{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T10:02:58Z","timestamp":1792058578458,"version":"4.4.0"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T00:00:00Z","timestamp":1543276800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Behav. Neurosci."],"DOI":"10.3389\/fnbeh.2018.00289","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T09:33:36Z","timestamp":1543311216000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":153,"title":["Is Empathy for Pain Unique in Its Neural Correlates? A Meta-Analysis of Neuroimaging Studies of Empathy"],"prefix":"10.3389","volume":"12","author":[{"given":"Inge","family":"Timmers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna L.","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molly D.","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corey A.","family":"Kronman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren C.","family":"Heathcote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Maya","family":"Hernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura E.","family":"Simons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,11,27]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1080\/17470919.2010.547085","article-title":"Mirror neuron system involvement in empathy: a critical look at the evidence","volume":"6","author":"Baird","year":"2011","journal-title":"Soc. Neurosci."},{"key":"B2","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1523\/JNEUROSCI.4012-07.2008","article-title":"Does it look painful or disgusting? Ask your parietal and cingulate cortex","volume":"28","author":"Benuzzi","year":"2008","journal-title":"J. Neurosci."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1146\/annurev-neuro-062111-150536","article-title":"The neural basis of empathy","volume":"35","author":"Bernhardt","year":"2012","journal-title":"Annu. Rev. Neurosci."},{"key":"B4","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.brainres.2013.01.009","article-title":"Vasopressin modulates neural responses related to emotional stimuli in the right amygdala","volume":"1499","author":"Brunnlieb","year":"2013","journal-title":"Brain Res."},{"key":"B5","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1007\/s00429-012-0380-y","article-title":"Parsing the neural correlates of moral cognition: ALE meta-analysis on morality, theory of mind, and empathy","volume":"217","author":"Bzdok","year":"2012","journal-title":"Brain Struct. Funct."},{"key":"B6","doi-asserted-by":"publisher","first-page":"17996","DOI":"10.1523\/JNEUROSCI.2686-11.2011","article-title":"Felt and seen pain evoke the same local patterns of cortical activity in insular and cingulate cortex","volume":"31","author":"Corradi-Dell'acqua","year":"2011","journal-title":"J. Neurosci."},{"key":"B7","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1038\/nrn2555","article-title":"How do you feel\u2013now? The anterior insula and human awareness","volume":"10","author":"Craig","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"B8","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1111\/j.1749-6632.2011.05990.x","article-title":"Significance of the insula for the evolution of human awareness of feelings from the body","volume":"1225","author":"Craig","year":"2011","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"B9","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1038\/nn1176","article-title":"Neural systems supporting interoceptive awareness","volume":"7","author":"Critchley","year":"2004","journal-title":"Nat. Neurosci."},{"key":"B10","doi-asserted-by":"publisher","first-page":"S33","DOI":"10.1016\/S1090-3801(09)60086-0","article-title":"Can we share a pain we never felt? Neural correlates of empathy in patients with congenital insensitivity to pain","volume":"13","author":"Danziger","year":"2009","journal-title":"Eur. J. Pain"},{"key":"B11","volume-title":"Empathy: A Social Psychological Approach.","author":"Davis","year":"1994"},{"key":"B12","doi-asserted-by":"publisher","first-page":"20150077","DOI":"10.1098\/rstb.2015.0077","article-title":"Empathy as a driver of prosocial behaviour: highly conserved neurobehavioural mechanisms across species","volume":"371","author":"Decety","year":"2016","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1100\/tsw.2006.221","article-title":"Human empathy through the lens of social neuroscience","volume":"6","author":"Decety","year":"2006","journal-title":"Sci. World J."},{"key":"B14","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/j.tics.2003.10.004","article-title":"Shared representations between self and others: a social cognitive neuroscience view","volume":"7","author":"Decety","year":"2003","journal-title":"Trends Cogn. Sci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.neulet.2017.06.058","article-title":"Neural functional correlates of empathic face processing","volume":"655","author":"Del Casale","year":"2017","journal-title":"Neurosci. Lett."},{"key":"B16","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.1016\/j.neuroimage.2011.09.017","article-title":"Activation likelihood estimation meta-analysis revisited","volume":"59","author":"Eickhoff","year":"2012","journal-title":"Neuroimage"},{"key":"B17","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/j.neuroimage.2011.05.021","article-title":"Co-activation patterns distinguish cortical modules, their connectivity and functional differentiation","volume":"57","author":"Eickhoff","year":"2011","journal-title":"Neuroimage"},{"key":"B18","doi-asserted-by":"publisher","first-page":"2907","DOI":"10.1002\/hbm.20718","article-title":"Coordinate-based activation likelihood estimation meta-analysis of neuroimaging data: a random-effects approach based on empirical estimates of spatial uncertainty","volume":"30","author":"Eickhoff","year":"2009","journal-title":"Hum. Brain Mapp."},{"key":"B19","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1016\/j.neubiorev.2010.10.009","article-title":"Is there a core neural network in empathy? An fMRI based quantitative meta-analysis","volume":"35","author":"Fan","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B20","doi-asserted-by":"publisher","first-page":"S29","DOI":"10.1016\/j.pain.2013.09.001","article-title":"Pain matrices and neuropathic pain matrices: a review","volume":"154","author":"Garcia-Larrea","year":"2013","journal-title":"Pain"},{"key":"B21","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1111\/1467-8721.ep10770953","article-title":"Emotional contagion","volume":"2","author":"Hatfield","year":"1993","journal-title":"Curr. Dir. Psychol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0304-3959(02)00101-X","article-title":"Pain and negative emotions in the face: judgements by health care professionals","volume":"99","author":"Kappesser","year":"2002","journal-title":"Pain"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1097\/j.pain.0000000000001257","article-title":"Pain as a threat to the social self: a motivational account","volume":"159","author":"Karos","year":"2018","journal-title":"Pain"},{"key":"B24","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/S0079-6123(06)56021-2","article-title":"Towards a unifying neural theory ofsocial cognition","volume":"156","author":"Keysers","year":"2006","journal-title":"Prog. Brain Res."},{"key":"B25","doi-asserted-by":"publisher","first-page":"2492","DOI":"10.1016\/j.neuroimage.2010.10.014","article-title":"Meta-analytic evidence for common and distinct neural networks associated with directly experienced pain and empathy for pain","volume":"54","author":"Lamm","year":"2011","journal-title":"Neuroimage"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2017.06.054","article-title":"Imaging empathy and prosocial emotions","author":"Lamm","year":"2017","journal-title":"Neurosci. Lett"},{"key":"B27","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.cortex.2015.01.021","article-title":"Distinct neural networks underlying empathy for pleasant and unpleasant touch","volume":"70","author":"Lamm","year":"2015","journal-title":"Cortex"},{"key":"B28","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1016\/j.tics.2004.10.001","article-title":"Core mechanisms in \u201ctheory of mind\u201d","volume":"8","author":"Leslie","year":"2004","journal-title":"Trends Cogn. Sci."},{"key":"B29","doi-asserted-by":"publisher","first-page":"2214","DOI":"10.1093\/cercor\/bhl129","article-title":"The sight of others' pain modulates motor processing in human cingulate cortex","volume":"17","author":"Morrison","year":"2007","journal-title":"Cereb. Cortex"},{"key":"B30","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/S0987-7053(00)00227-6","article-title":"Functional imaging of brain responses to pain: a review and meta-analysis","volume":"30","author":"Peyron","year":"2000","journal-title":"Neuropsychol. Clin."},{"key":"B31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/S0140525X02000018","article-title":"Empathy: its ultimate and proximate bases","volume":"25","author":"Preston","year":"2002","journal-title":"Behav. Brain Sci."},{"key":"B32","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1152\/physrev.00009.2013","article-title":"Cortical mechanisms underlying the organization of goal-directed actions and mirror neuron-based action understanding","volume":"94","author":"Rizzolatti","year":"2014","journal-title":"Physiol. Rev."},{"key":"B33","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1146\/annurev.neuro.27.070203.144230","article-title":"The mirror-neuron system","volume":"27","author":"Rizzolatti","year":"2004","journal-title":"Annu. Rev. Neurosci."},{"key":"B34","doi-asserted-by":"publisher","first-page":"2155","DOI":"10.1111\/ejn.12978","article-title":"Individual left-hand and right-hand intra-digit representations in human primary somatosensory cortex","volume":"42","author":"Schweisfurth","year":"2015","journal-title":"Eur. J. Neurosci."},{"key":"B35","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.pain.2006.08.033","article-title":"Brain responses to dynamic facial expressions of pain","volume":"126","author":"Simon","year":"2006","journal-title":"Pain"},{"key":"B36","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.neubiorev.2016.06.020","article-title":"Circles of engagement: childhood pain and parent brain","volume":"68","author":"Simons","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B37","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1111\/j.1749-6632.2009.04418.x","article-title":"The social neuroscience of empathy","volume":"1156","author":"Singer","year":"2009","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/hbm.21186","article-title":"Minimizing within-experiment and within-group effects in Activation Likelihood Estimation meta-analyses","volume":"33","author":"Turkeltaub","year":"2012","journal-title":"Hum. Brain Mapp."},{"key":"B39","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/nrn3857","article-title":"Salience processing and insular cortical function and dysfunction","volume":"16","author":"Uddin","year":"2015","journal-title":"Nat. Rev. Neurosci."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1805","DOI":"10.1152\/jn.00181.2012","article-title":"Fine-grained analysis of shared neural circuits between perceived and observed pain: implications for the study of empathy for pain","volume":"108","author":"Valentini","year":"2012","journal-title":"J. Neurophysiol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1523\/JNEUROSCI.3822-08.2009","article-title":"Mood influences supraspinal pain processing separately from attention","volume":"29","author":"Villemure","year":"2009","journal-title":"J. Neurosci."},{"key":"B42","doi-asserted-by":"publisher","first-page":"1388","DOI":"10.1056\/NEJMoa1204471","article-title":"An fMRI-based neurologic signature of physical pain","volume":"368","author":"Wager","year":"2013","journal-title":"N. Engl. J. Med."},{"key":"B43","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1016\/S0896-6273(03)00679-2","article-title":"Both of us disgusted in My insula: the common neural basis of seeing and feeling disgust","volume":"40","author":"Wicker","year":"2003","journal-title":"Neuron"},{"key":"B44","doi-asserted-by":"publisher","first-page":"16324","DOI":"10.1523\/JNEUROSCI.2087-10.2010","article-title":"Anterior insula integrates information about salience into perceptual decisions about pain","volume":"30","author":"Wiech","year":"2010","journal-title":"J. Neurosci."},{"key":"B45","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.1037\/a0037679","article-title":"Empathy: a motivated account","volume":"140","author":"Zaki","year":"2014","journal-title":"Psychol. Bull."},{"key":"B46","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1038\/nn.3085","article-title":"The neuroscience of empathy: progress, pitfalls and promise","volume":"15","author":"Zaki","year":"2012","journal-title":"Nat. Neurosci."},{"key":"B47","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.tics.2016.02.003","article-title":"The anatomy of suffering: understanding the relationship between nociceptive and empathic pain","volume":"20","author":"Zaki","year":"2016","journal-title":"Trends Cogn. Sci."}],"container-title":["Frontiers in Behavioral Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fnbeh.2018.00289\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T09:33:39Z","timestamp":1543311219000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fnbeh.2018.00289\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,27]]},"references-count":47,"alternative-id":["10.3389\/fnbeh.2018.00289"],"URL":"https:\/\/doi.org\/10.3389\/fnbeh.2018.00289","relation":{},"ISSN":["1662-5153"],"issn-type":[{"value":"1662-5153","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,27]]},"article-number":"289"}}