{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T06:42:17Z","timestamp":1782456137387,"version":"3.54.5"},"reference-count":86,"publisher":"Frontiers Media SA","funder":[{"DOI":"10.13039\/501100003006","name":"Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich","doi-asserted-by":"publisher","award":["ET-17 13-2"],"award-info":[{"award-number":["ET-17 13-2"]}],"id":[{"id":"10.13039\/501100003006","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Aging Neurosci."],"DOI":"10.3389\/fnagi.2016.00283","type":"journal-article","created":{"date-parts":[[2016,11,29]],"date-time":"2016-11-29T03:17:12Z","timestamp":1480389432000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Combining Exergame Training with Omega-3 Fatty Acid Supplementation: Protocol for a Randomized Controlled Study Assessing the Effect on Neuronal Structure\/Function in the Elderly Brain"],"prefix":"10.3389","volume":"8","author":[{"given":"Alexandra","family":"Sch\u00e4ttin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eling D.","family":"de Bruin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2016,11,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"20130152","DOI":"10.1098\/rstb.2013.0152","article-title":"Functional MRI of long-term potentiation: imaging network plasticity","volume":"369","author":"Alvarez-Salvado","year":"2014","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"B2","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/BF02513304","article-title":"Physical activity monitoring based on accelerometry: validation and comparison with video observation","volume":"37","author":"Aminian","year":"1999","journal-title":"Med. Biol. Eng. Comput."},{"key":"B3","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1038\/nature12486","article-title":"Video game training enhances cognitive control in older adults","volume":"501","author":"Anguera","year":"2013","journal-title":"Nature"},{"key":"B4","doi-asserted-by":"crossref","first-page":"1467S","DOI":"10.1093\/ajcn\/83.6.1467S","article-title":"Distribution, interconversion, and dose response of n-3 fatty acids in humans","volume":"83","author":"Arterburn","year":"2006","journal-title":"Am. J. Clin. Nutr."},{"key":"B5","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1016\/j.neubiorev.2006.06.005","article-title":"The correlative triad among aging, dopamine, and cognition: current status and future prospects","volume":"30","author":"B\u00e4ckman","year":"2006","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B6","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.neubiorev.2014.03.019","article-title":"A review of physical and cognitive interventions in aging","volume":"44","author":"Bamidis","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B7","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1016\/j.neubiorev.2008.09.010","article-title":"Cognitive control mechanisms, emotion and memory: a neural perspective with implications for psychopathology","volume":"33","author":"Banich","year":"2009","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B8","doi-asserted-by":"publisher","first-page":"295","DOI":"10.7326\/0003-4819-148-4-200802190-00008","article-title":"Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration","volume":"148","author":"Boutron","year":"2008","journal-title":"Ann. Intern. Med."},{"key":"B9","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1016\/j.biopsych.2006.01.011","article-title":"Regional white matter and neuropsychological functioning across the adult lifespan","volume":"60","author":"Brickman","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"B10","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.clinph.2008.11.019","article-title":"Reliability of transcranial magnetic stimulation-related measurements of tibialis anterior muscle in healthy subjects","volume":"120","author":"Cacchio","year":"2009","journal-title":"Clin. Neurophysiol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3389\/fnagi.2014.00031","article-title":"Brain plasticity and motor practice in cognitive aging","volume":"6","author":"Cai","year":"2014","journal-title":"Front. Aging Neurosci."},{"key":"B12","doi-asserted-by":"publisher","first-page":"200","DOI":"10.7326\/0003-4819-158-3-201302050-00583","article-title":"SPIRIT 2013 statement: defining standard protocol items for clinical trials","volume":"158","author":"Chan","year":"2013","journal-title":"Ann. Intern. Med."},{"key":"B13","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.brainres.2009.05.018","article-title":"Exercise contributes to the effects of DHA dietary supplementation by acting on membrane-related synaptic systems","volume":"1341","author":"Chytrova","year":"2010","journal-title":"Brain Res."},{"key":"B14","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1093\/gerona\/58.2.M176","article-title":"Aerobic fitness reduces brain tissue loss in aging humans","volume":"58","author":"Colcombe","year":"2003","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1111\/1467-9280.t01-1-01430","article-title":"Fitness effects on the cognitive function of older adults: a meta-analytic study","volume":"14","author":"Colcombe","year":"2003","journal-title":"Psychol. Sci."},{"key":"B16","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/j.tins.2007.06.011","article-title":"Exercise builds brain health: key roles of growth factor cascades and inflammation","volume":"30","author":"Cotman","year":"2007","journal-title":"Trends Neurosci."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.3945\/ajcn.2009.29121","article-title":"Effect of 2-y n-3 long-chain polyunsaturated fatty acid supplementation on cognitive function in older people: a randomized, double-blind, controlled trial","volume":"91","author":"Dangour","year":"2010","journal-title":"Am. J. Clin. Nutr."},{"key":"B18","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/j.neuroimage.2009.01.068","article-title":"Assessing the effects of age on long white matter tracts using diffusion tensor tractography","volume":"46","author":"Davis","year":"2009","journal-title":"NeuroImage"},{"key":"B19","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1682\/JRRD.2006.01.0003","article-title":"Quantification of everyday motor function in a geriatric population","volume":"44","author":"de Bruin","year":"2007","journal-title":"J. Rehabil. Res. Dev."},{"key":"B20","doi-asserted-by":"publisher","first-page":"104","DOI":"10.4172\/2165-7025.1000104","article-title":"Feasibility of strength-balance training extended with computer game dancing in older people; does it affect dual task costs of walking?","volume":"1","author":"de Bruin","year":"2011","journal-title":"J. Nov. Physiother."},{"key":"B21","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/1744-9081-6-59","article-title":"Walking behaviour of healthy elderly: attention should be paid","volume":"6","author":"de Bruin","year":"2010","journal-title":"Behav. Brain Funct."},{"key":"B22","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1177\/0269215512453352","article-title":"A randomized controlled pilot study assessing the feasibility of combined motor\u2013cognitive training and its effect on gait characteristics in the elderly","volume":"27","author":"de Bruin","year":"2013","journal-title":"Clin. Rehabil."},{"key":"B23","first-page":"1184","article-title":"Functional and pathophysiological models of the basal ganglia: therapeutic implications","volume":"40","author":"DeLong","year":"2000","journal-title":"Rinsho Shinkeigaku"},{"key":"B24","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/PL00005641","article-title":"Input-output properties and gain changes in the human corticospinal pathway","volume":"114","author":"Devanne","year":"1997","journal-title":"Exp. Brain Res."},{"key":"B25","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.humov.2006.03.004","article-title":"Relationships between dual-task related changes in stride velocity and stride time variability in healthy older adults","volume":"25","author":"Dubost","year":"2006","journal-title":"Hum. Mov. Sci."},{"key":"B26","doi-asserted-by":"publisher","first-page":"66","DOI":"10.3389\/fnagi.2016.00066","article-title":"Exergame and balance training modulate prefrontal brain activity during walking and enhance executive function in older adults","volume":"8","author":"Eggenberger","year":"2016","journal-title":"Front. Aging Neurosci."},{"key":"B27","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1515\/REVNEURO.2010.21.3.187","article-title":"Structural brain changes in aging: courses, causes and cognitive consequences","volume":"21","author":"Fjell","year":"2010","journal-title":"Rev. Neurosci."},{"key":"B28","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J. Psychiatr. Res."},{"key":"B29","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1111\/j.1365-2362.2005.01570.x","article-title":"Cognitive and physiological effects of Omega-3 polyunsaturated fatty acid supplementation in healthy subjects","volume":"35","author":"Fontani","year":"2005","journal-title":"Eur. J. Clin. Invest."},{"key":"B30","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1038\/nrn2421","article-title":"Brain foods: the effects of nutrients on brain function","volume":"9","author":"G\u00f3mez-Pinilla","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"B31","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.neuroscience.2010.02.070","article-title":"Differential effects of exercise and dietary docosahexaenoic acid on molecular systems associated with control of allostasis in the hypothalamus and hippocampus","volume":"168","author":"Gomez-Pinilla","year":"2010","journal-title":"Neuroscience"},{"key":"B32","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1037\/a0014345","article-title":"Exercising your brain: a review of human brain plasticity and training-induced learning","volume":"23","author":"Green","year":"2008","journal-title":"Psychol. Aging"},{"key":"B33","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1002\/gps.2087","article-title":"Aging of cerebral white matter: a review of MRI findings","volume":"24","author":"Gunning-Dixon","year":"2009","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"B34","doi-asserted-by":"publisher","first-page":"1929","DOI":"10.1016\/S0028-3932(03)00129-5","article-title":"Neuroanatomical correlates of selected executive functions in middle-aged and older adults: a prospective MRI study","volume":"41","author":"Gunning-Dixon","year":"2003","journal-title":"Neuropsychologia"},{"key":"B35","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.plefa.2014.01.002","article-title":"Impact of fatty acids on brain circulation, structure and function","volume":"92","author":"Haast","year":"2015","journal-title":"Prostaglandins Leukot. Essent. Fatty Acids"},{"key":"B36","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1007\/s00221-005-2280-3","article-title":"Walking is more like catching than tapping: gait in the elderly as a complex cognitive task","volume":"164","author":"Hausdorff","year":"2005","journal-title":"Exp. Brain Res."},{"key":"B37","doi-asserted-by":"publisher","first-page":"131","DOI":"10.3389\/fpsyg.2014.00131","article-title":"Training principles to advance expertise","volume":"5","author":"Healy","year":"2014","journal-title":"Front. Psychol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"g1687","DOI":"10.1136\/bmj.g1687","article-title":"Better reporting of interventions: template for intervention description and replication (TIDieR) checklist and guide","volume":"348","author":"Hoffmann","year":"2014","journal-title":"BMJ"},{"key":"B39","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1037\/0894-4105.20.2.215","article-title":"Cognitive processes related to gait velocity: results from the Einstein Aging Study","volume":"20","author":"Holtzer","year":"2006","journal-title":"Neuropsychology"},{"key":"B40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.plipres.2013.10.002","article-title":"Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration","volume":"53","author":"Janssen","year":"2014","journal-title":"Prog. Lipid Res."},{"key":"B41","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/S0197-2456(01)00139-8","article-title":"ACTIVE: a cognitive intervention trial to promote independence in older adults","volume":"22","author":"Jobe","year":"2001","journal-title":"Control. Clin. Trials"},{"key":"B42","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1016\/S0022-2275(20)37132-7","article-title":"Kinetics of the incorporation of dietary fatty acids into serum cholesteryl esters, erythrocyte membranes, and adipose tissue: an 18-month controlled study","volume":"38","author":"Katan","year":"1997","journal-title":"J. Lipid Res."},{"key":"B43","doi-asserted-by":"publisher","first-page":"e20","DOI":"10.1161\/01.CIR.0000038493.65177.94","article-title":"Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease","volume":"23","author":"Kris-Etherton","year":"2003","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"e40588","DOI":"10.1371\/journal.pone.0040588","article-title":"Computerized cognitive training with older adults: a systematic review","volume":"7","author":"Kueider","year":"2012","journal-title":"PLoS ONE"},{"key":"B45","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.arr.2014.02.008","article-title":"Effects of combined cognitive and exercise interventions on cognition in older adults with and without cognitive impairment: a systematic review","volume":"15","author":"Law","year":"2014","journal-title":"Ageing Res. Rev."},{"key":"B46","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1161\/01.STR.27.8.1274","article-title":"Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. The cardiovascular health study","volume":"27","author":"Longstreth","year":"1996","journal-title":"Stroke"},{"issue":"Pt 12","key":"B47","doi-asserted-by":"publisher","first-page":"2304","DOI":"10.1242\/jeb.02208","article-title":"Neuron-glia metabolic coupling and plasticity","volume":"209","author":"Magistretti","year":"2006","journal-title":"J. Exp. Biol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"3162","DOI":"10.1109\/TBME.2012.2216263","article-title":"Heel and toe clearance estimation for gait analysis using wireless inertial sensors","volume":"59","author":"Mariani","year":"2012","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"B49","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1093\/geronj\/41.6.764","article-title":"The effects of age and extended practice on divided attention performance","volume":"41","author":"McDowd","year":"1986","journal-title":"J. Gerontol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1093\/ajh\/hpu024","article-title":"Long-chain omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and blood pressure: a meta-analysis of randomized controlled trials","volume":"27","author":"Miller","year":"2014","journal-title":"Am. J. Hypertens."},{"key":"B51","doi-asserted-by":"publisher","first-page":"e40297","DOI":"10.1371\/journal.pone.0040297","article-title":"Executive function and falls in older adults: new findings from a five-year prospective study link fall risk to cognition","volume":"7","author":"Mirelman","year":"2012","journal-title":"PLoS ONE"},{"key":"B52","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1093\/ageing\/afr103","article-title":"Older people's participation in and engagement with falls prevention interventions in community settings: an augment to the Cochrane systematic review","volume":"41","author":"Nyman","year":"2012","journal-title":"Age Ageing"},{"key":"B53","doi-asserted-by":"publisher","first-page":"175","DOI":"10.2147\/CIA.S32558","article-title":"The effect of a cognitive-motor intervention on voluntary step execution under single and dual task conditions in older adults: a randomized controlled pilot study","volume":"7","author":"Pichierri","year":"2012b","journal-title":"Clin. Interv. Aging"},{"key":"B54","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1186\/1471-2318-12-74","article-title":"A cognitive-motor intervention using a dance video game to enhance foot placement accuracy and gait under dual task conditions in older adults: a randomized controlled trial","volume":"12","author":"Pichierri","year":"2012a","journal-title":"BMC Geriatr."},{"key":"B55","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/S0003-9993(98)90035-1","article-title":"Executive functioning and predictors of falls in the rehabilitation setting","volume":"79","author":"Rapport","year":"1998","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"B56","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0021-9673(97)10554-4","article-title":"Comparison of two methods for the determination of fatty acid profiles in plasma and erythrocytes","volume":"793","author":"Rodriguez-Palmero","year":"1998","journal-title":"J. Chromatogr. A"},{"key":"B57","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1093\/ageing\/afr113","article-title":"Slower gait, slower information processing and smaller prefrontal area in older adults","volume":"41","author":"Rosano","year":"2012","journal-title":"Age Ageing"},{"key":"B58","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/0013-4694(94)90029-9","article-title":"Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee","volume":"91","author":"Rossini","year":"1994","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"B59","article-title":"Enobio-first tests of a dry electrophysiology electrode using carbon nanotubes","volume-title":"Engineering in Medicine and Biology Societ, EMBS'06 28th Annual International Conference of the IEEE","year":"2006"},{"key":"B60","article-title":"ENOBIO dry electrophysiology electrode; first human trial plus wireless electrode system","volume-title":"Engineering in Medicine and Biology Society, 2007 EMBS 2007 29th Annual International Conference of the IEEE","year":"2007"},{"key":"B61","doi-asserted-by":"publisher","first-page":"278","DOI":"10.3389\/fnagi.2016.00278","article-title":"Adaptations of prefrontal brain activity, executive functions, and gait in healthy elderly following exergame and balance training: a randomized-controlled study","volume":"8","author":"Sch\u00e4ttin","year":"2016","journal-title":"Front. Aging Neurosci."},{"key":"B62","doi-asserted-by":"publisher","first-page":"161","DOI":"10.3389\/fnagi.2016.00161","article-title":"Effects of physical exercise combined with nutritional supplements on aging brain related structures and functions: a systematic review","volume":"8","author":"Sch\u00e4ttin","year":"2016","journal-title":"Front. Aging Neurosci."},{"key":"B63","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/j.neubiorev.2010.08.009","article-title":"Understanding higher level gait disturbances in mild dementia in order to improve rehabilitation: \u2018last in-first out\u2019","volume":"35","author":"Scherder","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B64","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.bbr.2010.11.058","article-title":"The cholinergic system in aging and neuronal degeneration","volume":"221","author":"Schliebs","year":"2011","journal-title":"Behav. Brain Res."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1586\/ern.11.69","article-title":"The interplay between gait, falls and cognition: can cognitive therapy reduce fall risk?","volume":"11","author":"Segev-Jacubovski","year":"2011","journal-title":"Expert Rev. Neurother."},{"key":"B66","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.1046\/j.1532-5415.2003.51516.x","article-title":"Influence of executive function on locomotor function: divided attention increases gait variability in Alzheimer's disease","volume":"51","author":"Sheridan","year":"2003","journal-title":"J. Am. Geriatr. Soc."},{"key":"B67","doi-asserted-by":"publisher","first-page":"2730","DOI":"10.3390\/nu6072730","article-title":"Does consumption of LC Omega-3 PUFA enhance cognitive performance in healthy school-aged children and throughout adulthood?","volume":"6","author":"Stonehouse","year":"2014","journal-title":"Evid. Clin. Trials Nutr."},{"key":"B68","doi-asserted-by":"publisher","first-page":"2154","DOI":"10.1161\/CIRCULATIONAHA.113.002731","article-title":"Omega-3 fatty acid blood levels: clinical significance and controversy","volume":"128","author":"Superko","year":"2013","journal-title":"Circulation"},{"key":"B69","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1007\/s00702-007-0749-x","article-title":"Higher level gait disorders","volume":"114","author":"Thompson","year":"2007","journal-title":"J. Neural Transm."},{"key":"B70","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1111\/j.1532-5415.1992.tb01992.x","article-title":"The mini-mental state examination: a comprehensive review","volume":"40","author":"Tombaugh","year":"1992","journal-title":"J. Am. Geriatr. Soc."},{"key":"B71","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.mad.2013.12.005","article-title":"Effect of resistance-type exercise training with or without protein supplementation on cognitive functioning in frail and pre-frail elderly: secondary analysis of a randomized, double-blind, placebo-controlled trial","volume":"137","author":"van de Rest","year":"2014","journal-title":"Mech. Ageing Dev."},{"key":"B72","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.tins.2008.12.007","article-title":"Exercise and the brain: something to chew on","volume":"32","author":"van Praag","year":"2009","journal-title":"Trends Neurosci."},{"key":"B73","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1176\/ajp.155.3.344","article-title":"Association between decline in brain dopamine activity with age and cognitive and motor impairment in healthy individuals","volume":"155","author":"Volkow","year":"1998","journal-title":"Am. J. Psychiatry"},{"key":"B74","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.tics.2013.08.001","article-title":"Bridging animal and human models of exercise-induced brain plasticity","volume":"17","author":"Voss","year":"2013","journal-title":"Trends Cogn. Sci."},{"key":"B75","doi-asserted-by":"publisher","first-page":"PL187","DOI":"10.1016\/0024-3205(95)02099-5","article-title":"Comparison of two pet radioligands for imaging extrastriatal dopamine transporters in human brain","volume":"57","author":"Wang","year":"1995","journal-title":"Life Sci."},{"key":"B76","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1002\/(SICI)1098-2396(199809)30:156::AID-SYN73.0.CO;2-J","article-title":"Age-dependent decline of dopamine D1 receptors in human brain: a PET study","volume":"30","author":"Wang","year":"1998","journal-title":"Synapse"},{"key":"B77","doi-asserted-by":"publisher","first-page":"3059","DOI":"10.1093\/cercor\/bht163","article-title":"Long-chain omega-3 fatty acids improve brain function and structure in older adults","volume":"24","author":"Witte","year":"2014","journal-title":"Cereb. Cortex"},{"key":"B78","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/j.neuroscience.2008.05.061","article-title":"Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition","volume":"155","author":"Wu","year":"2008","journal-title":"Neuroscience"},{"key":"B79","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/s11556-009-0049-6","article-title":"Effects of motor practice on cognitive disorders in older adults","volume":"6","author":"Yan","year":"2009","journal-title":"Eur. Rev. Aging Phys. A"},{"key":"B80","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/0022-3956(82)90033-4","article-title":"Development and validation of a geriatric depression screening scale: a preliminary report","volume":"17","author":"Yesavage","year":"1983","journal-title":"J. Psychiatr. Res."},{"key":"B81","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1300\/J018v05n01_09","article-title":"9\/Geriatric Depression Scale (GDS) recent evidence and development of a shorter violence","volume":"5","author":"Yesavage","year":"1986","journal-title":"Clin. Gerontol."},{"key":"B82","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1002\/mds.21720","article-title":"The role of executive function and attention in gait","volume":"23","author":"Yogev-Seligmann","year":"2008","journal-title":"Mov. Disord."},{"key":"B83","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.neubiorev.2014.02.005","article-title":"Prefrontal cortex and executive functions in healthy adults: a meta-analysis of structural neuroimaging studies","volume":"42","author":"Yuan","year":"2014","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B84","doi-asserted-by":"publisher","first-page":"220","DOI":"10.4017\/gt.2009.08.04.004.00","article-title":"Cognitive benefits of computer games for older adults","volume":"8","author":"Zelinski","year":"2009","journal-title":"Gerontechnology"},{"key":"B85","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1097\/01.JGP.0000238502.40963.ac","article-title":"The relationship between frontal gray matter volume and cognition varies across the healthy adult lifespan","volume":"14","author":"Zimmerman","year":"2006","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"B86","first-page":"110","article-title":"A test battery for attentional performance","volume-title":"Applied Neurophyschology of Attention Theory, Diagnosis and Rehabilitation","author":"Zimmermann","year":"2002"}],"container-title":["Frontiers in Aging Neuroscience"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fnagi.2016.00283\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T08:13:43Z","timestamp":1657872823000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fnagi.2016.00283\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,29]]},"references-count":86,"URL":"https:\/\/doi.org\/10.3389\/fnagi.2016.00283","relation":{},"ISSN":["1663-4365"],"issn-type":[{"value":"1663-4365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,29]]}}}