{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T16:13:09Z","timestamp":1793722389325,"version":"4.6.1"},"reference-count":526,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006013","name":"United Arab Emirates University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006013","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Aging Neurosci."],"abstract":"<jats:p>The microbiota\u2013gut\u2013brain axis (MGBA) is increasingly recognized as a critical regulator of brain health, influencing both neurodevelopment and age-related neurological decline. Disruptions in this axis, driven by gut dysbiosis, have been implicated in the pathogenesis of a wide range of neurodegenerative and neuropsychiatric disorders. This review synthesizes current evidence linking microbiota alterations to Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and stroke\u2014including post-stroke cognitive impairment (PSCI), as well as major depressive disorder (MDD), bipolar disorder (BD), anxiety disorders, post-traumatic stress disorder (PTSD), and chronic fatigue syndrome (CFS). Common findings include reduced microbial diversity, depletion of short-chain fatty acid (SCFA)-producing genera, and enrichment of pro-inflammatory taxa. These changes contribute to neuroinflammation, blood\u2013brain barrier (BBB) dysfunction, microglial activation, and neurotransmitter imbalances. The review further explores the neurotoxic effects of external factors such as radiation and xenobiotics on the MGBA. Despite disorder-specific variations, shared microbial and immunological mechanisms emerge across the spectrum of conditions. Importantly, we present current and emerging strategies aimed at restoring gut\u2013brain communication, including dietary interventions such as fiber-rich and Mediterranean diets, SCFA supplementation, probiotics, and fecal microbiota transplantation (FMT). These approaches show promise in alleviating cognitive and emotional symptoms, modulating immune responses, and potentially slowing disease progression. By integrating mechanistic insights with therapeutic perspectives, this review underscores the gut microbiota as a modifiable factor in neuropsychiatric and neurodegenerative disease. Targeting the MGBA offers a novel, translational approach to intervention that may ultimately contribute to healthier brain aging and improved outcomes across the lifespan.<\/jats:p>","DOI":"10.3389\/fnagi.2025.1667448","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T05:52:27Z","timestamp":1759297947000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":42,"title":["The microbiota\u2013gut\u2013brain axis in mental and neurodegenerative disorders: opportunities for prevention and intervention"],"prefix":"10.3389","volume":"17","author":[{"given":"Lidya K.","family":"Yassin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jurga","family":"Skrabulyte-Barbulescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shamsa H.","family":"Alshamsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Saeed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shamma H.","family":"Alkuwaiti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saif","family":"Almazrouei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abeer","family":"Alnuaimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shamsa","family":"BaniYas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Aldhaheri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahra","family":"Alderei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safa","family":"Shehab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad I. K.","family":"Hamad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,10,1]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1017\/neu.2017.3","article-title":"Gut\u2013brain actions underlying comorbid anxiety and depression associated with inflammatory bowel disease","volume":"30","author":"Abautret-Daly","year":"2018","journal-title":"Acta Neuropsychiatr."},{"key":"B2","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.resmic.2015.09.006","article-title":"Diet drives quick changes in the metabolic activity and composition of human gut microbiota in a validated in vitro gut model","volume":"167","author":"Aguirre","year":"2016","journal-title":"Res. Microbiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"117377","DOI":"10.1016\/j.biopha.2024.117377","article-title":"Christensenella minuta mitigates behavioral and cardiometabolic hallmarks of social defeat stress","volume":"180","author":"Agusti","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"B4","doi-asserted-by":"publisher","first-page":"82.e5","DOI":"10.1016\/j.genhosppsych.2010.07.002","article-title":"A man who wanted to commit suicide by hanging himself: an adverse effect of ciprofloxacin","volume":"33","author":"Ahmed","year":"2011","journal-title":"General Hosp. Psychiatry"},{"key":"B5","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1016\/j.ebiom.2019.05.064","article-title":"Gut microbiota in Parkinson?s disease: temporal stability and relations to disease progression","volume":"44","author":"Aho","year":"2019","journal-title":"eBioMedicine"},{"key":"B6","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.ntt.2018.04.002","article-title":"Glyphosate based- herbicide exposure affects gut microbiota, anxiety and depression-like behaviors in mice","volume":"67","author":"Aitbali","year":"2018","journal-title":"Neurotoxicol. Teratol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"730","DOI":"10.3389\/fpsyt.2018.00730","article-title":"Bifidobacterium and Lactobacillus counts in the gut microbiota of patients with bipolar disorder and healthy controls","volume":"9","author":"Aizawa","year":"2019","journal-title":"Front. Psychiatry"},{"key":"B8","doi-asserted-by":"publisher","first-page":"5238","DOI":"10.3390\/ijms24065238","article-title":"To predict, prevent, and manage post-traumatic stress disorder (PTSD): a review of pathophysiology, treatment, and biomarkers","volume":"24","author":"Al Jowf","year":"2023","journal-title":"IJMS"},{"key":"B9","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1038\/nrneurol.2013.203","article-title":"The epidemiology of ALS: a conspiracy of genes, environment and time","volume":"9","author":"Al-Chalabi","year":"2013","journal-title":"Nat. Rev. Neurol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1187758","DOI":"10.3389\/fnins.2023.1187758","article-title":"The long-term effects of maternal deprivation on the number and size of inhibitory interneurons in the rat amygdala and nucleus accumbens","volume":"17","author":"Aleksic","year":"2023","journal-title":"Front. Neurosci."},{"key":"B11","doi-asserted-by":"publisher","first-page":"2951","DOI":"10.3390\/jcm9092951","article-title":"Neurophysiology and psychopathology underlying PTSD and recent insights into the PTSD therapies\u2014a comprehensive review","volume":"9","author":"Aliev","year":"2020","journal-title":"JCM"},{"key":"B12","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.gie.2017.05.036","article-title":"The 5D framework: a clinical primer for fecal microbiota transplantation to treat Clostridium difficile infection","volume":"87","author":"Allegretti","year":"2018","journal-title":"Gastrointest. Endosc."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.1038\/mp.2010.101","article-title":"Days out of role due to common physical and mental conditions: results from the WHO World Mental Health surveys","volume":"16","author":"Alonso","year":"2011","journal-title":"Mol. Psychiatry"},{"key":"B14","doi-asserted-by":"publisher","first-page":"e725","DOI":"10.1002\/osp4.725","article-title":"Mediterranean diet intervention among World Trade Center responders with post-traumatic stress disorder: feasibility and outcomes of a pilot randomized controlled trial","volume":"10","author":"Arcan","year":"2024","journal-title":"Obes. Sci. Pract."},{"key":"B15","doi-asserted-by":"publisher","first-page":"43390","DOI":"10.4088\/JCP.21r14328","article-title":"Impact of major depressive disorder on comorbidities: a systematic literature review","volume":"83","author":"Arnaud","year":"2022","journal-title":"J. Clin. Psychiatry"},{"key":"B16","doi-asserted-by":"publisher","first-page":"5587","DOI":"10.3390\/ijms25115587","article-title":"Revisiting glutamate excitotoxicity in amyotrophic lateral sclerosis and age-related neurodegeneration","volume":"25","author":"Arnold","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"B17","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1038\/nrneurol.2017.185","article-title":"Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums","volume":"14","author":"Arnold","year":"2018","journal-title":"Nat. Rev. Neurol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1002\/alz.12084","article-title":"The biogenesis and biology of amyloid \u03b2 oligomers in the brain","volume":"16","author":"Ashe","year":"2020","journal-title":"Alzheimer. Dementia"},{"key":"B19","doi-asserted-by":"publisher","first-page":"120861","DOI":"10.1016\/j.lfs.2022.120861","article-title":"Alzheimer's disease failed clinical trials","volume":"306","author":"Asher","year":"2022","journal-title":"Life Sci."},{"key":"B20","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1126\/science.1198469","article-title":"Induction of colonic regulatory T cells by indigenous Clostridium species","volume":"331","author":"Atarashi","year":"2011","journal-title":"Science"},{"key":"B21","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1016\/j.ebiom.2015.10.018","article-title":"Risperidone-induced weight gain is mediated through shifts in the gut microbiome and suppression of energy expenditure","volume":"2","author":"Bahr","year":"2015","journal-title":"EBioMedicine"},{"key":"B22","doi-asserted-by":"publisher","first-page":"745262","DOI":"10.3389\/fonc.2021.745262","article-title":"Gut microbiome and its associations with acute and chronic gastrointestinal toxicities in cancer patients with pelvic radiation therapy: a systematic review","volume":"11","author":"Bai","year":"2021","journal-title":"Front. Oncol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"G661","DOI":"10.1152\/ajpgi.00194.2019","article-title":"Posttraumatic stress disorder is associated with altered gut microbiota that modulates cognitive performance in veterans with cirrhosis","volume":"317","author":"Bajaj","year":"2019","journal-title":"Am. J. Physiol. Gastrointestinal Liver Physiol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1186\/s12915-020-00775-7","article-title":"Parkinson's disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions","volume":"18","author":"Baldini","year":"2020","journal-title":"BMC Biol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1007\/s10787-017-0311-x","article-title":"A combination of probiotics and magnesium orotate attenuate depression in a small SSRI resistant cohort: an intestinal anti-inflammatory response is suggested","volume":"25","author":"Bambling","year":"2017","journal-title":"Inflammopharmacology"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1896","DOI":"10.3390\/ijms26051896","article-title":"Cognitive dysfunction in myalgic encephalomyelitis\/chronic fatigue syndrome-aetiology and potential treatments","volume":"26","author":"Bansal","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"B27","doi-asserted-by":"publisher","first-page":"541","DOI":"10.3389\/fpsyt.2020.00541","article-title":"Altered composition of gut microbiota in depression: a systematic review","volume":"11","author":"Barandouzi","year":"2020","journal-title":"Front. Psychiatry"},{"key":"B28","doi-asserted-by":"publisher","first-page":"103408","DOI":"10.1016\/j.autrev.2023.103408","article-title":"Intermittent fasting: a promising dietary intervention for autoimmune diseases","volume":"22","author":"Barati","year":"2023","journal-title":"Autoimmun. Rev."},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1101\/2024.08.27.609990","article-title":"Prenatal exposure to dietary levels of glyphosate disrupts metabolic, immune, and behavioral markers across generations in mice","author":"Barnett","year":"2024","journal-title":"bioRxiv"},{"key":"B30","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1111\/lam.12882","article-title":"Shifts in gut microbiota composition in an APP\/PSS1 transgenic mouse model of Alzheimer's disease during lifespan","volume":"66","author":"B\u00e4uerl","year":"2018","journal-title":"Lett. Appl. Microbiol."},{"key":"B31","volume-title":"Cognitive-Communication Disorders of MCI and Dementia: Definition, Assessment, and Clinical Management, 3rd Edn","author":"Bayles","year":"2018"},{"key":"B32","doi-asserted-by":"publisher","first-page":"261","DOI":"10.2174\/1567205016666190301111120","article-title":"Pharmacological interventions to attenuate Alzheimer's disease progression: the story so far","volume":"16","author":"Bazzari","year":"2019","journal-title":"CAR"},{"key":"B33","doi-asserted-by":"publisher","first-page":"723","DOI":"10.3390\/microorganisms9040723","article-title":"The microbiome-gut-brain axis and resilience to developing anxiety or depression under stress","volume":"9","author":"Bear","year":"2021","journal-title":"Microorganisms"},{"key":"B34","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/j.gpb.2021.08.009","article-title":"Effects of resistant starch on symptoms, fecal markers, and gut microbiota in Parkinson's disease \u2014 the RESISTA-PD trial","volume":"20","author":"Becker","year":"2022","journal-title":"Genom. Proteomics Bioinformat."},{"key":"B35","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1186\/s13073-017-0451-z","article-title":"Erratum to: Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-na\u00efve Parkinson's disease patients","volume":"9","author":"Bedarf","year":"2017","journal-title":"Genome Med."},{"key":"B36","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1038\/nm.4068","article-title":"Commensal microbiota affects ischemic stroke outcome by regulating intestinal \u03b3\u03b4 T cells","volume":"22","author":"Benakis","year":"2016","journal-title":"Nat. Med."},{"key":"B37","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1038\/s41380-022-01842-x","article-title":"Longitudinal volumetric evaluation of hippocampus and amygdala subregions in recent trauma survivors","volume":"28","author":"Ben-Zion","year":"2023","journal-title":"Mol. Psychiatry"},{"key":"B38","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1053\/j.gastro.2011.04.052","article-title":"The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice","volume":"141","author":"Bercik","year":"2011","journal-title":"Gastroenterology"},{"key":"B39","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.neulet.2009.02.041","article-title":"Production of panic-like symptoms by lactate is associated with increased neural firing and oxidation of brain redox in the rat hippocampus","volume":"453","author":"Bergold","year":"2009","journal-title":"Neurosci. Lett."},{"key":"B40","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s12916-016-0771-7","article-title":"Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress","volume":"15","author":"Bharwani","year":"2017","journal-title":"BMC Med."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1478304","DOI":"10.3389\/fnins.2025.1478304","article-title":"Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics","volume":"19","author":"Bibi","year":"2025","journal-title":"Front. Neurosci."},{"key":"B42","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1038\/nrn4019","article-title":"Hippocampal insulin resistance and cognitive dysfunction","volume":"16","author":"Biessels","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"B43","doi-asserted-by":"publisher","first-page":"e229817","DOI":"10.1001\/jamanetworkopen.2022.9817","article-title":"Association of depression and anxiety with the accumulation of chronic conditions","volume":"5","author":"Bobo","year":"2022","journal-title":"JAMA Netw. Open"},{"key":"B44","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1126\/science.1123511","article-title":"Onset and progression in inherited ALS determined by motor neurons and microglia","volume":"312","author":"Boill\u00e9e","year":"2006","journal-title":"Science"},{"key":"B45","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.neurobiolaging.2019.11.004","article-title":"Gut microbiota manipulation through probiotics oral administration restores glucose homeostasis in a mouse model of Alzheimer's disease","volume":"87","author":"Bonfili","year":"2020","journal-title":"Neurobiol. Aging"},{"key":"B46","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1017\/S0033291722000897","article-title":"Role of the gut microbiome in three major psychiatric disorders","volume":"52","author":"Borkent","year":"2022","journal-title":"Psychol. Med."},{"key":"B47","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1097\/MOG.0000000000000027","article-title":"Therapeutic faecal microbiota transplantation: current status and future developments","volume":"30","author":"Borody","year":"2014","journal-title":"Curr. Opin. Gastroenterol."},{"key":"B48","first-page":"289","article-title":"The effects of probiotic supplementation on gene expression related to inflammation, insulin and lipid in patients with Parkinson's disease: a randomized, double-blind, placebocontrolled trial","volume":"21","author":"Borzabadi","year":"2018","journal-title":"Arch. Iran. Med."},{"key":"B49","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/s40168-024-01858-1","article-title":"Systemic antibody responses against gut microbiota flagellins implicate shared and divergent immune reactivity in Crohn's disease and chronic fatigue syndrome","volume":"12","author":"Bourgonje","year":"2024","journal-title":"Microbiome"},{"key":"B50","doi-asserted-by":"publisher","first-page":"16050","DOI":"10.1073\/pnas.1102999108","article-title":"Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve","volume":"108","author":"Bravo","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B51","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1093\/brain\/awx370","article-title":"Hot-spot KIF5A mutations cause familial ALS","volume":"141","author":"Brenner","year":"2018","journal-title":"Brain"},{"key":"B52","doi-asserted-by":"publisher","first-page":"1015","DOI":"10.3389\/fneur.2020.01015","article-title":"Evaluation of an immunomodulatory probiotic intervention for veterans with co-occurring mild traumatic brain injury and posttraumatic stress disorder: a pilot study","volume":"11","author":"Brenner","year":"2020","journal-title":"Front. Neurol."},{"key":"B53","unstructured":"\u201cAmyotrophic Lateral Sclerosis,\u201d\n          \n          \n            \n              Brotman\n              R. G.\n            \n            \n              Moreno-Escobar\n              M. C.\n            \n            \n              Joseph\n              J.\n            \n            \n              Munakomi\n              S.\n            \n            \n              Pawar\n              G.\n            \n          \n          Treasure Island, FL\n          StatPearls Publishing\n          StatPearls\n          \n          2025"},{"key":"B54","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1080\/1028415X.2023.2277970","article-title":"Associations between short-chain fatty acid levels and mood disorder symptoms: a systematic review","volume":"27","author":"Bruun","year":"2024","journal-title":"Nutr. Neurosci."},{"key":"B55","doi-asserted-by":"publisher","first-page":"167034","DOI":"10.1016\/j.scitotenv.2023.167034","article-title":"Maternal exposure of mice to glyphosate induces depression- and anxiety-like behavior in the offspring via alterations of the gut-brain axis","volume":"905","author":"Buchenauer","year":"2023","journal-title":"Sci. Total Environ."},{"key":"B56","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/j.biopsych.2016.12.031","article-title":"Targeting the microbiota-gut-brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice","volume":"82","author":"Burokas","year":"2017","journal-title":"Biol. Psychiatry"},{"key":"B57","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/j.ajcnut.2023.01.018","article-title":"Associations between fecal short-chain fatty acids, plasma inflammatory cytokines, and dietary markers with depression and anxiety: post hoc analysis of the ENGAGE-2 pilot trial","volume":"117","author":"Burton","year":"2023","journal-title":"Am. J. Clin. Nutr."},{"key":"B58","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1038\/s41398-023-02325-5","article-title":"The gut microbiome in social anxiety disorder: evidence of altered composition and function","volume":"13","author":"Butler","year":"2023","journal-title":"Transl. Psychiatry"},{"key":"B59","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.bbi.2021.10.020","article-title":"The immune-kynurenine pathway in social anxiety disorder","volume":"99","author":"Butler","year":"2022","journal-title":"Brain Behav. Immun."},{"key":"B60","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.jad.2025.04.018","article-title":"Effects of fecal microbiota transplantation from patients with generalized anxiety on anxiety-like behaviors: the role of the gut-microbiota-endocannabinoid-brain axis","volume":"381","author":"Cai","year":"2025","journal-title":"J. Affect. Disord."},{"key":"B61","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1136\/jech-2021-218074","article-title":"Effects of depression on employment and social outcomes: a Mendelian randomisation study","volume":"76","author":"Campbell","year":"2022","journal-title":"J. Epidemiol. Community Health"},{"key":"B62","doi-asserted-by":"publisher","first-page":"269","DOI":"10.3389\/fnagi.2019.00269","article-title":"Is AD a stress-related disorder? Focus on the HPA axis and its promising therapeutic targets","volume":"11","author":"Canet","year":"2019","journal-title":"Front. Aging Neurosci."},{"key":"B63","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1097\/JIM.0000000000000192","article-title":"Gut microbiota in multiple sclerosis: possible influence of immunomodulators","volume":"63","author":"Cantarel","year":"2015","journal-title":"J. Investig. Med."},{"key":"B64","doi-asserted-by":"publisher","first-page":"3757","DOI":"10.1007\/s00394-021-02543-x","article-title":"Bifidobacterium lactis Probio-M8 regulates gut microbiota to alleviate Alzheimer's disease in the APP\/PS1 mouse model","volume":"60","author":"Cao","year":"2021","journal-title":"Eur. J. Nutr."},{"key":"B65","doi-asserted-by":"publisher","first-page":"182","DOI":"10.3390\/nu16020182","article-title":"Nutrition and chronobiology as key components of multidisciplinary therapeutic interventions for fibromyalgia and associated chronic fatigue syndrome: a narrative and critical review","volume":"16","author":"Carrasco-Querol","year":"2024","journal-title":"Nutrients"},{"key":"B66","first-page":"117","article-title":"Use of probiotics for the treatment of constipation in Parkinson's disease patients","volume":"57","author":"Cassani","year":"2011","journal-title":"Minerva Gastroenterol. Dietol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1007\/s40495-019-00203-7","article-title":"Using zebrafish to investigate interactions between xenobiotics and microbiota","volume":"5","author":"Catron","year":"2019","journal-title":"Curr. Pharmacol. Rep."},{"key":"B68","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.neurobiolaging.2016.08.019","article-title":"Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly","volume":"49","author":"Cattaneo","year":"2017","journal-title":"Neurobiol. Aging"},{"key":"B69","doi-asserted-by":"publisher","first-page":"10713","DOI":"10.1073\/pnas.1711235114","article-title":"Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models","volume":"114","author":"Cekanaviciute","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B70","doi-asserted-by":"publisher","first-page":"1332","DOI":"10.1007\/s00415-012-6801-2","article-title":"Gastrointestinal manifestations in Parkinson's disease: prevalence and occurrence before motor symptoms","volume":"260","author":"Cersosimo","year":"2013","journal-title":"J. Neurol."},{"key":"B71","doi-asserted-by":"publisher","first-page":"4227","DOI":"10.3390\/ijms26094227","article-title":"Delayed impact of ionizing radiation depends on sex: integrative metagenomics and metabolomics analysis of rodent colon content","volume":"26","author":"Chakraborty","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"B72","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s13024-023-00595-7","article-title":"The gut microbiome in Alzheimer's disease: what we know and what remains to be explored","volume":"18","author":"Chandra","year":"2023","journal-title":"Mol. Neurodegener."},{"key":"B73","doi-asserted-by":"publisher","first-page":"207","DOI":"10.31887\/DCNS.2003.5.3\/dcharney","article-title":"The psychobiology of resilience and vulnerability to anxiety disorders: implications for prevention and treatment","volume":"5","author":"Charney","year":"2003","journal-title":"Dial. Clin. Neurosci."},{"key":"B74","doi-asserted-by":"publisher","first-page":"403","DOI":"10.3389\/fnagi.2017.00403","article-title":"Prebiotic effect of fructooligosaccharides from Morinda officinalis on Alzheimer's disease in rodent models by targeting the microbiota-gut-brain axis","volume":"9","author":"Chen","year":"2017","journal-title":"Front. Aging Neurosci."},{"key":"B75","doi-asserted-by":"publisher","first-page":"28484","DOI":"10.1038\/srep28484","article-title":"Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls","volume":"6","author":"Chen","year":"2016","journal-title":"Sci. Rep."},{"key":"B76","doi-asserted-by":"publisher","first-page":"115000","DOI":"10.1016\/j.ecoenv.2023.115000","article-title":"Polystyrene micro- and nanoparticles exposure induced anxiety-like behaviors, gut microbiota dysbiosis and metabolism disorder in adult mice","volume":"259","author":"Chen","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"B77","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.jad.2019.08.014","article-title":"Association between fecal microbiota and generalized anxiety disorder: severity and early treatment response","volume":"259","author":"Chen","year":"2019","journal-title":"J. Affect. Disord."},{"key":"B78","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1016\/j.jad.2020.12.143","article-title":"Gut microbiota dysbiosis in depressed women: the association of symptom severity and microbiota function","volume":"282","author":"Chen","year":"2021","journal-title":"J. Affect. Disord."},{"key":"B79","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1146\/annurev-nutr-082018-124344","article-title":"Bile acids as metabolic regulators and nutrient sensors","volume":"39","author":"Chiang","year":"2019","journal-title":"Annu. Rev. Nutr."},{"key":"B80","doi-asserted-by":"publisher","first-page":"110183","DOI":"10.1016\/j.neuropharm.2024.110183","article-title":"Glyphosate impairs both structure and function of GABAergic synapses in hippocampal neurons","volume":"262","author":"Chiantia","year":"2025","journal-title":"Neuropharmacology"},{"key":"B81","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1159\/000351153","article-title":"Global epidemiology of amyotrophic lateral sclerosis: a systematic review of the published literature","volume":"41","author":"Chi\u00f2","year":"2013","journal-title":"Neuroepidemiology"},{"key":"B82","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.jpsychires.2019.01.016","article-title":"Exploration of microbiota targets for major depressive disorder and mood related traits","volume":"111","author":"Chung","year":"2019","journal-title":"J. Psychiatr. Res."},{"key":"B83","doi-asserted-by":"publisher","first-page":"1134080","DOI":"10.3389\/fnins.2023.1134080","article-title":"Serum short chain fatty acids mediate hippocampal BDNF and correlate with decreasing neuroinflammation following high pectin fiber diet in mice","volume":"17","author":"Church","year":"2023","journal-title":"Front. Neurosci."},{"key":"B84","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1124\/pr.112.005850","article-title":"Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales","volume":"64","author":"Clark","year":"2012","journal-title":"Pharmacol. Rev."},{"key":"B85","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1038\/mp.2012.77","article-title":"The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner","volume":"18","author":"Clarke","year":"2013","journal-title":"Mol. Psychiatry"},{"key":"B86","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1080\/19490976.2017.1353843","article-title":"A bidirectional association between the gut microbiota and CNS disease in a biphasic murine model of multiple sclerosis","volume":"8","author":"Colpitts","year":"2017","journal-title":"Gut Microbes"},{"key":"B87","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1186\/s12974-023-02887-7","article-title":"Stabilizing histamine release in gut mast cells mitigates peripheral and central inflammation after stroke","volume":"20","author":"Conesa","year":"2023","journal-title":"J. Neuroinflamm."},{"key":"B88","doi-asserted-by":"publisher","first-page":"e113","DOI":"10.1016\/j.biopsych.2011.03.028","article-title":"Inverted-U\u2013shaped dopamine actions on human working memory and cognitive control","volume":"69","author":"Cools","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"B89","doi-asserted-by":"publisher","first-page":"e1700492","DOI":"10.1126\/sciadv.1700492","article-title":"High frequency of intestinal TH 17 cells correlates with microbiota alterations and disease activity in multiple sclerosis","volume":"3","author":"Cosorich","year":"2017","journal-title":"Sci. Adv."},{"key":"B90","doi-asserted-by":"publisher","first-page":"e0187964","DOI":"10.1371\/journal.pone.0187964","article-title":"An in vivo assessment of the cholesterol-lowering efficacy of Lactobacillus plantarum ECGC 13110402 in normal to mildly hypercholesterolaemic adults","volume":"12","author":"Costabile","year":"2017","journal-title":"PLoS ONE"},{"key":"B91","doi-asserted-by":"publisher","first-page":"4605","DOI":"10.3390\/ijms23094605","article-title":"Toxic effects of glyphosate on the nervous system: a systematic review","volume":"23","author":"Costas-Ferreira","year":"2022","journal-title":"IJMS"},{"key":"B92","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1001\/archsurg.1951.01250040701017","article-title":"Vagotomy in the treatment of biliary dyskinesia","volume":"63","author":"Crile","year":"1951","journal-title":"Arch. Surg."},{"key":"B93","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1111\/j.1365-2982.2010.01664.x","article-title":"The microbiome-gut-brain axis: from bowel to behavior","volume":"23","author":"Cryan","year":"2011","journal-title":"Neurogastroenterol. Motil."},{"key":"B94","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1038\/s41392-024-01738-y","article-title":"Major depressive disorder: hypothesis, mechanism, prevention and treatment","volume":"9","author":"Cui","year":"2024","journal-title":"Sig. Transduct. Target. Ther."},{"key":"B95","doi-asserted-by":"publisher","first-page":"2333","DOI":"10.1016\/j.bbadis.2017.06.021","article-title":"Total abdominal irradiation exposure impairs cognitive function involving miR-34a-5p\/BDNF axis","volume":"1863","author":"Cui","year":"","journal-title":"Biochim. Biophys. Acta"},{"key":"B96","doi-asserted-by":"publisher","first-page":"448","DOI":"10.15252\/emmm.201606932","article-title":"Faecal microbiota transplantation protects against radiation-induced toxicity","volume":"9","author":"Cui","year":"","journal-title":"EMBO Mol. Med."},{"key":"B97","doi-asserted-by":"publisher","first-page":"11663","DOI":"10.3390\/ijms222111663","article-title":"Small intestinal bacterial overgrowth as potential therapeutic target in Parkinson's disease","volume":"22","author":"D\u0103n\u0103u","year":"2021","journal-title":"IJMS"},{"key":"B98","doi-asserted-by":"publisher","first-page":"155636","DOI":"10.1016\/j.phymed.2024.155636","article-title":"Sijunzi decoction, a classical Chinese herbal formula, improves fatigue symptoms with changes in gut microbiota in chronic fatigue syndrome: a randomized, double-blind, placebo-controlled, multi-center clinical trial","volume":"129","author":"Dai","year":"2024","journal-title":"Phytomedicine"},{"key":"B99","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1001\/jamapsychiatry.2020.3285","article-title":"Effects of psilocybin-assisted therapy on major depressive disorder: a randomized clinical trial","volume":"78","author":"Davis","year":"2021","journal-title":"JAMA Psychiatry"},{"key":"B100","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1038\/s41583-022-00558-9","article-title":"Impaired insulin signalling and allostatic load in Alzheimer disease","volume":"23","author":"De Felice","year":"2022","journal-title":"Nat. Rev. Neurosci."},{"key":"B101","doi-asserted-by":"publisher","first-page":"1812","DOI":"10.1136\/gutjnl-2015-309957","article-title":"High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome","volume":"65","author":"De Filippis","year":"2016","journal-title":"Gut"},{"key":"B102","doi-asserted-by":"publisher","first-page":"4482","DOI":"10.1038\/s41467-024-48739-7","article-title":"Exposure to environmental pollutants selects for xenobiotic-degrading functions in the human gut microbiome","volume":"15","author":"De Filippis","year":"2024","journal-title":"Nat. Commun."},{"key":"B103","doi-asserted-by":"publisher","first-page":"419","DOI":"10.4161\/gmic.29417","article-title":"The microbiota-gut-brain axis in functional gastrointestinal disorders","volume":"5","author":"De Palma","year":"2014","journal-title":"Gut Microbes"},{"key":"B104","doi-asserted-by":"publisher","first-page":"223","DOI":"10.3389\/fimmu.2015.00223","article-title":"Stress induces endotoxemia and low-grade inflammation by increasing barrier permeability","volume":"6","author":"De Punder","year":"2015","journal-title":"Front. Immunol."},{"key":"B105","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1192\/bjp.bp.115.173450","article-title":"Influence of baseline severity on antidepressant efficacy for anxiety disorders: Meta-analysis and meta-regression","volume":"208","author":"De Vries","year":"2016","journal-title":"Br. J. Psychiatry"},{"key":"B106","doi-asserted-by":"publisher","first-page":"5583","DOI":"10.3390\/ijms23105583","article-title":"Lifelong exposure to a low-dose of the glyphosate-based herbicide RoundUp\u00ae causes intestinal damage, gut dysbiosis, and behavioral changes in mice","volume":"23","author":"Del Castilo","year":"2022","journal-title":"IJMS"},{"key":"B107","doi-asserted-by":"publisher","first-page":"480","DOI":"10.14336\/AD.2023.0727","article-title":"Gut metabolites acting on the gut-brain axis: regulating the functional state of microglia","volume":"15","author":"Deng","year":"2024","journal-title":"Aging Dis."},{"key":"B108","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.bbi.2015.04.004","article-title":"Gut microbiota depletion from early adolescence in mice: implications for brain and behaviour","volume":"48","author":"Desbonnet","year":"2015","journal-title":"Brain Behav. Immun."},{"key":"B109","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1111\/bdi.12652","article-title":"Adjunctive probiotic microorganisms to prevent rehospitalization in patients with acute mania: a randomized controlled trial","volume":"20","author":"Dickerson","year":"2018","journal-title":"Bipolar Disord."},{"key":"B110","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.radonc.2020.01.011","article-title":"Fecal microbiota transplantation: a promising treatment for radiation enteritis?","volume":"143","author":"Ding","year":"2020","journal-title":"Radiother. Oncol."},{"key":"B111","doi-asserted-by":"publisher","first-page":"8411","DOI":"10.1007\/s00253-021-11622-2","article-title":"A next-generation probiotic: Akkermansia muciniphila ameliorates chronic stress\u2013induced depressive-like behavior in mice by regulating gut microbiota and metabolites","volume":"105","author":"Ding","year":"2021","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"B112","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1111\/j.1523-5378.2010.00768.x","article-title":"Differential effect of Helicobacter pylori eradication on time-trends in brady\/hypokinesia and rigidity in idiopathic parkinsonism: report on completion of a randomized, double-blind, placebo-controlled efficacy study","volume":"15","author":"Dobbs","year":"2010","journal-title":"Helicobacter"},{"key":"B113","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1111\/ene.13819","article-title":"Multiple sclerosis \u2013 a review","volume":"26","author":"Dobson","year":"2019","journal-title":"Euro. J. Neurol."},{"key":"B114","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.1084\/jem.20182386","article-title":"Sex-specific effects of microbiome perturbations on cerebral A\u03b2 amyloidosis and microglia phenotypes","volume":"216","author":"Dodiya","year":"2019","journal-title":"J. Exp. Med."},{"key":"B115","doi-asserted-by":"publisher","first-page":"815422","DOI":"10.3389\/fpsyt.2022.815422","article-title":"Fecal microbiota transplantation (FMT) as an adjunctive therapy for depression\u2014case report","volume":"13","author":"Doll","year":"2022","journal-title":"Front. Psychiatry"},{"key":"B116","doi-asserted-by":"publisher","first-page":"813075","DOI":"10.3389\/fnins.2022.813075","article-title":"Gut microbiome: a potential indicator for predicting treatment outcomes in major depressive disorder","volume":"16","author":"Dong","year":"2022","journal-title":"Front. Neurosci."},{"key":"B117","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1177\/10738584211024907","article-title":"T cells: a growing universe of roles in neurodegenerative diseases","volume":"28","author":"Dressman","year":"2022","journal-title":"Neuroscientist"},{"key":"B118","doi-asserted-by":"publisher","first-page":"228","DOI":"10.3758\/s13415-024-01162-3","article-title":"Understanding the heterogeneity of anxiety using a translational neuroscience approach","volume":"24","author":"Drzewiecki","year":"2024","journal-title":"Cogn. Affect. Behav. Neurosci."},{"key":"B119","doi-asserted-by":"publisher","first-page":"7379","DOI":"10.3390\/ijms25137379","article-title":"The role of short chain fatty acids in inflammation and body health","volume":"25","author":"Du","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"B120","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2015\/797862","article-title":"Elevated blood ammonia level is a potential biological risk factor of behavioral disorders in prisoners","volume":"2015","author":"Duan","year":"2015","journal-title":"Behav. Neurol."},{"key":"B121","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1002\/mus.27784","article-title":"The \u201cmetabolic axis\u201d of ALS: the role of body weight in disease pathogenesis","volume":"67","author":"Dupuis","year":"2023","journal-title":"Muscle Nerve"},{"key":"B122","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1038\/s41588-021-00950-8","article-title":"Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders","volume":"53","author":"Eijsbouts","year":"2021","journal-title":"Nat. Genet."},{"key":"B123","doi-asserted-by":"publisher","first-page":"6057","DOI":"10.1097\/MS9.0000000000001441","article-title":"Stroke and cognitive impairment: understanding the connection and managing symptoms","volume":"85","author":"Elendu","year":"2023","journal-title":"Ann. Med. Surg."},{"key":"B124","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1002\/mds.28004","article-title":"Implications of the gut microbiome in Parkinson's disease","volume":"35","author":"Elfil","year":"2020","journal-title":"Mov. Disord."},{"key":"B125","doi-asserted-by":"publisher","first-page":"13690","DOI":"10.4081\/ejtm.2025.13690","article-title":"The microbiota-gut-brain axis in myalgic encephalomyelitis\/chronic fatigue syndrome: a narrative review of an emerging field","volume":"35","author":"El-Sehrawy","year":"2025","journal-title":"Eur. J. Transl. Myol."},{"key":"B126","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3389\/fnagi.2017.00195","article-title":"16S rRNA next generation sequencing analysis shows bacteria in Alzheimer's post-mortem brain","volume":"9","author":"Emery","year":"2017","journal-title":"Front. Aging Neurosci."},{"key":"B127","doi-asserted-by":"publisher","first-page":"978","DOI":"10.3389\/fneur.2020.00978","article-title":"Single-arm, non-randomized, time series, single-subject study of fecal microbiota transplantation in multiple sclerosis","volume":"11","author":"Engen","year":"2020","journal-title":"Front. Neurol."},{"key":"B128","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1001\/jamapsychiatry.2013.4374","article-title":"Assessment of plasma C-reactive protein as a biomarker of posttraumatic stress disorder risk","volume":"71","author":"Eraly","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"B129","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1038\/nn.4030","article-title":"Host microbiota constantly control maturation and function of microglia in the CNS","volume":"18","author":"Erny","year":"2015","journal-title":"Nat. Neurosci."},{"key":"B130","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1038\/s41593-020-00783-4","article-title":"Reactive astrocyte nomenclature, definitions, and future directions","volume":"24","author":"Escartin","year":"2021","journal-title":"Nat. Neurosci."},{"key":"B131","first-page":"10","article-title":"The efficacy of probiotics for treatment of bipolar disorder-type 1: a randomized, double-blind, placebo controlled trial","volume":"15","author":"Eslami Shahrbabaki","year":"2020","journal-title":"Iran. J. Psychiatry"},{"key":"B132","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.jpsychires.2016.12.007","article-title":"The gut microbiome composition associates with bipolar disorder and illness severity","volume":"87","author":"Evans","year":"2017","journal-title":"J. Psychiatr. Res."},{"key":"B133","doi-asserted-by":"publisher","first-page":"13","DOI":"10.5498\/wjp.v2.i1.13","article-title":"Childhood stressful events, HPA axis and anxiety disorders","volume":"2","author":"Faravelli","year":"2012","journal-title":"WJP"},{"key":"B134","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1002\/mds.25522","article-title":"The role of small intestinal bacterial overgrowth in Parkinson's disease","volume":"28","author":"Fasano","year":"2013","journal-title":"Mov. Disord."},{"key":"B135","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.parkreldis.2016.03.012","article-title":"Microbiota-gut-brain signalling in Parkinson's disease: implications for non-motor symptoms","volume":"27","author":"Felice","year":"2016","journal-title":"Parkinson. Relat. Disord."},{"key":"B136","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1002\/phar.1890","article-title":"Interaction between atypical antipsychotics and the gut microbiome in a bipolar disease cohort","volume":"37","author":"Flowers","year":"2017","journal-title":"Pharmacotherapy"},{"key":"B137","doi-asserted-by":"publisher","first-page":"130010","DOI":"10.1016\/j.jhazmat.2022.130010","article-title":"Microplastics: What happens in the human digestive tract? First evidences in adults using in vitro gut models","volume":"442","author":"Fournier","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"B138","doi-asserted-by":"publisher","first-page":"170228","DOI":"10.1098\/rsob.170228","article-title":"The role of astrocytes in amyloid production and Alzheimer's disease","volume":"7","author":"Frost","year":"2017","journal-title":"Open Biol."},{"key":"B139","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1038\/nn.4476","article-title":"Interactions between the microbiota, immune and nervous systems in health and disease","volume":"20","author":"Fung","year":"2017","journal-title":"Nat. Neurosci."},{"key":"B140","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1111\/j.1365-2990.2010.01135.x","article-title":"Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles: granulovacuolar degeneration bodies and autophagy","volume":"37","author":"Funk","year":"2011","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"B141","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1002\/mds.23566","article-title":"Prevalence of small intestinal bacterial overgrowth in Parkinson's disease","volume":"26","author":"Gabrielli","year":"2011","journal-title":"Mov. Disord."},{"key":"B142","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1089\/jmf.2014.7000","article-title":"The Gut Microbiome and the Brain","volume":"17","author":"Galland","year":"2014","journal-title":"J. Med. Food"},{"key":"B143","unstructured":"\u201cLevodopa (L-Dopa),\u201d\n          \n          \n            \n              Gandhi\n              K. R.\n            \n            \n              Saadabadi\n              A.\n            \n          \n          Treasure Island, FL\n          StatPearls Publishing\n          StatPearls\n          \n          2025"},{"key":"B144","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1136\/gut.2009.202515","article-title":"Bacterial infection causes stress-induced memory dysfunction in mice","volume":"60","author":"Gareau","year":"2011","journal-title":"Gut"},{"key":"B145","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.2147\/CIA.S106284","article-title":"Nonmotor gastrointestinal disorders in older patients with Parkinson's disease: is there hope?","volume":"11","author":"Georgescu","year":"2016","journal-title":"CIA"},{"key":"B146","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1038\/s41593-020-00748-7","article-title":"Transcriptomic organization of the human brain in post-traumatic stress disorder","volume":"24","author":"Girgenti","year":"2021","journal-title":"Nat. Neurosci."},{"key":"B147","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1016\/S0006-291X(84)80190-4","article-title":"Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein","volume":"120","author":"Glenner","year":"1984","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B148","doi-asserted-by":"publisher","first-page":"127","DOI":"10.3389\/fnbeh.2018.00127","article-title":"A comprehensive overview on stress neurobiology: basic concepts and clinical implications","volume":"12","author":"Godoy","year":"2018","journal-title":"Front. Behav. Neurosci."},{"key":"B149","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1007\/s10072-016-2782-8","article-title":"Serum glutathione peroxidase, xanthine oxidase, and superoxide dismutase activities and malondialdehyde levels in patients with Parkinson's disease","volume":"38","author":"G\u00f6k\u00e7e \u00c7okal","year":"2017","journal-title":"Neurol. Sci."},{"key":"B150","doi-asserted-by":"publisher","first-page":"11245","DOI":"10.3390\/ijms231911245","article-title":"The microbiota-gut-brain axis in psychiatric disorders","volume":"23","author":"G\u00f3ralczyk-Bi\u0144kowska","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"B151","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/S1474-4422(21)00414-2","article-title":"Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis","volume":"21","author":"Goutman","year":"2022","journal-title":"Lancet Neurol."},{"key":"B152","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1016\/S0140-6736(15)00241-X","article-title":"Bipolar disorder","volume":"387","author":"Grande","year":"2016","journal-title":"Lancet"},{"key":"B153","doi-asserted-by":"publisher","first-page":"5982","DOI":"10.3390\/ijms21175982","article-title":"Bile acid signaling in neurodegenerative and neurological disorders","volume":"21","author":"Grant","year":"2020","journal-title":"IJMS"},{"key":"B154","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1177\/07067437221150508","article-title":"Feasibility, acceptability, and safety of faecal microbiota transplantation in the treatment of major depressive disorder: a pilot randomized controlled trial","volume":"68","author":"Green","year":"2023","journal-title":"Can. J. Psychiatry"},{"key":"B155","doi-asserted-by":"publisher","first-page":"e0245323","DOI":"10.1371\/journal.pone.0245323","article-title":"Psychological, physical, and sleep comorbidities and functional impairment in irritable bowel syndrome: results from a national survey of U.S. adults","volume":"16","author":"Grover","year":"2021","journal-title":"PLoS ONE"},{"key":"B156","doi-asserted-by":"publisher","first-page":"1596","DOI":"10.1111\/aogs.14864","article-title":"Antibiotic or gastric acid inhibitor use during pregnancy and postpartum depression: Population-based cohort study","volume":"103","author":"Gudnadottir","year":"2024","journal-title":"Acta Obstet. Gynecol. Scand."},{"key":"B157","doi-asserted-by":"publisher","first-page":"193","DOI":"10.3148\/cjdpr-2022-014","article-title":"Perceptions and experiences of nutrition interventions in individuals with amyotrophic lateral sclerosis (ALS) and their caregivers","volume":"83","author":"Guillemin","year":"2022","journal-title":"Can. J. Diet. Pract. Res."},{"key":"B158","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/j.chom.2023.01.004","article-title":"Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME\/CFS","volume":"31","author":"Guo","year":"2023","journal-title":"Cell Host Microbe"},{"key":"B159","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/S1470-2045(15)70134-8","article-title":"Carcinogenicity of tetrachlorvinphos, parathion, malathion, diazinon, and glyphosate","volume":"16","author":"Guyton","year":"2015","journal-title":"Lancet Oncol."},{"key":"B160","doi-asserted-by":"publisher","first-page":"97","DOI":"10.3233\/BPL-220141","article-title":"Microbiota-gut-brain axis regulation of adult hippocampal neurogenesis","volume":"8","author":"Guzzetta","year":"2022","journal-title":"Brain Plast"},{"key":"B161","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1016\/j.bbr.2011.12.027","article-title":"Lipopolysaccharide affects exploratory behaviors toward novel objects by impairing cognition and\/or motivation in mice: possible role of activation of the central amygdala","volume":"228","author":"Haba","year":"2012","journal-title":"Behav. Brain Res."},{"key":"B162","doi-asserted-by":"publisher","DOI":"10.1242\/dev.202449","article-title":"Reelin differentially shapes dendrite morphology of medial entorhinal cortical ocean and island cells","author":"Hamad","year":"","journal-title":"Development"},{"key":"B163","doi-asserted-by":"publisher","first-page":"1254589","DOI":"10.3389\/fcell.2023.1254589","article-title":"Extracellular molecular signals shaping dendrite architecture during brain development","volume":"11","author":"Hamad","year":"2023","journal-title":"Front. Cell. Dev. Biol."},{"key":"B164","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1111\/jnc.14990","article-title":"Reelin signaling modulates GABAB receptor function in the neocortex","volume":"156","author":"Hamad","year":"","journal-title":"J. Neurochem."},{"key":"B165","doi-asserted-by":"publisher","first-page":"dev199718","DOI":"10.1242\/dev.199718","article-title":"Reelin restricts dendritic growth of interneurons in the neocortex","volume":"148","author":"Hamad","year":"","journal-title":"Development"},{"key":"B166","doi-asserted-by":"publisher","first-page":"593","DOI":"10.3390\/biom14050593","article-title":"Reelin regulates developmental desynchronization transition of neocortical network activity","volume":"14","author":"Hamad","year":"","journal-title":"Biomolecules"},{"key":"B167","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1038\/s41598-023-50781-2","article-title":"Maternal exposure to polyethylene micro- and nanoplastics impairs umbilical blood flow but not fetal growth in pregnant mice","volume":"14","author":"Hanrahan","year":"2024","journal-title":"Sci. Rep."},{"key":"B168","doi-asserted-by":"publisher","first-page":"619103","DOI":"10.3389\/fphar.2021.619103","article-title":"Xiaoyaosan improves antibiotic-induced depressive-like and anxiety-like behavior in mice through modulating the gut microbiota and regulating the NLRP3 inflammasome in the colon","volume":"12","author":"Hao","year":"2021","journal-title":"Front. Pharmacol."},{"key":"B169","doi-asserted-by":"publisher","first-page":"e00632","DOI":"10.1128\/mBio.00632-19","article-title":"Alzheimer's disease microbiome is associated with dysregulation of the anti-inflammatory P-glycoprotein pathway","volume":"10","author":"Haran","year":"2019","journal-title":"MBio"},{"key":"B170","doi-asserted-by":"publisher","first-page":"113331","DOI":"10.1016\/j.expneurol.2020.113331","article-title":"PTSD-related neuroimaging abnormalities in brain function, structure, and biochemistry","volume":"330","author":"Harnett","year":"2020","journal-title":"Exp. Neurol."},{"key":"B171","doi-asserted-by":"publisher","first-page":"e112330","DOI":"10.1371\/journal.pone.0112330","article-title":"Eradication of Helicobacter pylori infection improves levodopa action, clinical symptoms and quality of life in patients with Parkinson's disease","volume":"9","author":"Hashim","year":"2014","journal-title":"PLoS ONE"},{"key":"B172","doi-asserted-by":"publisher","first-page":"429","DOI":"10.3390\/applmicrobiol3020030","article-title":"The role of an altered gut microbiome in Parkinson's disease: a narrative review","volume":"3","author":"Hashish","year":"2023","journal-title":"Appl. Microbiol."},{"key":"B173","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1093\/brain\/awh129","article-title":"Disrupted daily activity\/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia","volume":"127","author":"Hatfield","year":"2004","journal-title":"Brain"},{"key":"B174","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1002\/cpt.1870","article-title":"The microbiome and the gut-liver-brain axis for central nervous system clinical pharmacology: challenges in specifying and integrating in vitro and in silico models","volume":"108","author":"Hawkins","year":"2020","journal-title":"Clin. Pharma Therap."},{"key":"B175","doi-asserted-by":"publisher","first-page":"0300060520925930","DOI":"10.1177\/0300060520925930","article-title":"Rapid improvement in Alzheimer's disease symptoms following fecal microbiota transplantation: a case report","volume":"48","author":"Hazan","year":"2020","journal-title":"J. Int. Med. Res."},{"key":"B176","doi-asserted-by":"publisher","first-page":"1190894","DOI":"10.3389\/fmicb.2023.1190894","article-title":"Causal effects between gut microbiome and myalgic encephalomyelitis\/chronic fatigue syndrome: a two-sample mendelian randomization study","volume":"14","author":"He","year":"2023","journal-title":"Front. Microbiol."},{"key":"B177","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1038\/s41398-024-02765-7","article-title":"Potential causal association between gut microbiome and posttraumatic stress disorder","volume":"14","author":"He","year":"2024","journal-title":"Transl. Psychiatry"},{"key":"B178","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.1038\/s41430-019-0556-0","article-title":"Association between the faecal short-chain fatty acid propionate and infant sleep","volume":"74","author":"Heath","year":"2020","journal-title":"Eur. J. Clin. Nutr."},{"key":"B179","author":"Hegde","year":"2022","journal-title":"Assessment of Communication Disorders in Adults: Resources and Protocols, 3rd Edn"},{"key":"B180","doi-asserted-by":"publisher","first-page":"3047","DOI":"10.1073\/pnas.1010529108","article-title":"Normal gut microbiota modulates brain development and behavior","volume":"108","author":"Heijtz","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B181","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1002\/mds.27105","article-title":"The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder","volume":"33","author":"Heintz-Buschart","year":"2018","journal-title":"Mov. Disord."},{"key":"B182","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1097\/PSY.0000000000000512","article-title":"The microbiome in posttraumatic stress disorder and trauma-exposed controls: an exploratory study","volume":"79","author":"Hemmings","year":"2017","journal-title":"Psychosom. Med."},{"key":"B183","doi-asserted-by":"publisher","first-page":"3671","DOI":"10.3390\/cancers16213671","article-title":"The role of the microbiome and of radiotherapy-derived metabolites in breast cancer","volume":"16","author":"Herrera-Quintana","year":"2024","journal-title":"Cancers"},{"key":"B184","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1111\/j.1600-0447.1993.tb03372.x","article-title":"The distinction of bipolar II disorder from bipolar I and recurrent unipolar depression: results of a controlled family study","volume":"87","author":"Heun","year":"1993","journal-title":"Acta Psychiatr. Scand."},{"key":"B185","doi-asserted-by":"publisher","first-page":"1151850","DOI":"10.3389\/fnagi.2023.1151850","article-title":"Therapies for Parkinson's disease and the gut microbiome: evidence for bidirectional connection","volume":"15","author":"Hey","year":"2023","journal-title":"Front. Aging Neurosci."},{"key":"B186","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1161\/CIRCRESAHA.122.319983","article-title":"Aging microbiota-gut-brain axis in stroke risk and outcome","volume":"130","author":"Honarpisheh","year":"2022","journal-title":"Circ. Res."},{"key":"B187","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.3390\/ijms21051711","article-title":"Dysregulated gut homeostasis observed prior to the accumulation of the brain amyloid-\u03b2 in Tg2576 mice","volume":"21","author":"Honarpisheh","year":"2020","journal-title":"IJMS"},{"key":"B188","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.brainres.2017.04.019","article-title":"Gut microbiota in Parkinson disease in a northern German cohort","volume":"1667","author":"Hopfner","year":"2017","journal-title":"Brain Res."},{"key":"B189","doi-asserted-by":"publisher","first-page":"3077","DOI":"10.1093\/brain\/awaa238","article-title":"Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study","volume":"143","author":"Horsager","year":"2020","journal-title":"Brain"},{"key":"B190","doi-asserted-by":"publisher","first-page":"1504","DOI":"10.2967\/jnumed.121.262300","article-title":"Radionuclide imaging of the gut\u2013brain axis in Parkinson disease","volume":"62","author":"Horsager","year":"2021","journal-title":"J. Nucl. Med."},{"key":"B191","doi-asserted-by":"publisher","first-page":"105626","DOI":"10.1016\/j.nbd.2022.105626","article-title":"Clinical and imaging evidence of brain-first and body-first Parkinson's disease","volume":"164","author":"Horsager","year":"2022","journal-title":"Neurobiol. Dis."},{"key":"B192","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1038\/s43247-025-02169-5","article-title":"Complexities of the global plastics supply chain revealed in a trade-linked material flow analysis","volume":"6","author":"Houssini","year":"2025","journal-title":"Commun. Earth Environ."},{"key":"B193","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2023.116860","article-title":"Association between glyphosate exposure and cognitive function, depression, and neurological diseases in a representative sample of US adults: NHANES 2013\u20132014 analysis","author":"Hsiao","year":"2023","journal-title":"Environ. Res."},{"key":"B194","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1186\/s12967-025-06527-x","article-title":"The potential therapeutic approaches targeting gut health in myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS): a narrative review","volume":"23","author":"Hsu","year":"2025","journal-title":"J. Transl. Med."},{"key":"B195","doi-asserted-by":"publisher","first-page":"114142","DOI":"10.1016\/j.biopha.2022.114142","article-title":"Quercetin inclusion complex gels ameliorate radiation-induced brain injury by regulating gut microbiota","volume":"158","author":"Hu","year":"2023","journal-title":"Biomed. Pharmacother."},{"key":"B196","doi-asserted-by":"publisher","first-page":"118425","DOI":"10.1016\/j.jep.2024.118425","article-title":"Novel mechanisms of Anshen Dingzhi prescription against PTSD: Inhibiting DCC to modulate synaptic function and inflammatory responses","volume":"333","author":"Hu","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"B197","doi-asserted-by":"publisher","first-page":"1900752","DOI":"10.1002\/advs.201900752","article-title":"Gut microbiota changes in patients with bipolar depression","volume":"6","author":"Hu","year":"2019","journal-title":"Adv. Sci."},{"key":"B198","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/s40001-022-00691-2","article-title":"Ischemic stroke and intestinal flora: an insight into brain-gut axis","volume":"27","author":"Hu","year":"2022","journal-title":"Eur. J. Med. Res."},{"key":"B199","doi-asserted-by":"publisher","first-page":"eadr8243","DOI":"10.1126\/sciadv.adr8243","article-title":"Microplastics in the bloodstream can induce cerebral thrombosis by causing cell obstruction and lead to neurobehavioral abnormalities","volume":"11","author":"Huang","year":"2025","journal-title":"Sci. Adv."},{"key":"B200","doi-asserted-by":"publisher","first-page":"e16163","DOI":"10.1097\/MD.0000000000016163","article-title":"Fecal microbiota transplantation to treat Parkinson's disease with constipation: a case report","volume":"98","author":"Huang","year":"2019","journal-title":"Medicine"},{"key":"B201","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1001\/archneurol.2011.235","article-title":"Effects of age and amyloid deposition on A\u03b2 dynamics in the human central nervous system","volume":"69","author":"Huang","year":"2012","journal-title":"Arch. Neurol."},{"key":"B202","doi-asserted-by":"publisher","first-page":"3329","DOI":"10.2147\/NDT.S188340","article-title":"Possible association of Firmicutes in the gut microbiota of patients with major depressive disorder","volume":"14","author":"Huang","year":"2018","journal-title":"NDT"},{"key":"B203","doi-asserted-by":"publisher","first-page":"992","DOI":"10.1016\/j.biopsych.2023.10.008","article-title":"Depression in Alzheimer's disease: epidemiology, mechanisms, and treatment","volume":"95","author":"Huang","year":"2024","journal-title":"Biol. Psychiatry"},{"key":"B204","doi-asserted-by":"publisher","first-page":"107716","DOI":"10.1016\/j.celrep.2020.107716","article-title":"Analysis of genetically regulated gene expression identifies a prefrontal PTSD Gene, SNRNP35, specific to military cohorts","volume":"31","author":"Huckins","year":"2020","journal-title":"Cell Rep."},{"key":"B205","doi-asserted-by":"publisher","first-page":"e0244680","DOI":"10.1371\/journal.pone.0244680","article-title":"Multi-strain probiotics (Hexbio) containing MCP BCMC strains improved constipation and gut motility in Parkinson's disease: a randomised controlled trial","volume":"15","author":"Ibrahim","year":"2020","journal-title":"PLoS ONE"},{"key":"B206","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s10020-024-00986-6","article-title":"Chronic inflammation in post-acute sequelae of COVID-19 modulates gut microbiome: a review of literature on COVID-19 sequelae and gut dysbiosis","volume":"31","author":"Iqbal","year":"2025","journal-title":"Mol. Med."},{"key":"B207","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.3389\/fneur.2019.01245","article-title":"Diet in Parkinson's disease: critical role for the microbiome","volume":"10","author":"Jackson","year":"2019","journal-title":"Front. Neurol."},{"key":"B208","doi-asserted-by":"publisher","first-page":"100815","DOI":"10.1016\/j.yfrne.2019.100815","article-title":"You've got male: Sex and the microbiota-gut-brain axis across the lifespan","volume":"56","author":"Jaggar","year":"2020","journal-title":"Front. Neuroendocrinol."},{"key":"B209","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.1080\/13854046.2020.1730975","article-title":"PTSD, but not history of mTBI, is associated with altered myelin in combat-exposed Iraq and Afghanistan Veterans","volume":"34","author":"Jak","year":"2020","journal-title":"Clin. Neuropsychol."},{"key":"B210","doi-asserted-by":"publisher","first-page":"12015","DOI":"10.1038\/ncomms12015","article-title":"Alterations of the human gut microbiome in multiple sclerosis","volume":"7","author":"Jangi","year":"2016","journal-title":"Nat. Commun."},{"key":"B211","doi-asserted-by":"publisher","first-page":"4693","DOI":"10.1021\/bi00069a001","article-title":"The carboxy terminus of the.beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease","volume":"32","author":"Jarrett","year":"1993","journal-title":"Biochemistry"},{"key":"B212","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1186\/s43045-023-00315-3","article-title":"Epidemiology of anxiety disorders: global burden and sociodemographic associations","volume":"30","author":"Javaid","year":"2023","journal-title":"Middle East Curr. Psychiatry"},{"key":"B213","doi-asserted-by":"publisher","first-page":"56","DOI":"10.3390\/nu8010056","article-title":"Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis","volume":"8","author":"Jenkins","year":"2016","journal-title":"Nutrients"},{"key":"B214","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/1710-1492-10-43","article-title":"Patients with posttraumatic stress disorder exhibit an altered phenotype of regulatory T cells","volume":"10","author":"Jergovi\u0107","year":"2014","journal-title":"All. Asth. Clin. Immun."},{"key":"B215","doi-asserted-by":"publisher","first-page":"2895","DOI":"10.1039\/D3FO03897A","article-title":"Neuroprotective effects of probiotics on anxiety- and depression-like disorders in stressed mice by modulating tryptophan metabolism and the gut microbiota","volume":"15","author":"Jia","year":"2024","journal-title":"Food Funct."},{"key":"B216","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.bbi.2015.03.016","article-title":"Altered fecal microbiota composition in patients with major depressive disorder","volume":"48","author":"Jiang","year":"2015","journal-title":"Brain Behav. Immun."},{"key":"B217","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.jpsychires.2018.07.007","article-title":"Altered gut microbiota profile in patients with generalized anxiety disorder","volume":"104","author":"Jiang","year":"2018","journal-title":"J. Psychiatr. Res."},{"key":"B218","doi-asserted-by":"publisher","first-page":"162101","DOI":"10.1016\/j.scitotenv.2023.162101","article-title":"Dysregulation of the microbiota-brain axis during long-term exposure to polystyrene nanoplastics in rats and the protective role of dihydrocaffeic acid","volume":"874","author":"Jiang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"B219","doi-asserted-by":"publisher","first-page":"166003","DOI":"10.1016\/j.scitotenv.2023.166003","article-title":"Simulated gastrointestinal digestion of polylactic acid (PLA) biodegradable microplastics and their interaction with the gut microbiota","volume":"902","author":"Jim\u00e9nez-Arroyo","year":"2023","journal-title":"Sci. Total Environ."},{"key":"B220","doi-asserted-by":"publisher","first-page":"117155","DOI":"10.1016\/j.trac.2023.117155","article-title":"Recent review on selected xenobiotics and their impacts on gut microbiome and metabolome","volume":"166","author":"Jin","year":"2023","journal-title":"Trends Anal. Chem."},{"key":"B221","doi-asserted-by":"publisher","first-page":"l6217","DOI":"10.1136\/bmj.l6217","article-title":"Cognitive symptoms of Alzheimer's disease: clinical management and prevention","volume":"367","author":"Joe","year":"2019","journal-title":"BMJ"},{"key":"B222","doi-asserted-by":"publisher","first-page":"8302","DOI":"10.1038\/s41598-021-87865-w","article-title":"Anxiolytic effects of a galacto-oligosaccharides prebiotic in healthy females (18\u201325 years) with corresponding changes in gut bacterial composition","volume":"11","author":"Johnstone","year":"2021","journal-title":"Sci. Rep."},{"key":"B223","doi-asserted-by":"publisher","first-page":"15529","DOI":"10.1038\/s41598-023-42690-1","article-title":"Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice","volume":"13","author":"Joo","year":"2023","journal-title":"Sci. Rep."},{"key":"B224","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.3390\/nu16111545","article-title":"A narrative review on gut microbiome disturbances and microbial preparations in myalgic encephalomyelitis\/chronic fatigue syndrome: implications for long COVID","volume":"16","author":"Jurek","year":"2024","journal-title":"Nutrients"},{"key":"B225","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1126\/science.1180962","article-title":"Amyloid-\u03b2 dynamics are regulated by orexin and the sleep-wake cycle","volume":"326","author":"Kang","year":"2009","journal-title":"Science"},{"key":"B226","doi-asserted-by":"publisher","first-page":"2310","DOI":"10.3390\/microorganisms9112310","article-title":"The potential utility of prebiotics to modulate Alzheimer's disease: a review of the evidence","volume":"9","author":"Kang","year":"2021","journal-title":"Microorganisms"},{"key":"B227","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1038\/s41398-018-0116-8","article-title":"Prebiotic attenuation of olanzapine-induced weight gain in rats: analysis of central and peripheral biomarkers and gut microbiota","volume":"8","author":"Kao","year":"2018","journal-title":"Transl. Psychiatry"},{"key":"B228","doi-asserted-by":"publisher","first-page":"1118529","DOI":"10.3389\/fmicb.2023.1118529","article-title":"Communication of gut microbiota and brain via immune and neuroendocrine signaling","volume":"14","author":"Kasarello","year":"2023","journal-title":"Front. Microbiol."},{"key":"B229","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1038\/s41398-022-02094-7","article-title":"The role of the immune system in posttraumatic stress disorder","volume":"12","author":"Katrinli","year":"2022","journal-title":"Transl. Psychiatry"},{"key":"B230","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1016\/j.clnu.2018.04.010","article-title":"Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: a randomized clinical trial","volume":"38","author":"Kazemi","year":"2019","journal-title":"Clin. Nutr."},{"key":"B231","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1038\/s44220-023-00145-6","article-title":"Association of probable post-traumatic stress disorder with dietary pattern and gut microbiome in a cohort of women","volume":"1","author":"Ke","year":"2023","journal-title":"Nat. Ment. Health"},{"key":"B232","doi-asserted-by":"publisher","first-page":"31858","DOI":"10.3402\/ejpt.v7.31858","article-title":"PTSD: from neurobiology to pharmacological treatments","volume":"7","author":"Kelmendi","year":"2016","journal-title":"Eur. J. Psychotraumatol."},{"key":"B233","doi-asserted-by":"publisher","first-page":"20503121241260000","DOI":"10.1177\/20503121241260000","article-title":"The relationship between post-traumatic stress disorder and gastrointestinal disease in United States Military Veterans","volume":"12","author":"Kent","year":"2024","journal-title":"SAGE Open Med."},{"key":"B234","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1002\/mds.26307","article-title":"Colonic bacterial composition in Parkinson's disease","volume":"30","author":"Keshavarzian","year":"2015","journal-title":"Mov. Disord."},{"key":"B235","doi-asserted-by":"publisher","first-page":"118627","DOI":"10.1016\/j.lfs.2020.118627","article-title":"Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease","volume":"264","author":"Kesika","year":"2021","journal-title":"Life Sci."},{"key":"B236","doi-asserted-by":"publisher","first-page":"115246","DOI":"10.1016\/j.bbr.2024.115246","article-title":"Probiotic treatment improves post-traumatic stress disorder outcomes in mice","volume":"476","author":"Khan","year":"2025","journal-title":"Behav. Brain Res."},{"key":"B237","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1007\/s43440-023-00489-x","article-title":"Proton pump inhibitor-induced gut dysbiosis and immunomodulation: current knowledge and potential restoration by probiotics","volume":"75","author":"Kiecka","year":"2023","journal-title":"Pharmacol. Rep."},{"key":"B238","doi-asserted-by":"publisher","first-page":"709091","DOI":"10.3389\/fnagi.2021.709091","article-title":"Administration of Bifidobacterium bifidum BGN4 and Bifidobacterium longum BORI improves cognitive and memory function in the mouse model of Alzheimer's disease","volume":"13","author":"Kim","year":"2021","journal-title":"Front. Aging Neurosci."},{"key":"B239","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/j.bbi.2021.09.002","article-title":"Transplantation of gut microbiota derived from Alzheimer's disease mouse model impairs memory function and neurogenesis in C57BL\/6 mice","volume":"98","author":"Kim","year":"2021","journal-title":"Brain Behav. Immun."},{"key":"B240","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1016\/j.neuron.2019.05.035","article-title":"Transneuronal propagation of pathologic \u03b1-synuclein from the gut to the brain models Parkinson's disease","volume":"103","author":"Kim","year":"2019","journal-title":"Neuron"},{"key":"B241","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.jad.2023.04.003","article-title":"Association between gut microbiota and anxiety symptoms: A large population-based study examining sex differences","volume":"333","author":"Kim","year":"2023","journal-title":"J. Affect. Disord."},{"key":"B242","doi-asserted-by":"publisher","first-page":"232","DOI":"10.3390\/biom9060232","article-title":"The biosynthesis, signaling, and neurological functions of bile acids","volume":"9","author":"Kiriyama","year":"2019","journal-title":"Biomolecules"},{"key":"B243","doi-asserted-by":"publisher","first-page":"19933","DOI":"10.1038\/s41598-020-77105-y","article-title":"Deep phenotyping of myalgic encephalomyelitis\/chronic fatigue syndrome in Japanese population","volume":"10","author":"Kitami","year":"2020","journal-title":"Sci. Rep."},{"key":"B244","doi-asserted-by":"publisher","first-page":"e02177","DOI":"10.1002\/brb3.2177","article-title":"Gut microbiota variations in patients diagnosed with major depressive disorder\u2014A systematic review","volume":"11","author":"Knudsen","year":"2021","journal-title":"Brain Behav."},{"key":"B245","doi-asserted-by":"publisher","first-page":"13510","DOI":"10.1038\/s41598-017-13368-2","article-title":"Therapeutic potential of Bifidobacterium breve strain A1 for preventing cognitive impairment in Alzheimer's disease","volume":"7","author":"Kobayashi","year":"2017","journal-title":"Sci. Rep."},{"key":"B246","doi-asserted-by":"publisher","first-page":"628741","DOI":"10.3389\/fimmu.2021.628741","article-title":"The gut microbiome in myalgic encephalomyelitis (ME)\/chronic fatigue syndrome (CFS)","volume":"12","author":"K\u00f6nig","year":"2021","journal-title":"Front. Immunol."},{"key":"B247","doi-asserted-by":"publisher","first-page":"1580435","DOI":"10.3389\/fnana.2025.1580435","article-title":"Altered dendritic morphology of MEC II pyramidal and stellate cells in Rett syndrome mice","volume":"19","author":"Krishnan","year":"2025","journal-title":"Front. Neuroanat."},{"key":"B248","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s00401-016-1653-y","article-title":"An updated histological classification system for multiple sclerosis lesions","volume":"133","author":"Kuhlmann","year":"2017","journal-title":"Acta Neuropathol."},{"key":"B249","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1002\/mus.27567","article-title":"Amyotrophic lateral sclerosis mimics","volume":"66","author":"Kwan","year":"2022","journal-title":"Muscle Nerve"},{"key":"B250","doi-asserted-by":"publisher","first-page":"e300","DOI":"10.1002\/cpz1.300","article-title":"Experimental autoimmune encephalomyelitis in the mouse","volume":"1","author":"Laaker","year":"2021","journal-title":"Curr. Protoc."},{"key":"B251","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1016\/j.genhosppsych.2025.03.012","article-title":"Analysis of gut microbiota and depression and anxiety: Mendelian randomization from three datasets","volume":"94","author":"Lai","year":"2025","journal-title":"Gen. Hosp. Psychiatry"},{"key":"B252","doi-asserted-by":"publisher","first-page":"25777","DOI":"10.1038\/srep25777","article-title":"Natural lecithin promotes neural network complexity and activity","volume":"6","author":"Latifi","year":"2016","journal-title":"Sci. Rep."},{"key":"B253","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.bbi.2022.11.004","article-title":"Gut microbiota alterations promote traumatic stress susceptibility associated with p-cresol-induced dopaminergic dysfunctions","volume":"107","author":"Laudani","year":"2023","journal-title":"Brain Behav. Immun."},{"key":"B254","doi-asserted-by":"publisher","first-page":"e9009","DOI":"10.1371\/journal.pone.0009009","article-title":"A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells","volume":"5","author":"Lavasani","year":"2010","journal-title":"PLoS ONE"},{"key":"B255","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1038\/s41398-019-0653-9","article-title":"Early exposure to antibiotic drugs and risk for psychiatric disorders: a population-based study","volume":"9","author":"Lavebratt","year":"2019","journal-title":"Transl. Psychiatry"},{"key":"B256","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1177\/0706743716635535","article-title":"Posttraumatic stress disorder: does the gut microbiome hold the key?","volume":"61","author":"Leclercq","year":"2016","journal-title":"Can. J. Psychiatry"},{"key":"B257","doi-asserted-by":"publisher","first-page":"2190","DOI":"10.1016\/j.cell.2025.03.005","article-title":"Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety","volume":"188","author":"Lee","year":"2025","journal-title":"Cell"},{"key":"B258","doi-asserted-by":"publisher","first-page":"11814","DOI":"10.1038\/s41598-019-48342-7","article-title":"Suppression of gut dysbiosis by Bifidobacterium longum alleviates cognitive decline in 5XFAD transgenic and aged mice","volume":"9","author":"Lee","year":"","journal-title":"Sci. Rep."},{"key":"B259","doi-asserted-by":"publisher","first-page":"2660","DOI":"10.3390\/nu13082660","article-title":"Effects of probiotic NVP-1704 on mental health and sleep in healthy adults: an 8-week randomized, double-blind, placebo-controlled trial","volume":"13","author":"Lee","year":"2021","journal-title":"Nutrients"},{"key":"B260","doi-asserted-by":"publisher","first-page":"1530","DOI":"10.4103\/1673-5374.255974","article-title":"Sodium butyrate prevents radiation-induced cognitive impairment by restoring pCREB\/BDNF expression","volume":"14","author":"Lee","year":"","journal-title":"Neural. Regen. Res."},{"key":"B261","doi-asserted-by":"publisher","first-page":"115992","DOI":"10.1016\/j.psychres.2024.115992","article-title":"Antibiotic exposure and depression incidence: a cohort study of the Korean population","volume":"339","author":"Lee","year":"2024","journal-title":"Psychiatry Res."},{"key":"B262","doi-asserted-by":"publisher","first-page":"15","DOI":"10.4093\/dmj.2021.0280","article-title":"Insulin resistance: from mechanisms to therapeutic strategies","volume":"46","author":"Lee","year":"2022","journal-title":"Diabetes Metab. J."},{"key":"B263","doi-asserted-by":"publisher","first-page":"e0245038","DOI":"10.1371\/journal.pone.0245038","article-title":"Microbiome and ischemic stroke: a systematic review","volume":"16","author":"Lee","year":"2021","journal-title":"PLoS ONE"},{"key":"B264","doi-asserted-by":"publisher","first-page":"104149","DOI":"10.1016\/j.etap.2023.104149","article-title":"Low-dose glyphosate exposure alters gut microbiota composition and modulates gut homeostasis","volume":"100","author":"Lehman","year":"2023","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"B265","doi-asserted-by":"publisher","first-page":"917575","DOI":"10.3389\/fcell.2022.917575","article-title":"Considering the role of extracellular matrix molecules, in particular reelin, in granule cell dispersion related to temporal lobe epilepsy","volume":"10","author":"Leifeld","year":"2022","journal-title":"Front. Cell. Dev. Biol."},{"key":"B266","doi-asserted-by":"publisher","first-page":"124556","DOI":"10.1016\/j.jhazmat.2020.124556","article-title":"Classification of the glyphosate target enzyme (5-enolpyruvylshikimate-3-phosphate synthase) for assessing sensitivity of organisms to the herbicide","volume":"408","author":"Leino","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"B267","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1016\/j.jalz.2019.07.002","article-title":"Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota","volume":"15","author":"Li","year":"2019","journal-title":"Alzheimers. Dement."},{"key":"B268","doi-asserted-by":"publisher","first-page":"108543","DOI":"10.1016\/j.envint.2024.108543","article-title":"Polystyrene microplastics induce anxiety via HRAS derived PERK-NF-\u03baB pathway","volume":"185","author":"Li","year":"2024","journal-title":"Environ. Int."},{"key":"B269","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.bbi.2023.10.014","article-title":"Sterile soil mitigates the intergenerational loss of gut microbial diversity and anxiety-like behavior induced by antibiotics in mice","volume":"115","author":"Li","year":"2024","journal-title":"Brain Behav. Immun."},{"key":"B270","doi-asserted-by":"publisher","first-page":"1185375","DOI":"10.3389\/fneur.2023.1185375","article-title":"The role of the microbiota-gut-brain axis and intestinal microbiome dysregulation in Parkinson's disease","volume":"14","author":"Li","year":"2023","journal-title":"Front. Neurol."},{"key":"B271","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s10068-024-01698-7","article-title":"Dietary herbs that interact with gut microbiota: roles as anti-stroke agents","volume":"34","author":"Li","year":"2025","journal-title":"Food Sci. Biotechnol."},{"key":"B272","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1089\/neur.2024.0011","article-title":"Gut microbial composition is associated with symptom self-report in trauma-exposed Iraq and Afghanistan veterans","volume":"6","author":"Li","year":"2025","journal-title":"Neurotrauma Rep."},{"key":"B273","doi-asserted-by":"publisher","first-page":"48","DOI":"10.3390\/nu15010048","article-title":"New insights into the relationship between gut microbiota and radiotherapy for cancer","volume":"15","author":"Li","year":"2022","journal-title":"Nutrients"},{"key":"B274","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.neuron.2014.11.018","article-title":"NF\u03baB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease","volume":"85","author":"Lian","year":"2015","journal-title":"Neuron"},{"key":"B275","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s00213-023-06466-9","article-title":"Frontostriatal circuitry and the tryptophan kynurenine pathway in major psychiatric disorders","volume":"241","author":"Liang","year":"2024","journal-title":"Psychopharmacology"},{"key":"B276","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1038\/nature21029","article-title":"Neurotoxic reactive astrocytes are induced by activated microglia","volume":"541","author":"Liddelow","year":"2017","journal-title":"Nature"},{"key":"B277","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.5665\/sleep.2802","article-title":"Sleep fragmentation and the risk of incident Alzheimer's disease and cognitive decline in older persons","volume":"36","author":"Lim","year":"2013","journal-title":"Sleep"},{"key":"B278","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.parkreldis.2018.05.007","article-title":"Gut microbiota in patients with Parkinson's disease in southern China","volume":"53","author":"Lin","year":"2018","journal-title":"Parkinson. Relat. Disord."},{"key":"B279","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1038\/s41579-022-00681-5","article-title":"Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota","volume":"20","author":"Lindell","year":"2022","journal-title":"Nat. Rev. Microbiol."},{"key":"B280","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s13014-020-01735-9","article-title":"Radiotherapy and the gut microbiome: facts and fiction","volume":"16","author":"Liu","year":"2021","journal-title":"Radiation Oncol."},{"key":"B281","doi-asserted-by":"publisher","first-page":"1721","DOI":"10.3390\/healthcare12171721","article-title":"Estimation of the global disease burden of depression and anxiety between 1990 and 2044: an analysis of the global burden of disease study 2019","volume":"12","author":"Liu","year":"2024","journal-title":"Healthcare"},{"key":"B282","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.3389\/fimmu.2017.01005","article-title":"Role of neuroinflammation in amyotrophic lateral sclerosis: cellular mechanisms and therapeutic implications","volume":"8","author":"Liu","year":"2017","journal-title":"Front. Immunol."},{"key":"B283","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.jns.2017.08.3235","article-title":"Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1","volume":"381","author":"Liu","year":"2017","journal-title":"J. Neurol. Sci."},{"key":"B284","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/j.bbi.2019.05.008","article-title":"Altered microbiomes distinguish Alzheimer's disease from amnestic mild cognitive impairment and health in a Chinese cohort","volume":"80","author":"Liu","year":"2019","journal-title":"Brain Behav. Immun."},{"key":"B285","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/j.bbi.2020.03.026","article-title":"Reductions in anti-inflammatory gut bacteria are associated with depression in a sample of young adults","volume":"88","author":"Liu","year":"2020","journal-title":"Brain Behav. Immun."},{"key":"B286","doi-asserted-by":"publisher","first-page":"103198","DOI":"10.1016\/j.autneu.2024.103198","article-title":"Research progress on pathogenesis of chronic fatigue syndrome and treatment of traditional Chinese and Western medicine","volume":"255","author":"Liu","year":"2024","journal-title":"Auton. Neurosci."},{"key":"B287","doi-asserted-by":"publisher","first-page":"e6865","DOI":"10.1002\/cam4.6865","article-title":"Radiation enteropathy-related depression: a neglectable course of disease by gut bacterial dysbiosis","volume":"13","author":"Liu","year":"2024","journal-title":"Cancer Med."},{"key":"B288","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.neures.2021.04.001","article-title":"Vagotomy and insights into the microbiota-gut-brain axis","volume":"168","author":"Liu","year":"2021","journal-title":"Neurosci. Res."},{"key":"B289","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.cmet.2019.11.001","article-title":"Gut microbiome fermentation determines the efficacy of exercise for diabetes prevention","volume":"31","author":"Liu","year":"2020","journal-title":"Cell Metab."},{"key":"B290","doi-asserted-by":"publisher","first-page":"833365","DOI":"10.3389\/fnagi.2022.833365","article-title":"The effect of long-term or repeated use of antibiotics in children and adolescents on cognitive impairment in middle-aged and older person(s) adults: a cohort study","volume":"14","author":"Liu","year":"2022","journal-title":"Front. Aging Neurosci."},{"key":"B291","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1038\/s41392-024-01743-1","article-title":"Microbiota-gut-brain axis and its therapeutic applications in neurodegenerative diseases","volume":"9","author":"Loh","year":"2024","journal-title":"Sig. Transduct. Target. Ther."},{"key":"B292","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1097\/EDE.0b013e3182944410","article-title":"Mediterranean diet, cognitive function, and dementia: a systematic review","volume":"24","author":"Lourida","year":"2013","journal-title":"Epidemiology"},{"key":"B293","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1186\/s10020-024-00873-0","article-title":"Microbiome in radiotherapy: an emerging approach to enhance treatment efficacy and reduce tissue injury","volume":"30","author":"Lu","year":"2024","journal-title":"Mol. Med."},{"key":"B294","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1002\/jpen.1744","article-title":"Phycocyanin ameliorates radiation-induced acute intestinal toxicity by regulating the effect of the gut microbiota on the TLR4\/Myd88\/NF-\u03baB pathway","volume":"44","author":"Lu","year":"2020","journal-title":"J. Parenteral Enteral Nutr."},{"key":"B295","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1007\/s00415-020-09723-5","article-title":"Gastrointestinal dysfunction in Parkinson's disease","volume":"267","author":"Lubomski","year":"2020","journal-title":"J. Neurol."},{"key":"B296","doi-asserted-by":"publisher","first-page":"875261","DOI":"10.3389\/fnagi.2022.875261","article-title":"The gut microbiome in Parkinson's disease: a longitudinal study of the impacts on disease progression and the use of device-assisted therapies","volume":"14","author":"Lubomski","year":"","journal-title":"Front. Aging Neurosci."},{"key":"B297","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1007\/s00415-021-10657-9","article-title":"The impact of device-assisted therapies on the gut microbiome in Parkinson's disease","volume":"269","author":"Lubomski","year":"","journal-title":"J. Neurol."},{"key":"B298","doi-asserted-by":"publisher","first-page":"118142","DOI":"10.1016\/j.ecoenv.2025.118142","article-title":"Association between microplastics exposure and depressive symptoms in college students","volume":"295","author":"Luo","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"B299","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1667\/RADE-21-00006.1","article-title":"Impact of gut microbiota on radiation-associated cognitive dysfunction and neuroinflammation in mice","volume":"197","author":"Luo","year":"2022","journal-title":"Radiat. Res."},{"key":"B300","doi-asserted-by":"publisher","first-page":"7043","DOI":"10.1038\/s41598-021-86425-6","article-title":"Potential role of microbiome in chronic fatigue syndrome\/myalgic encephalomyelits (CFS\/ME)","volume":"11","author":"Lupo","year":"2021","journal-title":"Sci. Rep."},{"key":"B301","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/S0031-9384(98)00145-0","article-title":"Anxiogenic effect of subclinical bacterial infection in mice in the absence of overt immune activation","volume":"65","author":"Lyte","year":"1998","journal-title":"Physiol. Behav."},{"key":"B302","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.3390\/molecules27041210","article-title":"Amyloidosis in Alzheimer's disease: pathogeny, etiology, and related therapeutic directions","volume":"27","author":"Ma","year":"2022","journal-title":"Molecules"},{"key":"B303","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1038\/s41398-025-03372-w","article-title":"Role of inflammation in depressive and anxiety disorders, affect, and cognition: genetic and non-genetic findings in the lifelines cohort study","volume":"15","author":"Mac Giollabhui","year":"2025","journal-title":"Transl. Psychiatry"},{"key":"B304","doi-asserted-by":"publisher","first-page":"e459","DOI":"10.1212\/NXI.0000000000000459","article-title":"Fecal microbiota transplantation associated with 10 years of stability in a patient with SPMS","volume":"5","author":"Makkawi","year":"2018","journal-title":"Neurol. Neuroimmunol. Neuroinflamm."},{"key":"B305","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.euroneuro.2021.11.009","article-title":"Exploring the relationship between the gut microbiome and mental health outcomes in a posttraumatic stress disorder cohort relative to trauma-exposed controls","volume":"56","author":"Malan-Muller","year":"2022","journal-title":"Europ. Neuropsychopharmacol."},{"key":"B306","doi-asserted-by":"publisher","first-page":"2299","DOI":"10.1016\/S0140-6736(18)31948-2","article-title":"Depression","volume":"392","author":"Malhi","year":"2018","journal-title":"Lancet"},{"key":"B307","doi-asserted-by":"publisher","first-page":"102","DOI":"10.3389\/fonc.2012.00102","article-title":"Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells","volume":"2","author":"Manda","year":"2012","journal-title":"Front. Oncol."},{"key":"B308","doi-asserted-by":"publisher","first-page":"1486","DOI":"10.1053\/j.gastro.2020.10.066","article-title":"The microbiota-gut-brain axis: from motility to mood","volume":"160","author":"Margolis","year":"2021","journal-title":"Gastroenterology"},{"key":"B309","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/s41572-023-00454-1","article-title":"Major depressive disorder","volume":"9","author":"Marx","year":"2023","journal-title":"Nat. Rev. Dis. Primers"},{"key":"B310","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.3390\/antiox12071423","article-title":"Examining the mechanisms behind exercise's multifaceted impacts on body composition, cognition, and the gut microbiome in cancer survivors: exploring the links to oxidative stress and inflammation","volume":"12","author":"Matei","year":"2023","journal-title":"Antioxidants"},{"key":"B311","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1271\/bbb.70474","article-title":"Voluntary running exercise alters microbiota composition and increases n-butyrate concentration in the rat cecum","volume":"72","author":"Matsumoto","year":"2008","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"B312","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1523\/JNEUROSCI.0733-19.2019","article-title":"Revisiting the stress concept: implications for affective disorders","volume":"40","author":"McEwen","year":"2020","journal-title":"J. Neurosci."},{"key":"B313","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1080\/1028415X.2019.1612555","article-title":"Characterizing the gut microbiota in adults with bipolar disorder: a pilot study","volume":"24","author":"McIntyre","year":"2021","journal-title":"Nutr. Neurosci."},{"key":"B314","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1001\/jamapsychiatry.2019.1119","article-title":"Genetic variants associated with anxiety and stress-related disorders: a genome-wide association study and mouse-model study","volume":"76","author":"Meier","year":"2019","journal-title":"JAMA Psychiatry"},{"key":"B315","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1111\/ene.14644","article-title":"Gut microbiota and metabolome distinctive features in Parkinson disease: Focus on levodopa and levodopa-carbidopa intrajejunal gel","volume":"28","author":"Melis","year":"2021","journal-title":"Euro. J. Neurol."},{"key":"B316","doi-asserted-by":"publisher","first-page":"131","DOI":"10.3389\/fnins.2020.00131","article-title":"Relationship between exercise and Alzheimer's disease: a narrative literature review","volume":"14","author":"Meng","year":"2020","journal-title":"Front. Neurosci."},{"key":"B317","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1007\/s40263-024-01073-4","article-title":"The gut microbiota in Parkinson disease: interactions with drugs and potential for therapeutic applications","volume":"38","author":"Menozzi","year":"2024","journal-title":"CNS Drugs"},{"key":"B318","doi-asserted-by":"publisher","first-page":"017005","DOI":"10.1289\/EHP6990","article-title":"Use of shotgun metagenomics and metabolomics to evaluate the impact of glyphosate or roundup MON 52276 on the gut microbiota and serum metabolome of sprague-dawley rats","volume":"129","author":"Mesnage","year":"2021","journal-title":"Environ. Health Perspect."},{"key":"B319","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.3389\/fimmu.2019.01374","article-title":"Manipulation of gut microbiota influences immune responses, axon preservation, and motor disability in a model of progressive multiple sclerosis","volume":"10","author":"Mestre","year":"2019","journal-title":"Front. Immunol."},{"key":"B320","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.4103\/1673-5374.193234","article-title":"Neurofibrillary tangles in Alzheimer\u2032s disease: elucidation of the molecular mechanism by immunohistochemistry and tau protein phospho-proteomics","volume":"11","author":"Metaxas","year":"2016","journal-title":"Neural. Regen. Res."},{"key":"B321","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.biopsych.2015.01.005","article-title":"Diagnostic biomarkers for posttraumatic stress disorder: promising horizons from translational neuroscience research","volume":"78","author":"Michopoulos","year":"2015","journal-title":"Biol. Psychiatry"},{"key":"B322","doi-asserted-by":"publisher","first-page":"10411","DOI":"10.1038\/s41598-017-11047-w","article-title":"Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE\/PS1\u0394E9 murine model of Alzheimer's disease","volume":"7","author":"Minter","year":"2017","journal-title":"Sci. Rep."},{"key":"B323","doi-asserted-by":"publisher","first-page":"30028","DOI":"10.1038\/srep30028","article-title":"Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease","volume":"6","author":"Minter","year":"2016","journal-title":"Sci. Rep."},{"key":"B324","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1056\/NEJM198602273140921","article-title":"Possible familial association of multiple sclerosis and inflammatory bowel disease","volume":"314","author":"Minuk","year":"1986","journal-title":"N. Engl. J. Med."},{"key":"B325","doi-asserted-by":"publisher","first-page":"1526488","DOI":"10.3389\/fpsyt.2024.1526488","article-title":"Emulating a randomized clinical trial with real-world data to evaluate the effect of antidepressant use in PTSD patients with high suicide risk","volume":"15","author":"Miranda","year":"2025","journal-title":"Front. Psychiatry"},{"key":"B326","doi-asserted-by":"publisher","first-page":"e14724","DOI":"10.1111\/ijcp.14724","article-title":"Effect of probiotics supplementation on disease progression, depression, general health, and anthropometric measurements in relapsing-remitting multiple sclerosis patients: a systematic review and meta-analysis of clinical trials","volume":"75","author":"Mirashrafi","year":"2021","journal-title":"Int. J. Clin. Pract."},{"key":"B327","doi-asserted-by":"publisher","first-page":"111661","DOI":"10.1016\/j.biopha.2021.111661","article-title":"Role of microbiota-derived short-chain fatty acids in nervous system disorders","volume":"139","author":"Mirzaei","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"B328","doi-asserted-by":"publisher","first-page":"e0137429","DOI":"10.1371\/journal.pone.0137429","article-title":"Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to Clostridia XIVa and IV clusters","volume":"10","author":"Miyake","year":"2015","journal-title":"PLoS ONE"},{"key":"B329","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1097\/WNF.0000000000000299","article-title":"Clostridium butyricum MIYAIRI 588 as adjunctive therapy for treatment-resistant major depressive disorder: a prospective open-label trial","volume":"41","author":"Miyaoka","year":"2018","journal-title":"Clin. Neuropharm."},{"key":"B330","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s12017-020-08625-z","article-title":"Bile acids: a communication channel in the gut-brain axis","volume":"23","author":"Monteiro-Cardoso","year":"2021","journal-title":"Neuromol. Med."},{"key":"B331","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1001\/jamapsychiatry.2022.0645","article-title":"Cerebrospinal fluid biomarkers in patients with unipolar depression compared with healthy control individuals: a systematic review and meta-analysis","volume":"79","author":"Mousten","year":"2022","journal-title":"JAMA Psychiatry"},{"key":"B332","doi-asserted-by":"publisher","first-page":"461","DOI":"10.3233\/JAD-210608","article-title":"Bile acids as key modulators of the brain-gut-microbiota axis in Alzheimer's disease","volume":"84","author":"Mulak","year":"2021","journal-title":"JAD"},{"key":"B333","doi-asserted-by":"publisher","first-page":"e148","DOI":"10.1038\/emm.2014.121","article-title":"Sleep, circadian rhythms, and the pathogenesis of Alzheimer disease","volume":"47","author":"Musiek","year":"2015","journal-title":"Exp. Mol. Med."},{"key":"B334","doi-asserted-by":"publisher","first-page":"1589287","DOI":"10.3389\/fnana.2025.1589287","article-title":"Selective vulnerability of stellate cells to gut dysbiosis: neuroanatomical changes in the medial entorhinal cortex","volume":"19","author":"Mydeen","year":"2025","journal-title":"Front. Neuroanat."},{"key":"B335","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1007\/s40520-024-02729-3","article-title":"Bile acid profile associated with CSF and PET biomarkers in Alzheimer's disease","volume":"36","author":"Nabizadeh","year":"2024","journal-title":"Aging Clin. Exp. Res."},{"key":"B336","doi-asserted-by":"publisher","first-page":"699","DOI":"10.12688\/f1000research.18992.1","article-title":"Gut microbiome-Mediterranean diet interactions in improving host health","volume":"8","author":"Nagpal","year":"2019","journal-title":"F1000Research"},{"key":"B337","doi-asserted-by":"publisher","first-page":"1557961","DOI":"10.3389\/fnana.2025.1557961","article-title":"Antibiotics-induced dysbiosis impacts dendritic morphology of adult mouse cortical interneurons","volume":"19","author":"Nakhal","year":"","journal-title":"Front. Neuroanat."},{"key":"B338","doi-asserted-by":"publisher","first-page":"1909","DOI":"10.3390\/ijms26051909","article-title":"Early-life stress caused by maternal deprivation impacts dendritic morphology of adult male mouse neocortical interneurons","volume":"26","author":"Nakhal","year":"","journal-title":"Int. J. Mol. Sci."},{"key":"B339","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.3390\/life14101234","article-title":"The microbiota-gut-brain axis and neurological disorders: a comprehensive review","volume":"14","author":"Nakhal","year":"2024","journal-title":"Life"},{"key":"B340","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1111\/nmo.12378","article-title":"Correlation between the human fecal microbiota and depression","volume":"26","author":"Naseribafrouei","year":"2014","journal-title":"Neurogastroenterol. Motil."},{"key":"B341","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1111\/j.1365-2982.2010.01620.x","article-title":"Reduced anxiety-like behavior and central neurochemical change in germ-free mice","volume":"23","author":"Neufeld","year":"2011","journal-title":"Neurogastroenterol. Motil."},{"key":"B342","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/978-1-0716-3662-6_27","article-title":"Fecal microbiota transplantation in amyotrophic lateral sclerosis: clinical protocol and evaluation of microbiota immunity axis","volume":"2761","author":"Niccolai","year":"2024","journal-title":"Methods Mol. Biol."},{"key":"B343","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/1742-2094-5-13","article-title":"Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid","volume":"5","author":"Nichol","year":"2008","journal-title":"J. Neuroinflamm."},{"key":"B344","doi-asserted-by":"publisher","first-page":"1370","DOI":"10.1001\/jama.2023.18588","article-title":"Diagnosis and treatment of bipolar disorder: a review","volume":"330","author":"Nierenberg","year":"2023","journal-title":"JAMA"},{"key":"B345","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1038\/s41591-024-03453-1","article-title":"Bioaccumulation of microplastics in decedent human brains","volume":"31","author":"Nihart","year":"2025","journal-title":"Nat. Med."},{"key":"B346","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5402\/2012\/376023","article-title":"Anorectal dysfunction in multiple sclerosis: a systematic review","volume":"2012","author":"Nusrat","year":"2012","journal-title":"ISRN Neurol."},{"key":"B347","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1002\/mds.27115","article-title":"Past, present, and future of Parkinson's disease: a special essay on the 200th Anniversary of the Shaking Palsy","volume":"32","author":"Obeso","year":"2017","journal-title":"Mov. Disord."},{"key":"B348","doi-asserted-by":"publisher","first-page":"784","DOI":"10.3390\/microorganisms8050784","article-title":"The role of the microbiota-gut-brain axis and antibiotics in ALS and neurodegenerative diseases","volume":"8","author":"Obrenovich","year":"2020","journal-title":"Microorganisms"},{"key":"B349","doi-asserted-by":"publisher","first-page":"6041","DOI":"10.4049\/jimmunol.0900747","article-title":"Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis","volume":"183","author":"Ochoa-Rep\u00e1raz","year":"2009","journal-title":"J. Immunol."},{"key":"B350","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000542696","article-title":"The saNeuroGut initiative: investigating the gut microbiome and symptoms of anxiety, depression, and posttraumatic stress","volume":"32","author":"O'Hare","year":"2024","journal-title":"Neuroimmunomodulation"},{"key":"B351","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/S1474-4422(13)70293-X","article-title":"Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy study","volume":"13","author":"Olanow","year":"2014","journal-title":"Lancet Neurol."},{"key":"B352","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1016\/j.neuroscience.2014.07.054","article-title":"Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats","volume":"277","author":"O'Mahony","year":"2014","journal-title":"Neuroscience"},{"key":"B353","doi-asserted-by":"publisher","first-page":"112246","DOI":"10.1016\/j.forsciint.2024.112246","article-title":"Presence of microplastics in human stomachs","volume":"364","author":"\u00d6zsoy","year":"2024","journal-title":"Forensic Sci. Int."},{"key":"B354","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/bdi.12682","article-title":"A step ahead: exploring the gut microbiota in inpatients with bipolar disorder during a depressive episode","volume":"21","author":"Painold","year":"2019","journal-title":"Bipolar Disord."},{"key":"B355","doi-asserted-by":"publisher","first-page":"574529","DOI":"10.3389\/fneur.2021.574529","article-title":"Effect of levodopa initiation on the gut microbiota in Parkinson's disease","volume":"12","author":"Palacios","year":"2021","journal-title":"Front. Neurol."},{"key":"B356","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.3233\/JAD-170764","article-title":"Geographical distribution and diversity of gut microbial NADH: ubiquinone oxidoreductase sequence associated with Alzheimer's disease","volume":"61","author":"Paley","year":"2018","journal-title":"J. Alzheimer. Dis."},{"key":"B357","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.clim.2015.05.014","article-title":"Immune\u2013microbiota interactions in health and disease","volume":"159","author":"Palm","year":"2015","journal-title":"Clin. Immunol."},{"key":"B358","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.molmed.2023.07.002","article-title":"The global human gut microbiome: genes, lifestyles, and diet","volume":"29","author":"Parizadeh","year":"2023","journal-title":"Trends Mol. Med."},{"key":"B359","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1080\/03007995.2021.1957807","article-title":"Cognitive function improvement after fecal microbiota transplantation in Alzheimer's dementia patient: a case report","volume":"37","author":"Park","year":"2021","journal-title":"Curr. Med. Res. Opin."},{"key":"B360","doi-asserted-by":"publisher","first-page":"509","DOI":"10.3390\/diagnostics11030509","article-title":"Amyotrophic lateral sclerosis and frontotemporal lobar degenerations: similarities in genetic background","volume":"11","author":"Parobkova","year":"2021","journal-title":"Diagnostics"},{"key":"B361","doi-asserted-by":"publisher","first-page":"85","DOI":"10.3390\/nu13010085","article-title":"From preclinical stroke models to humans: polyphenols in the prevention and treatment of stroke","volume":"13","author":"Parrella","year":"2020","journal-title":"Nutrients"},{"key":"B362","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1007\/s12223-022-00977-2","article-title":"Exploring the multifactorial aspects of gut microbiome in Parkinson's disease","volume":"67","author":"Pavan","year":"2022","journal-title":"Folia Microbiol."},{"key":"B363","doi-asserted-by":"publisher","first-page":"1788","DOI":"10.1161\/STROKEAHA.121.036800","article-title":"Gut microbiota and their metabolites in stroke: a double-edged sword","volume":"53","author":"Peh","year":"2022","journal-title":"Stroke"},{"key":"B364","doi-asserted-by":"publisher","first-page":"114474","DOI":"10.1016\/j.fct.2024.114474","article-title":"Simulated gastrointestinal digestion of two different sources of biodegradable microplastics and the influence on gut microbiota","volume":"185","author":"Peng","year":"2024","journal-title":"Food Chem. Toxicol."},{"key":"B365","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1186\/1741-7015-11-129","article-title":"Understanding the somatic consequences of depression: biological mechanisms and the role of depression symptom profile","volume":"11","author":"Penninx","year":"2013","journal-title":"BMC Med."},{"key":"B366","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1007\/s00127-013-0762-3","article-title":"Determinants of the development of post-traumatic stress disorder, in the general population","volume":"49","author":"Perrin","year":"2014","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"key":"B367","doi-asserted-by":"publisher","first-page":"1349883","DOI":"10.3389\/fimmu.2024.1349883","article-title":"Exploring the interplay between posttraumatic stress disorder, gut microbiota, and inflammatory biomarkers: a comprehensive meta-analysis","volume":"15","author":"Petakh","year":"2024","journal-title":"Front. Immunol."},{"key":"B368","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/S1474-4422(03)00307-7","article-title":"Gastrointestinal dysfunction in Parkinson's disease","volume":"2","author":"Pfeiffer","year":"2003","journal-title":"Lancet Neurol."},{"key":"B369","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s100720170061","article-title":"Reduced L -dopa absorption and increased clinical fluctuations in Helicobacter pylori-infected Parkinson's disease patients","volume":"22","author":"Pierantozzi","year":"2001","journal-title":"Neurol. Sci."},{"key":"B370","doi-asserted-by":"publisher","first-page":"331","DOI":"10.3390\/antibiotics11030331","article-title":"The interplay among radiation therapy, antibiotics and the microbiota: impact on cancer treatment outcomes","volume":"11","author":"Poonacha","year":"2022","journal-title":"Antibiotics"},{"key":"B371","doi-asserted-by":"publisher","first-page":"25","DOI":"10.3389\/fnmol.2019.00025","article-title":"Molecular mechanisms of TDP-43 misfolding and pathology in amyotrophic lateral sclerosis","volume":"12","author":"Prasad","year":"2019","journal-title":"Front. Mol. Neurosci."},{"key":"B372","doi-asserted-by":"publisher","first-page":"433","DOI":"10.3390\/biom12030433","article-title":"Multiple sclerosis and microbiome","volume":"12","author":"Preiningerova","year":"2022","journal-title":"Biomolecules"},{"key":"B373","doi-asserted-by":"publisher","first-page":"707","DOI":"10.3390\/life12050707","article-title":"Does glyphosate affect the human microbiota?","volume":"12","author":"Puigb\u00f2","year":"2022","journal-title":"Life"},{"key":"B374","doi-asserted-by":"publisher","first-page":"137306","DOI":"10.1016\/j.jhazmat.2025.137306","article-title":"Polylactic acid microplastics before and after aging induced neurotoxicity in zebrafish by disrupting the microbiota-gut-brain axis","volume":"488","author":"Qian","year":"2025","journal-title":"J. Hazard. Mater."},{"key":"B375","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.bbi.2018.02.016","article-title":"Alteration of the fecal microbiota in Chinese patients with Parkinson's disease","volume":"70","author":"Qian","year":"2018","journal-title":"Brain Behav. Immun."},{"key":"B376","doi-asserted-by":"publisher","first-page":"e00849","DOI":"10.1128\/spectrum.00849-23","article-title":"Improvement in zebrafish with diabetes and Alzheimer's disease treated with pasteurized akkermansia muciniphila","volume":"11","author":"Qu","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"B377","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1007\/s00394-024-03546-0","article-title":"The effects of 3-month supplementation with synbiotic on patient-reported outcomes, exercise tolerance, and brain and muscle metabolism in adult patients with post-COVID-19 chronic fatigue syndrome (STOP-FATIGUE): a randomized Placebo-controlled clinical trial","volume":"64","author":"Ranisavljev","year":"2024","journal-title":"Eur. J. Nutr."},{"key":"B378","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1192\/bja.2020.82","article-title":"The immunology of stress and the impact of inflammation on the brain and behaviour","volume":"27","author":"Ravi","year":"2021","journal-title":"BJPsych Adv."},{"key":"B379","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.neuron.2011.09.010","article-title":"A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD","volume":"72","author":"Renton","year":"2011","journal-title":"Neuron"},{"key":"B380","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1038\/nrgastro.2009.35","article-title":"Principles and clinical implications of the brain-gut-enteric microbiota axis","volume":"6","author":"Rhee","year":"2009","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"B381","doi-asserted-by":"publisher","first-page":"1666","DOI":"10.4103\/1673-5374.332127","article-title":"Amyloid-beta peptide and tau protein crosstalk in Alzheimer's disease","volume":"17","author":"Roda","year":"2022","journal-title":"Neural. Regen. Res."},{"key":"B382","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1038\/mp.2016.50","article-title":"From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways","volume":"21","author":"Rogers","year":"2016","journal-title":"Mol. Psychiatry"},{"key":"B383","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1126\/scitranslmed.3004291","article-title":"Disruption of the sleep-wake cycle and diurnal fluctuation of \u03b2-amyloid in mice with Alzheimer's disease pathology","volume":"4","author":"Roh","year":"2012","journal-title":"Sci. Transl. Med."},{"key":"B384","doi-asserted-by":"publisher","first-page":"4353","DOI":"10.3390\/ijms26094353","article-title":"Galactooligosaccharides attenuate behavioural, haematological and immunological abnormalities and influence gut microbiota in rats with amygdala hyperactivation induced by electrical stimulation","volume":"26","author":"Ruci\u0144ski","year":"2025","journal-title":"IJMS"},{"key":"B385","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1038\/s41575-021-00440-6","article-title":"The international scientific association of probiotics and prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics","volume":"18","author":"Salminen","year":"2021","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"B386","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.chom.2023.01.011","article-title":"Revealing gut microbiome associations with CFS","volume":"31","author":"Sampson","year":"2023","journal-title":"Cell Host Microbe"},{"key":"B387","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1016\/j.cell.2016.11.018","article-title":"Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson's disease","volume":"167","author":"Sampson","year":"2016","journal-title":"Cell"},{"key":"B388","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jad.2020.01.102","article-title":"Gut microbiota and major depressive disorder: a systematic review and meta-analysis","volume":"266","author":"Sanada","year":"2020","journal-title":"J. Affect. Disord."},{"key":"B389","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1038\/s41598-017-18877-8","article-title":"Low amounts of dietary fibre increase in vitro production of short-chain fatty acids without changing human colonic microbiota structure","volume":"8","author":"Sasaki","year":"2018","journal-title":"Sci. Rep."},{"key":"B390","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.1111\/nmo.12427","article-title":"Bifidobacteria exert strain-specific effects on stress-related behavior and physiology in BALB\/c mice","volume":"26","author":"Savignac","year":"2014","journal-title":"Neurogastroenterol. Motil."},{"key":"B391","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1002\/mds.26069","article-title":"Gut microbiota are related to Parkinson's disease and clinical phenotype","volume":"30","author":"Scheperjans","year":"2015","journal-title":"Mov. Disord."},{"key":"B392","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1016\/j.schres.2017.04.017","article-title":"Analysis of microbiota in first episode psychosis identifies preliminary associations with symptom severity and treatment response","volume":"192","author":"Schwarz","year":"2018","journal-title":"Schizophr. Res."},{"key":"B393","doi-asserted-by":"publisher","first-page":"15316","DOI":"10.3390\/ijms242015316","article-title":"Investigating antibody reactivity to the intestinal microbiome in severe myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS): a feasibility study","volume":"24","author":"Seton","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"B394","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1007\/s12031-021-01812-y","article-title":"An 8-week administration of Bifidobacterium bifidum and Lactobacillus plantarum combined with exercise training alleviates neurotoxicity of A\u03b2 and spatial learning via acetylcholine in Alzheimer rat model","volume":"71","author":"Shamsipour","year":"2021","journal-title":"J. Mol. Neurosci."},{"key":"B395","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1007\/s00284-012-0277-2","article-title":"The effect of glyphosate on potential pathogens and beneficial members of poultry microbiota in vitro","volume":"66","author":"Shehata","year":"2013","journal-title":"Curr. Microbiol."},{"key":"B396","doi-asserted-by":"publisher","first-page":"385","DOI":"10.3233\/JAD-160884","article-title":"Alzheimer's disease histological and behavioral manifestations in transgenic mice correlate with specific gut microbiome state","volume":"56","author":"Shen","year":"2017","journal-title":"J. Alzheimer. Dis."},{"key":"B397","doi-asserted-by":"publisher","first-page":"263","DOI":"10.31887\/DCNS.2011.13.2\/jsherin","article-title":"Post-traumatic stress disorder: the neurobiological impact of psychological trauma","volume":"13","author":"Sherin","year":"2011","journal-title":"Dial. Clin. Neurosci."},{"key":"B398","doi-asserted-by":"publisher","first-page":"8534","DOI":"10.1038\/s41598-022-12578-7","article-title":"Alterations of the gut microbial community structure and function with aging in the spontaneously hypertensive stroke prone rat","volume":"12","author":"Shi","year":"2022","journal-title":"Sci. Rep."},{"key":"B399","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.tibtech.2015.06.011","article-title":"Proteobacteria: microbial signature of dysbiosis in gut microbiota","volume":"33","author":"Shin","year":"2015","journal-title":"Trends Biotechnol."},{"key":"B400","doi-asserted-by":"publisher","first-page":"25","DOI":"10.3389\/fendo.2020.00025","article-title":"The role of short-chain fatty acids from gut microbiota in gut-brain communication","volume":"11","author":"Silva","year":"2020","journal-title":"Front. Endocrinol."},{"key":"B401","doi-asserted-by":"publisher","first-page":"7428","DOI":"10.1523\/JNEUROSCI.1114-16.2016","article-title":"Microbiota dysbiosis controls the neuroinflammatory response after stroke","volume":"36","author":"Singh","year":"2016","journal-title":"J. Neurosci."},{"key":"B402","doi-asserted-by":"publisher","first-page":"e073275","DOI":"10.1136\/bmjopen-2023-073275","article-title":"Faecal microbiota transplantation (FMT) in Norwegian outpatients with mild to severe myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS): protocol for a 12-month randomised double-blind placebo-controlled trial","volume":"14","author":"Skjevling","year":"2024","journal-title":"BMJ Open"},{"key":"B403","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.ebiom.2017.09.013","article-title":"Effect of Lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: a randomised double-blind placebo-controlled trial","volume":"24","author":"Slykerman","year":"2017","journal-title":"EBioMedicine"},{"key":"B404","doi-asserted-by":"publisher","first-page":"105840","DOI":"10.1016\/j.phrs.2021.105840","article-title":"The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders","volume":"172","author":"Soca\u0142a","year":"2021","journal-title":"Pharmacol. Res."},{"key":"B405","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1111\/acn.12016","article-title":"Activation of GABAA receptors in the medial prefrontal cortex produces an anxiolytic-like response","volume":"25","author":"Solati","year":"2013","journal-title":"Acta Neuropsychiatr."},{"key":"B406","doi-asserted-by":"publisher","first-page":"e0033820","DOI":"10.1128\/CMR.00338-20","article-title":"A comprehensive review on the role of the gut microbiome in human neurological disorders","volume":"35","author":"Sorboni","year":"2022","journal-title":"Clin. Microbiol. Rev."},{"key":"B407","doi-asserted-by":"publisher","first-page":"16870","DOI":"10.3390\/ijms242316870","article-title":"Major depressive disorder and gut microbiota: role of physical exercise","volume":"24","author":"Souza","year":"2023","journal-title":"IJMS"},{"key":"B408","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1001\/jamaneurol.2013.4258","article-title":"Self-reported sleep and \u03b2-amyloid deposition in community-dwelling older adults","volume":"70","author":"Spira","year":"2013","journal-title":"JAMA Neurol"},{"key":"B409","doi-asserted-by":"publisher","first-page":"1352744","DOI":"10.3389\/fimmu.2024.1352744","article-title":"The gastrointestinal microbiota in the development of ME\/CFS: a critical view and potential perspectives","volume":"15","author":"Stallmach","year":"2024","journal-title":"Front. Immunol."},{"key":"B410","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1038\/nm.4194","article-title":"Translocation and dissemination of commensal bacteria in post-stroke infection","volume":"22","author":"Stanley","year":"2016","journal-title":"Nat. Med."},{"key":"B411","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1001\/jamapsychiatry.2016.0350","article-title":"Genome-wide association studies of posttraumatic stress disorder in 2 cohorts of US army soldiers","volume":"73","author":"Stein","year":"2016","journal-title":"JAMA Psychiatry"},{"key":"B412","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.neuint.2016.06.011","article-title":"The neuropharmacology of butyrate: the bread and butter of the microbiota-gut-brain axis?","volume":"99","author":"Stilling","year":"2016","journal-title":"Neurochem. Int."},{"key":"B413","doi-asserted-by":"publisher","first-page":"289","DOI":"10.3390\/biomedicines10020289","article-title":"Implication of intestinal barrier dysfunction in gut dysbiosis and diseases","volume":"10","author":"Stolfi","year":"2022","journal-title":"Biomedicines"},{"key":"B414","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1038\/s41564-018-0307-3","article-title":"GABA-modulating bacteria of the human gut microbiota","volume":"4","author":"Strandwitz","year":"2018","journal-title":"Nat. Microbiol."},{"key":"B415","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1113\/jphysiol.2004.063388","article-title":"Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice","volume":"558","author":"Sudo","year":"2004","journal-title":"J. Physiol."},{"key":"B416","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1016\/j.bbi.2020.10.014","article-title":"Probiotic Clostridium butyricum ameliorated motor deficits in a mouse model of Parkinson's disease via gut microbiota-GLP-1 pathway","volume":"91","author":"Sun","year":"2021","journal-title":"Brain Behav. Immun."},{"key":"B417","doi-asserted-by":"publisher","first-page":"3006","DOI":"10.1021\/acs.jafc.8b07313","article-title":"Fructooligosaccharides ameliorating cognitive deficits and neurodegeneration in APP\/PS1 transgenic mice through modulating gut microbiota","volume":"67","author":"Sun","year":"","journal-title":"J. Agric. Food Chem."},{"key":"B418","doi-asserted-by":"publisher","first-page":"154030","DOI":"10.1016\/j.tox.2024.154030","article-title":"Microplastics\/nanoplastics and neurological health: an overview of neurological defects and mechanisms","volume":"511","author":"Sun","year":"2025","journal-title":"Toxicology"},{"key":"B419","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1038\/s41398-019-0525-3","article-title":"Fecal microbiota transplantation alleviated Alzheimer's disease-like pathogenesis in APP\/PS1 transgenic mice","volume":"9","author":"Sun","year":"","journal-title":"Transl. Psychiatry"},{"key":"B420","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/toxsci\/kfaa060","article-title":"The gut microbiome and xenobiotics: identifying knowledge gaps","volume":"176","author":"Sutherland","year":"2020","journal-title":"Toxicol. Sci."},{"key":"B421","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1002\/ana.24448","article-title":"Vagotomy and subsequent risk of P arkinson's disease","volume":"78","author":"Svensson","year":"2015","journal-title":"Ann. Neurol."},{"key":"B422","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1016\/j.clnu.2018.05.018","article-title":"Clinical and metabolic response to probiotic administration in people with Parkinson's disease: a randomized, double-blind, placebo-controlled trial","volume":"38","author":"Tamtaji","year":"2019","journal-title":"Clin. Nutr."},{"key":"B423","doi-asserted-by":"publisher","first-page":"e772","DOI":"10.1212\/WNL.0000000000010998","article-title":"Probiotics for constipation in Parkinson disease: a randomized placebo-controlled study","volume":"96","author":"Tan","year":"2021","journal-title":"Neurology"},{"key":"B424","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/s40168-017-0293-3","article-title":"Potential and active functions in the gut microbiota of a healthy human cohort","volume":"5","author":"Tanca","year":"2017","journal-title":"Microbiome"},{"key":"B425","doi-asserted-by":"publisher","first-page":"100533","DOI":"10.1016\/j.ynstr.2023.100533","article-title":"Differences in gut microbiota associated with stress resilience and susceptibility to single prolonged stress in female rodents","volume":"24","author":"Tanelian","year":"2023","journal-title":"Neurobiol. Stress"},{"key":"B426","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1177\/1352458517737390","article-title":"Investigation of probiotics in multiple sclerosis","volume":"24","author":"Tankou","year":"","journal-title":"Mult. Scler."},{"key":"B427","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1002\/ana.25244","article-title":"A probiotic modulates the microbiome and immunity in multiple sclerosis","volume":"83","author":"Tankou","year":"","journal-title":"Ann. Neurol."},{"key":"B428","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1038\/nature20413","article-title":"Decoding ALS: from genes to mechanism","volume":"539","author":"Taylor","year":"2016","journal-title":"Nature"},{"key":"B429","doi-asserted-by":"publisher","first-page":"e15417","DOI":"10.1016\/j.heliyon.2023.e15417","article-title":"The influence of antibiotic treatment on the behavior and gut microbiome of adult rats neonatally insulted with lipopolysaccharide","volume":"9","author":"Tejkalov\u00e1","year":"2023","journal-title":"Heliyon"},{"key":"B430","doi-asserted-by":"publisher","first-page":"114621","DOI":"10.1016\/j.physbeh.2024.114621","article-title":"Antibiotic-induced gut microbe dysbiosis alters neurobehavior in mice through modulation of BDNF and gut integrity","volume":"283","author":"Thabet","year":"2024","journal-title":"Physiol. Behav."},{"key":"B431","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10753-022-01721-1","article-title":"Neuroinflammation in Alzheimer's disease: current progress in molecular signaling and therapeutics","volume":"46","author":"Thakur","year":"2023","journal-title":"Inflammation"},{"key":"B432","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1007\/s00401-011-0871-6","article-title":"Stages of granulovacuolar degeneration: their relation to Alzheimer's disease and chronic stress response","volume":"122","author":"Thal","year":"2011","journal-title":"Acta Neuropathol."},{"key":"B433","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/S1474-4422(17)30470-2","article-title":"Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria","volume":"17","author":"Thompson","year":"2018","journal-title":"Lancet Neurol."},{"key":"B434","doi-asserted-by":"publisher","first-page":"3848","DOI":"10.1038\/s41598-020-60679-y","article-title":"Dietary prebiotics alter novel microbial dependent fecal metabolites that improve sleep","volume":"10","author":"Thompson","year":"2020","journal-title":"Sci. Rep."},{"key":"B435","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.jnutbio.2019.01.007","article-title":"Bifidobacterium with the role of 5-hydroxytryptophan synthesis regulation alleviates the symptom of depression and related microbiota dysbiosis","volume":"66","author":"Tian","year":"","journal-title":"J. Nutr. Biochem."},{"key":"B436","doi-asserted-by":"publisher","first-page":"7588","DOI":"10.1039\/C9FO01630A","article-title":"Ingestion of Bifidobacterium longum subspecies infantis strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiota","volume":"10","author":"Tian","year":"","journal-title":"Food Funct."},{"key":"B437","doi-asserted-by":"publisher","first-page":"404","DOI":"10.3389\/fphar.2019.00404","article-title":"Therapeutic challenges of post-traumatic stress disorder: focus on the dopaminergic system","volume":"10","author":"Torrisi","year":"2019","journal-title":"Front. Pharmacol."},{"key":"B438","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1111\/apt.12878","article-title":"Systematic review: the role of the gut microbiota in chemotherapy- or radiation-induced gastrointestinal mucositis \u2013 current evidence and potential clinical applications","volume":"40","author":"Touchefeu","year":"2014","journal-title":"Alimentary Pharmacol. Therap."},{"key":"B439","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.jns.2016.02.042","article-title":"Gut microbiota composition and relapse risk in pediatric MS: a pilot study","volume":"363","author":"Tremlett","year":"2016","journal-title":"J. Neurol. Sci."},{"key":"B440","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1111\/ejn.14720","article-title":"Neuroinflammation and depression: a review","volume":"53","author":"Troubat","year":"2021","journal-title":"Eur. J. Neurosci."},{"key":"B441","doi-asserted-by":"publisher","first-page":"4716","DOI":"10.3390\/ijms20194716","article-title":"Metabolic and vascular effect of the mediterranean diet","volume":"20","author":"Tuttolomondo","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"B442","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1038\/s41538-025-00369-z","article-title":"Limosilactobacillus reuteri fermented brown rice alleviates anxiety improves cognition and modulates gut microbiota in stressed mice","volume":"9","author":"Tyagi","year":"2025","journal-title":"NPJ Sci. Food"},{"key":"B443","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s13024-018-0257-5","article-title":"Inoculation of \u03b1-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve","volume":"13","author":"Uemura","year":"2018","journal-title":"Mol. Neurodegener."},{"key":"B444","doi-asserted-by":"publisher","first-page":"2067","DOI":"10.3389\/fimmu.2019.02067","article-title":"Interactome of the autoimmune risk protein ANKRD55","volume":"10","author":"Ugidos","year":"2019","journal-title":"Front. Immunol."},{"key":"B445","doi-asserted-by":"publisher","first-page":"100627","DOI":"10.1016\/j.bbih.2023.100627","article-title":"Suppressed immune and metabolic responses to intestinal damage-associated microbial translocation in myalgic encephalomyelitis\/chronic fatigue syndrome","volume":"30","author":"Uhde","year":"2023","journal-title":"Brain Behav. Immun. Health"},{"key":"B446","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.parkreldis.2016.08.019","article-title":"Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls","volume":"32","author":"Unger","year":"2016","journal-title":"Parkinson. Relat. Disord."},{"key":"B447","doi-asserted-by":"publisher","first-page":"2655","DOI":"10.3389\/fimmu.2019.02655","article-title":"Interactions between gut microbiota and acute restraint stress in peripheral structures of the hypothalamic\u2013pituitary\u2013adrenal axis and the intestine of male mice","volume":"10","author":"Vagnerov\u00e1","year":"2019","journal-title":"Front. Immunol."},{"key":"B448","doi-asserted-by":"publisher","first-page":"2548","DOI":"10.3390\/microorganisms9122548","article-title":"Impact of the age of cecal material transfer donors on Alzheimer's disease pathology in 5xFAD mice","volume":"9","author":"Valeri","year":"2021","journal-title":"Microorganisms"},{"key":"B449","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1111\/lam.13543","article-title":"The efficacy of probiotics in experimental autoimmune encephalomyelitis (an animal model for MS): a systematic review and meta-analysis","volume":"73","author":"Valizadeh","year":"2021","journal-title":"Lett. Appl. Microbiol."},{"key":"B450","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1038\/s41564-018-0337-x","article-title":"The neuroactive potential of the human gut microbiota in quality of life and depression","volume":"4","author":"Valles-Colomer","year":"2019","journal-title":"Nat. Microbiol."},{"key":"B451","doi-asserted-by":"publisher","first-page":"2818","DOI":"10.3390\/ijms20112818","article-title":"Pathophysiology and diagnosis of ALS: insights from advances in neurophysiological techniques","volume":"20","author":"van den Bos","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"B452","doi-asserted-by":"publisher","first-page":"5077","DOI":"10.3390\/jcm10215077","article-title":"The emerging role of gut microbiota in myalgic encephalomyelitis\/chronic fatigue syndrome (ME\/CFS): current evidence and potential therapeutic applications","volume":"10","author":"Varesi","year":"2021","journal-title":"J. Clin. Med"},{"key":"B453","doi-asserted-by":"publisher","first-page":"98","DOI":"10.3389\/fcimb.2020.00098","article-title":"Fecal microbiota transplantation in neurological disorders","volume":"10","author":"Vendrik","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"B454","doi-asserted-by":"publisher","first-page":"110775","DOI":"10.1016\/j.cbi.2023.110775","article-title":"Pelvic irradiation induces behavioural and neuronal damage through gut dysbiosis in a rat model","volume":"386","author":"Venkidesh","year":"2023","journal-title":"Chem. Biol. Interact."},{"key":"B455","doi-asserted-by":"publisher","first-page":"14876","DOI":"10.1038\/s41598-017-13974-0","article-title":"Bile acid TUDCA improves insulin clearance by increasing the expression of insulin-degrading enzyme in the liver of obese mice","volume":"7","author":"Vettorazzi","year":"2017","journal-title":"Sci. Rep."},{"key":"B456","doi-asserted-by":"publisher","first-page":"eabq2422","DOI":"10.1126\/sciadv.abq2422","article-title":"Systemic antibody responses against human microbiota flagellins are overrepresented in chronic fatigue syndrome patients","volume":"8","author":"Vogl","year":"2022","journal-title":"Sci. Adv."},{"key":"B457","doi-asserted-by":"publisher","first-page":"13537","DOI":"10.1038\/s41598-017-13601-y","article-title":"Gut microbiome alterations in Alzheimer's disease","volume":"7","author":"Vogt","year":"2017","journal-title":"Sci. Rep."},{"key":"B458","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1186\/s13195-018-0451-2","article-title":"The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease","volume":"10","author":"Vogt","year":"2018","journal-title":"Alzheimers. Res. Ther."},{"key":"B459","doi-asserted-by":"publisher","first-page":"1477519","DOI":"10.3389\/fnins.2024.1477519","article-title":"Prebiotics as an adjunct therapy for posttraumatic stress disorder: a pilot randomized controlled trial","volume":"18","author":"Voigt","year":"2025","journal-title":"Front. Neurosci."},{"key":"B460","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1159\/000526947","article-title":"Association between gut microbiota with mild cognitive impairment and Alzheimer's disease in a Thai population","volume":"22","author":"Wanapaisan","year":"2022","journal-title":"Neurodegener. Dis."},{"key":"B461","doi-asserted-by":"publisher","first-page":"e0126312","DOI":"10.1371\/journal.pone.0126312","article-title":"Gut microbial dysbiosis may predict diarrhea and fatigue in patients undergoing pelvic cancer radiotherapy: a pilot study","volume":"10","author":"Wang","year":"2015","journal-title":"PLoS ONE"},{"key":"B462","doi-asserted-by":"publisher","first-page":"1158057","DOI":"10.3389\/fnins.2023.1158057","article-title":"Interventional strategies for ischemic stroke based on the modulation of the gut microbiota","volume":"17","author":"Wang","year":"","journal-title":"Front. Neurosci."},{"key":"B463","doi-asserted-by":"publisher","first-page":"166057","DOI":"10.1016\/j.scitotenv.2023.166057","article-title":"The enhancement in toxic potency of oxidized functionalized polyethylene-microplastics in mice gut and Caco-2 cells","volume":"903","author":"Wang","year":"","journal-title":"Sci. Total Environ."},{"key":"B464","doi-asserted-by":"publisher","first-page":"108523","DOI":"10.1016\/j.envint.2024.108523","article-title":"Oxidized\/unmodified-polyethylene microplastics neurotoxicity in mice: Perspective from microbiota-gut-brain axis","volume":"185","author":"Wang","year":"2024","journal-title":"Environ. Int."},{"key":"B465","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1186\/s40001-024-01747-1","article-title":"Clinical evidence of the link between gut microbiome and myalgic encephalomyelitis\/chronic fatigue syndrome: a retrospective review","volume":"29","author":"Wang","year":"2024","journal-title":"Eur. J. Med. Res."},{"key":"B466","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1186\/s13014-021-01899-y","article-title":"The impact of pelvic radiotherapy on the gut microbiome and its role in radiation-induced diarrhoea: a systematic review","volume":"16","author":"Wang","year":"2021","journal-title":"Radiat. Oncol."},{"key":"B467","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.bbi.2021.06.003","article-title":"Exploring the microbiota-Alzheimer's disease linkage using short-term antibiotic treatment followed by fecal microbiota transplantation","volume":"96","author":"Wang","year":"","journal-title":"Brain Behav. Immun"},{"key":"B468","doi-asserted-by":"publisher","first-page":"3083","DOI":"10.2147\/JIR.S350109","article-title":"Microglia-mediated neuroinflammation: a potential target for the treatment of cardiovascular diseases","volume":"15","author":"Wang","year":"2022","journal-title":"J. Inflamm. Res."},{"key":"B469","doi-asserted-by":"publisher","first-page":"2571","DOI":"10.1093\/brain\/awab156","article-title":"The role of gut dysbiosis in Parkinson's disease: mechanistic insights and therapeutic options","volume":"144","author":"Wang","year":"2021","journal-title":"Brain"},{"key":"B470","doi-asserted-by":"publisher","first-page":"17562848251347347","DOI":"10.1177\/17562848251347347","article-title":"Radiation-induced injury and the gut microbiota: insights from a microbial perspective","volume":"18","author":"Wang","year":"2025","journal-title":"Therap. Adv. Gastroenterol."},{"key":"B471","doi-asserted-by":"publisher","first-page":"628","DOI":"10.18632\/aging.102645","article-title":"Concomitant memantine and Lactobacillus plantarum treatment attenuates cognitive impairments in APP\/PS1 mice","volume":"12","author":"Wang","year":"2020","journal-title":"Aging"},{"key":"B472","doi-asserted-by":"publisher","first-page":"15682","DOI":"10.18632\/aging.103776","article-title":"Vascular, inflammatory and metabolic risk factors in relation to dementia in Parkinson's disease patients with type 2 diabetes mellitus","volume":"12","author":"Wang","year":"2020","journal-title":"Aging"},{"key":"B473","doi-asserted-by":"publisher","first-page":"2200265","DOI":"10.1002\/mnfr.202200265","article-title":"Modulation of the gut microbiota and glycometabolism by a probiotic to alleviate amyloid accumulation and cognitive impairments in AD rats","volume":"66","author":"Wang","year":"2022","journal-title":"Mol. Nutr. Food Res."},{"key":"B474","doi-asserted-by":"publisher","first-page":"2750","DOI":"10.3389\/fimmu.2019.02750","article-title":"Induction of intestinal Th17 cells by flagellins from segmented filamentous bacteria","volume":"10","author":"Wang","year":"2019","journal-title":"Front. Immunol."},{"key":"B475","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/s13024-025-00857-6","article-title":"Alzheimer's disease pathogenesis: standing at the crossroad of lipid metabolism and immune response","volume":"20","author":"Wang","year":"2025","journal-title":"Mol. Neurodegener."},{"key":"B476","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1038\/s41531-019-0100-x","article-title":"Effect of Parkinson's disease and related medications on the composition of the fecal bacterial microbiota","volume":"5","author":"Weis","year":"2019","journal-title":"NPJ Parkinsons Dis."},{"key":"B477","doi-asserted-by":"publisher","first-page":"5697","DOI":"10.1038\/s41467-024-49972-w","article-title":"Humid heat environment causes anxiety-like disorder via impairing gut microbiota and bile acid metabolism in mice","volume":"15","author":"Weng","year":"2024","journal-title":"Nat. Commun."},{"key":"B478","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1016\/j.molimm.2005.06.039","article-title":"Molecular mimicry or structural mimicry?","volume":"43","author":"Westall","year":"2006","journal-title":"Mol. Immunol."},{"key":"B479","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.chom.2017.06.007","article-title":"Indoleacrylic acid produced by commensal Peptostreptococcus species suppresses inflammation","volume":"22","author":"Wlodarska","year":"2017","journal-title":"Cell Host Microbe"},{"key":"B480","doi-asserted-by":"publisher","first-page":"100264","DOI":"10.1016\/j.bbih.2021.100264","article-title":"Inflammation plays a causal role in fatigue-like behavior induced by pelvic irradiation in mice","volume":"15","author":"Wolff","year":"2021","journal-title":"Brain Behav. Immun. Health"},{"key":"B481","doi-asserted-by":"publisher","first-page":"2878","DOI":"10.3390\/nu13082878","article-title":"Potential benefits of probiotics and prebiotics for coronary heart disease and stroke","volume":"13","author":"Wu","year":"2021","journal-title":"Nutrients"},{"key":"B482","doi-asserted-by":"publisher","first-page":"1767421","DOI":"10.1155\/2022\/1767421","article-title":"Mechanism of Salvia miltiorrhiza Bge. for the treatment of ischemic stroke based on bioinformatics and network pharmacology","volume":"2022","author":"Wu","year":"2022","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"B483","doi-asserted-by":"publisher","first-page":"117228","DOI":"10.1016\/j.biopha.2024.117228","article-title":"Molecular mechanism and therapeutic strategy of bile acids in Alzheimer's disease from the emerging perspective of the microbiota\u2013gut\u2013brain axis","volume":"178","author":"Wu","year":"2024","journal-title":"Biomed. Pharmacother."},{"key":"B484","doi-asserted-by":"publisher","first-page":"129361","DOI":"10.1016\/j.jhazmat.2022.129361","article-title":"Absorption, distribution, metabolism, excretion and toxicity of microplastics in the human body and health implications","volume":"437","author":"Wu","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"B485","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.jad.2024.12.086","article-title":"Trends in the epidemiology of anxiety disorders from 1990 to 2021: a global, regional, and national analysis with a focus on the sociodemographic index","volume":"373","author":"Wu","year":"2025","journal-title":"J. Affect. Disord."},{"key":"B486","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1186\/s40168-020-00845-6","article-title":"Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein","volume":"8","author":"Xiao","year":"2020","journal-title":"Microbiome"},{"key":"B487","doi-asserted-by":"publisher","first-page":"519","DOI":"10.4103\/1673-5374.380869","article-title":"Immune regulation of the gut-brain axis and lung-brain axis involved in ischemic stroke","volume":"19","author":"Xie","year":"2024","journal-title":"Neural. Regen. Res."},{"key":"B488","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.chom.2023.01.001","article-title":"Multi-'omics of gut microbiome-host interactions in short- and long-term myalgic encephalomyelitis\/chronic fatigue syndrome patients","volume":"31","author":"Xiong","year":"2023","journal-title":"Cell Host Microbe"},{"key":"B489","doi-asserted-by":"publisher","first-page":"3258","DOI":"10.3390\/nu15143258","article-title":"The role of gut microbiota in anxiety, depression, and other mental disorders as well as the protective effects of dietary components","volume":"15","author":"Xiong","year":"2023","journal-title":"Nutrients"},{"key":"B490","doi-asserted-by":"publisher","first-page":"e0120270","DOI":"10.1371\/journal.pone.0120270","article-title":"A Meta-analysis of risk factors for combat-related PTSD among military personnel and veterans","volume":"10","author":"Xue","year":"2015","journal-title":"PLoS ONE"},{"key":"B491","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1016\/j.bpsgos.2023.03.005","article-title":"Repeated social defeat stress induces an inflammatory gut milieu by altering the mucosal barrier integrity and gut microbiota homeostasis","volume":"3","author":"Yadav","year":"2023","journal-title":"Biol. Psychiatry Glob. Open Sci."},{"key":"B492","doi-asserted-by":"publisher","first-page":"2353396","DOI":"10.1080\/19490976.2024.2353396","article-title":"Fecal microbiota transplantation significantly improved respiratory failure of amyotrophic lateral sclerosis","volume":"16","author":"Yan","year":"2024","journal-title":"Gut Microbes"},{"key":"B493","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1038\/s41398-017-0031-4","article-title":"Possible role of the gut microbiota\u2013brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model","volume":"7","author":"Yang","year":"2017","journal-title":"Transl. Psychiatry"},{"key":"B494","doi-asserted-by":"publisher","first-page":"164619","DOI":"10.1016\/j.scitotenv.2023.164619","article-title":"Epigallocatechin-3-gallate ameliorates polystyrene microplastics-induced anxiety-like behavior in mice by modulating gut microbe homeostasis","volume":"892","author":"Yang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"B495","doi-asserted-by":"publisher","first-page":"1116558","DOI":"10.3389\/fphar.2023.1116558","article-title":"Pathogenesis and therapy of radiation enteritis with gut microbiota","volume":"14","author":"Yang","year":"2023","journal-title":"Front. Pharmacol."},{"key":"B496","doi-asserted-by":"publisher","first-page":"3047","DOI":"10.1017\/S0033291721005092","article-title":"Evaluating the interactive effects of dietary habits and human gut microbiome on the risks of depression and anxiety","volume":"53","author":"Yao","year":"2023","journal-title":"Psychol. Med."},{"key":"B497","doi-asserted-by":"publisher","first-page":"1504065","DOI":"10.3389\/fnana.2025.1504065","article-title":"Exploring the microbiota-gut-brain axis: impact on brain structure and function","volume":"19","author":"Yassin","year":"2025","journal-title":"Front. Neuroanat."},{"key":"B498","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1186\/s40164-023-00410-5","article-title":"The gut microbiota as a booster for radiotherapy: novel insights into radio-protection and radiation injury","volume":"12","author":"Yi","year":"2023","journal-title":"Exp. Hematol. Oncol."},{"key":"B499","doi-asserted-by":"publisher","first-page":"e002699","DOI":"10.1161\/JAHA.115.002699","article-title":"Dysbiosis of gut microbiota with reduced trimethylamine-N-oxide level in patients with large-artery atherosclerotic stroke or transient ischemic attack","volume":"4","author":"Yin","year":"2015","journal-title":"J. Am. Heart Assoc."},{"key":"B500","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1037\/tra0001727","article-title":"Microbiome signature of posttraumatic stress disorder and resilience in youth","volume":"16","author":"Yirmiya","year":"2024","journal-title":"Psychol. Trauma Theory Res. Pract. Policy"},{"key":"B501","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/s13041-017-0306-y","article-title":"The role of 5-HT receptors in depression","volume":"10","author":"Yohn","year":"2017","journal-title":"Mol. Brain"},{"key":"B502","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1111\/bdi.12416","article-title":"Individuals hospitalized with acute mania have increased exposure to antimicrobial medications","volume":"18","author":"Yolken","year":"2016","journal-title":"Bipolar Disord."},{"key":"B503","doi-asserted-by":"publisher","first-page":"5127157","DOI":"10.1155\/2023\/5127157","article-title":"The role of gut microbiota in various neurological and psychiatric disorders-an evidence mapping based on quantified evidence","volume":"2023","author":"Zang","year":"2023","journal-title":"Mediators Inflamm."},{"key":"B504","doi-asserted-by":"publisher","first-page":"22273","DOI":"10.1038\/s41598-022-26915-3","article-title":"The bile acid TUDCA reduces age-related hyperinsulinemia in mice","volume":"12","author":"Zangerolamo","year":"2022","journal-title":"Sci. Rep."},{"key":"B505","doi-asserted-by":"publisher","first-page":"2324","DOI":"10.1212\/WNL.0000000000003391","article-title":"Gram-negative bacterial molecules associate with Alzheimer disease pathology","volume":"87","author":"Zhan","year":"2016","journal-title":"Neurology"},{"key":"B506","doi-asserted-by":"publisher","first-page":"3237","DOI":"10.1007\/s10653-021-00840-2","article-title":"Exposure to antibiotics and mental disorders in children: a community-based cross-sectional study","volume":"43","author":"Zhang","year":"","journal-title":"Environ. Geochem. Health"},{"key":"B507","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1021\/acs.estlett.1c00559","article-title":"Occurrence of polyethylene terephthalate and polycarbonate microplastics in infant and adult feces","volume":"8","author":"Zhang","year":"","journal-title":"Environ. Sci. Technol. Lett."},{"key":"B508","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.3233\/JAD-170020","article-title":"Altered gut microbiota in a mouse model of Alzheimer's disease","volume":"60","author":"Zhang","year":"2017","journal-title":"JAD"},{"key":"B509","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1007\/s12975-022-01096-3","article-title":"Gut microbiota in ischemic stroke: role of gut bacteria-derived metabolites","volume":"14","author":"Zhang","year":"2023","journal-title":"Transl. Stroke Res."},{"key":"B510","doi-asserted-by":"publisher","first-page":"10306","DOI":"10.1111\/jcmm.16951","article-title":"Gut metabolite Urolithin A mitigates ionizing radiation-induced intestinal damage","volume":"25","author":"Zhang","year":"","journal-title":"J. Cell. Mol. Med."},{"key":"B511","doi-asserted-by":"publisher","first-page":"10041","DOI":"10.1039\/D3FO0C","article-title":"The effects of Lactobacillus reuteri microcapsules on radiation-induced brain injury by regulating the gut microenvironment","volume":"14","author":"Zhang","year":"2023","journal-title":"Food Funct."},{"key":"B512","doi-asserted-by":"publisher","first-page":"113585","DOI":"10.1016\/j.expneurol.2020.113585","article-title":"Gut microbiota-brain interaction: an emerging immunotherapy for traumatic brain injury","volume":"337","author":"Zhang","year":"","journal-title":"Exp. Neurol."},{"key":"B513","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1126\/science.aao5774","article-title":"Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes","volume":"359","author":"Zhao","year":"2018","journal-title":"Science"},{"key":"B514","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.3389\/fimmu.2017.01064","article-title":"Microbiome-derived lipopolysaccharide enriched in the perinuclear region of Alzheimer's disease brain","volume":"8","author":"Zhao","year":"2017","journal-title":"Front. Immunol."},{"key":"B515","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1186\/s40168-021-01107-9","article-title":"Fecal microbiota transplantation protects rotenone-induced Parkinson's disease mice via suppressing inflammation mediated by the lipopolysaccharide-TLR4 signaling pathway through the microbiota-gut-brain axis","volume":"9","author":"Zhao","year":"2021","journal-title":"Microbiome"},{"key":"B516","doi-asserted-by":"publisher","first-page":"4631","DOI":"10.3390\/nu15214631","article-title":"Understanding the gut\u2013brain axis and its therapeutic implications for neurodegenerative disorders","volume":"15","author":"Zheng","year":"2023","journal-title":"Nutrients"},{"key":"B517","doi-asserted-by":"publisher","first-page":"153799","DOI":"10.1016\/j.tox.2024.153799","article-title":"The effects of micro- and nanoplastics on the central nervous system: a new threat to humanity?","volume":"504","author":"Zheng","year":"2024","journal-title":"Toxicology"},{"key":"B518","doi-asserted-by":"publisher","first-page":"541","DOI":"10.26599\/FSHW.2022.9250049","article-title":"Diet and physical activity influence the composition of gut microbiota, benefit on Alzheimer's disease","volume":"13","author":"Zhou","year":"2024","journal-title":"Food Sci. Human Wellness"},{"key":"B519","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.jtcms.2020.10.005","article-title":"Correlation of gut microbiota and neurotransmitters in a rat model of post-traumatic stress disorder","volume":"7","author":"Zhou","year":"2020","journal-title":"J. Traditional Chin. Med. Sci."},{"key":"B520","doi-asserted-by":"publisher","first-page":"1081347","DOI":"10.3389\/fnins.2023.1081347","article-title":"Gut-brain axis: mechanisms and potential therapeutic strategies for ischemic stroke through immune functions","volume":"17","author":"Zhou","year":"2023","journal-title":"Front. Neurosci."},{"key":"B521","doi-asserted-by":"publisher","first-page":"5211","DOI":"10.3748\/wjg.v22.i22.5211","article-title":"Visceral hypersensitive rats share common dysbiosis features with irritable bowel syndrome patients","volume":"22","author":"Zhou","year":"2016","journal-title":"WJG"},{"key":"B522","doi-asserted-by":"publisher","first-page":"4646","DOI":"10.1021\/acs.jafc.3c00652","article-title":"Bifidobacterium breve HNXY26M4 attenuates cognitive deficits and neuroinflammation by regulating the gut\u2013brain axis in APP\/PS1 mice","volume":"71","author":"Zhu","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"B523","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.3390\/nu13051602","article-title":"Administration of Bifidobacterium breve improves the brain function of A\u03b21-42-treated mice via the modulation of the gut microbiome","volume":"13","author":"Zhu","year":"2021","journal-title":"Nutrients"},{"key":"B524","doi-asserted-by":"publisher","first-page":"1158137","DOI":"10.3389\/fimmu.2023.1158137","article-title":"Psychobiotic Lactobacillus plantarum JYLP-326 relieves anxiety, depression, and insomnia symptoms in test anxious college via modulating the gut microbiota and its metabolism","volume":"14","author":"Zhu","year":"2023","journal-title":"Front. Immunol."},{"key":"B525","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.3233\/JAD-180176","article-title":"Gut microbiota is altered in patients with Alzheimer's disease","volume":"63","author":"Zhuang","year":"2018","journal-title":"JAD"},{"key":"B526","doi-asserted-by":"publisher","first-page":"675206","DOI":"10.3389\/fnbeh.2021.675206","article-title":"Glucocorticoid abnormalities in female rats exposed to a predator-based psychosocial stress model of PTSD","volume":"15","author":"Zoladz","year":"2021","journal-title":"Front. Behav. Neurosci."}],"container-title":["Frontiers in Aging Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnagi.2025.1667448\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T05:52:31Z","timestamp":1759297951000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnagi.2025.1667448\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,1]]},"references-count":526,"alternative-id":["10.3389\/fnagi.2025.1667448"],"URL":"https:\/\/doi.org\/10.3389\/fnagi.2025.1667448","relation":{},"ISSN":["1663-4365"],"issn-type":[{"value":"1663-4365","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,1]]},"article-number":"1667448"}}