{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T14:36:30Z","timestamp":1782311790773,"version":"3.54.5"},"reference-count":55,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T00:00:00Z","timestamp":1540771200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Behav. Neurosci."],"DOI":"10.3389\/fnbeh.2018.00235","type":"journal-article","created":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T04:57:09Z","timestamp":1540789029000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":30,"title":["Behavioral and Neurophysiological Effects of Transcranial Direct Current Stimulation (tDCS) in Fronto-Temporal Dementia"],"prefix":"10.3389","volume":"12","author":[{"given":"Roberta","family":"Ferrucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Mrakic-Sposta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Gardini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana","family":"Ruggiero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Vergari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Mameli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Arighi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Spallazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Barocco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Michelini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Margherita","family":"Pietroboni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Ghezzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio Giulio","family":"Fumagalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giordano","family":"D'Urso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Caffarra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elio","family":"Scarpini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Priori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Marceglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,10,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.ajp.2016.02.007","article-title":"Use of transcranial direct current stimulation (tDCS) in a woman with behavioral variant fronto-temporal dementia","volume":"21","author":"Agarwal","year":"2016","journal-title":"Asian J. Psychiatr."},{"key":"B2","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1002\/hup.472","article-title":"Drug therapy of frontotemporal dementia","volume":"18","author":"Allain","year":"2003","journal-title":"Hum. Psychopharmacol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"2888","DOI":"10.1111\/j.1460-9568.2004.03367.x","article-title":"Facilitation of visuo-motor learning by transcranial direct current stimulation of the motor and extrastriate visual areas in humans","volume":"19","author":"Antal","year":"2004","journal-title":"Eur. J. Neurosci."},{"key":"B4","doi-asserted-by":"publisher","first-page":"2687","DOI":"10.1111\/j.1460-9568.2007.05896.x","article-title":"Towards unravelling task-related modulations of neuroplastic changes induced in the human motor cortex","volume":"26","author":"Antal","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"B5","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/BF00831566","article-title":"A normative study on visual reaction times and two Stroop colour-word tests","volume":"19","author":"Barbarotto","year":"1998","journal-title":"Ital. J. Neurol. Sci."},{"key":"B6","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1098\/rstb.2011.0374","article-title":"Perceptuo-motor interactions in the perceptual organization of speech: evidence from the verbal transformation effect","volume":"367","author":"Basirat","year":"2012","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"B7","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.brs.2011.06.006","article-title":"Prolonged visual memory enhancement after direct current stimulation in Alzheimer's disease","volume":"5","author":"Boggio","year":"2012","journal-title":"Brain Stimul."},{"key":"B8","doi-asserted-by":"publisher","first-page":"e4959","DOI":"10.1371\/journal.pone.0004959","article-title":"Temporal lobe cortical electrical stimulation during the encoding and retrieval phase reduces false memories","volume":"4","author":"Boggio","year":"2009","journal-title":"PLoS ONE"},{"key":"B9","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1136\/jnnp.57.4.416","article-title":"Clinical and neuropathological criteria for frontotemporal dementia","volume":"57","author":"Brun","year":"1994","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"B10","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.brs.2011.03.002","article-title":"Clinical research with transcranial direct current stimulation (tDCS): challenges and future directions","volume":"5","author":"Brunoni","year":"2011","journal-title":"Brain Stimul."},{"key":"B11","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1590\/1414-431X20133115","article-title":"Neuromodulation approaches for the treatment of major depression: challenges and recommendations from a working group meeting","volume":"68","author":"Brunoni","year":"2010","journal-title":"Arq. Neuropsiquiatr."},{"key":"B12","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1159\/000119375","article-title":"Correlations of topographical EEG features with clinical severity in mild and moderate dementia of Alzheimer type","volume":"36","author":"Chiaramonti","year":"1997","journal-title":"Neuropsychobiology"},{"key":"B13","doi-asserted-by":"publisher","first-page":"799","DOI":"10.3233\/JAD-131427","article-title":"Treatment of primary progressive aphasias by transcranial direct current stimulation combined with language training","volume":"39","author":"Cotelli","year":"2014","journal-title":"J. Alzheimers Dis."},{"key":"B14","doi-asserted-by":"publisher","first-page":"640","DOI":"10.3758\/s13423-015-0913-5","article-title":"Hidden multiplicity in exploratory multiway ANOVA: Prevalence and remedies","volume":"23","author":"Cramer","year":"2016","journal-title":"Psychon. Bull. Rev."},{"key":"B15","doi-asserted-by":"publisher","first-page":"2308","DOI":"10.1016\/j.acn.2005.04.011","article-title":"The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia","volume":"44","author":"Cummings","year":"1994","journal-title":"Neurology"},{"key":"B16","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jneumeth.2003.10.009","article-title":"EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis","volume":"134","author":"Delorme","year":"2004","journal-title":"J. Neurosci. Methods"},{"key":"B17","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1002\/ana.410160404","article-title":"Brain electrical activity in patients with presenile and senile dementia of the Alzheimer type","volume":"16","author":"Duffy","year":"1984","journal-title":"Ann. Neurol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jad.2017.05.019","article-title":"Clinical predictors of acute response to transcranial direct current stimulation (tDCS) in major depression","volume":"219","author":"D'Urso","year":"2017","journal-title":"J. Affect. Disord."},{"key":"B19","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1097\/YCT.0000000000000538","article-title":"Transcranial direct current stimulation in obsessive-compulsive disorder, posttraumatic stress disorder, and anxiety disorders","volume":"34","author":"D'Urso","year":"2018","journal-title":"J. ECT"},{"key":"B20","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1186\/s13195-014-0074-1","article-title":"Transcranial magnetic stimulation and transcranial direct current stimulation: treatments for cognitive and neuropsychiatric symptoms in the neurodegenerative dementias?","volume":"6","author":"Elder","year":"2014","journal-title":"Alzheimers. Res. Ther."},{"key":"B21","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1212\/01.wnl.0000317060.43722.a3","article-title":"Transcranial direct current stimulation improves recognition memory in Alzheimer disease","volume":"71","author":"Ferrucci","year":"2008","journal-title":"Neurology"},{"key":"B22","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1016\/j.neuroimage.2013.05.098","article-title":"tDCS-enhanced motor and cognitive function in neurological diseases","volume":"85","author":"Floel","year":"2014","journal-title":"Neuroimage"},{"key":"B23","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1590\/0004-282X20150035","article-title":"Coherence of brain electrical activity: a quality of life indicator in Alzheimer's disease? Coer\u00eancia da atividade el\u00e9trica cerebral: indicador da qualidade de vida na doen\u00e7a de Alzheimer?","volume":"73","author":"Fonseca","year":"2015","journal-title":"Arq. Neuropsiquiatr."},{"key":"B24","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1177\/0891988708320973","article-title":"Reaction times and performance variability in normal aging, mild cognitive impairment, and Alzheimer's disease","volume":"21","author":"Gorus","year":"2008","journal-title":"J. Geriatr. Psychiatry Neurol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"263","DOI":"10.3233\/JAD-150791","article-title":"Measuring information processing speed in mild cognitive impairment: clinical versus research dichotomy","volume":"51","author":"Haworth","year":"2016","journal-title":"J. Alzheimers. Dis."},{"key":"B26","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1016\/j.clinph.2007.02.026","article-title":"No effect of DC brain polarization on verbal fluency in patients with advanced frontotemporal dementia","volume":"118","author":"Huey","year":"2007","journal-title":"Clin. Neurophysiol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/S0197-4580(00)00153-6","article-title":"Quantitative electroencephalography in mild cognitive impairment: longitudinal changes and possible prediction of Alzheimer's disease","volume":"21","author":"Jelic","year":"2000","journal-title":"Neurobiol. Aging"},{"key":"B28","doi-asserted-by":"publisher","first-page":"e50425","DOI":"10.1371\/journal.pone.0050425","article-title":"Cognitive processing speed in older adults: relationship with white matter integrity","volume":"7","author":"Kerchner","year":"2012","journal-title":"PLoS ONE"},{"key":"B29","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1017\/S0317167100021053","article-title":"Frontal behavioral inventory: diagnostic criteria for frontal lobe dementia","volume":"24","author":"Kertesz","year":"1997","journal-title":"Can. J. Neurol. Sci."},{"key":"B30","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0165-0173(98)00056-3","article-title":"EEG alpha and theta oscillations reflect cognitive and memory performance: a review and analysis","volume":"29","author":"Klimesch","year":"1999","journal-title":"Brain Res. Brain Res. Rev."},{"key":"B31","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1177\/1550059412475291","article-title":"Clinical advantages of quantitative electroencephalogram (QEEG)-electrical neuroimaging application in general neurology practice","volume":"44","author":"Koberda","year":"2013","journal-title":"Clin. EEG Neurosci."},{"key":"B32","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.jagp.2015.12.005","article-title":"Reaction time measures predict incident dementia in community-living older adults: the sydney memory and ageing study","volume":"24","author":"Kochan","year":"2016","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"B33","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.1016\/j.neuroimage.2009.09.052","article-title":"Processing speed is correlated with cerebral health markers in the frontal lobes as quantified by neuroimaging","volume":"49","author":"Kochunov","year":"2010","journal-title":"Neuroimage"},{"key":"B34","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1142\/S0129065707000932","article-title":"Synchronization measures of the scalp electroencephalogram can discriminate healthy from Alzheimer's subjects","volume":"17","author":"Kramer","year":"2007","journal-title":"Int. J. Neural Syst."},{"key":"B35","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1016\/j.neuroimage.2013.05.117","article-title":"Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases","volume":"85","author":"Kuo","year":"2014","journal-title":"Neuroimage"},{"key":"B36","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.clinph.2016.10.087","article-title":"Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)","volume":"128","author":"Lefaucheur","year":"2017","journal-title":"Clin. Neurophysiol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3389\/fnagi.2015.00049","article-title":"Anodal transcranial direct current stimulation of parietal cortex enhances action naming in Corticobasal Syndrome","volume":"7","author":"Manenti","year":"2015","journal-title":"Front. Aging Neurosci."},{"key":"B38","doi-asserted-by":"publisher","first-page":"134","DOI":"10.3389\/fnins.2016.00134","article-title":"Transcranial direct current stimulation modulates cortical neuronal activity in Alzheimer's disease","volume":"10","author":"Marceglia","year":"2016","journal-title":"Front. Neurosci."},{"key":"B39","doi-asserted-by":"publisher","first-page":"611","DOI":"10.3389\/fnhum.2015.00611","article-title":"Apathy in frontotemporal degeneration: neuroanatomical evidence of impaired goal-directed behavior","volume":"9","author":"Massimo","year":"2015","journal-title":"Front. Hum. Neurosci."},{"key":"B40","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1162\/089892903321662994","article-title":"Facilitation of implicit motor learning by weak transcranial direct current stimulation of the primary motor cortex in the human","volume":"15","author":"Nitsche","year":"2003","journal-title":"Cogn. Neurosci."},{"key":"B41","first-page":"477","article-title":"Tre test clinici di ricerca e produzione lessicale. Taratura su soggetti normali","volume":"47","author":"Novelli","year":"1986","journal-title":"Arch. Psicol. Neurol. Psichiatr."},{"key":"B42","doi-asserted-by":"publisher","first-page":"e65712","DOI":"10.1371\/journal.pone.0065712","article-title":"Intra-individual reaction time variability in mild cognitive impairment and Alzheimer's disease: gender, processing load and speed factors","volume":"8","author":"Phillips","year":"2013","journal-title":"PLoS ONE"},{"key":"B43","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1590\/S1980-57642013DN70100003","article-title":"Behavioural-variant frontotemporal dementia: an update","volume":"7","author":"Piguet","year":"2013","journal-title":"Dement. Neuropsychol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.trci.2017.03.003","article-title":"Inferior parietal transcranial direct current stimulation with training improves cognition in anomic Alzheimer's disease and frontotemporal dementia","volume":"3","author":"Roncero","year":"2017","journal-title":"Alzheimers Dement (N Y)."},{"key":"B45","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1093\/oso\/9780198299837.003.0012","article-title":"Phonology in a theory of perception-for-action-control","volume-title":"Phonetics, Phonology and Cognition","author":"Schwartz","year":"2002"},{"key":"B46","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.brs.2013.12.008","article-title":"Concurrent cognitive control training augments the antidepressant efficacy of tDCS: a pilot study","volume":"7","author":"Segrave","year":"2014","journal-title":"Brain Stimul."},{"key":"B47","doi-asserted-by":"publisher","first-page":"841","DOI":"10.2165\/11640070-000000000-00000","article-title":"Frontotemporal lobar degeneration: epidemiology, pathology, diagnosis and management","volume":"26","author":"Seltman","year":"2012","journal-title":"CNS Drugs"},{"key":"B48","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.neuropsychologia.2015.02.002","article-title":"Transcranial direct current stimulation (tDCS)\u2013application in neuropsychology","volume":"69","author":"Shin","year":"2015","journal-title":"Neuropsychologia"},{"key":"B49","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.arr.2015.11.004","article-title":"Does transcranial direct current stimulation enhance cognitive and motor functions in the ageing brain? A systematic review and meta-analysis","volume":"25","author":"Summers","year":"2016","journal-title":"Ageing Res. Rev"},{"key":"B50","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1515\/CCLM.2011.086","article-title":"Tau and p-tau as CSF biomarkers in dementia: a meta-analysis","volume":"49","author":"van Harten","year":"2011","journal-title":"Clin. Chem. Lab. Med."},{"key":"B51","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/S0304-3940(00)01036-3","article-title":"Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization","volume":"285","author":"Vanmechelen","year":"2000","journal-title":"Neurosci. Lett."},{"key":"B52","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/S0010-9452(08)70142-4","article-title":"A new standardized set of ecological pictures for experimental and clinical research on visual object processing","volume":"40","author":"Viggiano","year":"2004","journal-title":"Cortex"},{"key":"B53","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1111\/ejn.12916","article-title":"Anodal transcranial direct current stimulation over premotor cortex facilitates observational learning of a motor sequence","volume":"41","author":"Wade","year":"2015","journal-title":"Eur. J. Neurosci."},{"key":"B54","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1016\/j.clinph.2015.11.012","article-title":"A technical guide to tDCS, and related non-invasive brain stimulation tools","volume":"127","author":"Woods","year":"2016","journal-title":"Clin. Neurophysiol."},{"key":"B55","volume-title":"The Memory and Behavior Problems Checklist and the Burden Interview.","author":"Zarit","year":"1990"}],"container-title":["Frontiers in Behavioral Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fnbeh.2018.00235\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T21:00:58Z","timestamp":1720731658000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fnbeh.2018.00235\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,29]]},"references-count":55,"alternative-id":["10.3389\/fnbeh.2018.00235"],"URL":"https:\/\/doi.org\/10.3389\/fnbeh.2018.00235","relation":{},"ISSN":["1662-5153"],"issn-type":[{"value":"1662-5153","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,29]]},"article-number":"235"}}