{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T06:03:49Z","timestamp":1781071429586,"version":"3.54.1"},"reference-count":134,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>\n                    Ticks are important vector arthropods, which can carry and transmit a variety of pathogenic microorganisms, and pose a serious threat to global public health. This study reviews the research progress of the main and emerging tick-borne pathogens, such as Lyme disease related\n                    <jats:italic>Borrelia, Rickettsia, Babesia<\/jats:italic>\n                    , Thrombocytopenia Syndrome Virus (SFTSV), Tick-borne Encephalitis Virus (TBEV), Alongshan virus (ALSV), etc., focuses on their genomic diversity, pathogenicity, transmission and immune escape, co- infection. In addition, the application of new detection technology [Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), metagenomic next-generation sequencing (mNGS), microfluidics] in Tick-Borne pathogens is summarized.It highlights current research limitations, including delayed vaccine development and inadequate surveillance systems. Finally, future research directions are prospected, providing theoretical references for the prevention and control of tick-borne diseases.\n                  <\/jats:p>","DOI":"10.3389\/fmicb.2026.1866307","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T05:39:26Z","timestamp":1781069966000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Research progress on emerging and important Tick-Borne pathogens"],"prefix":"10.3389","volume":"17","author":[{"given":"Gang","family":"Duan","sequence":"first","affiliation":[{"name":"Chongqing Key Laboratory of Highly Pathogenic Microbes, Chongqing Research Center for Disease Prevention and Public Health, Chongqing Center for Disease Control and Prevention, Chongqing Academy of Preventive Medicine","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linghan","family":"Kong","sequence":"additional","affiliation":[{"name":"Chongqing Wanzhou District Center for Disease Control and Prevention","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sicheng","family":"Duan","sequence":"additional","affiliation":[{"name":"College of Humanities and Sciences, National University of Singapore","place":["Singapore, Singapore"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujun","family":"Nie","sequence":"additional","affiliation":[{"name":"Chongqing Key Laboratory of Highly Pathogenic Microbes, Chongqing Research Center for Disease Prevention and Public Health, Chongqing Center for Disease Control and Prevention, Chongqing Academy of Preventive Medicine","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanjiang","family":"Gu","sequence":"additional","affiliation":[{"name":"Chongqing Key Laboratory of Highly Pathogenic Microbes, Chongqing Research Center for Disease Prevention and Public Health, Chongqing Center for Disease Control and Prevention, Chongqing Academy of Preventive Medicine","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1016\/j.ttbdis.2019.04.018","article-title":"Presence of Rickettsia aeschlimannii, \u2018Candidatus Rickettsia Barbariae' and coxiella burnetii in ticks from livestock in Northwestern Algeria","volume":"10","author":"Abdelkadir","year":"2019","journal-title":"Ticks Tick Borne Dis"},{"key":"B2","doi-asserted-by":"publisher","first-page":"e0174924","DOI":"10.1128\/mbio.01749-24","article-title":"Natural selection and recombination at host-interacting lipoprotein loci drive genome diversification of lyme disease and related bacteria","volume":"15","author":"Akther","year":"2024","journal-title":"MBio"},{"key":"B3","doi-asserted-by":"publisher","first-page":"946631","DOI":"10.3389\/fmicb.2022.946631","article-title":"Metagenomic profiles of dermacentor tick pathogens from across mongolia, using next generation sequencing","volume":"13","author":"Altantogtokh","year":"2022","journal-title":"Front. 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