{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:13:36Z","timestamp":1790241216127,"version":"4.1.0"},"reference-count":56,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Microbiol."],"abstract":"<jats:p>\n                    Global livestock industry is confronted with severe feed-supply pressure, and valorizing agro-industrial by-products has become a promising way to alleviate feed resource shortages. Large quantities of pineapple waste are produced annually during pineapple processing, but antinutritional factors greatly limit its direct application in pig diets. Pineapple waste (PW) is a promising agro-industrial by-product for feed production; however, its high levels of antinutritional factors and structural carbohydrates limit its utilization in monogastric animals. This study aimed to develop a synthetic microbial community (SysComs) for upgrading PW into a functional feed ingredient. Four functional strains were separately screened according to their dominant single degrading or metabolite-synthesizing traits, and further combined into a synthetic community owing to their complementary metabolic capacities, including tannin-degrading\n                    <jats:italic>Lactiplantibacillus plantarum<\/jats:italic>\n                    , xylan-degrading\n                    <jats:italic>Pediococcus pentosaceus<\/jats:italic>\n                    , phytase-producing\n                    <jats:italic>Lactobacillus fermentum<\/jats:italic>\n                    , and butyrate-producing\n                    <jats:italic>Clostridium butyricum<\/jats:italic>\n                    . Fermentation with SysComs markedly improved the nutritional and functional properties of PW. Compared with raw PW, fermented pineapple waste (FPW) showed substantial reductions in tannin and phytate contents, with removal rates reaching 80.65 and 89.62%, respectively. Total dietary fiber and insoluble dietary fiber were significantly decreased, whereas soluble dietary fiber increased from 5.60 to 8.18%. Meanwhile, butyrate concentration increased from 1.65 to 6.63%, accompanied by a decrease in pH from 6.10 to 4.87. Microbial community analysis showed that SysComs fermentation shifted PW from a contaminant-rich microbial community toward a lactic acid bacteria-dominated structure, with enrichment of\n                    <jats:italic>Lactobacillus<\/jats:italic>\n                    ,\n                    <jats:italic>Levilactobacillus<\/jats:italic>\n                    ,\n                    <jats:italic>Enterococcus<\/jats:italic>\n                    ,\n                    <jats:italic>Bacillus<\/jats:italic>\n                    , and\n                    <jats:italic>Weissella<\/jats:italic>\n                    . Untargeted metabolomics further revealed that fermentation extensively remodeled the metabolite profile of PW, with 258 metabolites upregulated and 437 downregulated. Pathways related to flavonoid biosynthesis, flavone and flavonol biosynthesis, and secondary metabolite biosynthesis were significantly enriched. Luteolin, taxifolin, phlorizin, and gallocatechin were markedly increased. In pig experiment, dietary FPW supplementation significantly increased average daily gain by 13.10% and improved gross energy digestibility from 85.36 to 87.46% compared with the control group (\n                    <jats:italic>p<\/jats:italic>\n                    \u202f&amp;lt;\u202f0.05). Moreover, FPW reshaped the colonic microbiota by increasing microbial richness and enriching beneficial fiber-degrading and short-chain fatty acid-associated taxa, including\n                    <jats:italic>Christensenellaceae<\/jats:italic>\n                    R-7 group,\n                    <jats:italic>Lachnospiraceae<\/jats:italic>\n                    NK4A136 group, and\n                    <jats:italic>Monoglobus<\/jats:italic>\n                    . These findings demonstrate that SysComs fermentation effectively reduced antinutritional factors, enhanced nutrient accessibility, enriched functional metabolites, and improved growth performance and gut microbial ecology in pigs. Targeted microbial fermentation is an effective strategy for converting pineapple waste into a high-value functional feed ingredient.\n                  <\/jats:p>","DOI":"10.3389\/fmicb.2026.1929714","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:51:37Z","timestamp":1790239897000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Synthetic microbial community to enhance the fermentation and feed valorization of pineapple waste"],"prefix":"10.3389","volume":"17","author":[{"given":"Kuanmin","family":"Yang","sequence":"first","affiliation":[{"name":"Shenzhen Kingkey Smart Agriculture Times Co., Ltd.","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju","family":"Qin","sequence":"additional","affiliation":[{"name":"Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry 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Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture, Guangdong Public Laboratory of Animal Breeding and Nutrition, Guangdong Engineering Technology Research Center of Animal Meat Quality and Safety Control and Evaluation","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Yu","sequence":"additional","affiliation":[{"name":"Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture, Guangdong Public Laboratory of Animal Breeding and Nutrition, Guangdong Engineering Technology Research Center of Animal Meat Quality and Safety Control and Evaluation","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhichang","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture, Guangdong Public Laboratory of Animal Breeding and Nutrition, Guangdong Engineering Technology Research Center of Animal Meat Quality and Safety Control and Evaluation","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Rong","sequence":"additional","affiliation":[{"name":"Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture, Guangdong Public Laboratory of Animal Breeding and Nutrition, 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Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture, Guangdong Public Laboratory of Animal Breeding and Nutrition, Guangdong Engineering Technology Research Center of Animal Meat Quality and Safety Control and Evaluation","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dun","family":"Deng","sequence":"additional","affiliation":[{"name":"Shenzhen Kingkey Smart Agriculture Times Co., Ltd.","place":["Shenzhen, China"]},{"name":"Institute of Animal Science, Guangdong Academy of Agricultural Sciences, State Key Laboratory of Swine and Poultry Breeding Industry, Key Laboratory of Animal Nutrition and Feed Science in South China, Ministry of Agriculture, Guangdong Public Laboratory of Animal Breeding and Nutrition, Guangdong Engineering Technology Research Center of Animal Meat Quality and Safety Control and 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Anim. Sci."},{"key":"ref21","doi-asserted-by":"publisher","first-page":"e13535","DOI":"10.1111\/asj.135355","article-title":"Digestive, fermentative, and physical properties of pineapple residue as a feed for cattle","volume":"92","author":"Liu","year":"2021","journal-title":"Anim. Sci. J. Nihon chikusan Gakkaiho"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"841762","DOI":"10.3389\/fvets.2022.841762","article-title":"Effects of fermented feed on the growth performance, intestinal function, and microbiota of piglets weaned at different age","volume":"9","author":"Liu","year":"2022","journal-title":"Front. Vet. Sci."},{"key":"ref23","doi-asserted-by":"publisher","first-page":"101465","DOI":"10.1016\/j.fochx.2024.101465","article-title":"Probiotic Bacillus as fermentation agents: status, potential insights, and future perspectives","author":"Liu","year":"2024","journal-title":"Food Chem."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"79","DOI":"10.3390\/fermentation9020079","article-title":"The metabolite profiling and microbial community dynamics during pineapple by-product fermentation using co-inoculation of lactic acid bacteria and yeast","volume":"9","author":"Luo","year":"2023","journal-title":"Fermentation"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"e160","DOI":"10.1002\/imt2.160","article-title":"Clostridium butyricumand carbohydrate active enzymes contribute to the reduced fat deposition in pigs","volume":"3","author":"Ma","year":"2024","journal-title":"iMeta"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1744","DOI":"10.1017\/S175173111700324X","article-title":"Review: feed demand landscape and implications of food-not feed strategy for food security and climate change","volume":"12","author":"Makkar","year":"2018","journal-title":"Animal"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"824","DOI":"10.5740\/jaoacint.cs2011_25","article-title":"Determination of insoluble, soluble, and total dietary fiber (CODEX definition) by enzymatic-gravimetric method and liquid chromatography: collaborative study","volume":"95","author":"McCleary","year":"2012","journal-title":"J. AOAC Int."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/s13568-019-0786-5","article-title":"A metabolomic approach to understand the solid-state fermentation of okara using Bacillus subtilis WX-17 for enhanced nutritional profile","volume":"9","author":"Mok","year":"2019","journal-title":"AMB Express"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"110555","DOI":"10.1016\/j.ijfoodmicro.2023.110555","article-title":"Food phenolics and Lactiplantibacillus plantarum","volume":"412","author":"Mu\u00f1oz","year":"2024","journal-title":"Int. J. Food Microbiol."},{"key":"ref30","year":""},{"key":"ref31","year":""},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfutfo.2025.06.022","article-title":"Anti-nutrients of plant-based food: physicochemical properties, effects on health and degradation techniques\u2014a comprehensive review","author":"Okaiyeto","year":"2025","journal-title":"J. Future Foods"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.3390\/foods14091451","article-title":"\u0392-Glucosidase activity of Lactiplantibacillus plantarum: a key player in food fermentation and human health","volume":"14","author":"Paventi","year":"2025","journal-title":"Foods"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"109854","DOI":"10.1016\/j.foodres.2020.109854","article-title":"Fruits and fruit by-products as sources of bioactive compounds. Benefits and trends of lactic acid fermentation in the development of novel fruit-based functional beverages","volume":"140","author":"Ruiz Rodr\u00edguez","year":"2021","journal-title":"Food Res. Int."},{"key":"ref35","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s43014-020-0020-5","article-title":"Plant food anti-nutritional factors and their reduction strategies: an overview","volume":"2","author":"Samtiya","year":"2020","journal-title":"Food Prod. Process. Nutr."},{"key":"ref36","doi-asserted-by":"publisher","first-page":"e0104923","DOI":"10.1128\/msystems.01049-23","article-title":"Interrelation between gut microbiota, SCFA, and fatty acid composition in pigs","volume":"9","author":"Sebasti\u00e0","year":"2024","journal-title":"mSystems"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"1103836","DOI":"10.3389\/fmicb.2022.1103836","article-title":"Butyrate producers, \u201cthe sentinel of gut\u201d: their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics","volume":"13","author":"Singh","year":"2023","journal-title":"Front. Microbiol."},{"key":"ref38","doi-asserted-by":"publisher","first-page":"1638378","DOI":"10.3389\/fmicb.2025.1638378","article-title":"Application and utilization of fermentation as a processing tool to mitigate protein putrefaction in plant-based diets","volume":"16","author":"Sooraj","year":"2025","journal-title":"Front. Microbiol."},{"key":"ref39","doi-asserted-by":"publisher","first-page":"339","DOI":"10.2478\/aoas-2022-0080","article-title":"Pineapple waste in animal feed: a review of nutritional potential, impact and prospects","volume":"23","author":"Sukri","year":"2023","journal-title":"Ann. Anim. Sci."},{"key":"ref40","doi-asserted-by":"publisher","first-page":"114664","DOI":"10.1016\/j.anifeedsci.2020.114664","article-title":"Evaluation of pineapple byproduct at increasing levels in heavy finishing pigs feeding","volume":"269","author":"Vasconcelos","year":"2020","journal-title":"Anim. Feed Sci. Technol."},{"key":"ref41","doi-asserted-by":"publisher","first-page":"612285","DOI":"10.3389\/fbioe.2021.612285","article-title":"Metabolism characteristics of lactic acid bacteria and the expanding applications in food industry","volume":"9","author":"Wang","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"key":"ref42","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s12915-019-0699-4","article-title":"The human gut bacteria Christensenellaceae are widespread, heritable, and associated with health","volume":"17","author":"Waters","year":"2019","journal-title":"BMC Biol."},{"key":"ref43","doi-asserted-by":"publisher","first-page":"102823","DOI":"10.1016\/j.fbio.2023.103172","article-title":"The effect of lactic acid bacteria on lipid metabolism and flavor formation in fermented meat products","volume":"53","author":"Xia","year":"2023","journal-title":"Food Biosci."},{"key":"ref44","doi-asserted-by":"publisher","first-page":"1438878","DOI":"10.3389\/fmicb.2024.1438878","article-title":"The microbiota and metabolome dynamics and their interactions modulate solid-state fermentation process and enhance clean recycling of brewers\u2019 spent grain","volume":"15","author":"Xie","year":"2024","journal-title":"Front. Microbiol."},{"key":"ref45","doi-asserted-by":"publisher","first-page":"1347293","DOI":"10.3389\/fmicb.2024.1347293","article-title":"Effects of lactic acid bacteria inoculants on the nutrient composition, fermentation quality, and microbial diversity of whole-plant soybean-corn mixed silage","volume":"15","author":"Xu","year":"2024","journal-title":"Front. Microbiol."},{"key":"ref46","doi-asserted-by":"publisher","first-page":"107902","DOI":"10.1016\/j.fbio.2025.107902","article-title":"Exploring tannase and phytase enzymes from lactic acid bacteria: applications, challenges and future perspectives","volume":"74","author":"Yadav","year":"2025","journal-title":"Food Biosci."},{"key":"ref47","doi-asserted-by":"publisher","first-page":"e14814","DOI":"10.1016\/j.heliyon.2023.e14814","article-title":"Valorization of agro-industrial wastes into animal feed through microbial fermentation: a review of the global and Ghanaian case","volume":"9","author":"Yafetto","year":"2023","journal-title":"Heliyon"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"48","DOI":"10.3390\/fermentation10010048","article-title":"Effect of lactic acid bacteria fermentation on plant-based products","volume":"10","author":"Yang","year":"2024","journal-title":"Fermentation"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"123363","DOI":"10.1016\/j.carbpol.2025.123363","article-title":"Structural characteristics, biotechnological production and applications of exopolysaccharides from Bacillus sp.: a comprehensive review","volume":"355","author":"Yang","year":"2025","journal-title":"Carbohydr. Polym."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"2507905","DOI":"10.1080\/10495398.2025.2507905","article-title":"Quality and microbial community analysis of solid-state fermented feed with mixed bacteria from corn silage","volume":"36","author":"Yang","year":"2025","journal-title":"Anim. Biotechnol."},{"key":"ref51","doi-asserted-by":"publisher","first-page":"lxae254","DOI":"10.1093\/jambio\/lxae254","article-title":"Thermophile-fermented feed modulates the gut microbiota related to lactate metabolism in pigs","volume":"135","author":"Yoshikawa","year":"2024","journal-title":"J. Appl. Microbiol."},{"key":"ref52","doi-asserted-by":"publisher","first-page":"3600","DOI":"10.3390\/ani15243600","article-title":"Dietary pineapple pomace complex improves growth performance and reduces fecal odor in weaned piglets by modulating fecal microbiota, scfas, and indoles","volume":"15","author":"Yu","year":"2025","journal-title":"Animals"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1038\/nprot.2012.024","article-title":"A positive\/negative ion\u2013switching, targeted mass spectrometry\u2013based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue","volume":"7","author":"Yuan","year":"2012","journal-title":"Nat. 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