title":"Sci. Total Environ."},{"key":"ref54","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.jconhyd.2010.09.001","article-title":"Effectiveness of nanoscale zero-valent iron for treatment of a PCE-DNAPL source zone","volume":"118","author":"Taghavy","year":"2010","journal-title":"J. Contam. Hydrol."},{"key":"ref55","doi-asserted-by":"publisher","first-page":"128969","DOI":"10.1016\/j.jhazmat.2022.128969","article-title":"Effects of co-occurrence of PFASs and chlorinated aliphatic hydrocarbons on microbial communities in groundwater: a field study","volume":"435","author":"Tang","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"ref56","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3389\/fmicb.2016.00100","article-title":"Sister Dehalobacter genomes reveal specialization in Organohalide respiration and recent strain differentiation likely driven by chlorinated substrates","volume":"7","author":"Tang","year":"2016","journal-title":"Front. Microbiol."},{"key":"ref57","doi-asserted-by":"crossref","first-page":"W83","DOI":"10.1093\/nar\/gkae410","article-title":"The galaxy platform for accessible, reproducible, and collaborative data analyses: 2024 update","volume":"52","year":"2024","journal-title":"Nucleic Acids Res."},{"key":"ref58","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1111\/j.1574-6976.2006.00029.x","article-title":"The Desulfitobacterium genus","volume":"30","author":"Villemur","year":"2006","journal-title":"FEMS Microbiol. Rev."},{"key":"ref59","doi-asserted-by":"publisher","first-page":"e00513-23","DOI":"10.1128\/mbio.00513-23","article-title":"Deciphering community interactions of sulfate-reducing microorganisms in complex microbial communities of marine sediments","volume":"14","author":"Wasmund","year":"2023","journal-title":"MBio"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/978-3-662-49875-0_13","volume-title":"Organohalide-Respiring Bacteria","author":"Wei","year":"2016"},{"key":"ref61","volume-title":"Conceptual Site Model - Orica Botany","author":"Woinarski","year":"2022"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"3092","DOI":"10.1111\/1462-2920.13287","article-title":"Isolation and characterization of Dehalobacter sp. strain UNSWDHB capable of chloroform and chlorinated ethane respiration","volume":"18","author":"Wong","year":"2016","journal-title":"Environ. Microbiol."},{"key":"ref63","doi-asserted-by":"publisher","first-page":"17338","DOI":"10.1021\/acs.est.3c05932","article-title":"Improve niche colonization and microbial interactions for Organohalide-respiring-Bacteria-mediated remediation of Chloroethene-contaminated sites","volume":"57","author":"Wu","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"ref64","doi-asserted-by":"publisher","first-page":"133887","DOI":"10.1016\/j.jhazmat.2024.133887","article-title":"Surfactant enhanced persulfate system for the synergistic oxidation and reduction of mixed chlorinated hydrocarbons","volume":"469","author":"Xu","year":"","journal-title":"J. Hazard. Mater."},{"key":"ref65","doi-asserted-by":"publisher","first-page":"121447","DOI":"10.1016\/j.watres.2024.121447","article-title":"Combatting multiple aromatic organohalide pollutants in sediments by bioaugmentation with a single Dehalococcoides","volume":"255","author":"Xu","year":"","journal-title":"Water Res."},{"key":"ref66","doi-asserted-by":"publisher","first-page":"15112","DOI":"10.1021\/acs.est.3c04535","article-title":"Alleviating chlorinated alkane inhibition on Dehalococcoides to achieve detoxification of chlorinated aliphatic Cocontaminants","volume":"57","author":"Xu","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"ref67","doi-asserted-by":"publisher","first-page":"18422","DOI":"10.1007\/s11356-024-32373-3","article-title":"Utility of metagenomics for bioremediation: a comprehensive review on bioremediation mechanisms and microbial dynamics of river ecosystem","volume":"31","author":"Yadav","year":"2024","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"ref68","first-page":"e00757-19","article-title":"Roles of organohalide-respiring Dehalococcoidia in carbon cycling. mSystems","author":"Yang","year":"2020"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1021\/acs.est.8b05871","article-title":"Nitrous oxide is a potent inhibitor of bacterial reductive Dechlorination","volume":"53","author":"Yin","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"ref70","doi-asserted-by":"publisher","first-page":"21212","DOI":"10.1021\/acs.est.3c05667","article-title":"Machine learning modeling based on microbial Community for Prediction of natural attenuation in groundwater","volume":"57","author":"Zhang","year":"2023","journal-title":"Environ. Sci. Technol."}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2026.1845514\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:31:36Z","timestamp":1789623096000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2026.1845514\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,17]]},"references-count":68,"alternative-id":["10.3389\/fmicb.2026.1845514"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2026.1845514","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,17]]},"article-number":"1845514"}}