{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T07:05:28Z","timestamp":1793171128162,"version":"4.5.0"},"reference-count":81,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Mol. Biosci."],"DOI":"10.3389\/fmolb.2018.00023","type":"journal-article","created":{"date-parts":[[2018,3,20]],"date-time":"2018-03-20T04:23:46Z","timestamp":1521519826000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":17,"title":["XPD\u2013The Lynchpin of NER: Molecule, Gene, Polymorphisms, and Role in Colorectal Carcinogenesis"],"prefix":"10.3389","volume":"5","author":[{"given":"Aga Syed","family":"Sameer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saniya","family":"Nissar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,3,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"8332","DOI":"10.1158\/1078-0432.CCR-05-1030","article-title":"Microsatellite instability and CRC prognosis","volume":"11","author":"Benatti","year":"2005","journal-title":"Clin. Cancer Res."},{"key":"B2","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S1383-5742(00)00032-6","article-title":"Variability in nucleotide excision repair and cancer risk: a review","volume":"462","author":"Benhamou","year":"2000","journal-title":"Mutat. Res."},{"key":"B3","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1093\/mutage\/17.6.463","article-title":"ERCC2\/XPD gene polymorphisms and cancer risk","volume":"17","author":"Benhamou","year":"2002","journal-title":"Mutagenesis"},{"key":"B4","doi-asserted-by":"publisher","first-page":"2073","DOI":"10.1053\/j.gastro.2009.12.064","article-title":"Microsatellite instability in colorectal cancer","volume":"138","author":"Boland","year":"2010","journal-title":"Gastroenterology"},{"key":"B5","doi-asserted-by":"publisher","first-page":"22815","DOI":"10.1074\/jbc.M002578200","article-title":"Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities","volume":"275","author":"Busso","year":"2000","journal-title":"J. Biol. Chem."},{"key":"B6","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/1747-1028-5-24","article-title":"On the traces of XPD: cell cycle matters - untangling the genotype-phenotype relationship of XPD mutations","volume":"5","author":"Cameroni","year":"2010","journal-title":"Cell Div."},{"key":"B7","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/S0092-8674(00)00083-0","article-title":"Electron crystal structure of the transcription factor and DNA repair complex, core TFIIH","volume":"102","author":"Chang","year":"2000","journal-title":"Cell"},{"key":"B8","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/nature01746","article-title":"Xpd\/Ercc2 regulates CAK activity and mitotic progression","volume":"424","author":"Chen","year":"2003","journal-title":"Nature"},{"key":"B9","doi-asserted-by":"publisher","first-page":"503","DOI":"10.4161\/cc.2.6.558","article-title":"Xpd, a structural bridge and a functional link","volume":"2","author":"Chen","year":"2003","journal-title":"Cell Cycle"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1093\/emboj\/18.5.1357","article-title":"Mutations in XPB and XPD helicases found in xeroderma pigmentosum patients impair the transcription function of TFIIH","volume":"18","author":"Coin","year":"1999","journal-title":"EMBO J."},{"key":"B11","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/2491","article-title":"Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH","volume":"20","author":"Coin","year":"1998","journal-title":"Nat. Genet"},{"key":"B12","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.molcel.2007.03.009","article-title":"Distinct roles for the XPB\/p52 and XPD\/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair","volume":"26","author":"Coin","year":"2007","journal-title":"Mol. Cell"},{"key":"B13","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1038\/nrm3350","article-title":"TFIIH: when transcription met DNA repair","volume":"13","author":"Compe","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1030","DOI":"10.1016\/S0140-6736(10)60353-4","article-title":"Colorectal cancer","volume":"375","author":"Cunningham","year":"2010","journal-title":"Lancet"},{"key":"B15","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1101\/gad.13.7.768","article-title":"Molecular mechanism of nucleotide excision repair","volume":"13","author":"de Laat","year":"1999","journal-title":"Genes Dev."},{"key":"B16","doi-asserted-by":"publisher","first-page":"e96301","DOI":"10.1371\/journal.pone.0096301","article-title":"The effect of XPD polymorphisms on digestive tract cancers risk: a meta-analysis","volume":"9","author":"Du","year":"2014","journal-title":"PLoS ONE"},{"key":"B17","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.dnarep.2011.04.021","article-title":"A history of TFIIH: two decades of molecular biology on a pivotal transcription\/repair factor","volume":"10","author":"Egly","year":"2011","journal-title":"DNA Repair (Amst)"},{"key":"B18","doi-asserted-by":"publisher","first-page":"6559","DOI":"10.1093\/emboj\/16.21.6559","article-title":"Mechanism of open complex and dual incision formation by human nucleotide excision repair factors","volume":"16","author":"Evans","year":"1997","journal-title":"EMBO J."},{"key":"B19","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.cell.2008.04.030","article-title":"XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations","volume":"133","author":"Fan","year":"2008","journal-title":"Cell"},{"key":"B20","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/j.dnarep.2011.04.028","article-title":"XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase","volume":"10","author":"Fuss","year":"2011","journal-title":"DNA Repair (Amst)."},{"key":"B21","doi-asserted-by":"publisher","first-page":"5721","DOI":"10.7314\/APJCP.2012.13.11.5721","article-title":"Association between polymorphisms of XRCC1 Arg399Gln and XPD Lys751Gln genes and prognosis of colorectal cancer in a Chinese population","volume":"13","author":"Gan","year":"2012","journal-title":"Asian Pac. J. Cancer Prev."},{"key":"B22","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.mrgentox.2013.05.002","article-title":"The influence of XPD, APE1, XRCC1, and NBS1 polymorphic variants on DNA repair in cells exposed to X-rays","volume":"755","author":"Gdowicz-Klosok","year":"2013","journal-title":"Mutat. Res."},{"key":"B23","first-page":"1608","article-title":"Characterization of sporadic colon cancer by patterns of genomic instability","volume":"63","author":"Goel","year":"2003","journal-title":"Cancer Res."},{"key":"B24","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1023\/A:1025861527711","article-title":"Genomic instability and colon cancer","volume":"23","author":"Grady","year":"2004","journal-title":"Cancer Metastasis Rev."},{"key":"B25","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1038\/35077232","article-title":"Genome maintenance mechanisms for preventing cancer","volume":"411","author":"Hoeijmakers","year":"2001","journal-title":"Nature"},{"key":"B26","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.dnarep.2016.05.019","article-title":"Role of XPD in cellular functions: To TFIIH and beyond","volume":"44","author":"Houten","year":"2016","journal-title":"DNA Repair (Amst)"},{"key":"B27","doi-asserted-by":"publisher","first-page":"4121","DOI":"10.3390\/ijms14024121","article-title":"Polymorphisms in XPD and ERCC1 associated with colorectal cancer outcome","volume":"14","author":"Huang","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"B28","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S0092-8674(02)00729-8","article-title":"TFIIH plays an essential role in RNA polymerase I transcription","volume":"109","author":"Iben","year":"2002","journal-title":"Cell"},{"key":"B29","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1067\/mjd.2001.114294","article-title":"Trichothiodystrophy: update on the sulfur-deficient brittle hair syndromes","volume":"44","author":"Itin","year":"2001","journal-title":"J. Am. Acad Dermatol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.dnarep.2013.04.015","article-title":"DNA repair mechanisms in dividing and non-dividing cells","volume":"12","author":"Iyama","year":"2013","journal-title":"DNA Repair (Amst)."},{"key":"B31","doi-asserted-by":"publisher","first-page":"a012740","DOI":"10.1101\/cshperspect.a012740","article-title":"Repair of strand breaks by homologous recombination","volume":"5","author":"Jasin","year":"2013","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"B32","volume-title":"ABC of Colorectal Cancer, 1st Edn","author":"Kerr","year":"2001"},{"key":"B33","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s10555-010-9207-6","article-title":"DNA methylation markers in colorectal cancer","volume":"29","author":"Kim","year":"2010","journal-title":"Cancer Metastasis Rev."},{"key":"B34","doi-asserted-by":"publisher","first-page":"2452","DOI":"10.1101\/gad.824700","article-title":"Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription","volume":"14","author":"Komarnitsky","year":"2000","journal-title":"Genes Dev."},{"key":"B35","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1016\/j.cell.2008.04.029","article-title":"Structure of the DNA repair helicase XPD","volume":"133","author":"Liu","year":"2008","journal-title":"Cell"},{"key":"B36","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1093\/carcin\/21.4.551","article-title":"XPD polymorphisms: effects on DNA repair proficiency","volume":"21","author":"Lunn","year":"2000","journal-title":"Carcinogenesis"},{"key":"B37","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1007\/s11033-013-2910-y","article-title":"Meta-analysis on the association of nucleotide excision repair gene XPD A751C variant and cancer susceptibility among Indian population","volume":"41","author":"Mandal","year":"2014","journal-title":"Mol. Biol. Rep."},{"key":"B38","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1038\/embor.2012.61","article-title":"Cancer chromosomal instability: therapeutic and diagnostic challenges","volume":"13","author":"McGranahan","year":"2012","journal-title":"EMBO Rep."},{"key":"B39","doi-asserted-by":"publisher","first-page":"237","DOI":"10.2174\/156652412799218859","article-title":"DNA repair mechanisms in colorectal carcinogenesis","volume":"12","author":"Michailidi","year":"2012","journal-title":"Curr. Mol. Med."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2011\/792362","article-title":"Genetics, cytogenetics and epigenetics of colorectal cancer","volume":"1","author":"Migliore","year":"2011","journal-title":"J. Biomed. Biotechnol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"3554","DOI":"10.1093\/emboj\/20.13.3554","article-title":"Double check probing of DNA bending and unwinding by XPA-RPA: an architectural function in DNA repair","volume":"20","author":"Missura","year":"2001","journal-title":"EMBO J."},{"key":"B42","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1007\/s12032-014-0942-3","article-title":"No association between XRCC3 Thr241Met and XPD Lys751Gln polymorphisms and the risk of colorectal cancer in West Algerian population: a case-control study","volume":"31","author":"Moghtit","year":"2014","journal-title":"Med. Oncol."},{"key":"B43","first-page":"1054","article-title":"Identification of 127 amino acid substitution variants in screening 37 DNA repair genes in humans","volume":"11","author":"Mohrenweiser","year":"2002","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"B44","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1093\/carcin\/bgs107","article-title":"Deciphering the role of the ERCC2 gene polymorphism on anticancer drug sensitivity","volume":"33","author":"Moisan","year":"2012","journal-title":"Carcinogenesis"},{"key":"B45","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/S0304-3835(99)00414-0","article-title":"Psoriasis patients with basal cell carcinoma have more repair-mediated DNA strand-breaks after UVC damage in lymphocytes than psoriasis patients without basal cell carcinoma","volume":"151","author":"M\u00f8ller","year":"2000","journal-title":"Cancer Lett."},{"key":"B46","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1158\/1078-0432.CCR-05-1363","article-title":"Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer","volume":"12","author":"Moreno","year":"2006","journal-title":"Clin. Cancer Res."},{"key":"B47","doi-asserted-by":"publisher","first-page":"287","DOI":"10.4149\/neo_2010_04_287","article-title":"Transcription factor IIH - the protein complex with multiple functions","volume":"57","author":"Mydlikova","year":"2010","journal-title":"Neoplasma"},{"key":"B48","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1007\/s00018-009-8737-y","article-title":"DNA repair in mammalian cells: nucleotide excision repair: variations on versatility","volume":"66","author":"Nouspikel","year":"2009","journal-title":"Cell. Mol. Life Sci."},{"key":"B49","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1136\/gut.2010.217182","article-title":"Molecular pathological epidemiology of colorectal neoplasia: an emerging trans disciplinary and interdisciplinary field","volume":"60","author":"Ogino","year":"2011","journal-title":"Gut"},{"key":"B50","doi-asserted-by":"publisher","first-page":"2971","DOI":"10.1038\/emboj.2009.230","article-title":"Molecular insights into the recruitment of TFIIH to sites of DNA damage","volume":"28","author":"Oksenych","year":"2009","journal-title":"EMBO J."},{"key":"B51","doi-asserted-by":"publisher","first-page":"90","DOI":"10.4161\/cc.9.1.10267","article-title":"The long unwinding road: XPB and XPD helicases in damaged DNA opening","volume":"9","author":"Oksenych","year":"2010","journal-title":"Cell Cycle"},{"key":"B52","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1007\/s11033-014-3824-z","article-title":"Polymorphisms in nucleotide excision repair genes and susceptibility to colorectal cancer in the Polish population","volume":"42","author":"Paszkowska-Szczur","year":"2015","journal-title":"Mol. Biol. Rep."},{"key":"B53","doi-asserted-by":"crossref","first-page":"23","DOI":"10.32607\/20758251-2014-6-1-23-34","article-title":"Molecular mechanism of global genome nucleotide excision repair","volume":"6","author":"Petruseva","year":"2014","journal-title":"Acta Naturae"},{"key":"B54","doi-asserted-by":"publisher","first-page":"711","DOI":"10.19041\/Apstract\/2013\/4-5\/17","article-title":"Lys751Gln, X. P. D., and Arg399Gln XRCC1 in Romanians. Association with sporadic colorectal cancer risk and different stages of carcinomas","volume":"108","author":"Procopciuc","year":"2013","journal-title":"Chirurgia (Bucur)"},{"key":"B55","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1093\/carcin\/23.2.295","article-title":"Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD\/ERCC2 genotypes","volume":"23","author":"Qiao","year":"2002","journal-title":"Carcinogenesis"},{"key":"B56","first-page":"18","article-title":"Relationship between XPD Lys 751 Gln polymorphism and colorectal cancer risk: a case-control study in a population-based study","volume":"6","author":"Rezaei","year":"2013","journal-title":"Gastroenterol. Hepatol. Bed. Bench"},{"key":"B57","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/j.jmb.2007.12.019","article-title":"The archaeal XPB protein is a ssDNA-dependent ATPase with a novel partner","volume":"376","author":"Richards","year":"2008","journal-title":"J. Mol. Biol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1016\/j.molcel.2006.07.019","article-title":"The DNA repair helicases XPD and FancJ have essential iron-sulfur domains","volume":"23","author":"Rudolf","year":"2006","journal-title":"Mol. Cell"},{"key":"B59","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1093\/nar\/gkp1058","article-title":"The helicase XPD unwinds bubble structures and is not stalled by DNA lesions removed by the nucleotide excision repair pathway","volume":"38","author":"Rudolf","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"B60","doi-asserted-by":"publisher","first-page":"114","DOI":"10.3389\/fonc.2013.00114","article-title":"Colorectal cancer: Molecular mutations and polymorphisms","volume":"3","author":"Sameer","year":"2013","journal-title":"Front. Oncol."},{"key":"B61","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s11888-016-0317-6","article-title":"Understanding epigenetics: an alternative mechanism of colorectal carcinogenesis","volume":"12","author":"Sameer","year":"2016","journal-title":"Curr. Colorectal Cancer Rep."},{"key":"B62","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1097\/CEJ.0000000000000019","article-title":"Mismatch repair pathway: molecules, functions, and role in colorectal carcinogenesis","volume":"23","author":"Sameer","year":"2014","journal-title":"Eur. J. Cancer Prev."},{"key":"B63","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1038\/363371a0","article-title":"Phosphorylation of C-terminal domain of RNA polymerase II is not required in basal transcription","volume":"363","author":"Serizawa","year":"1993","journal-title":"Nature"},{"key":"B64","first-page":"604","article-title":"Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans","volume":"58","author":"Shen","year":"1998","journal-title":"Cancer Res."},{"key":"B65","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/1471-2407-6-67","article-title":"Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study","volume":"6","author":"Skjelbred","year":"2006","journal-title":"BMC Cancer"},{"key":"B66","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1620\/tjem.218.185","article-title":"Common polymorphisms in the XPD and hOGG1 genes are not associated with the risk of colorectal cancer in a Polish population","volume":"218","author":"Sliwinski","year":"2009","journal-title":"Tohoku J. Exp. Med."},{"key":"B67","first-page":"1354","article-title":"Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients","volume":"61","author":"Spitz","year":"2001","journal-title":"Cancer Res."},{"key":"B68","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.dnarep.2015.09.003","article-title":"Nucleotide excision repair in humans","volume":"36","author":"Spivak","year":"2015","journal-title":"DNA Repair (Amst)"},{"key":"B69","doi-asserted-by":"publisher","first-page":"2384","DOI":"10.1158\/1055-9965.EPI-06-0381","article-title":"XRCC1, XRCC3, and XPD polymorphisms as modifiers of the effect of smoking and alcohol on colorectal adenoma risk","volume":"15","author":"Stern","year":"2006","journal-title":"Cancer"},{"key":"B70","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/S1097-2765(00)80177-X","article-title":"Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB XPD and cdk7","volume":"3","author":"Tirode","year":"1999","journal-title":"Mol. Cell"},{"key":"B71","doi-asserted-by":"publisher","first-page":"8681","DOI":"10.1073\/pnas.96.15.8681","article-title":"CpG island methylator phenotype in colorectal cancer","volume":"96","author":"Toyota","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B72","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1056\/NEJM198809013190901","article-title":"Genetic alterations during colorectal-tumor development","volume":"319","author":"Vogelstein","year":"1988","journal-title":"N. Engl. J. Med."},{"key":"B73","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1007\/s00432-010-0809-8","article-title":"Polymorphisms in DNA repair genes XRCC1, XRCC3 and XPD, and colorectal cancer risk: a case-control study in an Indian population","volume":"136","author":"Wang","year":"2010","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"4258","DOI":"10.1074\/jbc.275.6.4258","article-title":"TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair","volume":"275","author":"Winkler","year":"2000","journal-title":"J. Biol. Chem."},{"key":"B75","doi-asserted-by":"publisher","first-page":"e149","DOI":"10.1371\/journal.pbio.0060149","article-title":"Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD","volume":"6","author":"Wolski","year":"2008","journal-title":"PLoS Biol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1515\/bc.2010.076","article-title":"The XPD helicase: XPanDing archaeal XPD structures to get a grip on human DNA repair","volume":"391","author":"Wolski","year":"2010","journal-title":"Biol. Chem."},{"key":"B77","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/1471-2407-5-12","article-title":"Polymorphisms of the XRCC1, XRCC3, & XPD genes, and colorectal cancer risk: a case-control study in Taiwan","volume":"5","author":"Yeh","year":"2005","journal-title":"BMC Cancer"},{"key":"B78","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.2147\/OTT.S66291","article-title":"Lack of association between the XPD Lys751Gln polymorphism and colorectal cancer risk: a meta-analysis","volume":"7","author":"Zhang","year":"2014","journal-title":"Onco. Targets. Ther."},{"key":"B79","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1007\/s00384-011-1222-8","article-title":"Lack of association between XPD Lys751Gln and Asp312Asn polymorphisms and colorectal cancer risk: a meta-analysis of case-control studies","volume":"26","author":"Zhang","year":"2011","journal-title":"Int. J. Colorectal Dis."},{"key":"B80","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1100\/tsw.2010.46","article-title":"Two sides of the same coin: TFIIH complexes in transcription and DNA repair","volume":"10","author":"Zhovmer","year":"2010","journal-title":"Sci. World J."},{"key":"B81","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.tig.2003.08.005","article-title":"The transcriptional complexity of the TFIIH complex","volume":"19","author":"Zurita","year":"2003","journal-title":"Trends Genet."}],"container-title":["Frontiers in Molecular Biosciences"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fmolb.2018.00023\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,13]],"date-time":"2019-10-13T04:22:43Z","timestamp":1570940563000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fmolb.2018.00023\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,20]]},"references-count":81,"alternative-id":["10.3389\/fmolb.2018.00023"],"URL":"https:\/\/doi.org\/10.3389\/fmolb.2018.00023","relation":{},"ISSN":["2296-889X"],"issn-type":[{"value":"2296-889X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,20]]},"article-number":"23"}}