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Neurodegenerative diseases are a group of incurable neurological disorders of loss of neuron and\/or myelin sheath, which affect hundreds of millions of elderly populations and usually need long-term care. Older population is one of the most vulnerable to COVID-19 pandemic. In this report, we reviewed the current status of COVID-19 on the patients with several neurodegenerative diseases, particularly Alzheimer\u2019s disease, Parkinson\u2019s disease, prion disease, and amyotrophic lateral sclerosis. Meanwhile, the potential mechanisms of SARS-CoV-2 infection in the pathogenesis of neurodegenerative diseases were also summarized.<\/jats:p>","DOI":"10.3389\/fnagi.2021.664965","type":"journal-article","created":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T05:15:58Z","timestamp":1617858958000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":44,"title":["Impact of COVID-19 Pandemic on Patients With Neurodegenerative Diseases"],"prefix":"10.3389","volume":"13","author":[{"given":"Chao","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Ping","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,4,8]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare8030286","article-title":"Impact of COVID-19 on Alzheimer\u2019s disease risk: viewpoint for research action.","volume":"8","author":"Abate","year":"2020","journal-title":"Healthcare (Basel)"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1002\/mds.28118","article-title":"Can the 2019 novel coronavirus cause Parkinson\u2019s disease?","volume":"35","author":"Achbani","year":"2020","journal-title":"Mov. 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