{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:58:16Z","timestamp":1790366296019,"version":"4.1.0"},"reference-count":162,"publisher":"Frontiers Media SA","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Front. Neuroanat."],"DOI":"10.3389\/fnana.2014.00016","type":"journal-article","created":{"date-parts":[[2014,3,26]],"date-time":"2014-03-26T07:22:41Z","timestamp":1395818561000},"source":"Crossref","is-referenced-by-count":31,"title":["Retrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and disease"],"prefix":"10.3389","volume":"8","author":[{"given":"Javier H.","family":"Jara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bar\u00c4\u00b1\u00c5\u0178","family":"Gen\u00c3\u00a7","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodi L.","family":"Klessner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. Hande","family":"\u00c3\u2013zdinler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2014,3,26]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1038\/nn.2538","article-title":"Sublayer-specific microcircuits of corticospinal and corticostriatal neurons in motor cortex","volume":"13","author":"Anderson","year":"2010","journal-title":"Nat. Neurosci"},{"key":"B2","doi-asserted-by":"publisher","first-page":"7021","DOI":"10.1523\/JNEUROSCI.0011-12.2012","article-title":"Laminarly orthogonal excitation of fast-spiking and low-threshold-spiking interneurons in mouse motor cortex","volume":"32","author":"Apicella","year":"2012","journal-title":"J. Neurosci"},{"key":"B3","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.neuron.2004.12.036","article-title":"Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo","volume":"45","author":"Arlotta","year":"2005","journal-title":"Neuron"},{"key":"B4","doi-asserted-by":"publisher","first-page":"7025","DOI":"10.1523\/JNEUROSCI.1954-08.2008","article-title":"A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping","volume":"28","author":"Atasoy","year":"2008","journal-title":"J. Neurosci"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1093\/brain\/awh550","article-title":"Motor neuron pathology in experimental autoimmune encephalomyelitis: studies in THY1-YFP transgenic mice","volume":"128","author":"Bannerman","year":"2005","journal-title":"Brain"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1038\/nm1331","article-title":"Transgenic labeling of the corticospinal tract for monitoring axonal responses to spinal cord injury","volume":"11","author":"Bareyre","year":"2005","journal-title":"Nat. Med"},{"key":"B7","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1523\/JNEUROSCI.01-02-00121.1981","article-title":"A comparison of the intranigral distribution of nigrotectal neurons labeled with horseradish peroxidase in the monkey, cat, and rat","volume":"1","author":"Beckstead","year":"1981","journal-title":"J. Neurosci"},{"key":"B8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0006-8993(80)90941-5","article-title":"Origin of the pyramidal tract determined with horseradish peroxidase","volume":"193","author":"Biedenbach","year":"1980","journal-title":"Brain Res"},{"key":"B9","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1111\/j.1471-4159.1977.tb07737.x","article-title":"Retrograde axonal transport of endogenous protein: differences between motor and sensory axons","volume":"28","author":"Bisby","year":"1977","journal-title":"J. Neurochem"},{"key":"B10","doi-asserted-by":"publisher","first-page":"e15477","DOI":"10.1371\/journal.pone.0015477","article-title":"Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice","volume":"5","author":"Bittner","year":"2010","journal-title":"PLoS ONE"},{"key":"B11","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.tins.2004.03.002","article-title":"Gene therapy for ALS delivers","volume":"27","author":"Boillee","year":"2004","journal-title":"Trends Neurosci"},{"key":"B12","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1002\/cne.901640402","article-title":"Olfactory relationships of the telencephalon and diencephalon in the rabbit. II. An autoradiographic and horseradish peroxidase study of the efferent connections of the anterior olfactory nucleus","volume":"164","author":"Broadwell","year":"1975","journal-title":"J. Comp. Neurol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1002\/(SICI)1096-9861(19970922)386:2%3C293::AID-CNE9%3E3.0.CO;2-X","article-title":"Cells of origin, course, and termination patterns of the ventral, uncrossed component of the mature rat corticospinal tract","volume":"386","author":"Brosamle","year":"1997","journal-title":"J. Comp. Neurol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1055\/s-2001-15260","article-title":"Amyotrophic lateral sclerosis: pathogenesis","volume":"21","author":"Brown","year":"2001","journal-title":"Semin. Neurol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1002\/cne.901640302","article-title":"Monkey retinal ganglion cells: morphometric analysis and tracing of axonal projections, with a consideration of the peroxidase technique","volume":"164","author":"Bunt","year":"1975","journal-title":"J. Comp. Neurol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/0006-8993(74)91045-2","article-title":"Retrograde axonal transport of horseradish peroxidase by ganglion cells of the albino rat retina","volume":"73","author":"Bunt","year":"1974","journal-title":"Brain Res"},{"key":"B17","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1089\/hum.2005.16.781","article-title":"Recombinant adeno-associated viral vectors in the nervous system","volume":"16","author":"Burger","year":"2005","journal-title":"Hum. Gene Ther"},{"key":"B18","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1038\/nmeth.2450","article-title":"Improved tools for the Brainbow toolbox","volume":"10","author":"Cai","year":"2013","journal-title":"Nat. Methods"},{"key":"B19","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/j.pneurobio.2008.02.001","article-title":"Molecular mechanisms of axon guidance in the developing corticospinal tract","volume":"85","author":"Canty","year":"2008","journal-title":"Prog. Neurobiol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1002\/cne.902780210","article-title":"Direct projection of the corticospinal tract to the superficial laminae of the spinal cord in the rat","volume":"278","author":"Casale","year":"1988","journal-title":"J. Comp. Neurol"},{"key":"B21","doi-asserted-by":"crossref","first-page":"8863","DOI":"10.1523\/JNEUROSCI.21-22-08863.2001","article-title":"Specific neurotrophic factors support the survival of cortical projection neurons at distinct stages of development","volume":"21","author":"Catapano","year":"2001","journal-title":"J. Neurosci"},{"key":"B22","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1385\/1-59259-186-8:299","article-title":"Neuroanatomical tracing of neuronal projections with Fluoro-Gold","volume":"198","author":"Catapano","year":"2002","journal-title":"Methods Mol. Biol"},{"key":"B23","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1002\/cne.901700405","article-title":"Interhemispheric neocortical connections of the corpus callosum in the reeler mutant mouse: a study based on anterograde and retrograde methods","volume":"170","author":"Caviness","year":"1976","journal-title":"J. Comp. Neurol"},{"key":"B24","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1126\/science.8303295","article-title":"Green fluorescent protein as a marker for gene expression","volume":"263","author":"Chalfie","year":"1994","journal-title":"Science"},{"key":"B25","doi-asserted-by":"publisher","first-page":"2815","DOI":"10.1523\/JNEUROSCI.2475-10.2011","article-title":"Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis","volume":"31","author":"Chang","year":"2011","journal-title":"J. Neurosci"},{"key":"B26","doi-asserted-by":"publisher","first-page":"9598","DOI":"10.1523\/JNEUROSCI.1851-04.2004","article-title":"Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period","volume":"24","author":"Chattopadhyaya","year":"2004","journal-title":"J. Neurosci"},{"key":"B27","doi-asserted-by":"publisher","first-page":"1524","DOI":"10.1111\/j.1460-9568.2012.08033.x","article-title":"Unveiling the diversity of thalamocortical neuron subtypes","volume":"35","author":"Clasca","year":"2012","journal-title":"Eur. J. Neurosci"},{"key":"B28","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1038\/nm1595","article-title":"Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans?","volume":"13","author":"Courtine","year":"2007","journal-title":"Nat. Med"},{"key":"B29","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/BF00236020","article-title":"Role of axonal transport in maintaining central synaptic connections","volume":"24","author":"Cull","year":"1975","journal-title":"Exp. Brain Res"},{"key":"B30","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.nbd.2013.12.011","article-title":"Enhanced ubiquitin-dependent degradation by Nedd4 protects against alpha-synuclein accumulation and toxicity in animal models of Parkinson's disease","volume":"64C","author":"Davies","year":"2013","journal-title":"Neurobiol. Dis"},{"key":"B31","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1002\/bies.201100098","article-title":"Fluorescent proteins for FRET microscopy: monitoring protein interactions in living cells","volume":"34","author":"Day","year":"2012","journal-title":"Bioessays"},{"key":"B32","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1016\/j.nbd.2011.12.013","article-title":"Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of alpha-synuclein in midbrain dopamine neurons","volume":"45","author":"Decressac","year":"2012","journal-title":"Neurobiol. Dis"},{"key":"B33","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/0304-3940(80)90247-5","article-title":"Double and triple labeling of neurons with fluorescent substances; the study of collateral pathways in the ascending raphe system","volume":"19","author":"De Olmos","year":"1980","journal-title":"Neurosci. Lett"},{"key":"B34","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/s00424-012-1175-y","article-title":"Multiplexed visualization of dynamic signaling networks using genetically encoded fluorescent protein-based biosensors","volume":"465","author":"Depry","year":"2013","journal-title":"Pflugers Arch"},{"key":"B35","doi-asserted-by":"publisher","first-page":"e82654","DOI":"10.1371\/journal.pone.0082654","article-title":"Selective vulnerability of spinal and cortical motor neuron subpopulations in delta7 SMA mice","volume":"8","author":"D'Errico","year":"2013","journal-title":"PLoS ONE"},{"key":"B36","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1038\/nn1885","article-title":"Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model","volume":"10","author":"Di Giorgio","year":"2007","journal-title":"Nat. Neurosci"},{"key":"B37","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1038\/mt.2008.60","article-title":"Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity","volume":"16","author":"Dodge","year":"2008","journal-title":"Mol. Ther"},{"key":"B38","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.neuron.2007.08.003","article-title":"Imaging large-scale neural activity with cellular resolution in awake, mobile mice","volume":"56","author":"Dombeck","year":"2007","journal-title":"Neuron"},{"key":"B39","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1016\/j.cell.2008.10.029","article-title":"Application of a translational profiling approach for the comparative analysis of CNS cell types","volume":"135","author":"Doyle","year":"2008","journal-title":"Cell"},{"key":"B40","doi-asserted-by":"publisher","first-page":"2150","DOI":"10.1016\/j.cub.2010.11.021","article-title":"GDNF acts as a chemoattractant to support ephrinA-induced repulsion of limb motor axons","volume":"20","author":"Dudanova","year":"2010","journal-title":"Curr. Biol"},{"key":"B41","doi-asserted-by":"publisher","first-page":"8294","DOI":"10.1523\/JNEUROSCI.2010-08.2008","article-title":"A novel purification method for CNS projection neurons leads to the identification of brain vascular cells as a source of trophic support for corticospinal motor neurons","volume":"28","author":"Dugas","year":"2008","journal-title":"J. Neurosci"},{"key":"B42","first-page":"292","article-title":"Adeno-associated virus vectors for gene therapy of neurodegenerative disorders","volume":"3","author":"During","year":"1995","journal-title":"Clin. Neurosci"},{"key":"B43","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1002\/mus.1042","article-title":"The motor cortex and amyotrophic lateral sclerosis","volume":"24","author":"Eisen","year":"2001","journal-title":"Muscle Nerve"},{"key":"B44","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/S0896-6273(00)00084-2","article-title":"Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP","volume":"28","author":"Feng","year":"2000","journal-title":"Neuron"},{"key":"B45","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1055\/s-2001-15265","article-title":"Progressive spastic paraparesis: hereditary spastic paraplegia and its relation to primary and amyotrophic lateral sclerosis","volume":"21","author":"Fink","year":"2001","journal-title":"Semin. Neurol"},{"key":"B46","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1523\/JNEUROSCI.4880-04.2005","article-title":"Polysialylated neural cell adhesion molecule is necessary for selective targeting of regenerating motor neurons","volume":"25","author":"Franz","year":"2005","journal-title":"J. Neurosci"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2013.10.014","article-title":"Moving forward in clinical trials for ALS: motor neurons lead the way please","author":"Gen\u00c3\u00a7","year":"2013","journal-title":"Drug Discov. Today"},{"key":"B48","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1016\/j.neuron.2013.10.016","article-title":"GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits","volume":"80","author":"Gerfen","year":"2013","journal-title":"Neuron"},{"key":"B49","doi-asserted-by":"publisher","first-page":"9817","DOI":"10.1523\/JNEUROSCI.2707-07.2007","article-title":"Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs","volume":"27","author":"Gong","year":"2007","journal-title":"J. Neurosci"},{"key":"B50","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1038\/nature02033","article-title":"A gene expression atlas of the central nervous system based on bacterial artificial chromosomes","volume":"425","author":"Gong","year":"2003","journal-title":"Nature"},{"key":"B51","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1038\/nature01276","article-title":"Long-term dendritic spine stability in the adult cortex","volume":"420","author":"Grutzendler","year":"2002","journal-title":"Nature"},{"key":"B52","doi-asserted-by":"publisher","first-page":"1772","DOI":"10.1126\/science.8209258","article-title":"Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation","volume":"264","author":"Gurney","year":"1994","journal-title":"Science"},{"key":"B53","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1038\/gt.2010.6","article-title":"Lack of humoral immune response to the tetracycline (Tet) activator in rats injected intracranially with Tet-off rAAV vectors","volume":"17","author":"Han","year":"2010","journal-title":"Gene Ther"},{"key":"B54","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1038\/287647a0","article-title":"Retrograde axonal transport of target tissue-derived macromolecules","volume":"287","author":"Hendry","year":"1980","journal-title":"Nature"},{"key":"B55","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1038\/mt.2010.271","article-title":"CNS-targeted viral delivery of G-CSF in an animal model for ALS: improved efficacy and preservation of the neuromuscular unit","volume":"19","author":"Henriques","year":"2011","journal-title":"Mol. Ther"},{"key":"B56","doi-asserted-by":"publisher","first-page":"428","DOI":"10.2174\/156652309789753383","article-title":"AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS","volume":"9","author":"Hester","year":"2009","journal-title":"Curr. Gene Ther"},{"key":"B57","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1146\/annurev-neuro-062012-170307","article-title":"Genetic approaches to neural circuits in the mouse","volume":"36","author":"Huang","year":"2013","journal-title":"Annu. Rev. Neurosci"},{"key":"B58","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1016\/j.neuron.2005.12.003","article-title":"Distinct roles for secreted semaphorin signaling in spinal motor axon guidance","volume":"48","author":"Huber","year":"2005","journal-title":"Neuron"},{"key":"B59","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/0006-8993(81)90153-0","article-title":"Quantitative differences in collateralization of the descending spinal pathways from red nucleus and other brain stem cell groups in rat as demonstrated with the multiple fluorescent retrograde tracer technique","volume":"209","author":"Huisman","year":"1981","journal-title":"Brain Res"},{"key":"B60","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1038\/gt.2011.71","article-title":"Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector","volume":"19","author":"Hutson","year":"2011","journal-title":"Gene Ther"},{"key":"B61","doi-asserted-by":"publisher","first-page":"3109","DOI":"10.3791\/3109","article-title":"Mapping inhibitory neuronal circuits by laser scanning photostimulation","volume":"pii","author":"Ikrar","year":"2011","journal-title":"J. Vis. Exp"},{"key":"B62","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.nbd.2012.03.036","article-title":"AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS","volume":"47","author":"Jara","year":"2012","journal-title":"Neurobiol. Dis"},{"key":"B63","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1002\/cne.901540402","article-title":"Retrograde axonal transport and the demonstration of non-specific projections to the cerebral cortex and striatum from thalamic intralaminar nuclei in the rat, cat and monkey","volume":"154","author":"Jones","year":"1974","journal-title":"J. Comp. Neurol"},{"key":"B64","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S0079-6123(08)64137-0","article-title":"Growth and maturation of the rat corticospinal tract","volume":"57","author":"Jones","year":"1982","journal-title":"Prog. Brain Res"},{"key":"B65","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1242\/dmm.002113","article-title":"Human embryonic stem cell-derived motor neurons expressing SOD1 mutants exhibit typical signs of motor neuron degeneration linked to ALS","volume":"2","author":"Karumbayaram","year":"2009","journal-title":"Dis. Model. Mech"},{"key":"B66","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1126\/science.1086137","article-title":"Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model","volume":"301","author":"Kaspar","year":"2003","journal-title":"Science"},{"key":"B67","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.pharmthera.2013.10.009","article-title":"Gene and protein therapies utilizing VEGF for ALS","volume":"141","author":"Keifer","year":"2014","journal-title":"Pharmacol. Ther"},{"key":"B68","doi-asserted-by":"publisher","first-page":"e38593","DOI":"10.1371\/journal.pone.0038593","article-title":"Genetic labeling of neuronal subsets through enhancer trapping in mice","volume":"7","author":"Kelsch","year":"2012","journal-title":"PLoS ONE"},{"key":"B69","doi-asserted-by":"publisher","first-page":"4992","DOI":"10.1523\/JNEUROSCI.4759-11.2012","article-title":"Hierarchical connectivity and connection-specific dynamics in the corticospinal-corticostriatal microcircuit in mouse motor cortex","volume":"32","author":"Kiritani","year":"2012","journal-title":"J. Neurosci"},{"key":"B70","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/0006-8993(74)90569-1","article-title":"Retrograde transport of horseradish peroxidase in transected axons. 1. Time relationships between transport and induction of chromatolysis","volume":"79","author":"Kristensson","year":"1974","journal-title":"Brain Res"},{"key":"B71","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/BF00237090","article-title":"Evidence for selective axon-terminal uptake and retrograde transport of label in cortico- and rubrospinal systems after injection of 3H-proline","volume":"28","author":"Kunzle","year":"1977","journal-title":"Exp. Brain Res"},{"key":"B72","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/BF00236147","article-title":"Double retrograde neuronal labeling through divergent axon collaterals, using two fluorescent tracers with the same excitation wavelength which label different features of the cell","volume":"40","author":"Kuypers","year":"1980","journal-title":"Exp. Brain Res"},{"key":"B73","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.jchemneu.2011.07.001","article-title":"A half century of experimental neuroanatomical tracing","volume":"42","author":"Lanciego","year":"2011","journal-title":"J. Chem. Neuroanat"},{"key":"B74","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1113\/jphysiol.1978.sp012546","article-title":"The development of motor projection patterns in the chick hind limb","volume":"284","author":"Landmesser","year":"1978","journal-title":"J. Physiol"},{"key":"B75","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1111\/j.1471-4159.2010.06806.x","article-title":"AAV-mediated expression of wild-type and ALS-linked mutant VAPB selectively triggers death of motoneurons through a Ca2+-dependent ER-associated pathway","volume":"114","author":"Langou","year":"2010","journal-title":"J. Neurochem"},{"key":"B76","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.expneurol.2012.07.007","article-title":"In vivo imaging: a dynamic imaging approach to study spinal cord regeneration","volume":"242","author":"Laskowski","year":"2013","journal-title":"Exp. Neurol"},{"key":"B77","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.1126\/science.176.4042.1416","article-title":"Retrograde axonal transport in the central nervous system","volume":"176","author":"Lavail","year":"1972","journal-title":"Science"},{"key":"B78","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1002\/cne.901570304","article-title":"The retrograde intraaxonal transport of horseradish peroxidase in the chick visual system: a light and electron microscopic study","volume":"157","author":"Lavail","year":"1974","journal-title":"J. Comp. Neurol"},{"key":"B79","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/0006-8993(73)90016-4","article-title":"A method based on retrograde intraaxonal transport of protein for identification of cell bodies of origin of axons terminating within the CNS","volume":"58","author":"Lavail","year":"1973","journal-title":"Brain Res"},{"key":"B80","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1038\/35065539","article-title":"Defining brain wiring patterns and mechanisms through gene trapping in mice","volume":"410","author":"Leighton","year":"2001","journal-title":"Nature"},{"key":"B81","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1146\/annurev.neuro.31.060407.125547","article-title":"Descending pathways in motor control","volume":"31","author":"Lemon","year":"2008","journal-title":"Annu. Rev. Neurosci"},{"key":"B82","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/s00429-010-0281-x","article-title":"Projections from the brain to the spinal cord in the mouse","volume":"215","author":"Liang","year":"2011","journal-title":"Brain Struct. Funct"},{"key":"B83","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1007\/BF00235012","article-title":"Projection of thalamic neurons to cat primary vestibular cortical fields studied by means of retrograde axonal transport of horseradish peroxidase","volume":"24","author":"Liedgren","year":"1976","journal-title":"Exp. Brain Res"},{"key":"B84","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1038\/nature11028","article-title":"Optogenetic stimulation of a hippocampal engram activates fear memory recall","volume":"484","author":"Liu","year":"2012","journal-title":"Nature"},{"key":"B85","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1038\/nature06293","article-title":"Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system","volume":"450","author":"Livet","year":"2007","journal-title":"Nature"},{"key":"B86","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1093\/cercor\/bhh072","article-title":"Preferential origin and layer destination of GAD65-GFP cortical interneurons","volume":"14","author":"Lopez-Bendito","year":"2004","journal-title":"Cereb. Cortex"},{"key":"B87","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/S0168-0102(02)00195-5","article-title":"Intramuscular injection of AAV-GDNF results in sustained expression of transgenic GDNF, and its delivery to spinal motoneurons by retrograde transport","volume":"45","author":"Lu","year":"2003","journal-title":"Neurosci. Res"},{"key":"B88","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.brainresrev.2007.01.012","article-title":"Fly MARCM and mouse MADM: genetic methods of labeling and manipulating single neurons","volume":"55","author":"Luo","year":"2007","journal-title":"Brain Res. Rev"},{"key":"B89","doi-asserted-by":"publisher","first-page":"14083","DOI":"10.1073\/pnas.94.25.14083","article-title":"Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats","volume":"94","author":"Mandel","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"B90","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1038\/nrn1519","article-title":"Interneurons of the neocortical inhibitory system","volume":"5","author":"Markram","year":"2004","journal-title":"Nat. Rev. Neurosci"},{"key":"B91","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s00429-002-0233-1","article-title":"Targeting functional subtypes of spinal motoneurons and skeletal muscle fibers in vivo by intramuscular injection of adenoviral and adeno-associated viral vectors","volume":"205","author":"Martinov","year":"2002","journal-title":"Anat Embryol. (Berl.)"},{"key":"B92","doi-asserted-by":"publisher","first-page":"333","DOI":"10.2174\/1566523054064995","article-title":"Adeno-associated virus (AAV) vectors in the CNS","volume":"5","author":"McCown","year":"2005","journal-title":"Curr. Gene Ther"},{"key":"B93","doi-asserted-by":"publisher","first-page":"2900","DOI":"10.1093\/hmg\/ddn189","article-title":"Embryonic motor axon development in the severe SMA mouse","volume":"17","author":"McGovern","year":"2008","journal-title":"Hum. Mol. Genet"},{"key":"B94","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1016\/S0140-6736(75)90364-5","article-title":"Clinical sign of obstructed axoplasmic transport","volume":"2","author":"McLeod","year":"1975","journal-title":"Lancet"},{"key":"B95","doi-asserted-by":"publisher","first-page":"7848","DOI":"10.1523\/JNEUROSCI.1972-04.2004","article-title":"Functional properties of motoneurons derived from mouse embryonic stem cells","volume":"24","author":"Miles","year":"2004","journal-title":"J. Neurosci"},{"key":"B96","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.neures.2006.02.008","article-title":"Towards the classification of subpopulations of layer V pyramidal projection neurons","volume":"55","author":"Molnar","year":"2006","journal-title":"Neurosci. Res"},{"key":"B97","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1038\/nrn2151","article-title":"Neuronal subtype specification in the cerebral cortex","volume":"8","author":"Molyneaux","year":"2007","journal-title":"Nat. Rev. Neurosci"},{"key":"B98","doi-asserted-by":"publisher","first-page":"12776","DOI":"10.1523\/JNEUROSCI.3463-09.2009","article-title":"Axonal transport defects in neurodegenerative diseases","volume":"29","author":"Morfini","year":"2009","journal-title":"J. Neurosci"},{"key":"B99","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1038\/nn1876","article-title":"Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons","volume":"10","author":"Nagai","year":"2007","journal-title":"Nat. Neurosci"},{"key":"B100","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1126\/science.1247363","article-title":"Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders","volume":"343","author":"Novarino","year":"2014","journal-title":"Science"},{"key":"B101","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1016\/0896-6273(93)90049-W","article-title":"Development of projection neuron types, axon pathways, and patterned connections of the mammalian cortex","volume":"10","author":"O'Leary","year":"1993","journal-title":"Neuron"},{"key":"B102","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1111\/j.1365-2990.1979.tb00636.x","article-title":"Uptake and retrograde axonal transport of horseradish peroxidase in normal and axotomized motor neurons during postnatal development","volume":"5","author":"Olsson","year":"1979","journal-title":"Neuropathol. Appl. Neurobiol"},{"key":"B103","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/0006-8993(75)90007-4","article-title":"The retrograde transport of horseradish peroxidase from the developing limb of the chick embryo","volume":"98","author":"Oppenheim","year":"1975","journal-title":"Brain Res"},{"key":"B104","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1016\/j.neuron.2004.12.001","article-title":"Dendritic spine dynamics are regulated by monocular deprivation and extracellular matrix degradation","volume":"44","author":"Oray","year":"2004","journal-title":"Neuron"},{"key":"B105","doi-asserted-by":"publisher","first-page":"4166","DOI":"10.1523\/JNEUROSCI.4184-10.2011","article-title":"Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G93A transgenic ALS mice","volume":"31","author":"Ozdinler","year":"2011","journal-title":"J. Neurosci"},{"key":"B106","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1038\/nn1789","article-title":"IGF-I specifically enhances axon outgrowth of corticospinal motor neurons","volume":"9","author":"Ozdinler","year":"2006","journal-title":"Nat. Neurosci"},{"key":"B107","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1038\/nn.3427","article-title":"Targeting neurons and photons for optogenetics","volume":"16","author":"Packer","year":"2013","journal-title":"Nat. Neurosci"},{"key":"B108","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/0006-8993(75)90982-8","article-title":"Biological importance of retrograde axonal transport of nerve growth factor in adrenergic neurons","volume":"84","author":"Paravicini","year":"1975","journal-title":"Brain Res"},{"key":"B109","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1038\/nn.2741","article-title":"Dendritic spine pathology in neuropsychiatric disorders","volume":"14","author":"Penzes","year":"2011","journal-title":"Nat. Neurosci"},{"key":"B110","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1016\/j.cell.2011.11.004","article-title":"Intravital imaging","volume":"147","author":"Pittet","year":"2011","journal-title":"Cell"},{"key":"B111","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1634\/stemcells.2008-0884","article-title":"BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage","volume":"27","author":"Placantonakis","year":"2009","journal-title":"Stem Cells"},{"key":"B112","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/0304-3940(77)90145-8","article-title":"Tetanus toxin: retrograde axonal transport of systemically administered toxin","volume":"4","author":"Price","year":"1977","journal-title":"Neurosci. Lett"},{"key":"B113","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1212\/01.wnl.0000260965.20021.47","article-title":"Focality of upper and lower motor neuron degeneration at the clinical onset of ALS","volume":"68","author":"Ravits","year":"2007","journal-title":"Neurology"},{"key":"B114","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1002\/cne.902000105","article-title":"Development of the pyramidal tract in the hamster. I. A light microscopic study","volume":"200","author":"Reh","year":"1981","journal-title":"J. Comp. Neurol"},{"key":"B115","doi-asserted-by":"publisher","first-page":"2222","DOI":"10.1002\/jnr.22053","article-title":"Corticospinal neurons respond differentially to neurotrophins and myelin-associated glycoprotein in vitro","volume":"87","author":"Richter","year":"2009","journal-title":"J. Neurosci. Res"},{"key":"B116","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1007\/BF00238364","article-title":"Corticospinal tract collaterals to the dorsal column nuclei of cats. An anatomical single and double retrograde tracer study","volume":"43","author":"Rustioni","year":"1981","journal-title":"Exp. Brain Res"},{"key":"B117","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1002\/cne.20620","article-title":"A compensatory subpopulation of motor neurons in a mouse model of amyotrophic lateral sclerosis","volume":"490","author":"Schaefer","year":"2005","journal-title":"J. Comp. Neurol"},{"key":"B118","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1101\/pdb.top073692","article-title":"BAC transgenic mice and the GENSAT database of engineered mouse strains","author":"Schmidt","year":"2013","journal-title":"Cold Spring Harb. Protoc"},{"key":"B119","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1083\/jcb.82.3.798","article-title":"Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport","volume":"82","author":"Schwab","year":"1979","journal-title":"J. Cell Biol"},{"key":"B120","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1038\/nmeth819","article-title":"A guide to choosing fluorescent proteins","volume":"2","author":"Shaner","year":"2005","journal-title":"Nat. Methods"},{"key":"B121","doi-asserted-by":"publisher","first-page":"2216","DOI":"10.1152\/jn.00232.2011","article-title":"Corticospinal-specific HCN expression in mouse motor cortex: I(h)-dependent synaptic integration as a candidate microcircuit mechanism involved in motor control","volume":"106","author":"Sheets","year":"2011","journal-title":"J. Neurophysiol"},{"issue":"30","key":"B122","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2011.00030","article-title":"The microcircuit concept applied to cortical evolution: from three-layer to six-layer cortex","volume":"5","author":"Shepherd","year":"2011","journal-title":"Front. Neuroanat"},{"key":"B123","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1038\/nrn3469","article-title":"Corticostriatal connectivity and its role in disease","volume":"14","author":"Shepherd","year":"2013","journal-title":"Nat. Rev. Neurosci"},{"key":"B124","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/0304-3940(81)90182-8","article-title":"Divergent projection of individual corticospinal axons to motoneurons of multiple muscles in the monkey","volume":"23","author":"Shinoda","year":"1981","journal-title":"Neurosci. Lett"},{"key":"B125","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/1749-8104-4-42","article-title":"Gamma motor neurons express distinct genetic markers at birth and require muscle spindle-derived GDNF for postnatal survival","volume":"4","author":"Shneider","year":"2009","journal-title":"Neural Dev"},{"key":"B126","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.expneurol.2005.06.021","article-title":"Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells","volume":"196","author":"Singh Roy","year":"2005","journal-title":"Exp. Neurol"},{"issue":"18","key":"B127","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2013.00018","article-title":"Tools, methods, and applications for optophysiology in neuroscience","volume":"6","author":"Smedemark-Margulies","year":"2013","journal-title":"Front. Mol. Neurosci"},{"key":"B128","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1089\/hum.2011.008","article-title":"Comparison of adeno-associated viral vector serotypes for spinal cord and motor neuron gene delivery","volume":"22","author":"Snyder","year":"2011","journal-title":"Hum. Gene Ther"},{"key":"B129","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/0014-4886(78)90241-8","article-title":"Identification of the trochlear motoneurons by retrograde transport of horseradish peroxidase","volume":"59","author":"Sohal","year":"1978","journal-title":"Exp. Neurol"},{"key":"B130","doi-asserted-by":"publisher","first-page":"1805","DOI":"10.1016\/0306-4522(79)90059-9","article-title":"An approach to tracing neuron networks in the cerebral cortex and basal ganglia. Combination of Golgi staining, retrograde transport of horseradish peroxidase and anterograde degeneration of synaptic boutons in the same material","volume":"4","author":"Somogyi","year":"1979","journal-title":"Neuroscience"},{"key":"B131","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/0301-0082(92)90039-H","article-title":"The development of the corticospinal projection","volume":"38","author":"Stanfield","year":"1992","journal-title":"Prog. Neurobiol"},{"key":"B132","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/0006-8993(78)90387-6","article-title":"Relationship between motoneurons and internuclear neurons in the abducens nucleus: a double retrograde tracer study in the cat","volume":"148","author":"Steiger","year":"1978","journal-title":"Brain Res"},{"key":"B133","doi-asserted-by":"publisher","first-page":"313","DOI":"10.2144\/000113765","article-title":"Modern fluorescent proteins: from chromophore formation to novel intracellular applications","volume":"51","author":"Stepanenko","year":"2011","journal-title":"Biotechniques"},{"key":"B134","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/0006-8993(75)90092-X","article-title":"Retrograde axonal transport of nerve growth factor: specificity and biological importance","volume":"85","author":"Stoeckel","year":"1975","journal-title":"Brain Res"},{"key":"B135","doi-asserted-by":"publisher","first-page":"1965","DOI":"10.1093\/cercor\/bhs184","article-title":"Intrinsic electrophysiology of mouse corticospinal neurons: a class-specific triad of spike-related properties","volume":"23","author":"Suter","year":"2012","journal-title":"Cereb. Cortex"},{"issue":"12","key":"B136","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2011.00012","article-title":"Local connections of layer 5 GABAergic interneurons to corticospinal neurons","volume":"5","author":"Tanaka","year":"2011","journal-title":"Front. Neural Circuits"},{"key":"B137","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1016\/j.cell.2013.07.021","article-title":"A nanobody-based system using fluorescent proteins as scaffolds for cell-specific gene manipulation","volume":"154","author":"Tang","year":"2013","journal-title":"Cell"},{"key":"B138","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/j.neuron.2011.07.026","article-title":"A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex","volume":"71","author":"Taniguchi","year":"2011","journal-title":"Neuron"},{"key":"B139","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1038\/mt.2009.3","article-title":"Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression","volume":"17","author":"Tatom","year":"2009","journal-title":"Mol. Ther"},{"key":"B140","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/0168-0102(95)00895-9","article-title":"Anatomy, development and lesion-induced plasticity of rodent corticospinal tract","volume":"22","author":"Terashima","year":"1995","journal-title":"Neurosci. Res"},{"key":"B141","doi-asserted-by":"publisher","first-page":"2","DOI":"10.3389\/neuro.01.1.1.002.2007","article-title":"Functional maps of neocortical local circuitry","volume":"1","author":"Thomson","year":"2007","journal-title":"Front. Neurosci"},{"key":"B142","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1002\/cne.901820104","article-title":"Organizational features of the cat and monkey cerebellar nucleocortical projection","volume":"182","author":"Tolbert","year":"1978","journal-title":"J. Comp. Neurol"},{"key":"B143","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1038\/mt.2010.260","article-title":"Neuroprotection by gene therapy targeting mutant SOD1 in individual pools of motor neurons does not translate into therapeutic benefit in fALS mice","volume":"19","author":"Towne","year":"2011","journal-title":"Mol. Ther"},{"key":"B144","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1146\/annurev.biochem.67.1.509","article-title":"The green fluorescent protein","volume":"67","author":"Tsien","year":"1998","journal-title":"Annu. Rev. Biochem"},{"key":"B145","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/BF00686086","article-title":"Degeneration of Betz cells in motor neuron disease","volume":"70","author":"Udaka","year":"1986","journal-title":"A Golgi study. Acta Neuropathol"},{"key":"B146","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/0304-3940(81)90049-5","article-title":"Somatotopy of the corticospinal neurons in the rat","volume":"21","author":"Ullan","year":"1981","journal-title":"Neurosci. Lett"},{"key":"B147","doi-asserted-by":"crossref","first-page":"10640","DOI":"10.1523\/JNEUROSCI.18-24-10640.1998","article-title":"Selective neuronal expression of green fluorescent protein with cytomegalovirus promoter reveals entire neuronal arbor in transgenic mice","volume":"18","author":"van den Pol","year":"1998","journal-title":"J. Neurosci"},{"key":"B148","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1126\/science.441742","article-title":"Fluorescent retrograde double labeling: axonal branching in the ascending raphe and nigral projections","volume":"204","author":"van der Kooy","year":"1979","journal-title":"Science"},{"key":"B149","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/BF00235005","article-title":"A note on the method of retrograde transport of horseradish peroxidase as a tool in studies of afferent cerebellar connections, particularly those from the inferior olive; with comments on the orthograde transport in Purkinje cell axons","volume":"24","author":"Walberg","year":"1976","journal-title":"Exp. Brain Res"},{"key":"B150","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1038\/sj.gt.3301682","article-title":"Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease","volume":"9","author":"Wang","year":"2002a","journal-title":"Gene Ther"},{"key":"B151","doi-asserted-by":"crossref","first-page":"6920","DOI":"10.1523\/JNEUROSCI.22-16-06920.2002","article-title":"Neuroprotective effects of glial cell line-derived neurotrophic factor mediated by an adeno-associated virus vector in a transgenic animal model of amyotrophic lateral sclerosis","volume":"22","author":"Wang","year":"2002b","journal-title":"J. Neurosci"},{"key":"B152","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1083\/jcb.201212130","article-title":"Imaging cell biology in live animals: ready for prime time","volume":"201","author":"Weigert","year":"2013","journal-title":"J. Cell Biol"},{"key":"B153","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.neuropharm.2012.03.004","article-title":"Adeno-associated virus (AAV) gene therapy for neurological disease","volume":"69","author":"Weinberg","year":"2013","journal-title":"Neuropharmacology"},{"key":"B154","doi-asserted-by":"publisher","first-page":"1977","DOI":"10.1021\/nn800671h","article-title":"2008 Nobel Prize in Chemistry: green fluorescent protein, its variants and implications","volume":"2","author":"Weiss","year":"2008","journal-title":"ACS Nano"},{"key":"B155","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/S0092-8674(02)00835-8","article-title":"Directed differentiation of embryonic stem cells into motor neurons","volume":"110","author":"Wichterle","year":"2002","journal-title":"Cell"},{"key":"B156","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1002\/cne.901680302","article-title":"The organization and postnatal development of the commissural projection of the rat somatic sensory cortex","volume":"168","author":"Wise","year":"1976","journal-title":"J. Comp. Neurol"},{"key":"B157","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.mcn.2009.08.002","article-title":"Axonal and neuromuscular synaptic phenotypes in Wld(S), SOD1(G93A) and ostes mutant mice identified by fiber-optic confocal microendoscopy","volume":"42","author":"Wong","year":"2009","journal-title":"Mol. Cell. Neurosci"},{"key":"B158","doi-asserted-by":"publisher","first-page":"e3813","DOI":"10.3791\/3813","article-title":"Efficient differentiation of mouse embryonic stem cells into motor neurons","author":"Wu","year":"2012","journal-title":"J. Vis. Exp"},{"key":"B159","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1002\/emmm.201302935","article-title":"Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons","volume":"5","author":"Yamashita","year":"2013","journal-title":"EMBO Mol. Med"},{"key":"B160","doi-asserted-by":"publisher","first-page":"7890","DOI":"10.1523\/JNEUROSCI.2787-12.2013","article-title":"eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model","volume":"33","author":"Yasvoina","year":"2013","journal-title":"J. Neurosci"},{"key":"B161","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1002\/cne.901640206","article-title":"Interhemispheric neocortical connections of the corpus callosum in the normal mouse: a study based on anterograde and retrograde methods","volume":"164","author":"Yorke","year":"1975","journal-title":"J. Comp. Neurol"},{"key":"B162","doi-asserted-by":"publisher","first-page":"6","DOI":"10.3389\/neuro.04.006.2008","article-title":"Local-circuit phenotypes of layer 5 neurons in motor-frontal cortex of YFP-H mice","volume":"2","author":"Yu","year":"2008","journal-title":"Front. Neural Circuits"}],"container-title":["Frontiers in Neuroanatomy"],"original-title":[],"deposited":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T18:58:53Z","timestamp":1565290733000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fnana.2014.00016\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,26]]},"references-count":162,"URL":"https:\/\/doi.org\/10.3389\/fnana.2014.00016","relation":{},"ISSN":["1662-5129"],"issn-type":[{"value":"1662-5129","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,26]]}}}