{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T04:57:44Z","timestamp":1788411464085,"version":"build-2803163510"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of Hunan Province","doi-asserted-by":"publisher","award":["2023JJ60458"],"award-info":[{"award-number":["2023JJ60458"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of Hunan Province","doi-asserted-by":"publisher","award":["2023JJ30367"],"award-info":[{"award-number":["2023JJ30367"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Aging Neurosci."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Parkinson\u2019s disease (PD) is a neurodegenerative disorder that predominantly affects the elderly. Evidence indicates that microglia-mediated neuroinflammation is recognized as one of the key mechanisms in PD. This study aims to analyze the key points, hotspots, and emerging frontiers in research related to PD and microglia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Publications were obtained from the Web of Science and PubMed databases. VOSviewer and CiteSpace were used to generate visual representations and conduct numerical analyses of the dataset.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>China and the United States were the leading contributors. Shanghai Jiao Tong University was the most active institution. The <jats:italic>Journal of Neuroinflammation<\/jats:italic> published the most papers on microglia and PD. Dr. Jau-Shyong Hong was the most prolific author. High-frequency keywords included PD, microglia, neuroinflammation, alpha-synuclein (a-syn), neurodegeneration, microglial activation, and oxidative stress. Gut microbiota and the NLRP3 inflammasome have garnered significant interest from researchers in recent years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study generated visual mappings of microglia and PD-related research. Neuroinflammation, a-syn, neurodegeneration, microglial activation, and oxidative stress represent major focuses and hotspots in this field. Gut microbiota and the NLRP3 inflammasome have rapidly attracted research attention and are likely to be key directions for future studies in the coming years.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fnagi.2025.1657349","type":"journal-article","created":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T05:35:37Z","timestamp":1758000937000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Microglia-associated research in Parkinson\u2019s disease: a bibliometric analysis"],"prefix":"10.3389","volume":"17","author":[{"given":"Yan-Jun","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Rong","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Qiang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1007\/s13311-020-00889-4","article-title":"Medical management and prevention of motor complications in Parkinson's disease","volume":"17","author":"Aradi","year":"2020","journal-title":"Neurotherapeutics"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"106091","DOI":"10.1016\/j.neubiorev.2025.106091","article-title":"Morphological diversity of microglia: implications for learning, environmental adaptation, ageing, sex differences and neuropathology","volume":"172","author":"Augusto-Oliveira","year":"2025","journal-title":"Neurosci. 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