{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T06:57:22Z","timestamp":1783234642711,"version":"3.54.6"},"reference-count":78,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T00:00:00Z","timestamp":1645401600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DA045364"],"award-info":[{"award-number":["DA045364"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DA031725"],"award-info":[{"award-number":["DA031725"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Behav. Neurosci."],"abstract":"<jats:p>Drug use is highly concordant among members of adolescent and young adult peer groups. One potential explanation for this observation is that drugs may increase the reinforcing effects of social contact, leading to greater motivation to establish and maintain contact with other members of the peer group. Several classes of drugs, particularly drugs that increase synaptic dopamine, increase the reinforcing effects of contextual stimuli, but the extent to which these drugs enhance the reinforcing effects of social contact is not known. The purpose of this study was to determine the extent to which drugs that increase synaptic dopamine, norepinephrine, and serotonin enhance the positive reinforcing effects of social contact. To this end, male and female Long-Evans rats were pretreated with acute doses of the selective dopamine reuptake inhibitor, WIN-35,428, the selective norepinephrine reuptake inhibitor, atomoxetine, the selective serotonin reuptake inhibitor, fluoxetine, the non-selective monoamine reuptake inhibitor, cocaine, and the non-selective monoamine releasers <jats:italic>d<\/jats:italic>-amphetamine and (\u00b1)-MDMA. Ten minutes later, the positive reinforcing effects of 30-s access to a same-sex social partner was examined on a progressive ratio schedule of reinforcement. To determine whether the reinforcement-altering effects of these drugs were specific to the social stimulus, the reinforcing effects of a non-social stimulus (30-s access to an athletic sock of similar size and coloring as another rat) was determined in control subjects. WIN-35,428, <jats:italic>d<\/jats:italic>-amphetamine, and cocaine, but not atomoxetine, fluoxetine, or MDMA, dose-dependently increased breakpoints maintained by a social partner under conditions in which responding maintained by a non-social stimulus was not affected. These data indicate that increases in extracellular dopamine, but not extracellular norepinephrine or serotonin, increases the positive reinforcing effects of social contact in both male and female rats. These data also provide support for the hypothesis that some drugs with high abuse liability increase the motivation to establish and maintain contact with social peers.<\/jats:p>","DOI":"10.3389\/fnbeh.2021.805139","type":"journal-article","created":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T06:11:16Z","timestamp":1645423876000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["The Effects of Drugs on Behavior Maintained by Social Contact: Role of Monoamines in Social Reinforcement"],"prefix":"10.3389","volume":"15","author":[{"given":"Jessica L.","family":"Sharp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,2,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1007\/s00213-013-3272-9","article-title":"Amphetamine and cocaine suppress social play behavior in rats through distinct mechanisms.","volume":"231","author":"Achterberg","year":"2014","journal-title":"Psychopharmacology"},{"key":"B2","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1523\/JNEUROSCI.2945-14.2015","article-title":"Methylphenidate and atomoxetine inhibit social play behavior through prefrontal and subcortical limbic mechanisms in rats.","volume":"35","author":"Achterberg","year":"2015","journal-title":"J. Neurosci."},{"key":"B3","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1038\/npp.2015.212","article-title":"Contrasting roles of dopamine and noradrenaline in the motivational properties of social play behavior in rats.","volume":"41","author":"Achterberg","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"B4","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1016\/j.biopsych.2011.11.014","article-title":"Cocaine hydrolase encoded in viral vector blocks the reinstatement of cocaine seeking in rats for 6 months.","volume":"71","author":"Anker","year":"2012","journal-title":"Biol. Psychiatry"},{"key":"B5","doi-asserted-by":"publisher","first-page":"3483","DOI":"10.1523\/JNEUROSCI.23-08-03483.2003","article-title":"A critical role for nucleus accumbens dopamine in partner-preference formation in male prairie voles.","volume":"23","author":"Aragona","year":"2003","journal-title":"J. Neurosci."},{"key":"B6","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/nn1613","article-title":"Nucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds.","volume":"9","author":"Aragona","year":"2006","journal-title":"Nat. Neurosci."},{"key":"B7","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/s0091-3057(96)00445-5","article-title":"A critique of fixed and progressive ratio schedules used to examine the neural substrates of drug reinforcement.","volume":"57","author":"Arnold","year":"1997","journal-title":"Pharmacol. Biochem. Behav."},{"key":"B8","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s10935-005-0014-8","article-title":"Parental and peer influences on the risk of adolescent drug use.","volume":"26","author":"Bahr","year":"2005","journal-title":"J. Primary Prev."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1037\/a0034687","article-title":"Peer associations for substance use and exercise in a college student social network.","volume":"33","author":"Barnett","year":"2014","journal-title":"Health Psychol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.1177\/0269881116663120","article-title":"The effects of MDMA on socio-emotional processing: Does MDMA differ from other stimulants?","volume":"30","author":"Bershad","year":"2016","journal-title":"J. Psychopharmacol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"2109","DOI":"10.1038\/s41386-018-0100-2","article-title":"Involvement of dopamine, but not norepinephrine, in the sex-specific regulation of juvenile socially rewarding behavior by vasopressin.","volume":"43","author":"Bredewold","year":"2018","journal-title":"Neuropsychopharmacology"},{"key":"B12","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/0031-9384(92)90101-7","article-title":"Place conditioning reveals the rewarding aspect of social interaction in juvenile rats.","volume":"51","author":"Calcagnetti","year":"1992","journal-title":"Physiol. Behav."},{"key":"B13","doi-asserted-by":"publisher","first-page":"406","DOI":"10.4062\/biomolther.2014.027","article-title":"Effects of atomoxetine on hyper-locomotive activity of the prenatally valproate-exposed rat offspring.","volume":"22","author":"Choi","year":"2014","journal-title":"Biomol. Therap."},{"key":"B14","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1523\/JNEUROSCI.1659-20.2020","article-title":"Hallucinogens in mental health: preclinical and clinical studies on LSD, Psilocybin, MDMA, and Ketamine.","volume":"41","author":"De Gregorio","year":"2021","journal-title":"J. Neurosci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1007\/s00213-005-0255-5","article-title":"Relevance of rodent models of intravenous MDMA self-administration to human MDMA consumption patterns.","volume":"189","author":"De La Garza","year":"2007","journal-title":"Psychopharmacology"},{"key":"B16","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1038\/nature12518","article-title":"Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin.","volume":"501","author":"D\u00f6len","year":"2013","journal-title":"Nature"},{"key":"B17","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1002\/dev.20025","article-title":"Rewarding properties of social interactions in adolescent and adult male and female rats: impact of social versus isolate housing of subjects and partners.","volume":"45","author":"Douglas","year":"2004","journal-title":"J. Int. Soc. Dev. Psychobiol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1177\/0269881106063271","article-title":"A review of acute effects of 3, 4-methylenedioxymethamphetamine in healthy volunteers.","volume":"20","author":"Dumont","year":"2006","journal-title":"J. Psychopharmacol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3389\/fnbeh.2012.00008","article-title":"Preventive role of social interaction for cocaine conditioned place preference: correlation with FosB\/DeltaFosB and pCREB expression in rat mesocorticolimbic areas.","volume":"6","author":"El Rawas","year":"2012","journal-title":"Front. Behav. Neurosci."},{"key":"B20","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.euroneuro.2017.01.003","article-title":"Effects of amphetamine on pro-social ultrasonic communication in juvenile rats: Implications for mania models.","volume":"27","author":"Engelhardt","year":"2017","journal-title":"Eur. Neuropsychopharm."},{"key":"B21","doi-asserted-by":"publisher","first-page":"261","DOI":"10.2741\/s371","article-title":"Presynaptic dopamine modulation by stimulant self administration.","volume":"5","author":"Espa\u00f1a","year":"2013","journal-title":"Front. Biosci."},{"key":"B22","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1038\/sj.npp.1300066","article-title":"Prefrontocortical dopamine loss in rats delays long-term extinction of contextual conditioned fear, and reduces social interaction without affecting short-term social interaction memory.","volume":"28","author":"Espejo","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"B23","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1901\/jeab.1994.62-149","article-title":"Social reinforcement of operant behavior in rats: a methodological note.","volume":"62","author":"Evans","year":"1994","journal-title":"J. Exp. Anal. Behav."},{"key":"B24","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1111\/j.1369-1600.2010.00285.x","article-title":"Reversal of cocaine-conditioned place preference and mesocorticolimbic Zif268 expression by social interaction in rats.","volume":"16","author":"Fritz","year":"","journal-title":"Addic. Biol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1159\/000322534","article-title":"Sigma1 receptor antagonist BD1047 enhances reversal of conditioned place preference from cocaine to social interaction.","volume":"87","author":"Fritz","year":"","journal-title":"Pharmacology"},{"key":"B26","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1038\/sj.npp.1300593","article-title":"Evaluation of the reinforcing effects of monoamine reuptake inhibitors under a concurrent schedule of food and iv drug delivery in rhesus monkeys.","volume":"30","author":"Gasior","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"B27","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1037\/bne0000258","article-title":"Noradrenergic receptor modulation influences the acoustic parameters of pro-social rat ultrasonic vocalizations.","volume":"132","author":"Grant","year":"2018","journal-title":"Behav. Neurosci."},{"key":"B28","doi-asserted-by":"publisher","first-page":"3041","DOI":"10.1007\/s00213-014-3470-0","article-title":"Effects of cocaine combined with a social cue on conditioned place preference and nucleus accumbens monoamines after isolation rearing in rats.","volume":"231","author":"Grotewold","year":"2014","journal-title":"Psychopharmacology"},{"key":"B29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2210-6-6","article-title":"Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs.","volume":"6","author":"Han","year":"2006","journal-title":"BMC Pharmacol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1111\/j.1369-1600.2008.00121.x","article-title":"Self-administration of cocaine, cannabis and heroin in the human laboratory: benefits and pitfalls.","volume":"14","author":"Haney","year":"2009","journal-title":"Addic. Biol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1126\/scitranslmed.aaw6435","article-title":"Distinct neural mechanisms for the prosocial and rewarding properties of MDMA.","volume":"11","author":"Heifets","year":"2019","journal-title":"Sci. Transl. Med."},{"key":"B32","doi-asserted-by":"publisher","first-page":"427","DOI":"10.3389\/fphar.2020.00427","article-title":"Characterization of amphetamine, methylphenidate, nicotine, and atomoxetine on measures of attention, impulsive action, and motivation in the rat: implications for translational research.","volume":"11","author":"Higgins","year":"2020","journal-title":"Front. Pharmacol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s00213-007-0895-8","article-title":"Acute and constitutive increases in central serotonin levels reduce social play behaviour in peri-adolescent rats.","volume":"195","author":"Homberg","year":"2007","journal-title":"Psychopharmacology"},{"key":"B34","doi-asserted-by":"publisher","first-page":"229","DOI":"10.3389\/fnins.2019.00229","article-title":"Subjecting dams to early life stress and perinatal fluoxetine treatment differentially alters social behavior in young and adult rat offspring.","volume":"13","author":"Houwing","year":"2019","journal-title":"Front. Neurosci."},{"key":"B35","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.neubiorev.2015.08.016","article-title":"The prosocial effects of 3, 4-methylenedioxymethamphetamine (MDMA): controlled studies in humans and laboratory animals.","volume":"57","author":"Kamilar-Britt","year":"2015","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B36","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1002\/(sici)1098-2337(1996)22:4<297::aid-ab5>3.0.co;2-i","article-title":"Effects of fluoxetine on play dominance in juvenile rats.","volume":"22","author":"Knutson","year":"1996","journal-title":"Aggr. Behav."},{"key":"B37","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1016\/j.biopsych.2014.03.031","article-title":"Preference for distinct functional conformations of the dopamine transporter alters the relationship between subjective effects of cocaine and stimulation of mesolimbic dopamine.","volume":"76","author":"Kohut","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"B38","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1074\/jbc.274.31.22081","article-title":"The neurobiology of drug addiction.","volume":"9","author":"Koob","year":"1997","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"key":"B39","doi-asserted-by":"publisher","first-page":"363","DOI":"10.3389\/fnbeh.2014.00363","article-title":"Differences in social interaction-vs cocaine reward in mouse vs rat.","volume":"8","author":"Kummer","year":"2014","journal-title":"Front. Behav. Neurosci."},{"key":"B40","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/s0306-4522(03)00555-4","article-title":"Nucleus accumbens oxytocin and dopamine interact to regulate pair bond formation in female prairie voles.","volume":"121","author":"Liu","year":"2003","journal-title":"Neuroscience"},{"key":"B41","doi-asserted-by":"publisher","first-page":"2215","DOI":"10.1038\/npp.2016.22","article-title":"Dopaminergic neurotransmission in the nucleus accumbens modulates social play behavior in rats.","volume":"41","author":"Manduca","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"B42","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1007\/s11419-018-0444-7","article-title":"MDMA alone affects sensorimotor and prepulse inhibition responses in mice and rats: tips in the debate on potential MDMA unsafety in human activity.","volume":"37","author":"Marti","year":"2019","journal-title":"Forensic Toxicol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"153","DOI":"10.3389\/fnins.2016.00153","article-title":"Neuropharmacology of new psychoactive substances (NPS): Focus on the rewarding and reinforcing properties of cannabimimetics and amphetamine-like stimulants.","volume":"10","author":"Miliano","year":"2016","journal-title":"Front. Neurosci."},{"key":"B44","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/S2215-0366(15)00576-3","article-title":"Novel psychopharmacological therapies for psychiatric disorders: psilocybin and MDMA.","volume":"3","author":"Mithoefer","year":"2016","journal-title":"Lancet Psychiatry"},{"key":"B45","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/j.pnpbp.2005.04.009","article-title":"Serotonin (1A) receptor involvement in acute 3, 4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat.","volume":"29","author":"Morley","year":"2005","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"B46","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1080\/02791072.1986.10472362","article-title":"Differences between the mechanism of action of MDMA, MBDB, and the classic hallucinogens Identification of a new therapeutic class: entactogens.","volume":"18","author":"Nichols","year":"1986","journal-title":"J. Psychoact. Drugs"},{"key":"B47","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/j.ejphar.2003.10.040","article-title":"The self-administration of WIN 35,428 and cocaine: comparisons of satiety threshold and elimination half-life in rats.","volume":"483","author":"Norman","year":"2004","journal-title":"Eur. J. Pharmacol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1007\/s00213-004-1825-7","article-title":"Effect of low doses of \u0394 9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats.","volume":"175","author":"Parker","year":"2004","journal-title":"Psychopharmacology"},{"key":"B49","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1016\/j.neubiorev.2003.11.013","article-title":"The expanding effects of cocaine: studies in a nonhuman primate model of cocaine self-administration.","volume":"27","author":"Porrino","year":"2004","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B50","doi-asserted-by":"publisher","first-page":"2631","DOI":"10.1007\/s00213-015-3899-9","article-title":"Oxytocin and MDMA (\u2018Ecstasy\u2019) enhance social reward in rats.","volume":"232","author":"Ramos","year":"2015","journal-title":"Psychopharmacology"},{"key":"B51","doi-asserted-by":"publisher","first-page":"2249","DOI":"10.1038\/npp.2013.125","article-title":"Acute prosocial effects of oxytocin and vasopressin when given alone or in combination with 3, 4-methylenedioxymethamphetamine in rats: involvement of the V1 A receptor.","volume":"38","author":"Ramos","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"B52","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1901\/jaba.2008.41-155","article-title":"On the applied use of progressive-ratio schedules of reinforcement.","volume":"41","author":"Roane","year":"2008","journal-title":"J. Appl. Behav. Anal."},{"key":"B53","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/BF00427952","article-title":"Contrasting interactions of pipradrol, d-amphetamine, cocaine, cocaine analogues, apomorphine and other drugs with conditioned reinforcement.","volume":"80","author":"Robbins","year":"1983","journal-title":"Psychopharmacology"},{"key":"B54","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1037\/a0030488","article-title":"Physical exercise and catecholamine reuptake inhibitors affect orienting behavior and social interaction in a rat model of attention-deficit\/hyperactivity disorder.","volume":"126","author":"Robinson","year":"2012","journal-title":"Behav. Neurosci."},{"key":"B55","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1097\/FBP.0b013e3282f3df9b","article-title":"Modeling the effects of fluoxetine on food-reinforced behavior.","volume":"19","author":"Sanabria","year":"2008","journal-title":"Behav. Pharmacol."},{"key":"B56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4303\/jdar\/235602","article-title":"Profile of MDMA self-administration from a large cohort of rats: MDMA Develops a profile of dependence with extended testing.","volume":"1","author":"Schenk","year":"2012","journal-title":"J. Drug Alcohol Res."},{"key":"B57","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1007\/s00213-017-4713-7","article-title":"The 21st century psychedelic renaissance: heroic steps forward on the back of an elephant.","volume":"235","author":"Sessa","year":"2018","journal-title":"Psychopharmacology"},{"key":"B58","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1093\/ijnp\/pyx106","article-title":"Modulation of rat 50-kHz ultrasonic vocalizations by glucocorticoid signaling: possible relevance to reward and motivation.","volume":"21","author":"Simola","year":"2018","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1016\/j.addbeh.2005.09.006","article-title":"Over time relationships between early adolescent and peer substance use.","volume":"31","author":"Simons-Morton","year":"2006","journal-title":"Addict. Behav."},{"key":"B60","doi-asserted-by":"publisher","first-page":"107733","DOI":"10.1016\/j.drugalcdep.2019.107733","article-title":"Nonhuman animal models of substance use disorders: Translational value and utility to basic science.","volume":"206","author":"Smith","year":"2020","journal-title":"Drug Alcohol Depend."},{"key":"B61","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/s002130050702","article-title":"Progressive-ratio schedules of drug delivery in the analysis of drug self-administration: a review.","volume":"139","author":"Stafford","year":"1998","journal-title":"Psychopharmacology"},{"key":"B62","doi-asserted-by":"publisher","first-page":"970","DOI":"10.1016\/S0893-133X(02)00379-2","article-title":"Previous exposure to VTA amphetamine enhances cocaine self-administration under a progressive ratio schedule in a D 1 dopamine receptor dependent manner.","volume":"27","author":"Suto","year":"2002","journal-title":"Neuropsychopharmacology"},{"key":"B63","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1080\/17470910802045042","article-title":"Neural correlates of MDMA (\u201cEcstasy\u201d)-induced social interaction in rats.","volume":"4","author":"Thompson","year":"2009","journal-title":"Soc. Neurosci."},{"key":"B64","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1007\/s10464-013-9569-3","article-title":"Peer substance use and homelessness predicting substance abuse from adolescence through early adulthood.","volume":"51","author":"Tompsett","year":"2013","journal-title":"Am. J. Comm. Psychol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1339","DOI":"10.1007\/s00213-013-3327-y","article-title":"Assessment of reinforcement enhancing effects of toluene vapor and nitrous oxide in intracranial self-stimulation.","volume":"231","author":"Tracy","year":"2014","journal-title":"Psychopharmacology"},{"key":"B66","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.yhbeh.2011.08.013","article-title":"Stress responses and the mesolimbic dopamine system: social contexts and sex differences.","volume":"60","author":"Trainor","year":"2011","journal-title":"Hormones Behav."},{"key":"B67","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/j.jpsychires.2003.11.007","article-title":"Effects of fluoxetine on ethanol withdrawal syndrome in rats.","volume":"38","author":"Uzbay","year":"2004","journal-title":"J. Psychiatric Res."},{"key":"B68","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.neubiorev.2016.07.025","article-title":"The neurobiology of social play and its rewarding value in rats.","volume":"70","author":"Vanderschuren","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B69","doi-asserted-by":"publisher","first-page":"2946","DOI":"10.1038\/npp.2008.10","article-title":"Methylphenidate disrupts social play behavior in adolescent rats.","volume":"33","author":"Vanderschuren","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"B70","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/0091-3057(92)90228-8","article-title":"Evaluation of the discriminative stimulus and reinforcing effects of sertraline in rhesus monkeys.","volume":"41","author":"Vanover","year":"1992","journal-title":"Pharmacol. Biochem. Behav."},{"key":"B71","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.1038\/s41596-020-0296-6","article-title":"An operant social self-administration and choice model in rats.","volume":"15","author":"Venniro","year":"2020","journal-title":"Nat. Protocols"},{"key":"B72","doi-asserted-by":"publisher","first-page":"1520","DOI":"10.1038\/s41593-018-0246-6","article-title":"Volitional social interaction prevents drug addiction in rat models.","volume":"21","author":"Venniro","year":"2018","journal-title":"Nat. Neurosci."},{"key":"B73","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.drugalcdep.2004.03.010","article-title":"Evaluation of the reinforcing effects of atomoxetine in monkeys: comparison to methylphenidate and desipramine.","volume":"75","author":"Wee","year":"2004","journal-title":"Drug Alcohol Depend."},{"key":"B74","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41421-018-0060-z","article-title":"Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA.","volume":"4","author":"Wei","year":"2018","journal-title":"Cell Discovery"},{"key":"B75","doi-asserted-by":"publisher","first-page":"10616","DOI":"10.1523\/JNEUROSCI.1060-14.2014","article-title":"Phasic dopamine release in the nucleus accumbens in response to pro-social 50 kHz ultrasonic vocalizations in rats.","volume":"34","author":"Willuhn","year":"2014","journal-title":"J. Neurosci."},{"key":"B76","first-page":"15","article-title":"Neural mechanisms of the reinforcing action of cocaine.","volume":"50","author":"Wise","year":"1984","journal-title":"NIDA Res. Monogr."},{"key":"B77","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1007\/s00213-017-4796-1","article-title":"Enhancement of a visual reinforcer by d-amphetamine and nicotine in adult rats: relation to habituation and food restriction.","volume":"235","author":"Wright","year":"2018","journal-title":"Psychopharmacology"},{"key":"B78","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.drugalcdep.2013.02.024","article-title":"Concurrent choice for social interaction and amphetamine using conditioned place preference in rats: effects of age and housing condition.","volume":"129","author":"Yates","year":"2013","journal-title":"Drug Alcohol Depend."}],"container-title":["Frontiers in Behavioral Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnbeh.2021.805139\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T06:11:23Z","timestamp":1645423883000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnbeh.2021.805139\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,21]]},"references-count":78,"alternative-id":["10.3389\/fnbeh.2021.805139"],"URL":"https:\/\/doi.org\/10.3389\/fnbeh.2021.805139","relation":{},"ISSN":["1662-5153"],"issn-type":[{"value":"1662-5153","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,21]]},"article-number":"805139"}}