{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T05:19:00Z","timestamp":1787894340426,"version":"build-2784847793"},"reference-count":67,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Salmonella<\/jats:italic>\n                      1,4,[5],12:i:- ST34 has emerged as a significant public health issue due to its association with various antimicrobial resistance genes (ARGs) and transferable plasmids. However, its genomic characteristics and potential influence on public health in Guizhou have not been comprehensively assessed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      From 2019 to 2023, a 5-year surveillance was conducted in nine cities (prefectures) of Guizhou Province. We integrated phenotypic and genomic analyses of 281 clinical\n                      <jats:italic>Salmonella<\/jats:italic>\n                      1,4,[5],12:i:- ST34 isolates to investigate the prevalence of ARGs and plasmids and to analyze the molecular epidemiology and evolution.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The isolates exhibited resistance to first-line antibiotics, with 22.4% for ciprofloxacin, 11.4% for azithromycin, 18.5% for ceftazidime, and 39.1% for cefotaxime. ARGs showed substantial agreement with phenotypes for tetracycline, macrolides, third-generation cephalosporins (3GCs), carbapenems, and colistin (80.8\u2013100.0% consistency;\n                      <jats:italic>Kappa<\/jats:italic>\n                      : 0.50\u20131.00). Plasmid analysis identified IncQ1 (84.3%) and IncHI2\/IncHI2A (26.3%) as the main replicons, with the variety of plasmid replicons increasing from 7 to 21 over the 5 years. ARGs associated with resistance to critically important antibiotics (CIAs) were frequently predicted to be located on plasmid-associated contigs, with significant associations observed between IncHI2\/IncHI2A plasmids and ARGs conferring resistance to fluoroquinolones, macrolides, and cephalosporins (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.05). Molecular typing divided 281 isolates into 37 cgSTs, with cgST52428 being the most common. Molecular epidemiological analysis revealed that Guizhou isolates primarily clustered together, sharing close genetic ties with those from Sichuan and Guangdong, and exhibited the highest genetic similarity to pork-derived isolates. Phylogenetic analysis revealed clustering of CIA-resistant ARGs and plasmids in Clades 4 and 5, with a significant association between IncHI2\/IncHI2A plasmids and CIA-resistant ARGs (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      = 112.12,\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.001). Additionally, class 1 integron was associated with higher ARG burdens, while virulence-associated genes were conserved and predominantly chromosome-associated. Gene-content analysis revealed that isolates in Clades 4 and 5 harbored the largest mean gene complements, and cgST52428 isolates also harbored the largest among dominant cgSTs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>\n                      This study presents a comprehensive genomic profile of\n                      <jats:italic>Salmonella<\/jats:italic>\n                      1,4,[5],12:i:- ST34 in Guizhou, providing essential data for exploring the resistance characteristics and investigating the molecular epidemiology of\n                      <jats:italic>Salmonella<\/jats:italic>\n                      1,4,[5],12:i:-.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmicb.2026.1875505","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T04:35:07Z","timestamp":1787891707000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Genomic surveillance reveals escalating antimicrobial resistance and plasmid diversity in clinical Salmonella 1,4,[5],12:i:- ST34 isolates from Guizhou Province, China"],"prefix":"10.3389","volume":"17","author":[{"given":"Ge","family":"Zhu","sequence":"first","affiliation":[{"name":"The Key Laboratory of Environmental Pollution Monitoring and Disease Control, School of Public Health, Ministry of Education, Guizhou Medical University","place":["Guiyang, Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lv","family":"You","sequence":"additional","affiliation":[{"name":"Laboratory of Bacterial Disease, Experimental Center, Guizhou Provincial Center for Disease Control and Prevention","place":["Guiyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deyu","family":"Li","sequence":"additional","affiliation":[{"name":"Laboratory of Bacterial Disease, Experimental Center, Guizhou Provincial Center for Disease Control and Prevention","place":["Guiyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhua","family":"Wang","sequence":"additional","affiliation":[{"name":"The Key Laboratory of Environmental Pollution Monitoring and Disease Control, School of Public Health, Ministry of Education, Guizhou Medical University","place":["Guiyang, Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shijun","family":"Li","sequence":"additional","affiliation":[{"name":"Laboratory of Bacterial Disease, Experimental Center, Guizhou Provincial Center for Disease Control and Prevention","place":["Guiyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Liu","sequence":"additional","affiliation":[{"name":"Preparatory College, Guizhou Provincial Center for Disease Control and Prevention","place":["Guiyang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Wei","sequence":"additional","affiliation":[{"name":"Experimental Center, Guizhou Provincial Center for Disease Control and Prevention","place":["Guiyang, China"]},{"name":"School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Guizhou Medical University","place":["Guizhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"e0278321","DOI":"10.1371\/journal.pone.0278321","article-title":"The CRISPR genotypes and genetic diversity of different serogroups of nontyphoidal Salmonella in Guizhou Province, 2013\u20132018","volume":"17","author":"Bai","year":"2022","journal-title":"PLoS ONE"},{"key":"B2","doi-asserted-by":"publisher","first-page":"e02357","DOI":"10.1128\/AAC.02357-17","article-title":"PSTM6-275, a conjugative IncHI2 plasmid of Salmonella enterica that confers antibiotic and heavy-metal resistance under changing physiological conditions","volume":"62","author":"Billman-Jacobe","year":"2018","journal-title":"Antimicrob. Agents. Chemother"},{"key":"B3","doi-asserted-by":"publisher","first-page":"mgen000798","DOI":"10.1099\/mgen.0.000798","article-title":"Mobility of antimicrobial resistance across serovars and disease presentations in non-typhoidal Salmonella from animals and humans in Vietnam","volume":"8","author":"Bloomfield","year":"2022","journal-title":"Microb. Genom"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1017\/S095026881700036X","article-title":"Salmonella in the pork production chain and its impact on human health in the European Union","volume":"145","author":"Bonardi","year":"2017","journal-title":"Epidemiol. Infect"},{"key":"B5","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.tim.2020.05.011","article-title":"The role of integrative and conjugative elements in antibiotic resistance evolution","volume":"29","author":"Botelho","year":"2021","journal-title":"Trends Microbiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1038\/s41579-023-00926-x","article-title":"Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era","volume":"22","author":"Castaneda-Barba","year":"2024","journal-title":"Nat. Rev. Microbiol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.3389\/fmicb.2016.01566","article-title":"IncHI2 plasmids are predominant in antibiotic-resistant Salmonella isolates","volume":"7","author":"Chen","year":"2016","journal-title":"Front. Microbiol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1038\/s42003-023-05365-1","article-title":"Multidrug resistance plasmids underlie clonal expansions and international spread of Salmonella enterica serotype 1,4,[5],12:i:- ST34 in southeast Asia","volume":"6","author":"Chung The","year":"2023","journal-title":"Commun. Biol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"e0236436","DOI":"10.1371\/journal.pone.0236436","article-title":"Distribution of heavy metal resistance elements in Canadian Salmonella 4,[5],12:i:- populations and association with the monophasic genotypes and phenotype","volume":"15","author":"Clark","year":"2020","journal-title":"PLoS ONE"},{"key":"B10","year":"2023","journal-title":"Performance Standards for Antimicrobial Susceptibility Testing. CLSI Supplement M100"},{"key":"B11","doi-asserted-by":"publisher","first-page":"3517","DOI":"10.1038\/s41467-023-38902-x","article-title":"A global genomic analysis of Salmonella concord reveals lineages with high antimicrobial resistance in Ethiopia","volume":"14","author":"Cuypers","year":"2023","journal-title":"Nat. Commun"},{"key":"B12","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3390\/pathogens11020147","article-title":"Role of efflux pump-mediated antibiotic resistance in quorum sensing-regulated biofilm formation by Salmonella Typhimurium","volume":"11","author":"Dawan","year":"2022","journal-title":"Pathogens"},{"key":"B13","doi-asserted-by":"publisher","first-page":"705230","DOI":"10.3389\/fmicb.2021.705230","article-title":"Emergence of IncHI2 plasmids with mobilized colistin resistance mcr-9 gene in ESBL-producing, multidrug-resistant Salmonella Typhimurium and its monophasic variant ST34 from food-producing animals in Italy","volume":"12","author":"Diaconu","year":"2021","journal-title":"Front. Microbiol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1093\/cid\/cix909","article-title":"Salmonella enterica serotype 4,[5],12:i:- in swine in the United States Midwest: an emerging multidrug-resistant clade","volume":"66","author":"Elnekave","year":"2018","journal-title":"Clin. Infect. Dis"},{"key":"B15","doi-asserted-by":"publisher","first-page":"e8442","DOI":"10.2903\/j.efsa.2023.8442","article-title":"The European Union one health 2022 zoonoses report","volume":"21","year":"2023","journal-title":"EFSA J"},{"key":"B16","doi-asserted-by":"publisher","first-page":"e5598","DOI":"10.2903\/j.efsa.2019.5598","article-title":"The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2017","volume":"17","year":"2019","journal-title":"EFSA J"},{"key":"B17","doi-asserted-by":"publisher","first-page":"e5500","DOI":"10.2903\/j.efsa.2018.5500","article-title":"The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017","volume":"16","year":"2018","journal-title":"EFSA J"},{"key":"B18","doi-asserted-by":"publisher","first-page":"e00591","DOI":"10.1128\/AEM.00591-19","article-title":"Worldwide epidemiology of Salmonella serovars in animal-based foods: a meta-analysis","volume":"85","author":"Ferrari","year":"2019","journal-title":"Appl. Environ. Microbiol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"680","DOI":"10.3389\/fmicb.2016.00680","article-title":"Horizontal acquisition of a multidrug-resistance module (R-type ASSuT) is responsible for the monophasic phenotype in a widespread clone of Salmonella serovar 4,[5],12:i","volume":"7","author":"Garcia","year":"2016","journal-title":"Front. Microbiol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"e0033221","DOI":"10.1128\/Spectrum.00332-21","article-title":"Epidemiological analysis of Salmonella enterica subsp. Enterica serovar Dublin in German cattle herds using whole-genome sequencing","volume":"9","author":"Garcia-Soto","year":"2021","journal-title":"Microbiol. Spectr"},{"key":"B21","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.3390\/microorganisms13122729","article-title":"Genomic insights into antimicrobial resistance and virulence of monophasic Salmonella enterica I 4,[5],12:i:- isolates from clinical and environmental sources in Jeollanam-do, Korea","volume":"13","author":"Go","year":"2025","journal-title":"Microorganisms"},{"key":"B22","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.resmic.2009.10.002","article-title":"Supplement 2003-2007 (no. 47) to the white-kauffmann-le minor scheme","volume":"161","author":"Guibourdenche","year":"2010","journal-title":"Res. Microbiol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"823684","DOI":"10.3389\/fcimb.2022.823684","article-title":"Global threat of carbapenem-resistant gram-negative bacteria","volume":"12","author":"Jean","year":"2022","journal-title":"Front. Cell. Infect. Microbiol"},{"key":"B24","doi-asserted-by":"publisher","first-page":"100940","DOI":"10.1016\/j.lanmic.2024.07.003","article-title":"WHO publishes updated list of bacterial priority pathogens","volume":"5","author":"Jesudason","year":"2024","journal-title":"Lancet Microbe."},{"key":"B25","doi-asserted-by":"publisher","first-page":"2200314","DOI":"10.2807\/1560-7917.ES.2022.27.15.2200314","article-title":"Investigation of an international outbreak of multidrug-resistant monophasic Salmonella Typhimurium associated with chocolate products, EU\/EEA and United Kingdom, February to April 2022","volume":"27","author":"Larkin","year":"2022","journal-title":"Eurosurveillance"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1016\/j.gpb.2022.02.005","article-title":"Genomic epidemiology of carbapenemase-producing klebsiella pneumoniae in China","volume":"20","author":"Li","year":"2022","journal-title":"Genom. Proteomics Bioinformatics"},{"key":"B27","doi-asserted-by":"publisher","first-page":"111129","DOI":"10.1016\/j.ijfoodmicro.2025.111129","article-title":"The genomic characteristics of dominant Salmonella enterica serovars from retail pork in Sichuan Province, China","volume":"434","author":"Li","year":"2025","journal-title":"Int. J. Food Microbiol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1912","DOI":"10.3390\/microorganisms12091912","article-title":"Sequence types and antimicrobial resistance profiles of Salmonella Typhimurium in the food chain in Singapore","volume":"12","author":"Lim","year":"2024","journal-title":"Microorganisms"},{"key":"B29","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.tim.2023.10.006","article-title":"Plasmid-mediated colistin-resistance genes: mcr","volume":"32","author":"Liu","year":"2024","journal-title":"Trends Microbiol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S1473-3099(15)00424-7","article-title":"Emergence of plasmid-mediated colistin resistance mechanism mcr-1 in animals and human beings in China: a microbiological and molecular biological study","volume":"16","author":"Liu","year":"2016","journal-title":"Lancet Infect. Dis"},{"key":"B31","doi-asserted-by":"publisher","first-page":"e0266443","DOI":"10.1371\/journal.pone.0266443","article-title":"Highly prevalent MDR, frequently carrying virulence genes and antimicrobial resistance genes in Salmonella enterica serovar 4,[5],12:i:- isolates from Guizhou Province, China","volume":"17","author":"Long","year":"2022","journal-title":"PLoS ONE"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1166615","DOI":"10.3389\/fmicb.2023.1166615","article-title":"Pathogen genomics and phage-based solutions for accurately identifying and controlling Salmonella pathogens","volume":"14","author":"Lopez-Garcia","year":"2023","journal-title":"Front. Microbiol"},{"key":"B33","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin. Microbiol. Infect"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6711a3","article-title":"Preliminary incidence and trends of infections with pathogens transmitted commonly through food-foodborne diseases active surveillance network, 10 United States Sites, 2006\u20132017","author":"Marder Mph","year":"2018","journal-title":"MMWR. Morb. Mortal. Wkly Rep"},{"key":"B35","doi-asserted-by":"publisher","first-page":"127631","DOI":"10.1016\/j.micres.2024.127631","article-title":"Epidemiology and antimicrobial resistance of Salmonella serovars Typhimurium and 4,[5],12:i- recovered from hospitalized patients in China","volume":"282","author":"Nambiar","year":"2024","journal-title":"Microbiol. Res"},{"key":"B36","doi-asserted-by":"publisher","first-page":"189","DOI":"10.3390\/antibiotics14020189","volume":"14","author":"Peruzy","year":"2025"},{"key":"B37","doi-asserted-by":"publisher","first-page":"1158588","DOI":"10.3389\/fvets.2023.1158588","article-title":"An overview of carbapenem-resistant organisms from food-producing animals, seafood, aquaculture, companion animals, and wildlife","volume":"10","author":"Ramirez-Castillo","year":"2023","journal-title":"Front. Vet. Sci"},{"key":"B38","doi-asserted-by":"publisher","first-page":"1565631","DOI":"10.3389\/fmicb.2025.1565631","article-title":"Genomic characteristics and antibiotic resistance profiles of monophasic Salmonella Typhimurium in Shaanxi Province, China","volume":"16","author":"Shi","year":"2025","journal-title":"Front. Microbiol"},{"key":"B39","doi-asserted-by":"publisher","first-page":"105326","DOI":"10.1016\/j.ebiom.2024.105326","article-title":"Decoding the origins, spread, and global risks of mcr-9 gene","volume":"108","author":"Song","year":"2024","journal-title":"EBioMedicine"},{"key":"B40","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1089\/fpd.2019.2676","article-title":"The epidemiology of monophasic Salmonella Typhimurium","volume":"17","author":"Sun","year":"2020","journal-title":"Foodborne Pathog. Dis"},{"key":"B41","doi-asserted-by":"publisher","first-page":"e0116423","DOI":"10.1128\/msystems.01164-23","article-title":"Antimicrobial resistance and population genomics of emerging multidrug-resistant Salmonella 4,[5],12:i:- in Guangdong, China","volume":"9","author":"Sun","year":"2024","journal-title":"Msystems"},{"key":"B42","doi-asserted-by":"publisher","first-page":"e621","DOI":"10.1371\/journal.pntd.0000621","article-title":"Identification by PCR of non-typhoidal Salmonella enterica serovars associated with invasive infections among febrile patients in Mali","volume":"4","author":"Tennant","year":"2010","journal-title":"Plos Neglect. Trop. Dis"},{"key":"B43","doi-asserted-by":"publisher","first-page":"bbae322","DOI":"10.1093\/bib\/bbae322","article-title":"PlasmidHunter: accurate and fast prediction of plasmid sequences using gene content profile and machine learning","volume":"25","author":"Tian","year":"2024","journal-title":"Brief. Bioinform"},{"key":"B44","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1080\/14787210.2026.2683605","article-title":"Inhibiting horizontal gene transfer to contain antimicrobial resistance: conjugation and plasmid maintenance as druggable targets","volume":"24","author":"Touati","year":"2026","journal-title":"Expert Rev. Anti Infect. Ther."},{"key":"B45","doi-asserted-by":"publisher","first-page":"4280","DOI":"10.1038\/s41467-019-11844-z","article-title":"An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation","volume":"10","author":"Van Puyvelde","year":"2019","journal-title":"Nat. Commun"},{"key":"B46","doi-asserted-by":"publisher","first-page":"106051","DOI":"10.1016\/j.micpath.2023.106051","article-title":"Molecular characterization of class 1 integrons in carbapenem-resistant Enterobacterales isolates","volume":"177","author":"Wang","year":"2023","journal-title":"Microb. Pathog"},{"key":"B47","doi-asserted-by":"publisher","first-page":"nwac269","DOI":"10.1093\/nsr\/nwac269","article-title":"The temporal dynamics of antimicrobial-resistant Salmonella enterica and predominant serovars in China","volume":"10","author":"Wang","year":"2023","journal-title":"Natl. Sci. Rev"},{"key":"B48","doi-asserted-by":"publisher","first-page":"4254","DOI":"10.1038\/s41467-022-31908-x","article-title":"Development of a novel core genome MLST scheme for tracing multidrug resistant staphylococcus capitis","volume":"13","author":"Wang","year":"2022","journal-title":"Nat. Commun"},{"key":"B49","doi-asserted-by":"publisher","first-page":"113227","DOI":"10.1016\/j.celrep.2023.113227","article-title":"Microevolution of Salmonella 4,[5],12:i:- derived from Salmonella enterica serovar Typhimurium through complicated transpositions","volume":"42","author":"Wang","year":"","journal-title":"Cell Rep"},{"key":"B50","doi-asserted-by":"publisher","first-page":"e0094423","DOI":"10.1128\/aem.00944-23","article-title":"Poultry production as the main reservoir of ciprofloxacin- and tigecycline-resistant extended-spectrum beta-lactamase (ESBL)-producing Salmonella enterica serovar kentucky ST198.2-2 causing human infections in China","volume":"89","author":"Wang","year":"","journal-title":"Appl. Environ. Microbiol"},{"key":"B51","doi-asserted-by":"publisher","first-page":"127441","DOI":"10.1016\/j.micres.2023.127441","article-title":"Prevalence and molecular characterization of mcr-1-positive foodborne ST34-Salmonella isolates in China","volume":"274","author":"Wang","year":"","journal-title":"Microbiol. Res"},{"key":"B52","doi-asserted-by":"publisher","first-page":"e0282254","DOI":"10.1371\/journal.pone.0282254","article-title":"Serotype distribution, trend of multidrug resistance and prevalence of beta-lactamase resistance genes in human Salmonella isolates from clinical specimens in Guizhou, China","volume":"18","author":"Wei","year":"2023","journal-title":"PLoS ONE"},{"key":"B53","doi-asserted-by":"publisher","first-page":"e0008796","DOI":"10.1371\/journal.pntd.0008796","article-title":"Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets","volume":"14","author":"Wilson","year":"2020","journal-title":"Plos Neglect. Trop. Dis"},{"key":"B54","volume-title":"WHO List of Medically Important Antimicrobials: a Risk Management Tool for Mitigating Antimicrobial Resistance Due to Non-Human Use (7th Revision)","year":"2024"},{"key":"B55","doi-asserted-by":"publisher","first-page":"704636","DOI":"10.3389\/fmicb.2021.704636","article-title":"Genomic investigation of Salmonella isolates recovered from a pig slaughtering process in Hangzhou, China","volume":"12","author":"Wu","year":"2021","journal-title":"Front. Microbiol"},{"key":"B56","doi-asserted-by":"publisher","first-page":"1498995","DOI":"10.3389\/fmicb.2025.1498995","article-title":"Genome analysis of colistin-resistant Salmonella isolates from human sources in Guizhou of southwestern China, 2019\u20132023","volume":"16","author":"Wu","year":"2025","journal-title":"Front. Microbiol"},{"key":"B57","doi-asserted-by":"publisher","first-page":"1490183","DOI":"10.3389\/fcimb.2025.1490183","article-title":"Genomic epidemiology and public health implications of zoonotic monophasic Salmonella Typhimurium ST34","volume":"15","author":"Wu","year":"2025","journal-title":"Front. Cell. Infect. Microbiol"},{"key":"B58","doi-asserted-by":"publisher","first-page":"100953","DOI":"10.1016\/j.drup.2023.100953","article-title":"Global population structure and genomic surveillance framework of carbapenem-resistant Salmonella enterica","volume":"68","author":"Wu","year":"2023","journal-title":"Drug Resist. Update"},{"key":"B59","doi-asserted-by":"publisher","first-page":"433","DOI":"10.3969\/j.issn.1002-2694.2022.05.007","article-title":"Genomic characterization of human-derived Salmonella in Chengdu","volume":"38","author":"Xiao","year":"2022","journal-title":"Chin. J. Zoonoses"},{"key":"B60","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1080\/22221751.2022.2058420","article-title":"Identification and genetic characterization of two conjugative plasmids that confer azithromycin resistance in Salmonella","volume":"11","author":"Xie","year":"2022","journal-title":"Emerg. Microbes Infect"},{"key":"B61","doi-asserted-by":"publisher","first-page":"456","DOI":"10.3390\/antibiotics13050456","article-title":"Dissemination of ceftriaxone-resistant Salmonella Enteritidis harboring plasmids encoding blaCTX\u2212M\u221255 or blaCTX\u2212M\u221214 gene in China","volume":"13","author":"Yang","year":"2024","journal-title":"Antibiotics"},{"key":"B62","doi-asserted-by":"publisher","first-page":"e0048023","DOI":"10.1128\/msphere.00480-23","article-title":"Molecular characterization of IncFII plasmid carrying blaNDM\u22125 in a Salmonella enterica serovar Typhimurium ST34 clinical isolate in China","volume":"8","author":"Zeng","year":"2023","journal-title":"Msphere"},{"key":"B63","doi-asserted-by":"publisher","first-page":"109993","DOI":"10.1016\/j.vetmic.2024.109993","article-title":"Prevalence and genetic characteristics of Salmonella enterica serovar Meleagridis from animals and humans","volume":"290","author":"Zhang","year":"2024","journal-title":"Vet. Microbiol"},{"key":"B64","doi-asserted-by":"publisher","first-page":"110572","DOI":"10.1016\/j.ijfoodmicro.2024.110572","article-title":"Diversity of evolution in MDR monophasic S. Typhimurium among food animals and food products in Southern China from 2011 to 2018","volume":"412","author":"Zhao","year":"2024","journal-title":"Int. J. Food Microbiol"},{"key":"B65","first-page":"1037","article-title":"Antimicrobial resistance characteristics and genomic analysis of Salmonella Typhimurium and its monophasic variant in Hangzhou","volume":"44","author":"Zheng","year":"2024","journal-title":"China. J. Microbiol. Immunol"},{"key":"B66","doi-asserted-by":"publisher","first-page":"1200088","DOI":"10.3389\/fmicb.2023.1200088","article-title":"Prevalence and genetic diversity of multidrug-resistant Salmonella Typhimurium monophasic variant in a swine farm from China","volume":"14","author":"Zhou","year":"2023","journal-title":"Front. Microbiol"},{"key":"B67","doi-asserted-by":"publisher","first-page":"1515576","DOI":"10.3389\/fmicb.2025.1515576","article-title":"Comparative genomic and antimicrobial resistance profiles of Salmonella strains isolated from pork and human sources in Sichuan, China","volume":"16","author":"Zuo","year":"2025","journal-title":"Front. Microbiol"}],"container-title":["Frontiers in Microbiology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2026.1875505\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T04:35:12Z","timestamp":1787891712000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2026.1875505\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,28]]},"references-count":67,"alternative-id":["10.3389\/fmicb.2026.1875505"],"URL":"https:\/\/doi.org\/10.3389\/fmicb.2026.1875505","relation":{},"ISSN":["1664-302X"],"issn-type":[{"value":"1664-302X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,28]]},"article-number":"1875505"}}