{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:45:25Z","timestamp":1790394325701,"version":"4.1.0"},"reference-count":104,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T00:00:00Z","timestamp":1656028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Aging Neurosci."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Subjective cognitive decline (SCD) appears in the preclinical stage of the Alzheimer's disease continuum. In this stage, dynamic features are more sensitive than static features to reflect early subtle changes in functional brain connectivity. Therefore, we studied local and extended dynamic connectivity of the resting brain of people with SCD to determine their intrinsic brain changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We enrolled cognitively normal older adults from the communities and divided them into SCD and normal control (NC) groups. We used mean dynamic amplitude of low-frequency fluctuation (mdALFF) to evaluate region of interest (ROI)-wise local dynamic connectivity of resting-state functional MRI. The dynamic functional connectivity (dFC) between ROIs was tested by whole-brain-based statistics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      When comparing SCD (\n                      <jats:italic>N<\/jats:italic>\n                      = 40) with NC (\n                      <jats:italic>N<\/jats:italic>\n                      = 45), mdALFF\n                      <jats:sub>mean<\/jats:sub>\n                      decreased at right inferior parietal lobule (IPL) of the frontoparietal network (FPN). Still, it increased at the right middle temporal gyrus (MTG) of the ventral attention network (VAN) and right calcarine of the visual network (VIS). Also, the mdALFF\n                      <jats:sub>var<\/jats:sub>\n                      (variance) increased at the left superior temporal gyrus of AUD, right MTG of VAN, right globus pallidum of the cingulo-opercular network (CON), and right lingual gyrus of VIS. Furthermore, mdALFF\n                      <jats:sub>mean<\/jats:sub>\n                      at right IPL of FPN are correlated negatively with subjective complaints and positively with objective cognitive performance. In the dFC seeded from the ROIs with local mdALFF group differences, SCD showed a generally lower dFC\n                      <jats:sub>mean<\/jats:sub>\n                      and higher dFC\n                      <jats:sub>var<\/jats:sub>\n                      (variance) to other regions of the brain. These weakened and unstable functional connectivity appeared among FPN, CON, the default mode network, and the salience network, the large-scale networks of the triple network model for organizing neural resource allocations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The local dynamic connectivity of SCD decreased in brain regions of cognitive executive control. Meanwhile, compensatory visual efforts and bottom-up attention rose. Mixed decrease and compensatory increase of dynamics of intrinsic brain activity suggest the transitional nature of SCD. The FPN local dynamics balance subjective and objective cognition and maintain cognitive preservation in preclinical dementia. Aberrant triple network model features the dFC alternations of SCD. Finally, the right lateralization phenomenon emerged early in the dementia continuum and affected local dynamic connectivity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnagi.2022.817137","type":"journal-article","created":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T02:19:55Z","timestamp":1656037195000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":30,"title":["Functional Connectivity Dynamics Altered of the Resting Brain in Subjective Cognitive Decline"],"prefix":"10.3389","volume":"14","author":[{"given":"Yi-Chia","family":"Wei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Chia","family":"Kung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Yi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chemin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao-Liang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Ken","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chiau","family":"Shyu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Po","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,6,24]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J. Royal Stat. Soc. Ser. B. (Methodological)"},{"key":"B2","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/j.neuroimage.2012.01.090","article-title":"Resting state fMRI: a personal history","volume":"62","author":"Biswal","year":"2012","journal-title":"Neuroimage"},{"key":"B3","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/S0022-3999(01)00296-3","article-title":"The validity of the hospital anxiety and depression scale. an updated literature review","volume":"52","author":"Bjelland","year":"2002","journal-title":"J. Psychosom. Res"},{"key":"B4","doi-asserted-by":"publisher","first-page":"338r","DOI":"10.1126\/scitranslmed.aaf2362","article-title":"Tau and A\u03b2 imaging, CSF measures, and cognition in Alzheimer's disease","volume":"8","author":"Brier","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"B5","doi-asserted-by":"publisher","first-page":"2322","DOI":"10.1152\/jn.00339.2011","article-title":"The organization of the human cerebellum estimated by intrinsic functional connectivity","volume":"106","author":"Buckner","year":"2011","journal-title":"J. Neurophysiol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1037\/0882-7974.17.1.85","article-title":"Hemispheric asymmetry reduction in older adults: the HAROLD model","volume":"17","author":"Cabeza","year":"2002","journal-title":"Psychol. Aging"},{"key":"B7","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.jalz.2013.01.003","article-title":"Subjective cognitive decline: self and informant comparisons","volume":"10","author":"Caselli","year":"2014","journal-title":"Alzheimers. Dement"},{"key":"B8","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.neuroimage.2009.12.011","article-title":"Time-frequency dynamics of resting-state brain connectivity measured with fMRI","volume":"50","author":"Chang","year":"2010","journal-title":"Neuroimage"},{"key":"B9","doi-asserted-by":"publisher","first-page":"104051","DOI":"10.1016\/j.archger.2020.104051","article-title":"Physio-cognitive decline as the accelerated aging phenotype","author":"Chen","year":"2020","journal-title":"Arch. Gerontol. Geriatr"},{"key":"B10","doi-asserted-by":"publisher","first-page":"646017","DOI":"10.3389\/fnagi.2021.646017","article-title":"Alterations in dynamic functional connectivity in individuals with subjective cognitive decline","volume":"13","author":"Chen","year":"2021","journal-title":"Front. Aging. Neurosci"},{"key":"B11","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1089\/brain.2015.0357","article-title":"Lateral prefrontal cortex contributes to fluid intelligence through multinetwork connectivity","volume":"5","author":"Cole","year":"2015","journal-title":"Brain. Connect"},{"key":"B12","doi-asserted-by":"publisher","first-page":"1348","DOI":"10.1038\/nn.3470","article-title":"Multi-task connectivity reveals flexible hubs for adaptive task control","volume":"16","author":"Cole","year":"2013","journal-title":"Nat. Neurosci"},{"key":"B13","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1038\/nrn755","article-title":"Control of goal-directed and stimulus-driven attention in the brain","volume":"3","author":"Corbetta","year":"2002","journal-title":"Nat. Rev. Neurosci"},{"key":"B14","doi-asserted-by":"publisher","first-page":"40268","DOI":"10.1038\/srep40268","article-title":"Disrupted global metastability and static and dynamic brain connectivity across individuals in the Alzheimer's disease continuum","volume":"7","author":"Cordova-Palomera","year":"2017","journal-title":"Sci. Rep"},{"key":"B15","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1006\/cbmr.1996.0014","article-title":"AFNI: software for analysis and visualization of functional magnetic resonance neuroimages","volume":"29","author":"Cox","year":"1996","journal-title":"Comput. Biomed. Res"},{"key":"B16","doi-asserted-by":"publisher","first-page":"701","DOI":"10.3389\/fnins.2018.00701","article-title":"Integrating the local property and topological structure in the minimum spanning tree brain functional network for classification of early mild cognitive impairment","volume":"12","author":"Cui","year":"2018","journal-title":"Front. Neurosci"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1093\/cercor\/bhm155","article-title":"Que PASA? The posterior-anterior shift in aging","volume":"18","author":"Davis","year":"2008","journal-title":"Cereb. Cortex"},{"key":"B18","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.neuroimage.2017.11.025","article-title":"A comprehensive analysis of resting state fMRI measures to classify individual patients with Alzheimer's disease","volume":"167","author":"de Vos","year":"2018","journal-title":"Neuroimage"},{"key":"B19","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.nicl.2017.08.006","article-title":"A whole-brain computational modeling approach to explain the alterations in resting-state functional connectivity during progression of Alzheimer's disease","volume":"16","author":"Demirtas","year":"2017","journal-title":"Neuroimage. Clin"},{"key":"B20","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s11065-014-9249-6","article-title":"Functional brain connectivity using fMRI in aging and Alzheimer's disease","volume":"24","author":"Dennis","year":"2014","journal-title":"Neuropsychol. Rev"},{"key":"B21","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1016\/j.dadm.2018.08.011","article-title":"Altered functional connectivity strength in informant-reported subjective cognitive decline: a resting-state functional magnetic resonance imaging study","volume":"10","author":"Dong","year":"2018","journal-title":"Alzheimers. Dement. (Amst)"},{"key":"B22","doi-asserted-by":"publisher","first-page":"2692","DOI":"10.1007\/s11682-019-00220-6","article-title":"Dynamic network connectivity predicts subjective cognitive decline: the Sino-Longitudinal Cognitive impairment and dementia study","volume":"14","author":"Dong","year":"2020","journal-title":"Brain. Imaging. Behav"},{"key":"B23","doi-asserted-by":"publisher","first-page":"10046","DOI":"10.1073\/pnas.0604187103","article-title":"Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems","volume":"103","author":"Fox","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"B24","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1002\/hbm.20113","article-title":"Spontaneous low-frequency BOLD signal fluctuations: an fMRI investigation of the resting-state default mode of brain function hypothesis","volume":"26","author":"Fransson","year":"2005","journal-title":"Hum. Brain. Mapp"},{"key":"B25","doi-asserted-by":"publisher","first-page":"2836","DOI":"10.1016\/j.neuropsychologia.2006.06.017","article-title":"How default is the default mode of brain function? Further evidence from intrinsic BOLD signal fluctuations","volume":"44","author":"Fransson","year":"2006","journal-title":"Neuropsychologia"},{"key":"B26","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1038\/s41467-019-14159-1","article-title":"Functional brain architecture is associated with the rate of tau accumulation in Alzheimer's disease","volume":"11","author":"Franzmeier","year":"2020","journal-title":"Nat. Commun"},{"key":"B27","doi-asserted-by":"crossref","DOI":"10.1016\/B978-012372560-8\/50002-4","volume-title":"Statistical Parametric Mapping: The Analysis of Funtional Brain Images.","author":"Friston","year":"2007"},{"key":"B28","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1002\/mrm.1910350312","article-title":"Movement-Related effects in fMRI time-series","volume":"35","author":"Friston","year":"1996","journal-title":"Magnetic Resonance Med."},{"key":"B29","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1001\/archneur.64.5.725","article-title":"Patient's Rating of Cognitive Ability: Using the AD8, a Brief Informant Interview, as a Self-rating Tool to Detect Dementia","volume":"64","author":"Galvin","year":"2007","journal-title":"JAMA Neurol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1212\/01.wnl.0000172958.95282.2a","article-title":"The AD8: a brief informant interview to detect dementia","volume":"65","author":"Galvin","year":"2005","journal-title":"Neurology"},{"key":"B31","doi-asserted-by":"publisher","first-page":"1942","DOI":"10.1212\/01.wnl.0000247042.15547.eb","article-title":"Validity and reliability of the AD8 informant interview in dementia","volume":"67","author":"Galvin","year":"2006","journal-title":"Neurology"},{"key":"B32","doi-asserted-by":"publisher","first-page":"15","DOI":"10.3233\/JAD-2010-101674","article-title":"Homeostatic disinhibition in the aging brain and Alzheimer's disease","volume":"24","author":"Gleichmann","year":"2011","journal-title":"J. Alzheimers Dis"},{"key":"B33","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1093\/brain\/awu337","article-title":"Auditory spatial processing in Alzheimer's disease","volume":"138","author":"Golden","year":"2015","journal-title":"Brain"},{"key":"B34","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1038\/nrn3256","article-title":"The cognitive neuroscience of ageing","volume":"13","author":"Grady","year":"2012","journal-title":"Nat. Rev. Neurosci"},{"key":"B35","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1111\/psyp.13032","article-title":"Control networks and hubs","author":"Gratton","year":"2018","journal-title":"Psychophysiology"},{"key":"B36","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1111\/cns.13387","article-title":"Abnormal dynamic functional connectivity in Alzheimer's disease","volume":"26","author":"Gu","year":"2020","journal-title":"CNS. Neurosci. Ther"},{"key":"B37","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1089\/brain.2013.0144","article-title":"Increased functional connectivity and brain atrophy in elderly with subjective memory complaints","volume":"3","author":"Hafkemeijer","year":"2013","journal-title":"Brain. Connect"},{"key":"B38","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1001\/jamaneurol.2019.1424","article-title":"Association of amyloid and tau with cognition in preclinical Alzheimer disease: a longitudinal study","volume":"76","author":"Hanseeuw","year":"2019","journal-title":"JAMA Neurol"},{"key":"B39","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1016\/j.neuroimage.2006.11.042","article-title":"Regional coherence changes in the early stages of Alzheimer's disease: a combined structural and resting-state functional MRI study","volume":"35","author":"He","year":"2007","journal-title":"Neuroimage"},{"key":"B40","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.neuroimage.2013.05.079","article-title":"Dynamic functional connectivity: promise, issues, and interpretations","volume":"80","author":"Hutchison","year":"2013","journal-title":"Neuroimage"},{"key":"B41","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S1474-4422(09)70299-6","article-title":"Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade","volume":"9","author":"Jack","year":"2010","journal-title":"Lancet Neurology"},{"key":"B42","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/j.jalz.2014.01.001","article-title":"A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease","volume":"10","author":"Jessen","year":"2014","journal-title":"Alzheimers Dement"},{"key":"B43","doi-asserted-by":"publisher","first-page":"566","DOI":"10.3389\/fneur.2019.00566","article-title":"Frequency-dependent relationship between resting-state fmri and glucose metabolism in the elderly","volume":"10","author":"Jiao","year":"2019","journal-title":"Front. Neurol"},{"key":"B44","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.media.2018.03.013","article-title":"Integration of temporal and spatial properties of dynamic connectivity networks for automatic diagnosis of brain disease","volume":"47","author":"Jie","year":"2018","journal-title":"Med. Image. Anal"},{"key":"B45","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1093\/brain\/awaa429","article-title":"Hearing and dementia: from ears to brain","volume":"144","author":"Johnson","year":"2021","journal-title":"Brain"},{"key":"B46","doi-asserted-by":"publisher","first-page":"e39731","DOI":"10.1371\/journal.pone.0039731","article-title":"Non-stationarity in the resting brain's modular architecture","volume":"7","author":"Jones","year":"2012","journal-title":"PLoS ONE."},{"key":"B47","doi-asserted-by":"publisher","first-page":"613","DOI":"10.3389\/fpsyg.2015.00613","article-title":"Dynamics of auditory working memory","volume":"6","author":"Kaiser","year":"2015","journal-title":"Front. Psychol"},{"key":"B48","doi-asserted-by":"publisher","first-page":"101675","DOI":"10.1016\/j.nicl.2019.101675","article-title":"Subjective memory complaints are associated with altered resting-state functional connectivity but not structural atrophy","volume":"21","author":"Kawagoe","year":"2019","journal-title":"Neuroimage. Clin"},{"key":"B49","doi-asserted-by":"publisher","first-page":"3192","DOI":"10.1002\/hbm.24590","article-title":"Instability of brain connectivity during nonrapid eye movement sleep reflects altered properties of information integration","volume":"40","author":"Kung","year":"2019","journal-title":"Hum. Brain. Mapp"},{"key":"B50","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1002\/hbm.20600","article-title":"Endogenous brain oscillations and related networks detected by surface EEG-combined fMRI","volume":"29","author":"Laufs","year":"2008","journal-title":"Hum. Brain. Mapp"},{"key":"B51","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/S0924-9338(97)83296-8","article-title":"The Mini International Neuropsychiatric Interview (MINI). A short diagnostic structured interview: reliability and validity according to the CIDI","volume":"12","author":"Lecrubier","year":"1997","journal-title":"European. Psychiatry"},{"key":"B52","doi-asserted-by":"publisher","first-page":"16610","DOI":"10.1038\/s41598-017-16789-1","article-title":"Linking functional connectivity and dynamic properties of resting-state networks","volume":"7","author":"Lee","year":"2017","journal-title":"Sci. Rep"},{"key":"B53","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.neuroimage.2014.09.007","article-title":"On spurious and real fluctuations of dynamic functional connectivity during rest","volume":"104","author":"Leonardi","year":"2015","journal-title":"Neuroimage"},{"key":"B54","doi-asserted-by":"publisher","first-page":"237","DOI":"10.3233\/JAD-181097","article-title":"Abnormal brain network connectivity in a triple-network model of Alzheimer's Disease","volume":"69","author":"Li","year":"2019","journal-title":"J. Alzheimers. Dis"},{"key":"B55","first-page":"103","article-title":"Cross-level unification: A computational exploration of the link between deterioration of neurotransmitter systems and dedifferentiation of cognitive abilities in old age","volume-title":"Cognitive Neuroscience of Memory","author":"Li","year":"1999"},{"key":"B56","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/S1364-6613(00)01769-1","article-title":"Aging cognition: from neuromodulation to representation","volume":"5","author":"Li","year":"2001","journal-title":"Trends. Cogn. Sci"},{"key":"B57","doi-asserted-by":"publisher","first-page":"2523","DOI":"10.1109\/TMI.2019.2904555","article-title":"Endless fluctuations: temporal dynamics of the amplitude of low frequency fluctuations","volume":"38","author":"Liao","year":"2019","journal-title":"IEEE Transac. Med. Imag."},{"key":"B58","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1089\/brain.2014.0253","article-title":"DynamicBC: a MATLAB toolbox for dynamic brain connectome analysis","volume":"4","author":"Liao","year":"2014","journal-title":"Brain. Connect"},{"key":"B59","doi-asserted-by":"publisher","first-page":"3","DOI":"10.3389\/fneur.2018.00003","article-title":"Changes in brain lateralization in patients with mild cognitive impairment and alzheimer's disease: a resting-state functional magnetic resonance study from Alzheimer's disease neuroimaging initiative","volume":"9","author":"Liu","year":"2018","journal-title":"Front. Neurol"},{"key":"B60","doi-asserted-by":"publisher","first-page":"1422","DOI":"10.1093\/cercor\/bhs410","article-title":"Impaired long distance functional connectivity and weighted network architecture in Alzheimer's disease","volume":"24","author":"Liu","year":"2014","journal-title":"Cereb. Cortex"},{"key":"B61","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.neurobiolaging.2016.06.011","article-title":"Discrepancies between fluid and crystallized ability in healthy adults: a behavioral marker of preclinical Alzheimer's disease","volume":"46","author":"Mcdonough","year":"2016","journal-title":"Neurobiol. Aging"},{"key":"B62","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.jalz.2011.03.005","article-title":"The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease","volume":"7","author":"Mckhann","year":"2011","journal-title":"Alzheimers. Dement"},{"key":"B63","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.tics.2011.08.003","article-title":"Large-scale brain networks and psychopathology: a unifying triple network model","volume":"15","author":"Menon","year":"2011","journal-title":"Trends. Cogn. Sci"},{"key":"B64","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.jalz.2016.09.012","article-title":"Implementation of subjective cognitive decline criteria in research studies","volume":"13","author":"Molinuevo","year":"2017","journal-title":"Alzheimers Dement"},{"key":"B65","doi-asserted-by":"publisher","first-page":"101848","DOI":"10.1016\/j.nicl.2019.101848","article-title":"Tau covariance patterns in Alzheimer's disease patients match intrinsic connectivity networks in the healthy brain","volume":"23","author":"Ossenkoppele","year":"2019","journal-title":"Neuroimage. Clin"},{"key":"B66","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/j.neuroimage.2013.02.035","article-title":"Infraslow LFP correlates to resting-state fMRI BOLD signals","volume":"74","author":"Pan","year":"2013","journal-title":"Neuroimage"},{"key":"B67","doi-asserted-by":"publisher","first-page":"109","DOI":"10.31887\/DCNS.2013.15.1\/dpark","article-title":"The aging mind: neuroplasticity in response to cognitive training","volume":"15","author":"Park","year":"2013","journal-title":"Dialogues. Clin. Neurosci"},{"key":"B68","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1146\/annurev.psych.59.103006.093656","article-title":"The adaptive brain: aging and neurocognitive scaffolding","volume":"60","author":"Park","year":"2009","journal-title":"Annu. Rev. Psychol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.3233\/JAD-200299","article-title":"Identification of earlier biomarkers for alzheimer's disease: a multimodal neuroimaging study of individuals with subjective cognitive decline","volume":"77","author":"Parker","year":"2020","journal-title":"J. Alzheimers Dis"},{"key":"B70","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1001\/archneur.56.3.303","article-title":"Mild cognitive impairment: clinical characterization and outcome","volume":"56","author":"Petersen","year":"1999","journal-title":"Arch. Neurol"},{"key":"B71","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/j.neuron.2011.09.006","article-title":"Functional network organization of the human brain","volume":"72","author":"Power","year":"2011","journal-title":"Neuron"},{"key":"B72","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.neuroimage.2016.12.061","article-title":"The dynamic functional connectome: State-of-the-art and perspectives","volume":"160","author":"Preti","year":"2017","journal-title":"Neuroimage"},{"key":"B73","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1007\/s11682-014-9336-6","article-title":"Functional-structural degeneration in dorsal and ventral attention systems for Alzheimer's disease, amnestic mild cognitive impairment","volume":"9","author":"Qian","year":"2015","journal-title":"Brain Imag. Behav."},{"key":"B74","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1212\/WNL.0b013e318230208a","article-title":"Normative data for the Montreal Cognitive Assessment (MoCA) in a population-based sample","volume":"77","author":"Rossetti","year":"2011","journal-title":"Neurology"},{"key":"B75","doi-asserted-by":"publisher","first-page":"116290","DOI":"10.1016\/j.neuroimage.2019.116290","article-title":"A set of functionally-defined brain regions with improved representation of the subcortex and cerebellum","volume":"206","author":"Seitzman","year":"2020","journal-title":"Neuroimage"},{"key":"B76","first-page":"676","article-title":"Factor structure and explanatory variables of the Mini-Mental State Examination (MMSE) for elderly persons in Taiwan","volume":"100","author":"Shyu","year":"2001","journal-title":"J. Formos. Med. Assoc"},{"key":"B77","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1212\/WNL.43.4.779","article-title":"Auditory system degeneration in Alzheimer's disease","volume":"43","author":"Sinha","year":"1993","journal-title":"Neurology"},{"key":"B78","doi-asserted-by":"publisher","first-page":"S208","DOI":"10.1016\/j.neuroimage.2004.07.051","article-title":"Advances in functional and structural MR image analysis and implementation as FSL","volume":"23","author":"Smith","year":"2004","journal-title":"NeuroImage"},{"key":"B79","doi-asserted-by":"publisher","first-page":"18760","DOI":"10.1073\/pnas.0708803104","article-title":"Selective changes of resting-state networks in individuals at risk for Alzheimer's disease","volume":"104","author":"Sorg","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"B80","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.jalz.2011.03.003","article-title":"Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease","volume":"7","author":"Sperling","year":"2011","journal-title":"Alzheimers. Dement"},{"key":"B81","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1148\/radiol.2016151771","article-title":"Subjective cognitive decline: mapping functional and structural brain changes-a combined resting-state functional and structural MR imaging study","volume":"281","author":"Sun","year":"2016","journal-title":"Radiology"},{"key":"B82","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1006\/nimg.2001.0978","article-title":"Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain","volume":"15","author":"Tzourio-Mazoyer","year":"2002","journal-title":"NeuroImage"},{"key":"B83","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/nrn3857","article-title":"Salience processing and insular cortical function and dysfunction","volume":"16","author":"Uddin","year":"2015","journal-title":"Nat. Rev. Neurosci"},{"key":"B84","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s13195-020-00591-9","article-title":"Functional neuroimaging in subjective cognitive decline: current status and a research path forward","volume":"12","author":"Viviano","year":"2020","journal-title":"Alzheimers. Res. Ther"},{"key":"B85","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/s13024-020-00395-3","article-title":"Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease","volume":"15","author":"Wang","year":"2020","journal-title":"Mol. Neurodegener"},{"key":"B86","doi-asserted-by":"publisher","first-page":"26","DOI":"10.3389\/fninf.2019.00026","article-title":"Functional connectivity changes across the spectrum of subjective cognitive decline, amnestic mild cognitive impairment and Alzheimer's disease","volume":"13","author":"Wang","year":"2019","journal-title":"Front. Neuroinform"},{"key":"B87","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1007\/s11682-015-9408-2","article-title":"Sparse temporally dynamic resting-state functional connectivity networks for early MCI identification","volume":"10","author":"Wee","year":"2016","journal-title":"Brain. Imaging. Behav"},{"key":"B88","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1159\/000497222","article-title":"Subjective cognitive decline in the community is affected at multiple aspects of mental health and life quality: a cross-sectional study of the community medicine of Keelung Chang Gung Memorial Hospital","volume":"9","author":"Wei","year":"2019","journal-title":"Dement. Geriatr. Cogn. Dis. Extra"},{"key":"B89","doi-asserted-by":"publisher","first-page":"747","DOI":"10.2147\/NDT.S298233","article-title":"Taiwanese Depression Questionnaire and AD8 Questionnaire for Screening Late-Life Depression in Communities","volume":"17","author":"Wei","year":"2021","journal-title":"Neuropsychiatric Dis. Treat."},{"key":"B90","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.nicl.2018.07.016","article-title":"Left lateralized cerebral glucose metabolism declines in amyloid-beta positive persons with mild cognitive impairment","volume":"20","author":"Weise","year":"2018","journal-title":"Neuroimage. Clin"},{"key":"B91","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1111\/j.1365-2796.2004.01380.x","article-title":"Mild cognitive impairment\u2014beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment","volume":"256","author":"Winblad","year":"2004","journal-title":"J. Intern. Med"},{"key":"B92","doi-asserted-by":"publisher","first-page":"118","DOI":"10.3389\/fnagi.2019.00118","article-title":"Changes in centrality frequency of the default mode network in individuals with subjective cognitive decline","volume":"11","author":"Xie","year":"2019","journal-title":"Front Aging Neurosci"},{"key":"B93","doi-asserted-by":"publisher","first-page":"711009","DOI":"10.3389\/fnagi.2021.711009","article-title":"Disrupted dynamic functional connectivity in distinguishing subjective cognitive decline and amnestic mild cognitive impairment based on the triple-network model","volume":"13","author":"Xue","year":"2021","journal-title":"Front. Aging. Neurosci"},{"key":"B94","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1016\/j.scib.2017.09.015","article-title":"Concordance among indices of intrinsic brain function: insights from inter-individual variation and temporal dynamics","volume":"62","author":"Yan","year":"2017","journal-title":"Science. Bull."},{"key":"B95","doi-asserted-by":"publisher","first-page":"975","DOI":"10.3389\/fnins.2018.00975","article-title":"Gradual Disturbances of the Amplitude of Low-Frequency Fluctuations (ALFF) and Fractional ALFF in Alzheimer Spectrum","volume":"12","author":"Yang","year":"2018","journal-title":"Front. Neurosci"},{"key":"B96","doi-asserted-by":"publisher","first-page":"584863","DOI":"10.3389\/fnagi.2020.584863","article-title":"Dynamics and concordance abnormalities among indices of intrinsic brain activity in individuals with subjective cognitive decline: a temporal dynamics resting-state functional magnetic resonance imaging analysis","volume":"12","author":"Yang","year":"2020","journal-title":"Front. Aging. Neurosci"},{"key":"B97","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1177\/1533317510397330","article-title":"Application of AD8 questionnaire to screen very mild dementia in Taiwanese","volume":"26","author":"Yang","year":"2011","journal-title":"Am. J. Alzheimers Dis. Other. Demen"},{"key":"B98","doi-asserted-by":"publisher","first-page":"1197","DOI":"10.1016\/j.neuroimage.2010.06.041","article-title":"Network-based statistic: identifying differences in brain networks","volume":"53","author":"Zalesky","year":"2010","journal-title":"Neuroimage"},{"key":"B99","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1159\/000486152","article-title":"Decreased fronto-parietal and increased default mode network activation is associated with subtle cognitive deficits in elderly controls","volume":"25","author":"Zanchi","year":"2017","journal-title":"Neurosignals"},{"key":"B100","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.braindev.2006.07.002","article-title":"Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI","volume":"29","author":"Zang","year":"2007","journal-title":"Brain. Dev"},{"key":"B101","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1016\/j.tics.2013.10.001","article-title":"Fronto-parietal network: flexible hub of cognitive control","volume":"17","author":"Zanto","year":"2013","journal-title":"Trends. Cogn. Sci"},{"key":"B102","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1038\/nrneurol.2009.198","article-title":"Disease and the brain's dark energy","volume":"6","author":"Zhang","year":"2010","journal-title":"Nat. Rev. Neurol"},{"key":"B103","doi-asserted-by":"publisher","first-page":"3665","DOI":"10.1007\/s00429-017-1425-z","article-title":"A posterior-to-anterior shift of brain functional dynamics in aging","volume":"222","author":"Zhang","year":"2017","journal-title":"Brain. Struct. Funct"},{"key":"B104","doi-asserted-by":"publisher","first-page":"103","DOI":"10.3233\/THC-174235","article-title":"Study of altered functional connectivity in individuals at risk for Alzheimer's Disease","volume":"26","author":"Zhang","year":"2018","journal-title":"Technol. Health. Care"}],"container-title":["Frontiers in Aging Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnagi.2022.817137\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T02:19:58Z","timestamp":1656037198000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnagi.2022.817137\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,24]]},"references-count":104,"alternative-id":["10.3389\/fnagi.2022.817137"],"URL":"https:\/\/doi.org\/10.3389\/fnagi.2022.817137","relation":{},"ISSN":["1663-4365"],"issn-type":[{"value":"1663-4365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,24]]},"article-number":"817137"}}