{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:20:08Z","timestamp":1787026808963,"version":"build-2736575974"},"reference-count":37,"publisher":"Frontiers Media SA","funder":[{"DOI":"10.13039\/100004411","name":"Heart and Stroke Foundation of Canada","doi-asserted-by":"publisher","award":["Canadian Partnership for Stroke RecoveryCatalyst Grant"],"award-info":[{"award-number":["Canadian Partnership for Stroke RecoveryCatalyst Grant"]}],"id":[{"id":"10.13039\/100004411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Aging Neurosci."],"DOI":"10.3389\/fnagi.2017.00318","type":"journal-article","created":{"date-parts":[[2017,9,29]],"date-time":"2017-09-29T00:43:25Z","timestamp":1506645805000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":29,"title":["Exercise Training Increases Parietal Lobe Cerebral Blood Flow in Chronic Stroke: An Observational Study"],"prefix":"10.3389","volume":"9","author":[{"given":"Andrew D.","family":"Robertson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Marzolini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura E.","family":"Middleton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo S.","family":"Basile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul I.","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley J.","family":"MacIntosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,9,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1002\/mrm.25607","article-title":"Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: a consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia","volume":"73","author":"Alsop","year":"2015","journal-title":"Magn. Reson. Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"224","DOI":"10.3389\/fnagi.2015.00224","article-title":"Impaired cerebrovascular function in coronary artery disease patients and recovery following cardiac rehabilitation","volume":"7","author":"Anazodo","year":"2015","journal-title":"Front. Aging Neurosci."},{"key":"B3","doi-asserted-by":"publisher","first-page":"2532","DOI":"10.1161\/STR.0000000000000022","article-title":"Physical activity and exercise recommendations for stroke survivors: a statement for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"45","author":"Billinger","year":"2014","journal-title":"Stroke"},{"key":"B4","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/s0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurement","volume":"1","author":"Bland","year":"1986","journal-title":"Lancet"},{"key":"B5","doi-asserted-by":"publisher","first-page":"75","DOI":"10.3389\/fnagi.2013.00075","article-title":"Shorter term aerobic exercise improves brain, cognition, and cardiovascular fitness in aging","volume":"5","author":"Chapman","year":"2013","journal-title":"Front. Aging Neurosci."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.1016\/j.neurobiolaging.2013.12.008","article-title":"Cardiovascular risks and brain function: a functional magnetic resonance imaging study of executive function in older adults","volume":"35","author":"Chuang","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"B7","doi-asserted-by":"publisher","first-page":"164","DOI":"10.3389\/fnagi.2016.00164","article-title":"Influence of aerobic training and combinations of interventions on cognition and neuroplasticity after stroke","volume":"8","author":"Constans","year":"2016","journal-title":"Front. Aging Neurosci."},{"key":"B8","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1159\/000016009","article-title":"Bihemispheric contribution to motor recovery after stroke: a longitudinal study with transcranial doppler ultrasonography","volume":"9","author":"Cuadrado","year":"1999","journal-title":"Cerebrovasc. Dis."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1007\/s00259-003-1194-1","article-title":"Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer\u2019s disease: a PET follow-up study","volume":"30","author":"Drzezga","year":"2003","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"B10","doi-asserted-by":"publisher","first-page":"2173","DOI":"10.1161\/01.str.0000083699.95351.f2","article-title":"Randomized clinical trial of therapeutic exercise in subacute stroke","volume":"34","author":"Duncan","year":"2003","journal-title":"Stroke"},{"key":"B11","doi-asserted-by":"publisher","first-page":"271","DOI":"10.2307\/1165136","article-title":"Estimation of effect size from a series of independent experiments","volume":"18","author":"Gibbons","year":"1993","journal-title":"J. Educ. Stat."},{"key":"B12","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.clineuro.2014.08.017","article-title":"Pseudo-continuous arterial spin labeling quantifies cerebral blood flow in patients with acute ischemic stroke and chronic lacunar stroke","volume":"125","author":"Guo","year":"2014","journal-title":"Clin. Neurol. Neurosurg."},{"key":"B13","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1097\/00008483-200001000-00003","article-title":"The toronto cardiac rehabilitation and secondary prevention program: 1968 into the new millennium","volume":"20","author":"Hamm","year":"2000","journal-title":"J. Cardiopulm. Rehabil."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1994","DOI":"10.1161\/STROKEAHA.110.607879","article-title":"Improved cerebral vasomotor reactivity after exercise training in hemiparetic stroke survivors","volume":"42","author":"Ivey","year":"2011","journal-title":"Stroke"},{"key":"B15","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1258\/ar.2012.120450","article-title":"Arterial spin labeling in patients with chronic cerebral artery steno-occlusive disease: correlation with 15O-PET","volume":"54","author":"Kamano","year":"2013","journal-title":"Acta Radiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1002\/jmri.24246","article-title":"Reliability of two-dimensional and three-dimensional pseudo-continuous arterial spin labeling perfusion MRI in elderly populations: comparison with 15o-water positron emission tomography","volume":"39","author":"Kilroy","year":"2014","journal-title":"J. Magn. Reson. Imaging"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1892","DOI":"10.3174\/ajnr.A2008","article-title":"Multiple inflow pulsed arterial spin-labeling reveals delays in the arterial arrival time in minor stroke and transient ischemic attack","volume":"31","author":"MacIntosh","year":"2010","journal-title":"Am. J. Neuroradiol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1177\/1545968313496329","article-title":"Characteristics of exercise training interventions to improve cardiorespiratory fitness after stroke: a systematic review with meta-analysis","volume":"27","author":"Marsden","year":"2013","journal-title":"Neurorehabil. Neural Repair"},{"key":"B19","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1161\/STROKEAHA.111.635128","article-title":"The feasibility of cardiopulmonary exercise testing for prescribing exercise to people after stroke","volume":"43","author":"Marzolini","year":"2012","journal-title":"Stroke"},{"key":"B20","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1177\/1545968314562116","article-title":"Effects of community exercise therapy on metabolic, brain, physical, and cognitive function following stroke: a randomized controlled pilot trial","volume":"29","author":"Moore","year":"2015","journal-title":"Neurorehabil. Neural Repair"},{"key":"B21","doi-asserted-by":"publisher","first-page":"3184","DOI":"10.1177\/0271678x16683690","article-title":"The spatial coefficient of variation in arterial spin labeling cerebral blood flow images","volume":"37","author":"Mutsaerts","year":"2017","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"B22","doi-asserted-by":"publisher","first-page":"2467","DOI":"10.1007\/s00221-015-4317-6","article-title":"Exercise intensity modulates the change in cerebral blood flow following aerobic exercise in chronic stroke","volume":"233","author":"Robertson","year":"","journal-title":"Exp. Brain Res."},{"key":"B37","first-page":"11","article-title":"Aerobic exercise training increases frontal, parietal and occipital lobe cerebral blood flow in stroke survivors","volume":"10","author":"Robertson","year":"","journal-title":"Int. J. Stroke"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.3174\/ajnr.a5257","article-title":"Temporal and spatial variances in arterial spin-labeling are inversely related to large-artery blood velocity","volume":"38","author":"Robertson","year":"2017","journal-title":"Am. J. Neuroradiol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1159\/000366017","article-title":"The longitudinal evolution of cerebral blood flow regulation after acute ischaemic stroke","volume":"4","author":"Salinet","year":"2014","journal-title":"Cerebrovasc. Dis. Extra"},{"key":"B25","doi-asserted-by":"publisher","first-page":"e41","DOI":"10.1161\/STROKEAHA.109.559880","article-title":"Epidemiological studies of the effect of stroke on incident dementia: a systematic review","volume":"41","author":"Savva","year":"2010","journal-title":"Stroke"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1002\/jmri.24918","article-title":"Automated removal of spurious intermediate cerebral blood flow volumes improves image quality among older patients: a clinical arterial spin labeling investigation","volume":"42","author":"Shirzadi","year":"2015","journal-title":"J. Magn. Reson. Imaging"},{"key":"B27","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1007\/s11906-011-0195-x","article-title":"Vascular mechanisms in the pathogenesis of stroke","volume":"13","author":"Sierra","year":"2011","journal-title":"Curr. Hypertens. Rep."},{"key":"B28","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1002\/hbm.10062","article-title":"Fast robust automated brain extraction","volume":"17","author":"Smith","year":"2002","journal-title":"Hum. Brain Mapp."},{"key":"B29","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1111\/ijs.12156","article-title":"Exercise-induced changes in cardiovascular function after stroke: a randomized controlled trial","volume":"9","author":"Tang","year":"2014","journal-title":"Int. J. Stroke"},{"key":"B30","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1002\/jmri.24090","article-title":"Life-long aerobic exercise preserved baseline cerebral blood flow but reduced vascular reactivity to CO2","volume":"38","author":"Thomas","year":"2013","journal-title":"J. Magn. Reson. Imaging"},{"key":"B31","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1016\/j.neuroimage.2012.10.087","article-title":"Comparison of 2D and 3D single-shot ASL perfusion fMRI sequences","volume":"66","author":"Vidorreta","year":"2013","journal-title":"Neuroimage"},{"key":"B33","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.neulet.2013.12.011","article-title":"Cerebrovascular perfusion among older adults is moderated by strength training and gender","volume":"560","author":"Xu","year":"2014","journal-title":"Neurosci. Lett."},{"key":"B32","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1002\/jmri.24246","article-title":"Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3.0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimer\u2019s disease","volume":"23","author":"Xu","year":"2010","journal-title":"NMR Biomed."},{"key":"B34","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.nic.2011.01.003","article-title":"Arterial spin label imaging of acute ischemic stroke and transient ischemic attack","volume":"21","author":"Zaharchuk","year":"2011","journal-title":"Neuroimaging Clin. N. Am."},{"key":"B35","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1109\/42.906424","article-title":"Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm","volume":"20","author":"Zhang","year":"2001","journal-title":"IEEE Trans. Med. Imaging"},{"key":"B36","doi-asserted-by":"publisher","first-page":"2780","DOI":"10.1016\/j.jstrokecerebrovasdis.2016.07.035","article-title":"Aerobic exercises for cognition rehabilitation following stroke: a systematic review","volume":"25","author":"Zheng","year":"2016","journal-title":"J. Stroke Cerebrovasc. Dis."}],"container-title":["Frontiers in Aging Neuroscience"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fnagi.2017.00318\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,9,29]],"date-time":"2017-09-29T00:43:29Z","timestamp":1506645809000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fnagi.2017.00318\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,29]]},"references-count":37,"alternative-id":["10.3389\/fnagi.2017.00318"],"URL":"https:\/\/doi.org\/10.3389\/fnagi.2017.00318","relation":{},"ISSN":["1663-4365"],"issn-type":[{"value":"1663-4365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,29]]},"article-number":"318"}}