{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T08:45:33Z","timestamp":1783413933724,"version":"3.54.6"},"reference-count":34,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Nephrol."],"abstract":"<jats:p>Living donor kidney transplantation boasts superior patient and graft survival rates compared to deceased donor kidney transplantation. However, the impact of living donor body composition (BC) on post-transplant kidney function remains uncertain. In a cohort of 293 living kidney donor-recipients pairs, we utilized linear mixed model analyses, adjusted for time and including a multiplicative interaction term of time with the donor body composition measure, and found no significant associations between any donor BC measure and the annual change in recipient post-transplantation estimated glomerular filtration rate (eGFR) [donor body mass index (BMI): <jats:italic>B<\/jats:italic>=-0.01, 95%CI -0.13; 0.11, <jats:italic>p<\/jats:italic>=0.88; donor waist circumference: <jats:italic>B<\/jats:italic>=0.02, 95%CI -0.02; 0.06, <jats:italic>p<\/jats:italic>=0.38; donor skeletal muscle index: <jats:italic>B<\/jats:italic>=-0.02, 95%CI -0.07; 0.04, <jats:italic>p<\/jats:italic>=0.63; donor skeletal muscle radiation attenuation: <jats:italic>B<\/jats:italic>=-0.002, 95%CI -0.06; 0.06, <jats:italic>p<\/jats:italic>=0.96; donor visceral adipose tissue index: <jats:italic>B<\/jats:italic>=-0.001, 95%CI -0.02; 0.02, <jats:italic>p<\/jats:italic>=0.93; donor subcutaneous adipose tissue index: <jats:italic>B<\/jats:italic>=-0.001, 95%CI -0.02; 0.02, <jats:italic>p<\/jats:italic>=0.94; donor intramuscular adipose tissue index: <jats:italic>B<\/jats:italic>=-0.12, 95%CI -0.29; 0.06, <jats:italic>p<\/jats:italic>=0.19; donor total abdominal adipose tissue index: <jats:italic>B<\/jats:italic>=-0.001, 95%CI -0.01; 0.01, <jats:italic>p<\/jats:italic>=0.89]. Our study suggests that pre-donation BC does not affect post-transplantation recipient eGFR in donor populations with a BMI below 35 kg\/m<jats:sup>2<\/jats:sup>.<\/jats:p>","DOI":"10.3389\/fneph.2024.1467669","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T06:25:42Z","timestamp":1732515942000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Analyzing body composition in living kidney donors: impact on post-transplant kidney function"],"prefix":"10.3389","volume":"4","author":[{"given":"Evelien E.","family":"Quint","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa B.","family":"Westenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gertrude J.","family":"Nieuwenhuijs-Moeke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva A. N.","family":"van den Broek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Zorgdrager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain R.","family":"Viddeleer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan J. 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