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This brief review summarizes a brain network underlying social recognition memory and explores the possible relationships between social isolation and social recognition memory. Finally, we introduce some possible related molecular mechanisms underlying social recognition memory. These findings help us explore potential targeting brain areas or circuits of social communication disorder.<\/jats:p>","DOI":"10.3389\/fncir.2022.839931","type":"journal-article","created":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T18:03:12Z","timestamp":1648663392000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":47,"title":["Regulation of Social Recognition Memory in the Hippocampal Circuits"],"prefix":"10.3389","volume":"16","author":[{"given":"Xinnian","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,3,30]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-36871-6","article-title":"Social isolation impairs the persistence of social recognition memory by disturbing the glutamatergic tonus and the olfactory bulb-dorsal hippocampus coupling.","volume":"9","author":"Almeida-Santos","year":"2019","journal-title":"Sci. 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